{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T05:23:03Z","timestamp":1791091383768,"version":"4.1.0"},"reference-count":61,"publisher":"Elsevier BV","issue":"1-3","license":[{"start":{"date-parts":[[2005,11,1]],"date-time":"2005-11-01T00:00:00Z","timestamp":1130803200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,11,1]],"date-time":"2005-11-01T00:00:00Z","timestamp":1130803200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Physiology & Neurobiology"],"published-print":{"date-parts":[[2005,11]]},"DOI":"10.1016\/j.resp.2005.03.016","type":"journal-article","created":{"date-parts":[[2005,5,25]],"date-time":"2005-05-25T08:41:42Z","timestamp":1117010502000},"page":"181-190","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":68,"title":["Postnatal growth of the carotid body"],"prefix":"10.1016","volume":"149","author":[{"given":"Zun-Yi","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald E.","family":"Bisgard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.resp.2005.03.016_bib1","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1159\/000147039","article-title":"Immunohistochemical approach to the study of the cat carotid body","volume":"14","author":"Abramovici","year":"1991","journal-title":"Acta Anat."},{"key":"10.1016\/j.resp.2005.03.016_bib2","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.resp.2005.04.017","article-title":"Neurotransmitters in body chemoreceptor development","volume":"149","author":"Bairam","year":"2005","journal-title":"Respir. Physiol. Neurobiol."},{"key":"10.1016\/j.resp.2005.03.016_bib3","first-page":"L875","article-title":"Postnatal maturation of carotid body and type I cell chemoreception in the rat","volume":"276","author":"Bamford","year":"1999","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.resp.2005.03.016_bib4","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.resp.2005.04.003","article-title":"Developmental plasticity of the hypoxic ventilatory response after perinatal hyperoxia and hypoxia","volume":"149","author":"Bavis","year":"2005","journal-title":"Respir. Physiol. Neurobiol."},{"key":"10.1016\/j.resp.2005.03.016_bib5","doi-asserted-by":"crossref","first-page":"2919","DOI":"10.1101\/gad.841400","article-title":"Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system","volume":"14","author":"Bibel","year":"2000","journal-title":"Genes Dev."},{"key":"10.1016\/j.resp.2005.03.016_bib6","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1152\/japplphysiol.00985.2002","article-title":"Adult carotid chemoafferent responses to hypoxia after 1, 2, and 4 wk of postnatal hyperoxia","volume":"95","author":"Bisgard","year":"2003","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2005.03.016_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF00229549","article-title":"6-hydroxydopamine induces the loss of the dopaminergic phenotype in substantia nigra neurons of the rat. A possible mechanism for restoration of the nigrostriatal circuit mediated by glial cell line-derived neurotrophic factor","volume":"111","author":"Bowenkamp","year":"1996","journal-title":"Exp. Brain Res."},{"key":"10.1016\/j.resp.2005.03.016_bib8","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1523\/JNEUROSCI.19-06-02131.1999","article-title":"BDNF is a target-derived factor for arterial baroreceptor and chemoafferent primary sensory neurons","volume":"19","author":"Brady","year":"1999","journal-title":"J. Neurosci."},{"key":"10.1016\/j.resp.2005.03.016_bib9","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.1152\/jappl.1993.75.6.2383","article-title":"Postnatal maturation of carotid chemoreceptor responses to O2 and CO2 in the cat","volume":"75","author":"Carroll","year":"1993","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2005.03.016_bib10","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1152\/japplphysiol.00809.2002","article-title":"Developmental plasticity in respiratory control","volume":"94","author":"Carroll","year":"2003","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2005.03.016_bib11","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/0006-8993(88)90121-7","article-title":"The carotid body connections: a WGA-HRP study in the cat","volume":"455","author":"Claps","year":"1988","journal-title":"Brain Res."},{"key":"10.1016\/j.resp.2005.03.016_bib12","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/BF00707310","article-title":"The volume of the carotid body and periadventitial type I and type II cells in the carotid bifurcation region of the fetal cat and kitten","volume":"173","author":"Clarke","year":"1985","journal-title":"Anat. Embryol."},{"key":"10.1016\/j.resp.2005.03.016_bib13","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1159\/000146934","article-title":"Comparison of the size of the vascular compartment of the carotid body of the fetal, neonatal and adult cat","volume":"138","author":"Clarke","year":"1990","journal-title":"Acta Anatom."},{"key":"10.1016\/j.resp.2005.03.016_bib14","doi-asserted-by":"crossref","first-page":"2296","DOI":"10.1152\/jappl.2000.88.6.2296","article-title":"Developmental aspects of oxygen sensing by the carotid body","volume":"88","author":"Donnelly","year":"2000","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2005.03.016_bib15","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.resp.2005.02.006","article-title":"Developmental of carotid body\/petrosal ganglion response to hypoxia","volume":"149","author":"Donnelly","year":"2005","journal-title":"Respir. Physiol. Neurobiol."},{"key":"10.1016\/j.resp.2005.03.016_bib16","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1038\/381789a0","article-title":"GDNF signalling through the Ret receptor tyrosine kinase","volume":"381","author":"Durbec","year":"1996","journal-title":"Nature"},{"key":"10.1016\/j.resp.2005.03.016_bib17","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1111\/j.1469-7793.1998.519bn.x","article-title":"Chemoafferent degeneration and carotid body hypoplasia following chronic hyperoxia in newborn rats","volume":"509","author":"Erickson","year":"1998","journal-title":"J. Physiol."},{"key":"10.1016\/j.resp.2005.03.016_bib18","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1523\/JNEUROSCI.21-02-00581.2001","article-title":"Brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor are required simultaneously for survival of dopaminergic primary sensory neurons in vivo","volume":"21","author":"Erickson","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.resp.2005.03.016_bib19","first-page":"108","article-title":"Transmitter diversity in carotid body afferent neurons: dopaminergic and peptidergic phenotypes","volume":"572","author":"Finley","year":"1992","journal-title":"Neuroscience"},{"key":"10.1016\/j.resp.2005.03.016_bib20","doi-asserted-by":"crossref","first-page":"C106","DOI":"10.1152\/ajpcell.1984.246.1.C106","article-title":"Carotid body cell culture and selective growth of glomus cells","volume":"246","author":"Fishman","year":"1984","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.resp.2005.03.016_bib21","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1113\/jphysiol.2001.012908","article-title":"Life-long impairment of hypoxic phrenic responses in rats following 1 month of developmental hyperoxia","volume":"538","author":"Fuller","year":"2002","journal-title":"J. Physiol."},{"key":"10.1016\/j.resp.2005.03.016_bib22","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1152\/physrev.1994.74.4.829","article-title":"Carotid body chemoreceptors: From natural stimuli to sensory discharges","volume":"74","author":"Gonzalez","year":"1994","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.resp.2005.03.016_bib23","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/978-1-4615-2966-8_5","article-title":"Neuronal and neuroendocrine markers in the human carotid body in health and disease","volume":"337","author":"Habeck","year":"1993","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.resp.2005.03.016_bib24","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1111\/j.1365-2559.1990.tb00790.x","article-title":"Histopathology of the carotid bodies in neonates and infants","volume":"17","author":"Heath","year":"1990","journal-title":"Histopathology"},{"key":"10.1016\/j.resp.2005.03.016_bib25","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1007\/978-1-4615-2572-1_53","article-title":"Trophic regulation of carotid body afferent development","volume":"360","author":"Hertzberg","year":"1994","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.resp.2005.03.016_bib26","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1006\/dbio.1994.1358","article-title":"BDNF supports mammalian chemoafferent neurons in vitro and following peripheral target removal in vivo","volume":"166","author":"Hertzberg","year":"1994","journal-title":"Dev. Biol."},{"key":"10.1016\/j.resp.2005.03.016_bib27","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/0006-8993(93)91778-Q","article-title":"Presence and coexistence of putative neurotransmitters in carotid sinus baro- and chemoreceptor afferent neurons","volume":"611","author":"Ichikawa","year":"1993","journal-title":"Brain Res."},{"key":"10.1016\/j.resp.2005.03.016_bib28","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1177\/44.5.8627007","article-title":"Ultrastructural immunogold localization of vimentin and S-100 protein in guinea pig pars tuberalis","volume":"44","author":"Kameda","year":"1996","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.resp.2005.03.016_bib29","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1002\/aja.1001440303","article-title":"A light and electron microscopic study on the embryonic development of the rat carotid body","volume":"144","author":"Kondo","year":"1975","journal-title":"Am. J. Anat."},{"key":"10.1016\/j.resp.2005.03.016_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF00219262","article-title":"Innervation of the carotid body of the adult rat. A serial ultrathin section analysis","volume":"173","author":"Kondo","year":"1976","journal-title":"Cell Tiss. Res."},{"key":"10.1016\/j.resp.2005.03.016_bib31","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1007\/BF00210887","article-title":"Immunocytochemical study on the localization of neuron-specific enolase and S-100 protein in the carotid body of rats","volume":"227","author":"Kondo","year":"1982","journal-title":"Cell Tiss. Res."},{"key":"10.1016\/j.resp.2005.03.016_bib32","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/978-1-4615-5891-0_4","article-title":"Re-examination of the carotid body ultrastructure with special attention to intercellular membrane appositions","volume":"410","author":"Kondo","year":"1996","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.resp.2005.03.016_bib33","first-page":"13","article-title":"Plasticity and multiplicity in the mechanisms of oxygen sensing","volume":"475","author":"Lahiri","year":"2000","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.resp.2005.03.016_bib34","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/BF01217917","article-title":"A quantitative study of some ultrastructural features of the type I cells in the carotid bodies of rats living at a simulated altitude of 4300 metres","volume":"7","author":"Laidler","year":"1978","journal-title":"J. Neurocytol."},{"key":"10.1016\/j.resp.2005.03.016_bib35","series-title":"The Neural Crest","author":"Le Douarin","year":"1982"},{"key":"10.1016\/j.resp.2005.03.016_bib36","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1146\/annurev.neuro.24.1.87","article-title":"Glial control of neuronal development","volume":"24","author":"Lemke","year":"2001","journal-title":"Ann. Rev. Neurosci."},{"key":"10.1016\/j.resp.2005.03.016_bib37","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1126\/science.8493557","article-title":"GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons","volume":"260","author":"Lin","year":"1993","journal-title":"Science"},{"key":"10.1016\/j.resp.2005.03.016_bib38","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/BF01098781","article-title":"The innervation of glomus cells, ganglion cells and blood vessels in the rat carotid body: a quantitative ultrastructural study","volume":"4","author":"McDonald","year":"1975","journal-title":"J. Neurocytol."},{"key":"10.1016\/j.resp.2005.03.016_bib39","series-title":"Regulation of Breathing","first-page":"105","article-title":"Peripheral chemoreceptors: structure-function relationships of carotid body","author":"McDonald","year":"1981"},{"key":"10.1016\/j.resp.2005.03.016_bib40","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1007\/BF01159380","article-title":"Morphology of the rat carotid sinus nerve. I. Course, connections, dimensions and ultrastructure","volume":"12","author":"McDonald","year":"1983","journal-title":"J. Neurocytol."},{"key":"10.1016\/j.resp.2005.03.016_bib41","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1007\/BF01159381","article-title":"Morphology of the rat carotid sinus nerve. II. Number and size of axons","volume":"12","author":"McDonald","year":"1983","journal-title":"J. Neurocytol."},{"key":"10.1016\/j.resp.2005.03.016_bib42","first-page":"211","article-title":"Quantitative studies of the vasculature of the carotid body in fetal and newborn sheep","volume":"15","author":"Moore","year":"1991","journal-title":"J. Dev. Physiol."},{"key":"10.1016\/j.resp.2005.03.016_bib43","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/s004410050688","article-title":"Cellular expression of GDNF mRNA suggests multiple functions inside and outside the nervous system","volume":"286","author":"Nosrat","year":"1996","journal-title":"Cell Tiss. Res."},{"key":"10.1016\/j.resp.2005.03.016_bib44","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1002\/jemt.10199","article-title":"Carotid body chemoreceptors in dissociated cell culture","volume":"59","author":"Nurse","year":"2002","journal-title":"Micros. Res. Tech."},{"key":"10.1016\/j.resp.2005.03.016_bib45","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1159\/000146213","article-title":"Quantitative studies of rat carotid body type I cells","volume":"126","author":"Pallot","year":"1986","journal-title":"Acta Anat."},{"key":"10.1016\/j.resp.2005.03.016_bib46","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-3-642-71857-1_1","article-title":"The mammalian carotid body","volume":"102","author":"Pallot","year":"1987","journal-title":"Adv. Anat. Embryol. Cell. Biol."},{"key":"10.1016\/j.resp.2005.03.016_bib47","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/BF00303435","article-title":"Demonstration of the neural crest origin of type I (APUD) cells in the avian carotid body, using a cytochemical marker system","volume":"34","author":"Pearse","year":"1973","journal-title":"Histochemie"},{"key":"10.1016\/j.resp.2005.03.016_bib48","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0034-5687(00)00160-2","article-title":"Cellular mechanisms of oxygen sensing at the carotid body: heme proteins and ion channels","volume":"122","author":"Prabhakar","year":"2000","journal-title":"Respir. Physiol."},{"key":"10.1016\/j.resp.2005.03.016_bib49","first-page":"217","article-title":"Oxidative stress in the systemic and cellular responses to intermittent hypoxia","volume":"385","author":"Prabhakar","year":"2004","journal-title":"Bio. Chem."},{"key":"10.1016\/j.resp.2005.03.016_bib50","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1113\/jphysiol.2003.049445","article-title":"Ventilatory responses and carotid body function in adult rats perinatally exposed to hyperoxia","volume":"554","author":"Prieto-Lloret","year":"2004","journal-title":"J. Physiol."},{"key":"10.1016\/j.resp.2005.03.016_bib51","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/S0896-6273(00)80938-1","article-title":"Abnormal cerebellar development and foliation in BDNF-\/- mice reveals a role for neurotrophins in CNS patterning","volume":"19","author":"Schwartz","year":"1997","journal-title":"Neuron"},{"key":"10.1016\/j.resp.2005.03.016_bib52","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/978-1-4615-2572-1_19","article-title":"Culturing carotid body cells of adult cats","volume":"360","author":"Shirahata","year":"1994","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.resp.2005.03.016_bib53","first-page":"L645","article-title":"Chronic hypoxia abolished the postnatal increase in carotid body type I cell sensitivity to hypoxia","volume":"277","author":"Sterni","year":"1999","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.resp.2005.03.016_bib54","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1007\/BF01148589","article-title":"Distribution of sympathetic nerve endings within the rabbit carotid body: a histochemical and ultrastructural study","volume":"13","author":"Verna","year":"1984","journal-title":"J. Neurocytol."},{"key":"10.1016\/j.resp.2005.03.016_bib55","series-title":"The Carotid Body Chemoreceptors","first-page":"1","article-title":"The mammalian carotid body: morphological data","author":"Verna","year":"1997"},{"key":"10.1016\/j.resp.2005.03.016_bib56","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1007\/BF00698781","article-title":"A quantitative electron microscopic study of the effect of glucocorticoids in vivo on the early postnatal differentiation of paraneuronal cells in the carotid body and the adrenal medulla of the rat","volume":"174","author":"von Dalnok","year":"1986","journal-title":"Anat. Embryol."},{"key":"10.1016\/j.resp.2005.03.016_bib57","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/BF02741377","article-title":"GDNF: a novel factor with therapeutic potential for neurodegenerative disorders","volume":"19","author":"Walton","year":"1999","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.resp.2005.03.016_bib58","first-page":"168","article-title":"Chronic hypoxia-induced morphological and neurochemical changes in the carotid body","volume":"59","author":"Wang","year":"2002","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.resp.2005.03.016_bib59","first-page":"14","article-title":"Postnatal hyperoxia impairs carotid body development in rats (Abstract)","volume":"826","author":"Wang","year":"2003","journal-title":"Soc. Neurosci."},{"key":"10.1016\/j.resp.2005.03.016_bib60","first-page":"15","article-title":"Postnatal hypoxia enhances carotid body type I cell proliferation in rats (Abstract)","volume":"940","author":"Wang","year":"2004","journal-title":"Soc. Neurosci."},{"key":"10.1016\/j.resp.2005.03.016_bib61","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1111\/j.1469-7793.1999.493ae.x","article-title":"Resetting and postnatal maturation of oxygen chemosensitivity in rat carotid chemoreceptor cells","volume":"514","author":"Wasicko","year":"1999","journal-title":"J. Physiol."}],"container-title":["Respiratory Physiology & Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569904805000881?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569904805000881?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T22:11:24Z","timestamp":1761603084000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1569904805000881"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,11]]},"references-count":61,"journal-issue":{"issue":"1-3","published-print":{"date-parts":[[2005,11]]}},"alternative-id":["S1569904805000881"],"URL":"https:\/\/doi.org\/10.1016\/j.resp.2005.03.016","relation":{},"ISSN":["1569-9048"],"issn-type":[{"value":"1569-9048","type":"print"}],"subject":[],"published":{"date-parts":[[2005,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Postnatal growth of the carotid body","name":"articletitle","label":"Article Title"},{"value":"Respiratory Physiology & Neurobiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.resp.2005.03.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}