{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T12:07:17Z","timestamp":1784030837209,"version":"3.55.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Investigation"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.resinv.2026.101454","type":"journal-article","created":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:27:37Z","timestamp":1780360057000},"page":"101454","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical features of macrolide-resistant Mycoplasma pneumoniae pneumonia: Can the JRS pneumonia guidelines be applied?"],"prefix":"10.1016","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3730-4908","authenticated-orcid":false,"given":"Naoyuki","family":"Miyashita","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makoto","family":"Ogata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Fukuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihisa","family":"Yamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5419-9156","authenticated-orcid":false,"given":"Tomoki","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.resinv.2026.101454_bib1","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1111\/j.1348-0421.2001.tb01293.x","article-title":"Characteristics of macrolide-resistant Mycoplasma pneumoniae strains isolated from patients and induced with erythromycin in vitro","volume":"45","author":"Okazaki","year":"2001","journal-title":"Microbiol Immunol"},{"key":"10.1016\/j.resinv.2026.101454_bib2","doi-asserted-by":"crossref","first-page":"4046","DOI":"10.1128\/AAC.00663-13","article-title":"Nationwide surveillance of macrolide-resistant Mycoplasma pneumoniae infection in pediatric patients","volume":"57","author":"Kawai","year":"2013","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.resinv.2026.101454_bib3","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.3201\/eid2310.170106","article-title":"Macrolide-resistant Mycoplasma pneumoniae infection, Japan, 2008-2015","volume":"23","author":"Tanaka","year":"2017","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.resinv.2026.101454_bib4","doi-asserted-by":"crossref","first-page":"385","DOI":"10.3389\/fcimb.2020.00385","article-title":"Periodic genotype shifts in clinically prevalent Mycoplasma pneumoniae strains in Japan","volume":"10","author":"Kenri","year":"2020","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.resinv.2026.101454_bib5","doi-asserted-by":"crossref","DOI":"10.1099\/jmm.0.001365","article-title":"P1 gene of Mycoplasma pneumoniae isolated from 2016 to 2019 and relationship between genotyping and macrolide resistance in Hokkaido, Japan","volume":"70","author":"Ishiguro","year":"2021","journal-title":"J Med Microbiol"},{"key":"10.1016\/j.resinv.2026.101454_bib6","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.jiac.2020.10.007","article-title":"Recent acute reduction in macrolide-resistant Mycoplasma pneumoniae infections among Japanese children","volume":"27","author":"Nakamura","year":"2021","journal-title":"J Infect Chemother"},{"key":"10.1016\/j.resinv.2026.101454_bib7","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.resinv.2025.04.009","article-title":"Macrolide-resistant Mycoplasma pneumoniae infection prevalence increases again in Osaka","volume":"63","author":"Miyashita","year":"2025","journal-title":"Respir Investig"},{"key":"10.1016\/j.resinv.2026.101454_bib8","doi-asserted-by":"crossref","first-page":"5181","DOI":"10.1128\/AAC.00737-13","article-title":"Macrolide-resistant Mycoplasma pneumoniae pneumonia in adolescents and adults: clinical findings, drug susceptibility and therapeutic efficacy","volume":"57","author":"Miyashita","year":"2013","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.resinv.2026.101454_bib9","doi-asserted-by":"crossref","first-page":"2252","DOI":"10.1128\/AAC.00048-13","article-title":"Therapeutic efficacy of macrolides, minocycline, and tosufloxacin against macrolide-resistant Mycoplasma pneumoniae pneumonia in pediatric patients","volume":"57","author":"Kawai","year":"2013","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.resinv.2026.101454_bib10","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.resinv.2025.06.014","article-title":"The JRS guideline for the management of pneumonia in adults 2024","volume":"63","author":"Mukae","year":"2025","journal-title":"Respir Investig"},{"key":"10.1016\/j.resinv.2026.101454_bib11","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.jgar.2022.01.002","article-title":"Molecular features and antimicrobial susceptibility of Mycoplasma pneumoniae isolates from paediatric inpatients in Weihai, China: characteristics of M. pneumoniae in Weihai","volume":"28","author":"Guo","year":"2022","journal-title":"J Glob Antimicrob Resist"},{"key":"10.1016\/j.resinv.2026.101454_bib12","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/s12866-024-03180-0","article-title":"Molecular epidemiology of Mycoplasma pneumoniae pneumonia in children, Wuhan, 2020-2022","volume":"24","author":"Xu","year":"2024","journal-title":"BMC Microbiol"},{"key":"10.1016\/j.resinv.2026.101454_bib13","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1111\/j.1440-1843.2012.02188.x","article-title":"Influence of age in the clinical differentiation of atypical pneumonia in adults","volume":"17","author":"Miyashita","year":"2012","journal-title":"Respirology"},{"issue":"Suppl 3","key":"10.1016\/j.resinv.2026.101454_bib14","first-page":"S79","article-title":"Guidelines for the management of community acquired pneumonia in adults, revised edition","volume":"11","year":"2006","journal-title":"Respirology"},{"key":"10.1016\/j.resinv.2026.101454_bib15","article-title":"Increased macrolide resistance rate of Mycoplasma pneumoniae correlated with epidemic in Beijing, China in 2023","volume":"15","author":"Chen","year":"2024","journal-title":"Front Microbiol"},{"key":"10.1016\/j.resinv.2026.101454_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2024.e33697","article-title":"Macrolide-resistant mycoplasma pneumoniae infection in children observed during a period of high incidence in Henan, China","volume":"10","author":"Leng","year":"2024","journal-title":"Heliyon"},{"key":"10.1016\/j.resinv.2026.101454_bib17","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2024.1427702","article-title":"An outbreak of Mycoplasma pneumoniae in children after the COVID-19 pandemic, Shanghai, China, 2023","volume":"15","author":"Zhu","year":"2024","journal-title":"Front Microbiol"},{"key":"10.1016\/j.resinv.2026.101454_bib18","doi-asserted-by":"crossref","first-page":"e100","DOI":"10.1016\/S2666-5247(23)00344-0","article-title":"Mycoplasma pneumoniae: delayed re-emergence after COVID-19 pandemic restrictions","volume":"5","author":"Meyer Sauteur","year":"2024","journal-title":"Lancet Microbe"},{"key":"10.1016\/j.resinv.2026.101454_bib19","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.00255-25","article-title":"Therapeutic efficacy of lascufloxacin in patients with Mycoplasma pneumoniae pneumonia","volume":"13","author":"Miyashita","year":"2025","journal-title":"Microbiol Spectr"},{"key":"10.1016\/j.resinv.2026.101454_bib20","doi-asserted-by":"crossref","DOI":"10.1128\/aac.00025-26","article-title":"Efficacy of garenoxacin in patients with Mycoplasma pneumoniae pneumonia","author":"Miyashita","year":"2026","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.resinv.2026.101454_bib21","series-title":"Guiding principles for treating Mycoplasma pneumoniae pneumonia","year":"2014"},{"key":"10.1016\/j.resinv.2026.101454_bib22","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.ejrad.2008.08.004","article-title":"Differentiation of bacterial and non-bacterial community-acquired pneumonia by thin-section computed tomography","volume":"72","author":"Ito","year":"2009","journal-title":"Eur J Radiol"},{"key":"10.1016\/j.resinv.2026.101454_bib23","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1471-2342-9-7","article-title":"Radiographic features of Mycoplasma pneumoniae pneumonia: differential diagnosis and performance timing","volume":"9","author":"Miyashita","year":"2009","journal-title":"BMC Med Imag"},{"key":"10.1016\/j.resinv.2026.101454_bib24","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1016\/j.chest.2020.06.025","article-title":"Chest CT imaging signature of coronavirus disease 2019 infection: in pursuit of scientific evidence","volume":"158","author":"Adams","year":"2020","journal-title":"Chest"},{"key":"10.1016\/j.resinv.2026.101454_bib25","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.21037\/qims-20-564","article-title":"A systematic review of chest imaging in COVID-19","volume":"10","author":"Sun","year":"2020","journal-title":"Quant Imag Med Surg"},{"key":"10.1016\/j.resinv.2026.101454_bib26","doi-asserted-by":"crossref","DOI":"10.1148\/ryct.2020200152","article-title":"Radiological Society of North America Expert Consensus Document on reporting chest CT findings related to COVID-19: endorsed by the Society of Thoracic Radiology, the American College of Radiology, and RSNA","volume":"2","author":"Simpson","year":"2020","journal-title":"Radiol Cardiothor Imaging"},{"key":"10.1016\/j.resinv.2026.101454_bib27","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1016\/j.jiac.2022.02.005","article-title":"Early identification of novel coronavirus (COVID-19) pneumonia using clinical and radiographic findings","volume":"28","author":"Miyashita","year":"2022","journal-title":"J Infect Chemother"}],"container-title":["Respiratory Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212534526000882?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212534526000882?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T11:41:18Z","timestamp":1784029278000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2212534526000882"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["S2212534526000882"],"URL":"https:\/\/doi.org\/10.1016\/j.resinv.2026.101454","relation":{},"ISSN":["2212-5345"],"issn-type":[{"value":"2212-5345","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical features of macrolide-resistant Mycoplasma pneumoniae pneumonia: Can the JRS pneumonia guidelines be applied?","name":"articletitle","label":"Article Title"},{"value":"Respiratory Investigation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.resinv.2026.101454","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Japanese Respiratory Society. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"101454"}}