{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T12:39:41Z","timestamp":1769171981775,"version":"3.49.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Investigation"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.resinv.2020.09.010","type":"journal-article","created":{"date-parts":[[2021,1,12]],"date-time":"2021-01-12T15:48:26Z","timestamp":1610466506000},"page":"212-217","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Resumption\/efficacy and safety of an azithromycin-containing regimen against Mycobacterium avium complex lung disease in patients who experienced adverse effects with a clarithromycin-containing regimen"],"prefix":"10.1016","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2085-4292","authenticated-orcid":false,"given":"Takehiko","family":"Kobayashi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazunari","family":"Tsuyuguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8197-3829","authenticated-orcid":false,"given":"Shiomi","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yohei","family":"Kimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taisuke","family":"Tsuji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shojiro","family":"Minomo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Kurahara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshikazu","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsuhiro","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.resinv.2020.09.010_bib1","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.3201\/eid2206.151086","article-title":"Epidemiology of pulmonary nontuberculous mycobacterial disease","volume":"22","author":"Namkoong","year":"2016","journal-title":"Japan. Emerg Infect Dis"},{"key":"10.1016\/j.resinv.2020.09.010_bib2","first-page":"25","article-title":"[The non-tuberculous mycobacteriosis]","volume":"80","author":"Sakatani","year":"2005","journal-title":"Kekkaku"},{"key":"10.1016\/j.resinv.2020.09.010_bib3","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1164\/rccm.200604-571ST","article-title":"An official ATS\/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases","volume":"175","author":"Griffith","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.resinv.2020.09.010_bib4","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.rmed.2006.04.002","article-title":"A double-blind randomized study of aminoglycoside infusion with combined therapy for pulmonary Mycobacterium avium complex disease","volume":"101","author":"Kobashi","year":"2007","journal-title":"Respir Med"},{"key":"10.1016\/j.resinv.2020.09.010_bib5","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1007\/s10156-011-0351-x","article-title":"Relationship between clinical efficacy for pulmonary MAC and drug-sensitivity test for isolated MAC in a recent 6-year period","volume":"18","author":"Kobashi","year":"2012","journal-title":"J Infect Chemother"},{"key":"10.1016\/j.resinv.2020.09.010_bib6","series-title":"Susceptibility testing of mycobacteria, nocardiae, and other aerobic actinomycetes: approved standard","year":"2011"},{"key":"10.1016\/j.resinv.2020.09.010_bib7","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.1128\/AAC.02854-15","article-title":"Azithromycin dose to maximize efficacy and suppress acquired drug resistance in pulmonary mycobacterium avium disease","volume":"60","author":"Deshpande","year":"2016","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.resinv.2020.09.010_bib8","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1086\/317441","article-title":"Susceptibility testing for mycobacteria","volume":"31","author":"Woods","year":"2000","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.resinv.2020.09.010_bib9","first-page":"51","article-title":"Treatment outcome definitions in nontuberculous mycobacterial pulmonary disease: an NTM-NET consensus statement","author":"van Ingen","year":"2018","journal-title":"Eur Respir J"},{"key":"10.1016\/j.resinv.2020.09.010_bib10","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1164\/rccm.201107-1203OC","article-title":"Prognostic factors of 634 HIV-Negative patients with mycobacterium avium complex lung disease","volume":"185","author":"Hayashi","year":"2012","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.resinv.2020.09.010_bib11","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.02503-2016","article-title":"Outcomes of Mycobacterium avium complex lung disease based on clinical phenotype","volume":"50","author":"Koh","year":"2017","journal-title":"Eur Respir J"},{"key":"10.1016\/j.resinv.2020.09.010_bib12","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1378\/chest.124.4.1482","article-title":"Treatment of Mycobacterium avium-intracellulare complex lung disease with a macrolide, ethambutol, and clofazimine","volume":"124","author":"Field","year":"2003","journal-title":"Chest"},{"key":"10.1016\/j.resinv.2020.09.010_bib13","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1093\/cid\/cix517","article-title":"Treatment outcomes of Mycobacterium avium complex lung disease: a systematic review and meta-analysis","volume":"65","author":"Kwak","year":"2017","journal-title":"Clin Infect Dis : an official publication of the Infectious Diseases Society of America"},{"key":"10.1016\/j.resinv.2020.09.010_bib14","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1164\/rccm.201408-1545OC","article-title":"Intermittent antibiotic therapy for nodular bronchiectatic Mycobacterium avium complex lung disease","volume":"191","author":"Jeong","year":"2015","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.resinv.2020.09.010_bib15","first-page":"2213","article-title":"Discontinuation rates attributed to adverse events and treatment outcomes between clarithromycin and azithromycin in Mycobacterium avium complex lung disease: a propensity score analysis","author":"Kwon","year":"2020","journal-title":"J Glob Antimicrob Resist"},{"key":"10.1016\/j.resinv.2020.09.010_bib16","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.phrs.2004.01.008","article-title":"Antibacterial macrolides: a drug class with a complex pharmacological profile","volume":"50","author":"Abu-Gharbieh","year":"2004","journal-title":"Pharmacol Res"},{"key":"10.1016\/j.resinv.2020.09.010_bib17","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1164\/rccm.201204-0682OC","article-title":"The pharmacokinetics and pharmacodynamics of pulmonary Mycobacterium avium complex disease treatment","volume":"186","author":"van Ingen","year":"2012","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.resinv.2020.09.010_bib18","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1378\/chest.13-2538","article-title":"Macrolide\/Azalide therapy for nodular\/bronchiectatic mycobacterium avium complex lung disease","volume":"146","author":"Wallace","year":"2014","journal-title":"Chest"},{"key":"10.1016\/j.resinv.2020.09.010_bib19","doi-asserted-by":"crossref","first-page":"2364","DOI":"10.1128\/AAC.37.11.2364","article-title":"Mycobacterium avium strains resistant to clarithromycin and azithromycin","volume":"37","author":"Heifets","year":"1993","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.resinv.2020.09.010_bib20","doi-asserted-by":"crossref","first-page":"1904e11","DOI":"10.1513\/AnnalsATS.201604-246OC","article-title":"Macrolide-resistant Mycobacterium avium complex lung disease: analysis of 102 consecutive cases","volume":"13","author":"Morimoto","year":"2016","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.resinv.2020.09.010_bib21","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.jiac.2020.02.008","article-title":"Effective treatment for clarithromycin-resistant Mycobacterium avium complex lung disease","volume":"26","author":"Adachi","year":"2020","journal-title":"J Infect Chemother"},{"key":"10.1016\/j.resinv.2020.09.010_bib22","doi-asserted-by":"crossref","first-page":"ofz108","DOI":"10.1093\/ofid\/ofz108","article-title":"Sitafloxacin-containing regimen for the treatment of refractory Mycobacterium avium complex lung disease","volume":"6","author":"Asakura","year":"2019","journal-title":"Open Forum Infect Dis"},{"key":"10.1016\/j.resinv.2020.09.010_bib23","first-page":"395","article-title":"Measurement of sitafloxacin MIC for Mycobacterium avium complex and application for treatment of pulmonary nontuberculous mycobacteriosis","volume":"67","author":"Fujita","year":"2014","journal-title":"Jpn J Antibiot"},{"key":"10.1016\/j.resinv.2020.09.010_bib24","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.ijantimicag.2013.05.007","article-title":"Pharmacokinetic studies in patients with nontuberculous mycobacterial lung infections","volume":"42","author":"Magis-Escurra","year":"2013","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.resinv.2020.09.010_bib25","doi-asserted-by":"crossref","first-page":"6076","DOI":"10.1128\/AAC.00770-16","article-title":"Peak plasma concentration of azithromycin and treatment responses in Mycobacterium avium complex lung disease","volume":"60","author":"Jeong","year":"2016","journal-title":"Antimicrob Agents Chemother"}],"container-title":["Respiratory Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212534520301374?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212534520301374?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T22:30:26Z","timestamp":1761949826000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2212534520301374"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["S2212534520301374"],"URL":"https:\/\/doi.org\/10.1016\/j.resinv.2020.09.010","relation":{},"ISSN":["2212-5345"],"issn-type":[{"value":"2212-5345","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Resumption\/efficacy and safety of an azithromycin-containing regimen against Mycobacterium avium complex lung disease in patients who experienced adverse effects with a clarithromycin-containing regimen","name":"articletitle","label":"Article Title"},{"value":"Respiratory Investigation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.resinv.2020.09.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}