{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T23:22:54Z","timestamp":1768778574800,"version":"3.49.0"},"reference-count":41,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Research in Microbiology"],"published-print":{"date-parts":[[2023,5]]},"DOI":"10.1016\/j.resmic.2023.104042","type":"journal-article","created":{"date-parts":[[2023,2,3]],"date-time":"2023-02-03T20:49:31Z","timestamp":1675457371000},"page":"104042","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Effect of acidic conditions on the growth and expression of two virulence genes of Listeria monocytogenes serotype 4b"],"prefix":"10.1016","volume":"174","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1947-8296","authenticated-orcid":false,"given":"Irene","family":"Mart\u00edn","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1088-1545","authenticated-orcid":false,"given":"Juan J.","family":"C\u00f3rdoba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alicia","family":"Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.resmic.2023.104042_bib1","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.fshw.2017.06.002","article-title":"Prevalence and methodologies for detection, characterization and subtyping of Listeria monocytogenes and L.\u00a0ivanovii in foods and environmental sources","volume":"6","author":"Chen","year":"2017","journal-title":"Food Sci Hum Wellness"},{"key":"10.1016\/j.resmic.2023.104042_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodcont.2020.107540","article-title":"Listeria monocytogenes dissemination in farming and primary production: sources, shedding and control measures","volume":"120","author":"Rodriguez","year":"2021","journal-title":"Food Control"},{"key":"10.1016\/j.resmic.2023.104042_bib3","article-title":"The European union one health 2020 zoonoses report","volume":"19","author":"ECDC","year":"2021","journal-title":"EFSA J"},{"key":"10.1016\/j.resmic.2023.104042_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijfoodmicro.2011.01.005","article-title":"Review - persistence of Listeria monocytogenes in food industry equipment and premises","author":"Carpentier","year":"2011","journal-title":"Int J Food Microbiol"},{"key":"10.1016\/j.resmic.2023.104042_bib5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fmicb.2018.02215","article-title":"Occurrence, antibiotic resistance, and population diversity of Listeria monocytogenes isolated from fresh aquatic products in China","volume":"9","author":"Chen","year":"2018","journal-title":"Front Microbiol"},{"key":"10.1016\/j.resmic.2023.104042_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijfoodmicro.2013.09.016","article-title":"Strain variability of the behavior of foodborne bacterial pathogens: a review","author":"Lianou","year":"2013","journal-title":"Int J Food Microbiol"},{"key":"10.1016\/j.resmic.2023.104042_bib7","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.foodres.2014.10.031","article-title":"Listeria monocytogenes in cheese and the dairy environment remains a food safety challenge: the role of stress responses","volume":"67","author":"Melo","year":"2015","journal-title":"Food Res Int"},{"key":"10.1016\/j.resmic.2023.104042_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/pathogens9070528","article-title":"Listeria monocytogenes virulence, antimicrobial resistance and environmental persistence: a review","volume":"9","author":"Matereke","year":"2020","journal-title":"Pathogens"},{"key":"10.1016\/j.resmic.2023.104042_bib9","series-title":"Mol. Food microbiol","first-page":"169","article-title":"Molecular mechanisms of Listeria monocytogenes. Stress responses","author":"Al\u00eda","year":"2021"},{"key":"10.1016\/j.resmic.2023.104042_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fmicb.2018.02700","article-title":"Resistance of Listeria monocytogenes to stress conditions encountered in food and food processing environments","volume":"9","author":"Bucur","year":"2018","journal-title":"Front Microbiol"},{"key":"10.1016\/j.resmic.2023.104042_bib11","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.ijfoodmicro.2013.05.001","article-title":"Filament formation by foodborne bacteria under sublethal stress","volume":"165","author":"Jones","year":"2013","journal-title":"Int J Food Microbiol"},{"key":"10.1016\/j.resmic.2023.104042_bib12","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.ijfoodmicro.2009.03.022","article-title":"Influence of acid stress on survival, expression of virulence genes and invasion capacity into Caco-2 cells of Listeria monocytogenes strains of different origins","volume":"134","author":"Werbrouck","year":"2009","journal-title":"Int J Food Microbiol"},{"key":"10.1016\/j.resmic.2023.104042_bib13","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1089\/fpd.2008.0243","article-title":"Gene transcription and virulence potential of Listeria monocytogenes strains after exposure to acidic and NaCl stress","volume":"6","author":"Olesen","year":"2009","journal-title":"Foodborne Pathog Dis"},{"key":"10.1016\/j.resmic.2023.104042_bib14","doi-asserted-by":"crossref","first-page":"4836","DOI":"10.1128\/AEM.00315-10","article-title":"Transcriptomic and phenotypic responses of Listeria monocytogenes strains possessing different growth efficiencies under acidic conditions","volume":"76","author":"Bowman","year":"2010","journal-title":"Appl Environ Microbiol"},{"key":"10.1016\/j.resmic.2023.104042_bib15","doi-asserted-by":"crossref","first-page":"5197","DOI":"10.1128\/AEM.03058-05","article-title":"\u03c3B activation under environmental and energy stress conditions in Listeria monocytogenes","volume":"72","author":"Chaturongakul","year":"2006","journal-title":"Appl Environ Microbiol"},{"key":"10.1016\/j.resmic.2023.104042_bib16","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1016\/0092-8674(91)90009-N","article-title":"Entry of L.\u00a0monocytogenes into cells is mediated by internalin, a repeat protein reminiscent of surface antigens from gram-positive cocci","volume":"65","author":"Gaillard","year":"1991","journal-title":"Cell"},{"key":"10.1016\/j.resmic.2023.104042_bib17","doi-asserted-by":"crossref","DOI":"10.1111\/cmi.13186","article-title":"Listeria monocytogenes, a model in infection biology","volume":"22","author":"Lecuit","year":"2020","journal-title":"Cell Microbiol"},{"key":"10.1016\/j.resmic.2023.104042_bib18","doi-asserted-by":"crossref","first-page":"3843","DOI":"10.1099\/mic.0.27257-0","article-title":"\u03c3B-dependent gene induction and expression in Listeria monocytogenes during osmotic and acid stress conditions simulating the intestinal environment","volume":"150","author":"Sue","year":"2004","journal-title":"Microbiology"},{"key":"10.1016\/j.resmic.2023.104042_bib19","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1089\/fpd.2019.2730","article-title":"Acid tolerance response of Listeria monocytogenes in various external pHs with different concentrations of lactic acid","volume":"17","author":"Liu","year":"2020","journal-title":"Foodborne Pathog Dis"},{"key":"10.1016\/j.resmic.2023.104042_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.fm.2019.103367","article-title":"Development of a multiplex real-time PCR to differentiate the four major Listeria monocytogenes serotypes in isolates from meat processing plants","volume":"87","author":"Al\u00eda","year":"2020","journal-title":"Food Microbiol"},{"key":"10.1016\/j.resmic.2023.104042_bib21","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1128\/AEM.70.3.1366-1377.2004","article-title":"Quantitative Detection of Listeria monocytogenes and Listeria innocua by Real-Time PCR: assessment of hly, iap, and lin02483 targets and AmpliFluor technology","volume":"70","author":"Rodr\u00edguez-L\u00e1zaro","year":"2004","journal-title":"Appl Environ Microbiol"},{"key":"10.1016\/j.resmic.2023.104042_bib22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/nar\/gks596","article-title":"Primer3-new capabilities and interfaces","volume":"40","author":"Untergasser","year":"2012","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.resmic.2023.104042_bib23","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1093\/bioinformatics\/btm091","article-title":"Enhancements and modifications of primer design program Primer","volume":"23","author":"Koressaar","year":"2007","journal-title":"Bioinformatics"},{"key":"10.1016\/j.resmic.2023.104042_bib24","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/978-1-4939-2365-6_3","article-title":"Design of primers and probes for quantitative real-time PCR methods","volume":"1275","author":"Rodriguez","year":"2015","journal-title":"Methods Mol Biol"},{"key":"10.1016\/j.resmic.2023.104042_bib25","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using Real-Time Quantitative PCR and the 2-\u0394\u0394CT method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.resmic.2023.104042_bib26","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.ijfoodmicro.2006.09.023","article-title":"Influence of pH, water activity and acetic acid concentration on Listeria monocytogenes at 7oC: data collection for the development of a growth\/no growth model","volume":"114","author":"Vermeulen","year":"2007","journal-title":"Int J Food Microbiol"},{"key":"10.1016\/j.resmic.2023.104042_bib27","series-title":"EURL Lm TECHNICAL GUIDANCE DOCUMENT on Challenge Tests and Durability Studies for Assessing Shelf-Life of Ready-To-Eat Foods Related to Listeria Monocytogenes","first-page":"60","year":"2021"},{"key":"10.1016\/j.resmic.2023.104042_bib28","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.ijfoodmicro.2012.07.027","article-title":"Adaptive acid tolerance response of Listeria monocytogenes strains under planktonic and immobilized growth conditions","volume":"159","author":"Skandamis","year":"2012","journal-title":"Int J Food Microbiol"},{"key":"10.1016\/j.resmic.2023.104042_bib29","doi-asserted-by":"crossref","first-page":"2754","DOI":"10.4315\/0362-028X-69.11.2754","article-title":"Assessment of environmental factors on Listeria monocytogenes Scott A gene expression by relative quantitative Taqman Real-Time reverse transcriptase PCR","volume":"69","author":"Hanna","year":"2006","journal-title":"J\u00a0Food Protect"},{"key":"10.1016\/j.resmic.2023.104042_bib30","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.ijfoodmicro.2011.06.019","article-title":"Quantification of ochratoxin A-producing molds in food products by SYBR Green and TaqMan real-time PCR methods","volume":"149","author":"Rodriguez","year":"2011","journal-title":"Int J Food Microbiol"},{"key":"10.1016\/j.resmic.2023.104042_bib31","doi-asserted-by":"crossref","first-page":"85","DOI":"10.4103\/2277-9175.127998","article-title":"Comparison of SYBR Green and TaqMan methods in quantitative real-time polymerase chain reaction analysis of four adenosine receptor subtypes","volume":"3","author":"Tajadini","year":"2014","journal-title":"Adv Biomed Res"},{"key":"10.1016\/j.resmic.2023.104042_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/IAI.00555-18","article-title":"Relative roles of Listeriolysin O, InlA, and InlB in Listeria monocytogenes uptake by host cells","volume":"86","author":"Phelps","year":"2018","journal-title":"Infect Immun"},{"key":"10.1016\/j.resmic.2023.104042_bib33","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1007\/s12161-014-0078-2","article-title":"Quantification of Penicillium nalgiovense on dry-cured sausage \u2018Salchich\u00f3n\u2019 using a SYBR Green-Based Real-Time PCR","volume":"8","author":"Cordero","year":"2015","journal-title":"Food Anal Methods"},{"key":"10.1016\/j.resmic.2023.104042_bib34","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.fm.2012.02.009","article-title":"Real-time PCR assays for detection and quantification of aflatoxin-producing molds in foods","volume":"31","author":"Rodr\u00edguez","year":"2012","journal-title":"Food Microbiol"},{"key":"10.1016\/j.resmic.2023.104042_bib35","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/microorganisms8091359","article-title":"Multiplex detection of Salmonella spp., E. Coli O157 and L. monocytogenes by qpcr melt curve analysis in spiked infant formula","volume":"8","author":"Azinheiro","year":"2020","journal-title":"Microorganisms"},{"key":"10.1016\/j.resmic.2023.104042_bib36","doi-asserted-by":"crossref","first-page":"4369","DOI":"10.1128\/IAI.70.8.4369-4378.2002","article-title":"Effect of acid adaptation on the fate of Listeria monocytogenes in THP-1 human macrophages activated by gamma interferon","volume":"70","author":"Conte","year":"2002","journal-title":"Infect Immun"},{"key":"10.1016\/j.resmic.2023.104042_bib37","first-page":"1","article-title":"Organic acid exposure enhances virulence in some Listeria monocytogenes strains using the Galleria mellonella infection model","volume":"12","author":"Li","year":"2021","journal-title":"Front Microbiol"},{"key":"10.1016\/j.resmic.2023.104042_bib38","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.meatsci.2019.04.017","article-title":"Effect of water activity, NaCl content and temperature on the growth and gene expression of Listeria monocytogenes in a dry-cured ham model system","volume":"155","author":"Al\u00eda","year":"2019","journal-title":"Meat Sci"},{"key":"10.1016\/j.resmic.2023.104042_bib39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2021\/6696856","article-title":"Indigenous microbiota to leverage traditional dry sausage production","volume":"2021","author":"Prpich","year":"2021","journal-title":"Int J Food Sci"},{"key":"10.1016\/j.resmic.2023.104042_bib40","first-page":"36","article-title":"Fermented foods: Past, present and future","author":"Ray","year":"2014","journal-title":"Microorg Ferment Tradit Foods"},{"key":"10.1016\/j.resmic.2023.104042_bib41","unstructured":"Commission E. Commission Regulation (EC) No 1441\/2007 of 5 December 2007 amending Regulation (EC) No 2073\/2005 on microbiological criteria for foodstuff. Off J Eur Communitites 2007."}],"container-title":["Research in Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0923250823000177?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0923250823000177?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T05:19:27Z","timestamp":1760332767000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0923250823000177"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":41,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["S0923250823000177"],"URL":"https:\/\/doi.org\/10.1016\/j.resmic.2023.104042","relation":{},"ISSN":["0923-2508"],"issn-type":[{"value":"0923-2508","type":"print"}],"subject":[],"published":{"date-parts":[[2023,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of acidic conditions on the growth and expression of two virulence genes of Listeria monocytogenes serotype 4b","name":"articletitle","label":"Article Title"},{"value":"Research in Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.resmic.2023.104042","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Institut Pasteur. Published by Elsevier Masson SAS.","name":"copyright","label":"Copyright"}],"article-number":"104042"}}