{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T20:31:37Z","timestamp":1790800297610,"version":"4.1.0"},"reference-count":52,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2007,11,1]],"date-time":"2007-11-01T00:00:00Z","timestamp":1193875200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,11,1]],"date-time":"2007-11-01T00:00:00Z","timestamp":1193875200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Physiology & Neurobiology"],"published-print":{"date-parts":[[2007,11]]},"DOI":"10.1016\/j.resp.2007.06.008","type":"journal-article","created":{"date-parts":[[2007,6,23]],"date-time":"2007-06-23T07:08:37Z","timestamp":1182582517000},"page":"163-170","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":68,"title":["The alkaline tide goes out and the nitrogen stays in after feeding in the dogfish shark, Squalus acanthias"],"prefix":"10.1016","volume":"159","author":[{"given":"Chris M.","family":"Wood","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carol","family":"Bucking","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Fitzpatrick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunita","family":"Nadella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.resp.2007.06.008_bib1","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.1242\/jeb.200.17.2337","article-title":"The interactive effects of feeding and exercise on oxygen consumption, swimming performance and protein usage in juvenile rainbow trout","volume":"200","author":"Alsop","year":"1997","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.resp.2007.06.008_bib2","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/S0305-0491(97)00272-1","article-title":"Jaws: the inside story. The metabolism of elasmobranch fishes","volume":"B118","author":"Ballantyne","year":"1997","journal-title":"Comp. Biochem. Physiol."},{"key":"10.1016\/j.resp.2007.06.008_bib3","first-page":"335","article-title":"Contributions to the chemistry of the urine. On the variations in the alkaline and earthy phosphates in the healthy state, and on the alkalescence of the urine from fixed alkalies","volume":"135","author":"Bence Jones","year":"1845","journal-title":"Phil. Trans. R. Soc. Lond."},{"key":"10.1016\/j.resp.2007.06.008_bib4","first-page":"403","article-title":"Appendix: physicochemical parameters for use in fish respiratory physiology","volume":"vol. 10A","author":"Boutilier","year":"1984"},{"key":"10.1016\/j.resp.2007.06.008_bib5","first-page":"280","article-title":"Physiological energetics","volume":"vol. 8","author":"Brett","year":"1979"},{"key":"10.1016\/j.resp.2007.06.008_bib6","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1152\/physrev.1933.13.3.372","article-title":"The acid output of the kidney and the so-called alkaline tide","volume":"13","author":"Brunton","year":"1933","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.resp.2007.06.008_bib7","first-page":"R185","article-title":"Effects of feeding on metabolism, gas transport, and acid\u2013base balance in the bullfrog Rana catesbeiana","author":"Busk","year":"2000","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.resp.2007.06.008_bib8","series-title":"The ABC of acid\u2013base chemistry","author":"Davenport","year":"1974"},{"key":"10.1016\/j.resp.2007.06.008_bib9","first-page":"R16","article-title":"Active urea transport and an unusual basolateral membrane composition in the gills of a marine elasmobranch","volume":"280","author":"Fines","year":"2001","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.resp.2007.06.008_bib10","first-page":"R1138","article-title":"Branchial membrane-associated carbonic anhydrase activity maintains CO2 excretion in severely anemic dogfish","volume":"286","author":"Gilmour","year":"2004","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.resp.2007.06.008_bib11","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1242\/jeb.200.1.173","article-title":"Extracellular carbonic anhydrase and an acid\u2013base disequilibrium in the blood of the dogfish Squalus acanthias","volume":"200","author":"Gilmour","year":"1997","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.resp.2007.06.008_bib12","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1086\/322157","article-title":"Extracellular carbonic anhydrase in dogfish. Squalus acanthias: a role in CO2 excretion","volume":"74","author":"Gilmour","year":"2001","journal-title":"Physiol. Biochem. Zool."},{"key":"10.1016\/j.resp.2007.06.008_bib13","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.1242\/jeb.02345","article-title":"Intestinal anion exchange in marine fish osmoregulation","volume":"209","author":"Grosell","year":"2006","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.resp.2007.06.008_bib14","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/BF00389169","article-title":"Hypo-osmotic regulation coupled with reduced metabolic urea in the dogfish Poroderma africanum: an analysis of serum osmolality, chloride and urea","volume":"23","author":"Haywood","year":"1973","journal-title":"Mar. Biol."},{"key":"10.1016\/j.resp.2007.06.008_bib15","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1086\/515878","article-title":"Extracellular carbonic anhydrase activity and carbonic anhydrase inhibitors in the circulatory system of fish","volume":"70","author":"Henry","year":"1997","journal-title":"Physiol. Zool."},{"key":"10.1016\/j.resp.2007.06.008_bib16","first-page":"1182","article-title":"Urine pH and carbonic anhydrase activity in the marine dogfish","volume":"222","author":"Hodler","year":"1955","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.resp.2007.06.008_bib17","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1016\/0043-1354(84)90230-6","article-title":"An optimal manual procedure for ammonia analysis in natural water by the indophenol blue method","volume":"18","author":"Ivancic","year":"1984","journal-title":"Water Res."},{"key":"10.1016\/j.resp.2007.06.008_bib18","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1111\/j.1095-8649.1983.tb02946.x","article-title":"A short review and critique of methodology used in fish growth and nutrition studies","volume":"23","author":"Jobling","year":"1983","journal-title":"J. Fish Biol."},{"key":"10.1016\/j.resp.2007.06.008_bib19","series-title":"Fish Bioenergetics","author":"Jobling","year":"1994"},{"key":"10.1016\/j.resp.2007.06.008_bib20","first-page":"2067","article-title":"Food and feeding of spiny dogfish (Squalus acanthias) in British Columbia waters","volume":"34","author":"Jones","year":"1977","journal-title":"J. Fish. Res. Bd. Canada"},{"key":"10.1016\/j.resp.2007.06.008_bib21","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1086\/501060","article-title":"The dogfish shark (Squalus acanthias) activates both hepatic and extra-hepatic ornithine urea cycle enzyme activities for nitrogen conservation after feeding","volume":"79","author":"Kajimura","year":"2006","journal-title":"Physiol. Biochem. Zool."},{"key":"10.1016\/j.resp.2007.06.008_bib22","first-page":"R581","article-title":"Renal ammoniagenesis and acid excretion in the dogfish. Squalus acanthias","volume":"245","author":"King","year":"1983","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.resp.2007.06.008_bib23","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1002\/jez.1402070108","article-title":"Alanine biosynthesis during starvation in skeletal muscle of the spiny dogfish, Squalus acanthias","volume":"207","author":"Leech","year":"1979","journal-title":"J. Exp. Zool."},{"key":"10.1016\/j.resp.2007.06.008_bib24","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/0034-5687(66)90025-9","article-title":"Respiratory function in the elasmobranch Squalus suckleyi","volume":"1","author":"Lenfant","year":"1966","journal-title":"Respir. Physiol."},{"key":"10.1016\/j.resp.2007.06.008_bib25","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1242\/jeb.93.1.101","article-title":"Branchial and renal acid and ion fluxes in the rainbow trout, Salmo gairdneri, at low environmental pH","volume":"93","author":"McDonald","year":"1981","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.resp.2007.06.008_bib26","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1242\/jeb.98.1.403","article-title":"H+ excretion in the marine teleost, Parophrys vetulus","volume":"98","author":"McDonald","year":"1982","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.resp.2007.06.008_bib27","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.aquaculture.2006.10.022","article-title":"Aspects of respiratory physiology and energetics in rainbow trout (Oncorhynchus mykiss) families with different size-at-age and condition factor","volume":"263","author":"McKenzie","year":"2007","journal-title":"Aquaculture"},{"key":"10.1016\/j.resp.2007.06.008_bib28","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1097\/00004836-200207000-00003","article-title":"The alkaline tide phenomenon","volume":"35","author":"Niv","year":"2002","journal-title":"J. Clin. Gastroenterol."},{"key":"10.1016\/j.resp.2007.06.008_bib29","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S1095-6433(97)00400-5","article-title":"Urea and water permeability in dogfish gills (Squalus acanthias)","volume":"119","author":"P\u00e4rt","year":"1998","journal-title":"Comp. Biochem. Physiol. A"},{"key":"10.1016\/j.resp.2007.06.008_bib30","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/0009-8981(80)90407-6","article-title":"Improvements in the determination of urea using diacetyl monoxime: methods with and without deproteinization","volume":"107","author":"Rahmatullah","year":"1980","journal-title":"Clin. Chem. Acta"},{"key":"10.1016\/j.resp.2007.06.008_bib31","first-page":"238","article-title":"A contribution to urology, embracing observations on the diurnal variations, in the acidity of the urine, chiefly in relation to food","volume":"15","author":"Roberts","year":"1859","journal-title":"Lit. Phil. Soc."},{"key":"10.1016\/j.resp.2007.06.008_bib32","doi-asserted-by":"crossref","first-page":"305","DOI":"10.3109\/00365516509077055","article-title":"The metabolic alkalosis following aspiration of gastric acid secretion","volume":"17","author":"Rune","year":"1965","journal-title":"Scand. J. Clin. Lab. Invest."},{"key":"10.1016\/j.resp.2007.06.008_bib33","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1136\/gut.7.4.344","article-title":"Comparison of the rates of gastric acid secretion in man after ingestion of food and after maximal stimulation with histamine","volume":"7","author":"Rune","year":"1966","journal-title":"Gut"},{"key":"10.1016\/j.resp.2007.06.008_bib34","first-page":"341","article-title":"Does specific dynamic action (SDA) regulate return of appetite in the lesser spotted dogfish, Scyliorhinus canicula?","volume":"45","author":"Sims","year":"1994","journal-title":"J. Fish. Biol."},{"key":"10.1016\/j.resp.2007.06.008_bib35","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1152\/ajplegacy.1931.98.2.296","article-title":"The absorption and secretion of water and salts by the elasmobranch fishes. II. Marine elasmobranchs","volume":"98","author":"Smith","year":"1931","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.resp.2007.06.008_bib36","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/j.1469-185X.1936.tb00497.x","article-title":"The retention and physiological role of urea in the elasmobranchii","volume":"11","author":"Smith","year":"1936","journal-title":"Biol. Rev."},{"key":"10.1016\/j.resp.2007.06.008_bib37","doi-asserted-by":"crossref","first-page":"2939","DOI":"10.1242\/jeb.02342","article-title":"Feeding and osmoregulation: dual function of the marine teleost intestine","volume":"209","author":"Taylor","year":"2006","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.resp.2007.06.008_bib38","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1007\/s00360-007-0158-3","article-title":"Post-prandial acid\u2013base balance and ion regulation in freshwater and seawater-acclimated European flounder, Platichthys flesus","volume":"177","author":"Taylor","year":"2007","journal-title":"J. Comp. Physiol. B."},{"key":"10.1016\/j.resp.2007.06.008_bib39","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1242\/jeb.01382","article-title":"Regulation of branchial V-H+-ATPase. Na+\/K+-ATPase and NHE2 in response to acid and base infusions in the Pacific spiny dogfish (Squalus acanthias)","volume":"208","author":"Tresguerres","year":"2005","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.resp.2007.06.008_bib40","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1242\/jeb.02059","article-title":"Microtubule-dependent relocation of branchial V-H+-ATPase to the basolateral membrane in the Pacific spiny dogfish (Squalus acanthias): a role in base secretion","volume":"209","author":"Tresguerres","year":"2006","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.resp.2007.06.008_bib41","first-page":"2012","article-title":"V-H+-ATPase translocation during blood alkalosis in dogfish gills: interaction with carbonic anhydrase and involvement in the post-feeding alkaline tide","volume":"292","author":"Tresguerres","year":"2007","journal-title":"Am. J. Physiol. R."},{"key":"10.1016\/j.resp.2007.06.008_bib42","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/0300-9629(78)90185-8","article-title":"Anaerobic production of carbon dioxide and ammonia by goldfish Carassius auratus (L.)","volume":"A59","author":"van den Thillart","year":"1978","journal-title":"Comp. Biochem. Physiol."},{"key":"10.1016\/j.resp.2007.06.008_bib43","first-page":"328","article-title":"Preservation of urinary postprandial alkaline tide despite inhibition of gastric acid secretion","volume":"74","author":"Vaziri","year":"1980","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.resp.2007.06.008_bib44","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/S1095-6433(00)00334-2","article-title":"The respiratory consequences of feeding in amphibians and reptiles","volume":"128","author":"Wang","year":"2001","journal-title":"Comp. Biochem. Physiol. A"},{"key":"10.1016\/j.resp.2007.06.008_bib45","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S0166-445X(99)00063-6","article-title":"Bioaccumulation and distribution of silver in four marine teleosts and two marine elasmobranchs: influence of exposure duration, concentration, and salinity","volume":"49","author":"Webb","year":"2000","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.resp.2007.06.008_bib46","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1023\/A:1007890000123","article-title":"Branchial carbonic anhydrase is present in the dogfish, Squalus acanthias","volume":"22","author":"Wilson","year":"2000","journal-title":"Fish Physiol. Biochem."},{"key":"10.1016\/j.resp.2007.06.008_bib47","first-page":"201","article-title":"The influence of feeding, exercise, and temperature on nitrogen metabolism and excretion","volume":"vol. 20","author":"Wood","year":"2001"},{"key":"10.1016\/j.resp.2007.06.008_bib48","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1242\/jeb.189.1.13","article-title":"Urea production, acid\u2013base regulation and their interactions in the Lake Magadi tilapia, a unique teleost adapted to a highly alkaline environment","volume":"189","author":"Wood","year":"1994","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.resp.2007.06.008_bib49","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/0034-5687(94)90080-9","article-title":"HCO3\u2212 dehydration by the blood of an elasmobranch in the absence of a Haldane effect","volume":"98","author":"Wood","year":"1994","journal-title":"Respir. Physiol."},{"key":"10.1016\/j.resp.2007.06.008_bib50","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1242\/jeb.198.7.1545","article-title":"Ammonia and urea metabolism in relation to gill function and acid\u2013base balance in a marine elasmobranch, the spiny dogfish (Squalus acanthias)","volume":"198","author":"Wood","year":"1995","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.resp.2007.06.008_bib51","doi-asserted-by":"crossref","first-page":"2693","DOI":"10.1242\/jeb.01678","article-title":"Alkaline tide and nitrogen conservation after feeding in the elasmobranch Squalus acanthius","volume":"208","author":"Wood","year":"2005","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.resp.2007.06.008_bib52","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1242\/jeb.02736","article-title":"Osmoregulation, ionoregulation, and acid\u2013base regulation by the gastrointestinal tract after feeding in the dogfish shark","volume":"210","author":"Wood","year":"2007","journal-title":"J. Exp. Biol."}],"container-title":["Respiratory Physiology & Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569904807001929?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569904807001929?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T22:14:11Z","timestamp":1761603251000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1569904807001929"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,11]]},"references-count":52,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,11]]}},"alternative-id":["S1569904807001929"],"URL":"https:\/\/doi.org\/10.1016\/j.resp.2007.06.008","relation":{},"ISSN":["1569-9048"],"issn-type":[{"value":"1569-9048","type":"print"}],"subject":[],"published":{"date-parts":[[2007,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The alkaline tide goes out and the nitrogen stays in after feeding in the dogfish shark, Squalus acanthias","name":"articletitle","label":"Article Title"},{"value":"Respiratory Physiology & Neurobiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.resp.2007.06.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}