{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T19:12:03Z","timestamp":1791832323579,"version":"4.3.4"},"reference-count":44,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T00:00:00Z","timestamp":1700611200000},"content-version":"vor","delay-in-days":2273,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Science Foundation of China","doi-asserted-by":"publisher","award":["21275066"],"award-info":[{"award-number":["21275066"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Six Talent Peak Program at 2016","award":["SWYY-126"],"award-info":[{"award-number":["SWYY-126"]}]},{"name":"Fundamental Research of Doctor of Philosophy at 2014","award":["2050205"],"award-info":[{"award-number":["2050205"]}]},{"name":"Fundamental Research of Doctor of Philosophy at 2015","award":["205020502"],"award-info":[{"award-number":["205020502"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Research in Microbiology"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1016\/j.resmic.2017.05.002","type":"journal-article","created":{"date-parts":[[2017,5,30]],"date-time":"2017-05-30T05:06:45Z","timestamp":1496120805000},"page":"664-672","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"title":["Characterization of a major facilitator superfamily transporter in Shiraia bambusicola"],"prefix":"10.1016","volume":"168","author":[{"given":"Huaxiang","family":"Deng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruijie","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangru","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujie","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.resmic.2017.05.002_bib1","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.fgb.2008.11.007","article-title":"The ABC transporter ATR1 is necessary for efflux of the toxin cercosporin in the fungus Cercospora nicotianae","volume":"46","author":"Amnuaykanjanasin","year":"2009","journal-title":"Fungal Genet Biol"},{"key":"10.1016\/j.resmic.2017.05.002_bib2","doi-asserted-by":"crossref","first-page":"2543","DOI":"10.1002\/bit.25662","article-title":"Tailor-made CRISPR\/Cas system for highly efficient targeted gene replacement in the rice blast fungus","volume":"112","author":"Arazoe","year":"2015","journal-title":"Biotechnol Bioeng"},{"key":"10.1016\/j.resmic.2017.05.002_bib3","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1007\/s00294-015-0486-x","article-title":"Membrane transporters in self resistance of Cercospora nicotianae to the photoactivated toxin cercosporin","volume":"61","author":"Beseli","year":"2015","journal-title":"Curr Genet"},{"key":"10.1016\/j.resmic.2017.05.002_bib4","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1038\/nrmicro2916","article-title":"Regulation of fungal secondary metabolism","volume":"11","author":"Brakhage","year":"2013","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.resmic.2017.05.002_bib5","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.nbt.2011.02.001","article-title":"Induction of hypocrellin production by Triton X-100 under submerged fermentation with Shiraia sp. SUPER-H168","volume":"28","author":"Cai","year":"2011","journal-title":"New Biotechnol"},{"key":"10.1016\/j.resmic.2017.05.002_bib6","first-page":"1880","article-title":"The structure of hypocrellin and its photo-oxidation product peroxyhyprocrellin","author":"Chen","year":"1981","journal-title":"Liebigs Ann Der Chem"},{"key":"10.1016\/j.resmic.2017.05.002_bib7","first-page":"339","article-title":"Phylogenetic study on Shiraia bambusicola by rDNA sequence analyses","volume":"44","author":"Cheng","year":"2004","journal-title":"J\u00a0Basic Microbiol"},{"key":"10.1016\/j.resmic.2017.05.002_bib8","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1094\/MPMI-18-0468","article-title":"The CTB1 gene encoding a fungal polyketide synthase is required for cercosporin biosynthesis and fungal virulence of Cercospora nicotianae","volume":"18","author":"Choquer","year":"2005","journal-title":"Mol Plant Microbe Interact"},{"key":"10.1016\/j.resmic.2017.05.002_bib9","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.febslet.2007.01.011","article-title":"Deletion of a MFS transporter-like gene in Cercospora nicotianae reduces cercosporin toxin accumulation and fungal virulence","volume":"581","author":"Choquer","year":"2007","journal-title":"FEBS Lett"},{"key":"10.1016\/j.resmic.2017.05.002_bib10","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/S0006-291X(03)00171-2","article-title":"The CRG1 gene required for resistance to the singlet oxygen-generating cercosporin toxin in Cercospora nicotianae encodes a putative fungal transcription factor","volume":"302","author":"Chung","year":"2003","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.resmic.2017.05.002_bib11","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1099\/mic.0.000043","article-title":"FUBT, a putative MFS transporter, promotes secretion of fusaric acid in the cotton pathogen Fusarium oxysporum f. sp vasinfectum","volume":"161","author":"Crutcher","year":"2015","journal-title":"Microbiology"},{"key":"10.1016\/j.resmic.2017.05.002_bib12","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1089\/ars.2012.5080","article-title":"Reactive oxygen species in plant pathogenesis: the role of perylenequinone photosensitizers","volume":"19","author":"Daub","year":"2013","journal-title":"Antioxid Redox Signal"},{"key":"10.1016\/j.resmic.2017.05.002_bib13","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.3390\/molecules21091118","article-title":"Adaptive responses to oxidative stress in the filamentous fungal Shiraia bambusicola","volume":"21","author":"Deng","year":"2016","journal-title":"Molecules"},{"key":"10.1016\/j.resmic.2017.05.002_bib14","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1016\/j.procbio.2016.07.013","article-title":"An efficient polyethylene glycol-mediated transformation system of lentiviral vector in Shiraia bambusicola","volume":"51","author":"Deng","year":"2016","journal-title":"Process Biochem"},{"key":"10.1016\/j.resmic.2017.05.002_bib15","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.gene.2016.01.019","article-title":"Reference genes selection and relative expression analysis from Shiraia sp. SUPER-H168 productive of hypocrellin","volume":"580","author":"Deng","year":"2016","journal-title":"Gene"},{"key":"10.1016\/j.resmic.2017.05.002_bib16","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/mpp.12318","article-title":"Efficient disruption and replacement of an effector gene in the oomycete Phytophthora sojae using CRISPR\/Cas9","volume":"17","author":"Fang","year":"2016","journal-title":"Mol Plant Pathol"},{"key":"10.1016\/j.resmic.2017.05.002_bib17","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1038\/nmeth.2532","article-title":"Heritable genome editing in C. elegans via a CRISPR\u2013Cas9 system","volume":"10","author":"Friedland","year":"2013","journal-title":"Nat Meth"},{"key":"10.1016\/j.resmic.2017.05.002_bib18","doi-asserted-by":"crossref","first-page":"e187","DOI":"10.1093\/nar\/gkt772","article-title":"Efficient generation of large-scale genome-modified mice using gRNA and Cas9 endonuclease","volume":"41","author":"Fujii","year":"2013","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.resmic.2017.05.002_bib19","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1128\/EC.00107-15","article-title":"Development of the CRISPR\/Cas9 system for targeted gene disruption in Aspergillus fumigatus","volume":"14","author":"Fuller","year":"2015","journal-title":"Eukaryot Cell"},{"key":"10.1016\/j.resmic.2017.05.002_bib20","doi-asserted-by":"crossref","first-page":"8030","DOI":"10.1021\/nn302634m","article-title":"Hypocrellin-loaded gold nanocages with high two-photon efficiency for photothermal\/photodynamic cancer therapy in\u00a0vitro","volume":"6","author":"Gao","year":"2012","journal-title":"ACS Nano"},{"key":"10.1016\/j.resmic.2017.05.002_bib21","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1146\/annurev.biophys.093008.131348","article-title":"Chromatin dynamics","volume":"39","author":"H\u00fcbner","year":"2010","journal-title":"Annu Rev Biophys"},{"key":"10.1016\/j.resmic.2017.05.002_bib22","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1146\/annurev.cb.08.110192.000435","article-title":"ABC transporters: from microorganisms to man","volume":"8","author":"Higgins","year":"1992","journal-title":"Annu Rev Cell Biol"},{"key":"10.1016\/j.resmic.2017.05.002_bib23","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1038\/nature05630","article-title":"Multiple molecular mechanisms for multidrug resistance transporters","volume":"446","author":"Higgins","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.resmic.2017.05.002_bib24","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1089\/hum.2008.188","article-title":"Highly efficient multicistronic lentiviral vectors with peptide 2A sequences","volume":"20","author":"Ibrahimi","year":"2009","journal-title":"Hum Gene Ther"},{"key":"10.1016\/j.resmic.2017.05.002_bib25","doi-asserted-by":"crossref","first-page":"11910","DOI":"10.1039\/c3nr03515h","article-title":"A\u00a0new near infrared photosensitizing nanoplatform containing blue-emitting up-conversion nanoparticles and hypocrellin A for photodynamic therapy of cancer cells","volume":"5","author":"Jin","year":"2013","journal-title":"Nanoscale"},{"key":"10.1016\/j.resmic.2017.05.002_bib26","doi-asserted-by":"crossref","first-page":"W272","DOI":"10.1093\/nar\/gkw398","article-title":"CHOPCHOP v2: a web tool for the next generation of CRISPR genome engineering","volume":"44","author":"Labun","year":"2016","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.resmic.2017.05.002_bib27","doi-asserted-by":"crossref","first-page":"15007","DOI":"10.1038\/celldisc.2015.7","article-title":"Efficient genome editing in filamentous fungus Trichoderma reesei using the CRISPR\/Cas9 system","volume":"1","author":"Liu","year":"2015","journal-title":"Cell Discov"},{"key":"10.1016\/j.resmic.2017.05.002_bib28","doi-asserted-by":"crossref","first-page":"12649","DOI":"10.1073\/pnas.91.26.12649","article-title":"Tagged mutations at the Tox1 locus of Cochliobolus heterostrophus by restriction enzyme-mediated integration","volume":"91","author":"Lu","year":"1994","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.resmic.2017.05.002_bib29","doi-asserted-by":"crossref","first-page":"3002","DOI":"10.1073\/pnas.1420024112","article-title":"Multicolor CRISPR labeling of chromosomal loci in human cells","volume":"112","author":"Ma","year":"2015","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.resmic.2017.05.002_bib30","first-page":"34","article-title":"Multiplexed labeling of genomic loci with dCas9 and engineered sgRNAs using CRISPRainbow","author":"Ma","year":"2016","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.resmic.2017.05.002_bib31","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/s40694-015-0015-1","article-title":"Efficient gene editing in Neurospora crassa with CRISPR technology","volume":"2","author":"Matsu-ura","year":"2015","journal-title":"Fungal Biol Biotechnol"},{"key":"10.1016\/j.resmic.2017.05.002_bib32","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1039\/C6NP00006A","article-title":"Structural and mechanistic diversity of multidrug transporters","volume":"33","author":"Mousa","year":"2016","journal-title":"Nat Prod Rep"},{"key":"10.1016\/j.resmic.2017.05.002_bib33","doi-asserted-by":"crossref","first-page":"e0133085","DOI":"10.1371\/journal.pone.0133085","article-title":"A\u00a0CRISPR\u2013Cas9 system for genetic engineering of filamentous fungi","volume":"10","author":"N\u00f8dvig","year":"2015","journal-title":"PLoS ONE"},{"key":"10.1016\/j.resmic.2017.05.002_bib34","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/MMBR.62.1.1-34.1998","article-title":"Major facilitator superfamily","volume":"62","author":"Pao","year":"1998","journal-title":"Microbiol Mol Biol Rev"},{"key":"10.1016\/j.resmic.2017.05.002_bib35","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1021\/acssynbio.6b00082","article-title":"CRISPR\/Cas9 based genome editing of Penicillium chrysogenum","volume":"5","author":"Pohl","year":"2016","journal-title":"ACS Synth Biol"},{"key":"10.1016\/j.resmic.2017.05.002_bib36","doi-asserted-by":"crossref","first-page":"2281","DOI":"10.1038\/nprot.2013.143","article-title":"Genome engineering using the CRISPR\u2013Cas9 system","volume":"8","author":"Ran","year":"2013","journal-title":"Nat Protoc"},{"key":"10.1016\/j.resmic.2017.05.002_bib37","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/nbt.2842","article-title":"CRISPR\u2013Cas systems for editing, regulating and targeting genomes","volume":"32","author":"Sander","year":"2014","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.resmic.2017.05.002_bib38","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.fgb.2015.09.001","article-title":"Genome editing in Ustilago maydis using the CRISPR\u2013Cas system","volume":"89","author":"Schuster","year":"2016","journal-title":"Fungal Genet Biol"},{"key":"10.1016\/j.resmic.2017.05.002_bib39","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1089\/ars.2007.1957","article-title":"Redox regulation of cell survival","volume":"10","author":"Trachootham","year":"2008","journal-title":"Antioxid Redox Signal"},{"key":"10.1016\/j.resmic.2017.05.002_bib40","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1021\/acssynbio.6b00203","article-title":"Functional reconstitution of a fungal natural product gene cluster by advanced genome editing","volume":"6","author":"Weber","year":"2017","journal-title":"ACS Synth Biol"},{"key":"10.1016\/j.resmic.2017.05.002_bib41","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1007\/s10529-016-2113-4","article-title":"A\u00a0novel major facilitator superfamily transporter in Penicillium digitatum (PdMFS2) is required for prochloraz resistance, conidiation and full virulence","volume":"38","author":"Wu","year":"2016","journal-title":"Biotechnol Lett"},{"key":"10.1016\/j.resmic.2017.05.002_bib42","doi-asserted-by":"crossref","first-page":"e00011","DOI":"10.1128\/genomeA.00011-14","article-title":"Whole-genome shotgun assembly and analysis of the genome of Shiraia sp. strain Slf14, a novel endophytic fungus producing huperzine A and hypocrellin A","volume":"2","author":"Yang","year":"2014","journal-title":"Genome Announc"},{"key":"10.1016\/j.resmic.2017.05.002_bib43","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.procbio.2012.12.011","article-title":"Purification and characterization of a new laccase from Shiraia sp. SUPER-H168","volume":"48","author":"Yang","year":"2013","journal-title":"Process Biochem"},{"key":"10.1016\/j.resmic.2017.05.002_bib44","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.fgb.2015.12.007","article-title":"Highly efficient CRISPR mutagenesis by microhomology-mediated end joining in Aspergillus fumigatus","volume":"86","author":"Zhang","year":"2016","journal-title":"Fungal Genet Biol"}],"container-title":["Research in Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0923250817300955?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0923250817300955?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T05:13:56Z","timestamp":1760332436000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0923250817300955"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":44,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2017,9]]}},"alternative-id":["S0923250817300955"],"URL":"https:\/\/doi.org\/10.1016\/j.resmic.2017.05.002","relation":{},"ISSN":["0923-2508"],"issn-type":[{"value":"0923-2508","type":"print"}],"subject":[],"published":{"date-parts":[[2017,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characterization of a major facilitator superfamily transporter in Shiraia bambusicola","name":"articletitle","label":"Article Title"},{"value":"Research in Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.resmic.2017.05.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Institut Pasteur. Published by Elsevier Masson SAS.","name":"copyright","label":"Copyright"}]}}