{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T07:56:40Z","timestamp":1784275000541,"version":"3.55.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Investigation"],"published-print":{"date-parts":[[2023,7]]},"DOI":"10.1016\/j.resinv.2023.03.010","type":"journal-article","created":{"date-parts":[[2023,4,24]],"date-time":"2023-04-24T12:56:02Z","timestamp":1682340962000},"page":"409-417","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Impact of adding pethidine on disinhibition during bronchoscopy with midazolam: a propensity score matching analysis"],"prefix":"10.1016","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6546-6376","authenticated-orcid":false,"given":"Takeshi","family":"Matsumoto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akiko","family":"Kaneko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Fujiki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Kusakabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emi","family":"Nakayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayaka","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9259-6256","authenticated-orcid":false,"given":"Kensaku","family":"Aihara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinpachi","family":"Yamaoka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michiaki","family":"Mishima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Suppl 1","key":"10.1016\/j.resinv.2023.03.010_bib1","doi-asserted-by":"crossref","first-page":"i1","DOI":"10.1136\/thoraxjnl-2013-203618","article-title":"British Thoracic Society guideline for diagnostic flexible bronchoscopy in adults: accredited by NICE","volume":"68","author":"Du Rand","year":"2013","journal-title":"Thorax"},{"key":"10.1016\/j.resinv.2023.03.010_bib2","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1378\/chest.10-3361","article-title":"American College of Chest Physicians consensus statement on the use of topical anesthesia, analgesia, and sedation during flexible bronchoscopy in adult patients","volume":"140","author":"Wahidi","year":"2011","journal-title":"Chest"},{"key":"10.1016\/j.resinv.2023.03.010_bib3","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1183\/09059180.00006412","article-title":"Sedation for flexible bronchoscopy: current and emerging evidence","volume":"22","author":"Jos\u00e9","year":"2013","journal-title":"Eur Respir Rev"},{"key":"10.1016\/j.resinv.2023.03.010_bib4","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1097\/LBR.0000000000000261","article-title":"A prospective analysis of the efficacy and complications associated with deep sedation with midazolam during fiberoptic bronchoscopy","volume":"23","author":"Haga","year":"2016","journal-title":"J Bronchology Interv Pulmonol"},{"key":"10.1016\/j.resinv.2023.03.010_bib5","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.resinv.2018.12.007","article-title":"Current status of diagnostic and therapeutic bronchoscopy in Japan: 2016 national survey of bronchoscopy","volume":"57","author":"Horinouchi","year":"2019","journal-title":"Respir Investig"},{"key":"10.1016\/j.resinv.2023.03.010_bib6","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.resinv.2021.11.010","article-title":"Prevalence and characteristics of disinhibition during bronchoscopy with midazolam","volume":"60","author":"Matsumoto","year":"2022","journal-title":"Respir Investig"},{"key":"10.1016\/j.resinv.2023.03.010_bib7","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1159\/000267227","article-title":"Sedation during flexible bronchoscopy in patients with pre-existing respiratory failure: midazolam versus Midazolam plus Alfentanil","volume":"79","author":"Dreher","year":"2010","journal-title":"Respiration"},{"key":"10.1016\/j.resinv.2023.03.010_bib8","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1136\/thx.2003.019836","article-title":"Cough suppression during flexible bronchoscopy using combined sedation with midazolam and hydrocodone: a randomised, double blind, placebo controlled trial","volume":"59","author":"Stolz","year":"2004","journal-title":"Thorax"},{"key":"10.1016\/j.resinv.2023.03.010_bib9","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1186\/s12885-022-09640-y","article-title":"Randomized single-blind comparative study of the midazolam\/pethidine combination and midazolam alone during bronchoscopy","volume":"22","author":"Katsurada","year":"2022","journal-title":"BMC Cancer"},{"key":"10.1016\/j.resinv.2023.03.010_bib10","doi-asserted-by":"crossref","first-page":"352","DOI":"10.2165\/00003088-197803050-00002","article-title":"Clinical pharmacokinetics of pethidine","volume":"3","author":"Mather","year":"1978","journal-title":"Clin Pharmacokinet"},{"key":"10.1016\/j.resinv.2023.03.010_bib11","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1016\/j.dld.2014.04.007","article-title":"Paradoxical reaction to midazolam in patients undergoing endoscopy under sedation: incidence, risk factors and the effect of flumazenil","volume":"46","author":"Tae","year":"2014","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.resinv.2023.03.010_bib12","doi-asserted-by":"crossref","first-page":"659","DOI":"10.3892\/etm.2015.2547","article-title":"Evaluation of discomfort and tolerability to bronchoscopy according to different sedation procedures with midazolam","volume":"10","author":"Matsumoto","year":"2015","journal-title":"Exp Ther Med"},{"key":"10.1016\/j.resinv.2023.03.010_bib13","first-page":"244","article-title":"Validity and reliability of the Observer's Assessment of Alertness\/Sedation Scale: study with intravenous midazolam","volume":"10","author":"Chernik","year":"1990","journal-title":"J Clin Psychopharmacol"},{"key":"10.1016\/j.resinv.2023.03.010_bib14","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1600-0447.1983.tb09716.x","article-title":"The hospital anxiety and depression scale","volume":"67","author":"Zigmond","year":"1983","journal-title":"Acta Psychiatr Scand"},{"key":"10.1016\/j.resinv.2023.03.010_bib15","first-page":"3","article-title":"Proposal for safe bronchoscopy which considers patient satisfaction based on a bronchoscopic examination questionnaire","volume":"33","author":"Fujisawa","year":"2011","journal-title":"J Jpn Soc Resp Endoscopy"},{"key":"10.1016\/j.resinv.2023.03.010_bib16","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1093\/jjco\/hyw083","article-title":"Safety and discomfort during bronchoscopy performed under sedation with fentanyl and midazolam: a prospective study","volume":"46","author":"Minami","year":"2016","journal-title":"Jpn J Clin Oncol"},{"key":"10.1016\/j.resinv.2023.03.010_bib17","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1002\/pst.433","article-title":"Optimal caliper widths for propensity-score matching when estimating differences in means and differences in proportions in observational studies","volume":"10","author":"Austin","year":"2011","journal-title":"Pharmaceut Stat"},{"key":"10.1016\/j.resinv.2023.03.010_bib18","unstructured":"propensityscore201412.pdf. Available from: https:\/\/www.jmp.com\/content\/dam\/jmp\/documents\/jp\/support\/propensityscore201412.pdf [accessed 2022 September 30]."},{"key":"10.1016\/j.resinv.2023.03.010_bib19","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1053\/j.gastro.2007.06.002","article-title":"AGA Institute review of endoscopic sedation","volume":"133","author":"Cohen","year":"2007","journal-title":"Gastroenterology"},{"key":"10.1016\/j.resinv.2023.03.010_bib20","first-page":"417","article-title":"A feasibility study of sedation with midazolam and pethidine hydrochloride during bronchoscopy assessed by a patient pain questionnaire","volume":"40","author":"Sakai","year":"2018","journal-title":"J Jpn Soc Respir Endoscopy"},{"key":"10.1016\/j.resinv.2023.03.010_bib21","doi-asserted-by":"crossref","first-page":"768","DOI":"10.4081\/monaldi.2017.768","article-title":"Endobronchial ultrasound-guided transbronchial needle aspiration under conscious sedation with meperidine and midazolam","volume":"87","author":"Agostini","year":"2017","journal-title":"Monaldi Arch Chest Dis"},{"key":"10.1016\/j.resinv.2023.03.010_bib22","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1111\/1759-7714.14286","article-title":"Efficacy and safety of EBUS-TBNA under conscious sedation with meperidine and midazolam","volume":"13","author":"Piro","year":"2022","journal-title":"Thorac Cancer"},{"key":"10.1016\/j.resinv.2023.03.010_bib23","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1097\/00000542-199011000-00005","article-title":"Frequent hypoxemia and apnea after sedation with midazolam and fentanyl","volume":"73","author":"Bailey","year":"1990","journal-title":"Anesthesiology"},{"key":"10.1016\/j.resinv.2023.03.010_bib24","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1093\/bja\/aer275","article-title":"Increase of paradoxical excitement response during propofol-induced sedation in hazardous and harmful alcohol drinkers","volume":"107","author":"Jeong","year":"2011","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.resinv.2023.03.010_bib25","first-page":"S2212","article-title":"Safe sedation during diagnostic and therapeutic flexible bronchoscopy in Japan: a review of the literature","author":"Minami","year":"2022","journal-title":"Respir Investig"},{"key":"10.1016\/j.resinv.2023.03.010_bib26","first-page":"74","article-title":"Sedation in outpatient flexible bronchoscopy: alfentanil-propofol versus meperidine-midazolam","volume":"6","author":"Matot","year":"1999","journal-title":"J Bronchology Interv Pulmonol"},{"key":"10.1016\/j.resinv.2023.03.010_bib27","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0138422","article-title":"Conventional versus analgesia-oriented combination sedation on recovery profiles and satisfaction after ERCP: a randomized trial","volume":"10","author":"Shin","year":"2015","journal-title":"PLoS One"}],"container-title":["Respiratory Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212534523000400?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212534523000400?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T22:32:48Z","timestamp":1761949968000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2212534523000400"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["S2212534523000400"],"URL":"https:\/\/doi.org\/10.1016\/j.resinv.2023.03.010","relation":{},"ISSN":["2212-5345"],"issn-type":[{"value":"2212-5345","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of adding pethidine on disinhibition during bronchoscopy with midazolam: a propensity score matching analysis","name":"articletitle","label":"Article Title"},{"value":"Respiratory Investigation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.resinv.2023.03.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}