{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T13:12:51Z","timestamp":1778850771771,"version":"3.51.4"},"reference-count":25,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Investigation"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.resinv.2026.101416","type":"journal-article","created":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T11:12:36Z","timestamp":1774437156000},"page":"101416","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Helmet noninvasive ventilation in patients with COVID-19-related acute hypoxemic respiratory failure: A Japanese single-center experience"],"prefix":"10.1016","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8100-5505","authenticated-orcid":false,"given":"Toshiki","family":"Yokoyama","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9764-0126","authenticated-orcid":false,"given":"Ryo","family":"Teramachi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaho","family":"Hiramitsu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Hagimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reoto","family":"Takei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7368-3004","authenticated-orcid":false,"given":"Yoshikazu","family":"Mutoh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hajime","family":"Sasano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Fukihara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhiko","family":"Yamano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3944-6881","authenticated-orcid":false,"given":"Kensuke","family":"Kataoka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9745-3329","authenticated-orcid":false,"given":"Tomoki","family":"Kimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhiro","family":"Kondoh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.resinv.2026.101416_bib1","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1056\/NEJMoa2001017","article-title":"A novel coronavirus from patients with pneumonia in China, 2019","volume":"382","author":"Zhu","year":"2020","journal-title":"N Engl J Med"},{"key":"10.1016\/j.resinv.2026.101416_bib2","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0140-6736(20)30183-5","article-title":"Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China","volume":"395","author":"Huang","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.resinv.2026.101416_bib3","doi-asserted-by":"crossref","first-page":"2052","DOI":"10.1001\/jama.2020.6775","article-title":"Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area","volume":"323","author":"Richardson","year":"2020","journal-title":"JAMA"},{"key":"10.1016\/j.resinv.2026.101416_bib4","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1001\/jama.2020.5394","article-title":"Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy Region, Italy","volume":"323","author":"Grasselli","year":"2020","journal-title":"JAMA"},{"key":"10.1016\/j.resinv.2026.101416_bib5","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1164\/rccm.201605-1081CP","article-title":"Mechanical ventilation to minimize progression of lung injury in acute respiratory failure","volume":"195","author":"Brochard","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.resinv.2026.101416_bib6","doi-asserted-by":"crossref","first-page":"2329","DOI":"10.1001\/jama.2020.6825","article-title":"Management of COVID-19 respiratory distress","volume":"323","author":"Marini","year":"2020","journal-title":"JAMA"},{"key":"10.1016\/j.resinv.2026.101416_bib7","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.1001\/jama.2021.20714","article-title":"Effect of high-flow oxygen therapy vs conventional oxygen therapy on invasive mechanical ventilation and clinical recovery in patients with severe COVID-19: a randomized clinical trial","volume":"326","author":"Ospina-Tasc\u00f3n","year":"2021","journal-title":"JAMA"},{"key":"10.1016\/j.resinv.2026.101416_bib8","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1001\/jama.2022.0028","article-title":"Effect of noninvasive respiratory strategies on intubation or mortality among patients with acute hypoxemic respiratory failure and COVID-19: the RECOVERY-RS randomized clinical trial","volume":"327","author":"Perkins","year":"2022","journal-title":"JAMA"},{"key":"10.1016\/j.resinv.2026.101416_bib9","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1001\/jama.2021.4682","article-title":"Effect of helmet noninvasive ventilation vs high-flow nasal oxygen on days free of respiratory support in patients with COVID-19 and moderate to severe hypoxemic respiratory failure: the HENIVOT randomized clinical trial","volume":"325","author":"Grieco","year":"2021","journal-title":"JAMA"},{"key":"10.1016\/j.resinv.2026.101416_bib10","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.resinv.2021.10.005","article-title":"High-flow nasal cannula oxygen therapy in hypoxic patients with COVID-19 pneumonia: a retrospective cohort study confirming the utility of respiratory rate index","volume":"60","author":"Takeshita","year":"2022","journal-title":"Respir Investig"},{"key":"10.1016\/j.resinv.2026.101416_bib11","doi-asserted-by":"crossref","first-page":"47","DOI":"10.35772\/ghm.2022.01054","article-title":"High-flow nasal cannula for severe COVID-19 patients in a Japanese single-center, retrospective, observational study: 1 year of clinical experience","volume":"5","author":"Katsuno","year":"2023","journal-title":"Glob Health Med"},{"key":"10.1016\/j.resinv.2026.101416_bib12","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1016\/j.resinv.2025.06.013","article-title":"Clinical outcomes, safety, and potential prognostic factors of noninvasive respiratory support in patients with COVID-19: a Japanese multicenter observational study","volume":"63","author":"Ito","year":"2025","journal-title":"Respir Investig"},{"key":"10.1016\/j.resinv.2026.101416_bib13","doi-asserted-by":"crossref","first-page":"2077","DOI":"10.2169\/internalmedicine.49.3749","article-title":"Noninvasive ventilation in patients with acute exacerbation of pulmonary tuberculosis sequelae","volume":"49","author":"Aso","year":"2010","journal-title":"Intern Med"},{"key":"10.1016\/j.resinv.2026.101416_bib14","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.2169\/internalmedicine.49.3222","article-title":"Noninvasive ventilation in acute exacerbation of idiopathic pulmonary fibrosis","volume":"49","author":"Yokoyama","year":"2010","journal-title":"Intern Med"},{"key":"10.1016\/j.resinv.2026.101416_bib15","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.jcrc.2016.05.022","article-title":"Predicting success of high-flow nasal cannula in pneumonia patients with hypoxemic respiratory failure: the utility of the ROX index","volume":"35","author":"Roca","year":"2016","journal-title":"J Crit Care"},{"key":"10.1016\/j.resinv.2026.101416_bib16","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1186\/s13054-022-04060-7","article-title":"An updated HACOR score for predicting the failure of noninvasive ventilation: a multicenter prospective observational study","volume":"26","author":"Duan","year":"2022","journal-title":"Crit Care"},{"key":"10.1016\/j.resinv.2026.101416_bib17","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1056\/NEJMoa1503326","article-title":"High-flow oxygen through nasal cannula in acute hypoxemic respiratory failure","volume":"372","author":"Frat","year":"2015","journal-title":"N Engl J Med"},{"key":"10.1016\/j.resinv.2026.101416_bib18","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1038\/bmt.2012.244","article-title":"Investigation of the freely available easy-to-use software \u201cEZR\u201d for medical statistics","volume":"48","author":"Kanda","year":"2013","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.resinv.2026.101416_bib19","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1111\/resp.14588","article-title":"Continuous positive airway pressure versus high-flow nasal cannula oxygen therapy for acute hypoxemic respiratory failure: a randomized controlled trial","volume":"29","author":"Nagata","year":"2024","journal-title":"Respirology"},{"key":"10.1016\/j.resinv.2026.101416_bib20","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1097\/00003246-200203000-00019","article-title":"New treatment of acute hypoxemic respiratory failure: noninvasive pressure support ventilation delivered by helmet\u2014a pilot controlled trial","volume":"30","author":"Antonelli","year":"2002","journal-title":"Crit Care Med"},{"key":"10.1016\/j.resinv.2026.101416_bib21","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1007\/s00134-014-3325-5","article-title":"Helmet CPAP vs. oxygen therapy in severe hypoxemic respiratory failure due to pneumonia","volume":"40","author":"Brambilla","year":"2014","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.resinv.2026.101416_bib22","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1164\/rccm.201904-0841OC","article-title":"Physiological comparison of high-flow nasal cannula and helmet noninvasive ventilation in acute hypoxemic respiratory failure","volume":"201","author":"Grieco","year":"2020","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.resinv.2026.101416_bib23","doi-asserted-by":"crossref","first-page":"2435","DOI":"10.1001\/jama.2016.6338","article-title":"Effect of noninvasive ventilation delivered by helmet vs face mask on the rate of endotracheal intubation in patients with acute respiratory distress syndrome: a randomized clinical trial","volume":"315","author":"Patel","year":"2016","journal-title":"JAMA"},{"key":"10.1016\/j.resinv.2026.101416_bib24","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1001\/jama.2020.9524","article-title":"Association of noninvasive oxygenation strategies with all-cause mortality in adults with acute hypoxemic respiratory failure: a systematic review and meta-analysis","volume":"324","author":"Ferreyro","year":"2020","journal-title":"JAMA"},{"key":"10.1016\/j.resinv.2026.101416_bib25","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/j.chest.2023.04.022","article-title":"Noninvasive oxygenation strategies in adult patients with acute hypoxemic respiratory failure: a systematic review and network meta-analysis","volume":"164","author":"Pitre","year":"2023","journal-title":"Chest"}],"container-title":["Respiratory Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S221253452600050X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S221253452600050X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T12:57:32Z","timestamp":1778849852000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S221253452600050X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["S221253452600050X"],"URL":"https:\/\/doi.org\/10.1016\/j.resinv.2026.101416","relation":{},"ISSN":["2212-5345"],"issn-type":[{"value":"2212-5345","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Helmet noninvasive ventilation in patients with COVID-19-related acute hypoxemic respiratory failure: A Japanese single-center experience","name":"articletitle","label":"Article Title"},{"value":"Respiratory Investigation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.resinv.2026.101416","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier B.V. on behalf of The Japanese Respiratory Society.","name":"copyright","label":"Copyright"}],"article-number":"101416"}}