{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T22:18:09Z","timestamp":1761603489476,"version":"build-2065373602"},"reference-count":45,"publisher":"Elsevier BV","issue":"2-3","license":[{"start":{"date-parts":[[2006,4,1]],"date-time":"2006-04-01T00:00:00Z","timestamp":1143849600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,4,1]],"date-time":"2006-04-01T00:00:00Z","timestamp":1143849600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Physiology & Neurobiology"],"published-print":{"date-parts":[[2006,4]]},"DOI":"10.1016\/j.resp.2005.11.009","type":"journal-article","created":{"date-parts":[[2005,12,29]],"date-time":"2005-12-29T07:13:07Z","timestamp":1135840387000},"page":"96-108","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Jack Reeves and his science"],"prefix":"10.1016","volume":"151","author":[{"given":"Lorna G.","family":"Moore","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert F.","family":"Grover","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.resp.2005.11.009_bib1","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1152\/jappl.1967.23.6.849","article-title":"Reduction of stroke volume during exercise in man following ascent to 3100m altitude","volume":"23","author":"Alexander","year":"1967","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib2","doi-asserted-by":"crossref","first-page":"1966","DOI":"10.1152\/jappl.1998.85.5.1966","article-title":"Women at altitude: changes in carbohydrate metabolism at 4300m elevation and across the menstrual cycle","volume":"85","author":"Braun","year":"1998","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib3","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1152\/jappl.2000.88.1.246","article-title":"Women at altitude: carbohydrate utilization during exercise at 4300m","volume":"88","author":"Braun","year":"2000","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib4","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1152\/jappl.2001.91.2.623","article-title":"Women at altitude: short-term exposure to hypoxia and\/or alpha(1)-adrenergic blockade reduces insulin sensitivity","volume":"91","author":"Braun","year":"2001","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib5","first-page":"85","article-title":"Are arterial, muscle and working limb lactate exchange data obtained on men at altitude consistent with the hypothesis of an intracellular lactate shuttle?","volume":"474","author":"Brooks","year":"1999","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.resp.2005.11.009_bib6","doi-asserted-by":"crossref","first-page":"142","DOI":"10.3181\/00379727-164-40837","article-title":"Embryo-transplanted calves: the pulmonary hypertensive trait is genetically transmited","volume":"164","author":"Cruz","year":"1980","journal-title":"Proc. Soc. Exp. Biol. Med."},{"key":"10.1016\/j.resp.2005.11.009_bib7","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1152\/jappl.2001.91.1.100","article-title":"Gender alters impact of hypobaric hypoxia on adductor pollicis muscle performance","volume":"91","author":"Fulco","year":"2001","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib8","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1152\/jappl.1976.41.6.832","article-title":"Alterations in the coronary circulation of man following ascent to 3100m altitude","volume":"41","author":"Grover","year":"1976","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib9","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1161\/01.RES.38.5.391","article-title":"Maintained stroke volume but impaired arterial O2 ation in man at high altitude with supplemental CO2","volume":"38","author":"Grover","year":"1976","journal-title":"Circ. Res."},{"key":"10.1016\/j.resp.2005.11.009_bib10","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1007\/s004210050331","article-title":"\u03b2-adrenergic blockade does not prevent polycythemia or decrease in plasma volume in men at 4300m altitude","volume":"77","author":"Grover","year":"1998","journal-title":"Eur. J. Appl. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib11","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1152\/jappl.1987.63.2.531","article-title":"Operation Everest II: preservation of cardiac function at great altitude","volume":"63","author":"Groves","year":"1987","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib12","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1159\/000194501","article-title":"Fluid retention and relative hypoventilation in acute mountain sickness","volume":"43","author":"Hackett","year":"1982","journal-title":"Respiration"},{"key":"10.1016\/j.resp.2005.11.009_bib13","first-page":"374","article-title":"Control of breathing in Sherpas at low and high altitude","volume":"49","author":"Hackett","year":"1980","journal-title":"J. Appl. Physiol. Respir. Environ. Exercise Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib14","first-page":"602","article-title":"Hypocapnia and sustained hypoxia blunt ventilation on arrival at high altitude","volume":"56","author":"Huang","year":"1984","journal-title":"J. Appl. Physiol. Respir. Environ. Exercise Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib15","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/0034-5687(84)90085-9","article-title":"Increased metabolism contributes to increased resting ventilation at high altitude","volume":"57","author":"Huang","year":"1984","journal-title":"Respir. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib16","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1164\/arrd.1978.118.4.659","article-title":"Excessive polycythemia of high altitude: Role of ventilatory drive and lung disease","volume":"118","author":"Kryger","year":"1978","journal-title":"Am. Rev. Respir. Disease"},{"key":"10.1016\/j.resp.2005.11.009_bib17","doi-asserted-by":"crossref","unstructured":"Leon-Velarde, F., Maggiorini, M., Reeves, J., Aldashev, A., Asmus, I., Bernardi, L., Ge, R.-L., Hackett, P., Kobayashi, T., Moore, L., Penaloza, D., Richalet, J.-P., Roach, R., Wu, T., Vargas, E., Zubieta-Castillo, G., Zubieta-Calleja G. 2005. Consensus Statement on Chronic and Sub-Acute High Altitude Diseases [Position Paper]. High Alt. Med. Biol. 6, 147\u2013158.","DOI":"10.1089\/ham.2005.6.147"},{"key":"10.1016\/j.resp.2005.11.009_bib18","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1001\/archpedi.1957.02060040668009","article-title":"Studies of babies born at high altitude","volume":"93","author":"Lichty","year":"1957","journal-title":"Am. J. Diseases Children"},{"key":"10.1016\/j.resp.2005.11.009_bib19","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1152\/jappl.2000.88.1.272","article-title":"Women at altitude: energy requirement at 4300m","volume":"88","author":"Mawson","year":"2000","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib20","first-page":"E419","article-title":"Arterial catecholamine responses during exercise with acute and chronic high altitude exposure","volume":"261","author":"Mazzeo","year":"1991","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib21","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1152\/jappl.1994.76.2.610","article-title":"Beta-adrenergic blockade does not prevent the lactate response to exercise after acclimatization to high altitude","volume":"76","author":"Mazzeo","year":"1994","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib22","first-page":"R201","article-title":"Acclimatization to high altitude increase muscle sympathetic activity both at rest and during exercise","volume":"269","author":"Mazzeo","year":"1995","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib23","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1152\/jappl.2001.90.1.121","article-title":"Catecholamine responses to alpha-adrenergic blockade during exercise in women acutely exposed to altitude","volume":"90","author":"Mazzeo","year":"2001","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib24","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1016\/0026-0495(94)90215-1","article-title":"Sympathetic response during 21 days at high altitude (4,300m) as determined by urinary and arterial catecholamines","volume":"43","author":"Mazzeo","year":"1994","journal-title":"Metab. Clin. Exp."},{"key":"10.1016\/j.resp.2005.11.009_bib25","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1080\/00039896.1977.10667251","article-title":"Fetal growth retardation and increased infant mortality at high altitude","volume":"32","author":"McCullough","year":"1977","journal-title":"Arch. Environ. Health"},{"key":"10.1016\/j.resp.2005.11.009_bib26","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.1152\/jappl.1986.61.5.1935","article-title":"Propranolol does not impair exercise O2 uptake in normal men at high altitude","volume":"61","author":"Moore","year":"1986","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib27","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.1152\/jappl.2001.91.4.1791","article-title":"Women at altitude: ventilatory acclimatization at 4300m","volume":"91","author":"Muza","year":"2001","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib28","series-title":"Hypoxia and Molecular Medicine","article-title":"Sympathetics and hypoxia: A brief overview","author":"Reeves","year":"1993"},{"key":"10.1016\/j.resp.2005.11.009_bib29","doi-asserted-by":"crossref","unstructured":"Reeves, J, Groves, B.M., Sutton, J.R., Wagner, P.D., Cymerman, A., Malconian, M., Rock, P., Young, P., Houston, C., 1987. OEII: preservation of cardiac function at extreme altitude. J. Appl. Physiol. 63, 531\u2013539.","DOI":"10.1152\/jappl.1987.63.2.531"},{"key":"10.1016\/j.resp.2005.11.009_bib30","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1089\/1527029041352090","article-title":"Chronic mountain sickness: recent studies of the relationship between hemoglobin concentration and O2 transport","volume":"5","author":"Reeves","year":"2004","journal-title":"High Alt. Med. Biol."},{"key":"10.1016\/j.resp.2005.11.009_bib31","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1152\/jappl.1961.16.2.283","article-title":"The cardiac output response to standing and treadmill walking","volume":"16","author":"Reeves","year":"1961","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib32","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1152\/jappl.1967.22.3.546","article-title":"Regulation of ventilation during exercise at 10,200ft in athletes born at low altitude","volume":"22","author":"Reeves","year":"1967","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib33","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1152\/jappl.1961.16.2.276","article-title":"Cardiac output in normal resting man","volume":"16","author":"Reeves","year":"1961","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib34","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1152\/jappl.1961.16.2.279","article-title":"Circulatory changes in man during mild supine exercise","volume":"16","author":"Reeves","year":"1961","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib35","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1152\/jappl.1993.75.3.1117","article-title":"Sea-level PCO2 relates to ventilatory acclimatization at 4300m","volume":"75","author":"Reeves","year":"1993","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib36","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1152\/jappl.1985.59.3.909","article-title":"Headache at high altitude is not related to internal carotid arterial blood velocity","volume":"59","author":"Reeves","year":"1985","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib37","doi-asserted-by":"crossref","first-page":"2579","DOI":"10.1152\/jappl.2001.91.6.2579","article-title":"Erythropoiesis in women during 11 days at 4300m is not affected by menstrual cycle phase","volume":"91","author":"Reeves","year":"2001","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib38","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.1152\/jappl.1996.81.4.1762","article-title":"Acclimatization to 4300m altitude decreases reliance on fat as a substrate","volume":"81","author":"Roberts","year":"1996","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib39","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1056\/NEJM197712082972309","article-title":"High-altitude pulmonary edema in the children and young adults of Leadville, Colorado","volume":"297","author":"Scoggin","year":"1977","journal-title":"New England J. Med."},{"key":"10.1016\/j.resp.2005.11.009_bib40","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0034-5687(90)90015-Q","article-title":"Greater maximal O2 uptakes and vital capacities in Tibetan than Han residents of Lhasa","volume":"79","author":"Sun","year":"1990","journal-title":"Respir. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib41","first-page":"A784","article-title":"Cardiac output response during acclimatization to high altitude in women","volume":"13","author":"Tamhane","year":"1999","journal-title":"FASEB"},{"key":"10.1016\/j.resp.2005.11.009_bib42","series-title":"Attitudes on Altitude.","first-page":"59","article-title":"Major breathing in miners: Mabel Purefoy Fitzgerald, an intrepid scientist, visits Colorado's high mines","author":"Torrance","year":"2001"},{"key":"10.1016\/j.resp.2005.11.009_bib43","first-page":"10","article-title":"New ideas on limitations to V\u02d9O2max","volume":"28","author":"Wagner","year":"2000","journal-title":"Exerc. Sport. Sci. Rev."},{"key":"10.1016\/j.resp.2005.11.009_bib44","doi-asserted-by":"crossref","first-page":"H2636","DOI":"10.1152\/ajpheart.2001.281.6.H2636","article-title":"Women at altitude: forearm hemodynamics during acclimatization to 4,300m with alpha1-adrenergic blockade","volume":"281","author":"Zamudio","year":"2001","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.resp.2005.11.009_bib45","doi-asserted-by":"crossref","first-page":"1968","DOI":"10.1152\/jappl.1993.75.5.1968","article-title":"Autonomic regulation of heart rate response to exercise in Tibetan and Han residents of Lhasa (3658m)","volume":"75","author":"Zhuang","year":"1993","journal-title":"J. Appl. Physiol."}],"container-title":["Respiratory Physiology & Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569904805002776?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569904805002776?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T22:11:46Z","timestamp":1761603106000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1569904805002776"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,4]]},"references-count":45,"journal-issue":{"issue":"2-3","published-print":{"date-parts":[[2006,4]]}},"alternative-id":["S1569904805002776"],"URL":"https:\/\/doi.org\/10.1016\/j.resp.2005.11.009","relation":{},"ISSN":["1569-9048"],"issn-type":[{"type":"print","value":"1569-9048"}],"subject":[],"published":{"date-parts":[[2006,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Jack Reeves and his science","name":"articletitle","label":"Article Title"},{"value":"Respiratory Physiology & Neurobiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.resp.2005.11.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}