{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T11:12:34Z","timestamp":1762254754551,"version":"3.41.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"5-6","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Research in Microbiology"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.resmic.2024.104188","type":"journal-article","created":{"date-parts":[[2024,1,28]],"date-time":"2024-01-28T13:23:18Z","timestamp":1706448198000},"page":"104188","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["The murein endopeptidase MepA regulated by MtrAB and MprAB participate in cell wall homeostasis"],"prefix":"10.1016","volume":"175","author":[{"given":"Feng","family":"Peng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Zou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiuxia","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yankun","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianqi","family":"Nie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danni","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhonghu","family":"Bai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.resmic.2024.104188_bib1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1006934","article-title":"The mecillinam resistome reveals a role for peptidoglycan endopeptidases in stimulating cell wall synthesis in Escherichia coli","volume":"13","author":"Lai","year":"2017","journal-title":"PLoS Genet"},{"key":"10.1016\/j.resmic.2024.104188_bib2","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1007726","article-title":"A\u00a0central role for PBP2 in the activation of peptidoglycan polymerization by the bacterial cell elongation machinery","volume":"14","author":"Rohs","year":"2018","journal-title":"PLoS Genet"},{"key":"10.1016\/j.resmic.2024.104188_bib3","doi-asserted-by":"crossref","first-page":"7825","DOI":"10.1073\/pnas.1816893116","article-title":"Peptidoglycan hydrolase of an unusual cross-link cleavage specificity contributes to bacterial cell wall synthesis","volume":"116","author":"Chodisetti","year":"2019","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.resmic.2024.104188_bib4","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1111\/mmi.13258","article-title":"Identification of MltG as a potential terminase for peptidoglycan polymerization in bacteria","volume":"99","author":"Yunck","year":"2016","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.resmic.2024.104188_bib5","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.44912","article-title":"A\u00a0switch in surface polymer biogenesis triggers growth-phase-dependent and antibiotic-induced bacteriolysis","volume":"8","author":"Flores-Kim","year":"2019","journal-title":"Elife"},{"key":"10.1016\/j.resmic.2024.104188_bib6","doi-asserted-by":"crossref","first-page":"2647","DOI":"10.1038\/s41467-019-10586-2","article-title":"The hydrolase LpqI primes mycobacterial peptidoglycan recycling","volume":"10","author":"Moynihan","year":"2019","journal-title":"Nat Commun"},{"key":"10.1016\/j.resmic.2024.104188_bib7","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1003197","article-title":"Protein complexes and proteolytic activation of the cell wall hydrolase RipA regulate septal resolution in mycobacteria","volume":"9","author":"Chao","year":"2013","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.resmic.2024.104188_bib8","doi-asserted-by":"crossref","first-page":"609","DOI":"10.3390\/cells8060609","article-title":"The cell wall hydrolytic NlpC\/P60 endopeptidases in mycobacterial cytokinesis: a structural perspective","volume":"8","author":"Squeglia","year":"2019","journal-title":"Cells"},{"key":"10.1016\/j.resmic.2024.104188_bib9","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.3389\/fmicb.2019.01039","article-title":"The MarR-type regulator MalR is involved in stress-responsive cell envelope remodeling in Corynebacterium glutamicum","volume":"10","author":"H\u00fcnnefeld","year":"2019","journal-title":"Front Microbiol"},{"key":"10.1016\/j.resmic.2024.104188_bib10","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.00972-16","article-title":"Lcp1 is a phosphotransferase responsible for ligating arabinogalactan to peptidoglycan in Mycobacterium tuberculosis","volume":"7","author":"Harrison","year":"2016","journal-title":"mBio"},{"key":"10.1016\/j.resmic.2024.104188_bib11","doi-asserted-by":"crossref","first-page":"2533","DOI":"10.1002\/chem.201702973","article-title":"Chemistry of peptidoglycan in Mycobacterium tuberculosis life cycle: an off-the-wall balance of synthesis and degradation","volume":"24","author":"Squeglia","year":"2018","journal-title":"Chem--Eur J"},{"key":"10.1016\/j.resmic.2024.104188_bib12","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s11274-016-2060-1","article-title":"Updates on industrial production of amino acids using Corynebacterium glutamicum","volume":"32","author":"Wendisch","year":"2016","journal-title":"World J Microbiol Biotechnol"},{"key":"10.1016\/j.resmic.2024.104188_bib13","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1038\/s41589-018-0206-1","article-title":"Sequential assembly of the septal cell envelope prior to V snapping in Corynebacterium glutamicum","volume":"15","author":"Zhou","year":"2019","journal-title":"Nat Chem Biol"},{"key":"10.1016\/j.resmic.2024.104188_bib14","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1111\/mmi.14078","article-title":"Aspartate deficiency limits peptidoglycan synthesis and sensitizes cells to antibiotics targeting cell wall synthesis in Bacillus subtilis","volume":"109","author":"Zhao","year":"2018","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.resmic.2024.104188_bib15","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1038\/s41564-018-0345-x","article-title":"FtsW is a peptidoglycan polymerase that is functional only in complex with its cognate penicillin-binding protein","volume":"4","author":"Taguchi","year":"2019","journal-title":"Nature microbiology"},{"key":"10.1016\/j.resmic.2024.104188_bib16","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.mib.2017.01.006","article-title":"Robust peptidoglycan growth by dynamic and variable multi-protein complexes","volume":"36","author":"Pazos","year":"2017","journal-title":"Curr Opin Microbiol"},{"key":"10.1016\/j.resmic.2024.104188_bib17","doi-asserted-by":"crossref","first-page":"10956","DOI":"10.1073\/pnas.1507760112","article-title":"Regulated proteolysis of a cross-link\u2013specific peptidoglycan hydrolase contributes to bacterial morphogenesis","volume":"112","author":"Singh","year":"2015","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.resmic.2024.104188_bib18","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1111\/j.1365-2958.2004.04249.x","article-title":"Deletion of the genes encoding the MtrA\u2013MtrB two-component system of Corynebacterium glutamicum has a strong influence on cell morphology, antibiotics susceptibility and expression of genes involved in osmoprotection","volume":"54","author":"M\u00f6ker","year":"2004","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.resmic.2024.104188_bib19","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s10295-018-2091-8","article-title":"Triple deletion of clpC, porB, and mepA enhances production of small ubiquitin-like modifier-N-terminal pro-brain natriuretic peptide in Corynebacterium glutamicum","volume":"46","author":"Peng","year":"2019","journal-title":"J\u00a0Ind Microbiol Biotechnol"},{"key":"10.1016\/j.resmic.2024.104188_bib20","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1021\/bi0613776","article-title":"Mutational analysis of peptidoglycan amidase MepA","volume":"46","author":"Firczuk","year":"2007","journal-title":"Biochemistry"},{"key":"10.1016\/j.resmic.2024.104188_bib21","series-title":"Molecular genetics of mycobacteria","first-page":"209","article-title":"Two-component regulatory systems of mycobacteria","author":"Parish","year":"2014"},{"key":"10.1016\/j.resmic.2024.104188_bib22","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1099\/mic.0.27804-0","article-title":"Ethambutol, a cell wall inhibitor of Mycobacterium tuberculosis, elicits L-glutamate efflux of Corynebacterium glutamicum","volume":"151","author":"Radmacher","year":"2005","journal-title":"Microbiology"},{"key":"10.1016\/j.resmic.2024.104188_bib23","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/0378-1119(94)90324-7","article-title":"Small mobilizable multi-purpose cloning vectors derived from the Escherichia coli plasmids pK18 and pK19: selection of defined deletions in the chromosome of Corynebacterium glutamicum","volume":"145","author":"Sch\u00e4fer","year":"1994","journal-title":"Gene"},{"key":"10.1016\/j.resmic.2024.104188_bib24","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1023\/A:1008968419217","article-title":"Construction and application of new Corynebacterium glutamicum vectors","volume":"13","author":"Jakoby","year":"1999","journal-title":"Biotechnol Tech"},{"key":"10.1016\/j.resmic.2024.104188_bib25","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.carbpol.2013.04.028","article-title":"Structure and anti-inflammatory capacity of peptidoglycan from Lactobacillus acidophilus in RAW-264.7 cells","volume":"96","author":"Wu","year":"2013","journal-title":"Carbohydr Polym"},{"key":"10.1016\/j.resmic.2024.104188_bib26","doi-asserted-by":"crossref","first-page":"fny030","DOI":"10.1093\/femsle\/fny030","article-title":"Identification and validation of appropriate reference genes for qRT-PCR analysis in Corynebacterium glutamicum","volume":"365","author":"Wang","year":"2018","journal-title":"FEMS Microbiol Lett"},{"key":"10.1016\/j.resmic.2024.104188_bib27","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1007\/s00253-012-4060-x","article-title":"Two-component signal transduction in Corynebacterium glutamicum and other corynebacteria: on the way towards stimuli and targets","volume":"94","author":"Bott","year":"2012","journal-title":"Appl Microbiol Biotechnol"},{"key":"10.1016\/j.resmic.2024.104188_bib28","doi-asserted-by":"crossref","first-page":"2839","DOI":"10.3389\/fmicb.2018.02839","article-title":"MtrA response regulator controls cell division and cell wall metabolism and affects susceptibility of mycobacteria to the first line antituberculosis drugs","volume":"9","author":"Gorla","year":"2018","journal-title":"Front Microbiol"},{"issue":"7","key":"10.1016\/j.resmic.2024.104188_bib29","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.tim.2019.01.009","article-title":"Elucidating peptidoglycan structure: an analytical toolset","volume":"27","author":"Porf\u00edrio","year":"2019","journal-title":"Trends Microbiol"},{"key":"10.1016\/j.resmic.2024.104188_bib30","doi-asserted-by":"crossref","first-page":"43982","DOI":"10.1074\/jbc.M406735200","article-title":"Peptidoglycan amidase MepA is a LAS metallopeptidase","volume":"279","author":"Marcyjaniak","year":"2004","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.resmic.2024.104188_bib31","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1111\/j.1365-2958.2010.07383.x","article-title":"A\u00a0M23B family metallopeptidase of Helicobacter pylori required for cell shape, pole formation and virulence","volume":"78","author":"Bonis","year":"2010","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.resmic.2024.104188_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.jmb.2019.02.016","article-title":"The isoniazid paradigm of killing, resistance, and persistence in Mycobacterium tuberculosis","author":"Vilch\u00e8ze","year":"2019","journal-title":"J\u00a0Mol Biol"},{"key":"10.1016\/j.resmic.2024.104188_bib33","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.ijpharm.2018.12.076","article-title":"Mycobactericidal activity of some micro-encapsulated synthetic Host Defense Peptides (HDP) by expediting the permeation of antibiotic: a new paradigm of drug delivery for tuberculosis","volume":"558","author":"Sharma","year":"2019","journal-title":"Int J Pharm"},{"key":"10.1016\/j.resmic.2024.104188_bib34","doi-asserted-by":"crossref","first-page":"2134","DOI":"10.1128\/JB.188.6.2134-2143.2006","article-title":"MprAB is a stress-responsive two-component system that directly regulates expression of sigma factors SigB and SigE in Mycobacterium tuberculosis","volume":"188","author":"He","year":"2006","journal-title":"J\u00a0Bacteriol"}],"container-title":["Research in Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0923250824000123?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0923250824000123?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T17:57:02Z","timestamp":1751392622000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0923250824000123"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":34,"journal-issue":{"issue":"5-6","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["S0923250824000123"],"URL":"https:\/\/doi.org\/10.1016\/j.resmic.2024.104188","relation":{},"ISSN":["0923-2508"],"issn-type":[{"type":"print","value":"0923-2508"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The murein endopeptidase MepA regulated by MtrAB and MprAB participate in cell wall homeostasis","name":"articletitle","label":"Article Title"},{"value":"Research in Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.resmic.2024.104188","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Institut Pasteur. Published by Elsevier Masson SAS.","name":"copyright","label":"Copyright"}],"article-number":"104188"}}