{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T18:51:14Z","timestamp":1791226274203,"version":"4.1.0"},"reference-count":83,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Physiology & Neurobiology"],"published-print":{"date-parts":[[2009,5]]},"DOI":"10.1016\/j.resp.2008.05.006","type":"journal-article","created":{"date-parts":[[2008,5,19]],"date-time":"2008-05-19T04:05:00Z","timestamp":1211169900000},"page":"26-35","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":82,"title":["Respiratory sensations evoked by activation of bronchopulmonary C-fibers"],"prefix":"10.1016","volume":"167","author":[{"given":"Lu-Yuan","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.resp.2008.05.006_bib1","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1007\/s004410051131","article-title":"Pulmonary intraepithelial vagal nodose afferent nerve terminals are confined to neuroepithelial bodies: an anterograde tracing and confocal microscopy study in adult rats","volume":"293","author":"Adriaensen","year":"1998","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.resp.2008.05.006_bib2","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1002\/cne.903190408","article-title":"Substance P-immunoreactive sensory axons in the rat respiratory tract: a quantitative study of their distribution and role in neurogenic inflammation","volume":"319","author":"Baluk","year":"1992","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.resp.2008.05.006_bib3","article-title":"Airway neuropeptides and asthma","volume":"vol. 49","author":"Barnes","year":"1991"},{"key":"10.1016\/j.resp.2008.05.006_bib4","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1152\/jappl.2001.91.4.1645","article-title":"Enhanced lung C-fiber responsiveness in sensitized adult guinea pigs exposed to chronic tobacco smoke","volume":"91","author":"Bergren","year":"2001","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2008.05.006_bib5","doi-asserted-by":"crossref","first-page":"393","DOI":"10.3181\/00379727-114-28687","article-title":"Evidence for a ventilation modifying reflex from the pulmonary circulation in man","volume":"114","author":"Bevan","year":"1963","journal-title":"Proc. Soc. Exp. Biol. Med."},{"key":"10.1016\/j.resp.2008.05.006_bib6","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1016\/S0140-6736(88)91668-6","article-title":"Unilateral facial pain in patients with lung cancer: a referred pain via the vagus?","volume":"1","author":"Bindoff","year":"1988","journal-title":"Lancet"},{"key":"10.1016\/j.resp.2008.05.006_bib7","series-title":"Advances in Vagal Afferent Neurobiology","first-page":"193","article-title":"Synaptic transmission in the nucleus tractus solitarius","author":"Bonham","year":"2005"},{"key":"10.1016\/j.resp.2008.05.006_bib8","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1152\/japplphysiol.00913.2004","article-title":"Intravenous adenosine and dyspnea in humans","volume":"98","author":"Burki","year":"2005","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2008.05.006_bib9","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.pupt.2007.02.004","article-title":"Effects of airway anesthesia on dyspnea and ventilatory response to intravenous injection of adenosine in healthy human subjects","volume":"21","author":"Burki","year":"2008","journal-title":"Pulm. Pharmacol. Ther."},{"key":"10.1016\/j.resp.2008.05.006_bib10","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1113\/jphysiol.2003.057885","article-title":"Identification of the tracheal and laryngeal afferent neurones mediating cough in anaesthetized guinea-pigs","volume":"557","author":"Canning","year":"2004","journal-title":"J. Physiol."},{"key":"10.1016\/j.resp.2008.05.006_bib11","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1164\/ajrccm.165.8.2108065","article-title":"Expression of tachykinins in nonnociceptive vagal afferent neurons during respiratory viral infection in guinea pigs","volume":"165","author":"Carr","year":"2002","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.resp.2008.05.006_bib12","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0034-5687(00)00206-1","article-title":"Ion channels in airway afferent neurons","volume":"125","author":"Carr","year":"2001","journal-title":"Respir. Physiol."},{"key":"10.1016\/j.resp.2008.05.006_bib13","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.resp.2005.11.003","article-title":"Plasticity of peripheral mechanisms of cough","volume":"152","author":"Carr","year":"2006","journal-title":"Respir. Physiol. Neurobiol."},{"key":"10.1016\/j.resp.2008.05.006_bib14","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1038\/39807","article-title":"The capsaicin receptor: a heat-activated ion channel in the pain pathway","volume":"389","author":"Caterina","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.resp.2008.05.006_bib15","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1164\/ajrccm\/140.1.137","article-title":"Sensitivity of the human cough reflex: effect of inflammatory mediators prostaglandin E2, bradykinin, and histamine","volume":"140","author":"Choudry","year":"1989","journal-title":"Am. Rev. Respir. Dis."},{"key":"10.1016\/j.resp.2008.05.006_bib16","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.pupt.2004.12.010","article-title":"Effect of 5-hydroxytryptamine on vagal C-fiber subtypes in guinea pig lungs","volume":"18","author":"Chuaychoo","year":"2005","journal-title":"Pulm. Pharmacol. Ther."},{"key":"10.1016\/j.resp.2008.05.006_bib17","series-title":"Krogh Centenary Symposium on Respiratiory Adaptions, Capillary Exchange and Reflex Mechanisms","first-page":"393","article-title":"Afferent vagal C-fibers in the dog lung: their discharge during spontaneous breathing and their stimulation by alloxan and pulmonary congestion","author":"Coleridge","year":"1977"},{"key":"10.1016\/j.resp.2008.05.006_bib18","series-title":"Handbook of Physiology, Section 3: The Respiratory System, Vol. II: Control of Breathing, Part I","first-page":"395","article-title":"Reflexes evoked from tracheobronchial tree and lungs","author":"Coleridge","year":"1986"},{"key":"10.1016\/j.resp.2008.05.006_bib19","first-page":"1","article-title":"Afferent vagal C fibre innervation of the lungs and airways and its functional significance","volume":"99","author":"Coleridge","year":"1984","journal-title":"Rev. Physiol. Biochem. Pharmacol."},{"key":"10.1016\/j.resp.2008.05.006_bib20","unstructured":"Davenport, P. Cortical and subcortical pathways in dyspnea. Respir. Physiol. Neurobiol., in press."},{"key":"10.1016\/j.resp.2008.05.006_bib21","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1164\/ajrccm\/136.1.184","article-title":"Extreme dyspnea from unilateral pulmonary venous obstruction. Demonstration of a vagal mechanism and relief by right vagotomy","volume":"136","author":"Davies","year":"1987","journal-title":"Am. Rev. Respir. Dis."},{"key":"10.1016\/j.resp.2008.05.006_bib22","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0034-5687(00)00223-1","article-title":"Role of vagal afferents in the reflex effects of capsaicin and lobeline in monkeys","volume":"125","author":"Deep","year":"2001","journal-title":"Respir. Physiol."},{"key":"10.1016\/j.resp.2008.05.006_bib23","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.pupt.2006.10.003","article-title":"Experimentally induced cough","volume":"20","author":"Dicpinigaitis","year":"2007","journal-title":"Pulm. Pharmacol. Ther."},{"key":"10.1016\/j.resp.2008.05.006_bib24","doi-asserted-by":"crossref","first-page":"725","DOI":"10.3181\/00379727-76-18608","article-title":"Blocking of tetraethylammonium on lobelin-induced thoracic pain","volume":"76","author":"Eckenhoff","year":"1951","journal-title":"Proc. Soc. Exp. Biol. Med."},{"key":"10.1016\/j.resp.2008.05.006_bib25","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1111\/j.1476-5381.1959.tb00960.x","article-title":"Pharmacological properties of phenyldiguanide and other amidine derivatives in relation to those of 5-hydroxytryptamine","volume":"14","author":"Fastier","year":"1959","journal-title":"Br. J. Pharmacol. Chemother."},{"issue":"Pt 1","key":"10.1016\/j.resp.2008.05.006_bib26","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.1469-7793.1998.289bi.x","article-title":"Absence of viscerosomatic inhibition with injections of lobeline designed to activate human pulmonary C fibres","volume":"511","author":"Gandevia","year":"1998","journal-title":"J. Physiol."},{"key":"10.1016\/j.resp.2008.05.006_bib27","doi-asserted-by":"crossref","first-page":"1985","DOI":"10.1152\/jn.00748.2002","article-title":"Ca2+ transient evoked by chemical stimulation is enhanced by PGE2 in vagal sensory neurons: role of cAMP\/PKA signaling pathway","volume":"89","author":"Gu","year":"2003","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.resp.2008.05.006_bib28","doi-asserted-by":"crossref","first-page":"L58","DOI":"10.1152\/ajplung.00517.2005","article-title":"Characterization of acid signaling in rat vagal pulmonary sensory neurons","volume":"291","author":"Gu","year":"2006","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"key":"10.1016\/j.resp.2008.05.006_bib29","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.resp.2007.11.006","article-title":"Expression of neuronal nicotinic acetylcholine receptors in rat vagal pulmonary sensory neurons","volume":"161","author":"Gu","year":"2008","journal-title":"Respir. Physiol. Neurobiol."},{"key":"10.1016\/j.resp.2008.05.006_bib30","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1093\/oxfordjournals.bmb.a071419","article-title":"Respiratory sensations in man","volume":"33","author":"Guz","year":"1977","journal-title":"Br. Med. Bull."},{"key":"10.1016\/j.resp.2008.05.006_bib31","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0034-5687(97)00050-9","article-title":"Brain, breathing and breathlessness","volume":"109","author":"Guz","year":"1997","journal-title":"Respir. Physiol."},{"key":"10.1016\/j.resp.2008.05.006_bib32","series-title":"Breathing: Hering-Breuer Centenary Symposium","first-page":"315","article-title":"Experimental results of vagal block in cardiopulmonary disease","author":"Guz","year":"1970"},{"key":"10.1016\/j.resp.2008.05.006_bib33","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1152\/physrev.1991.71.3.617","article-title":"Reflexes from the heart","volume":"71","author":"Hainsworth","year":"1991","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.resp.2008.05.006_bib34","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1164\/ajrccm\/145.5.1191","article-title":"Regional sensitivity of human airways to capsaicin-induced cough","volume":"145","author":"Hansson","year":"1992","journal-title":"Am. Rev. Respir. Dis."},{"key":"10.1016\/j.resp.2008.05.006_bib35","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0022-3565(25)23319-5","article-title":"Abuse liability and pharmacodynamic characteristics of intravenous and inhaled nicotine","volume":"234","author":"Henningfield","year":"1985","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.resp.2008.05.006_bib36","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1164\/ajrccm.162.2.9910059","article-title":"Prostaglandin E(2) enhances chemical and mechanical sensitivities of pulmonary C fibers in the rat","volume":"162","author":"Ho","year":"2000","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.resp.2008.05.006_bib37","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0034-5687(01)00241-9","article-title":"Sensitivity of vagal afferent endings to chemical irritants in the rat lung","volume":"127","author":"Ho","year":"2001","journal-title":"Respir. Physiol."},{"key":"10.1016\/j.resp.2008.05.006_bib38","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1152\/jappl.1998.85.4.1509","article-title":"Ozone enhances excitabilities of pulmonary C fibers to chemical and mechanical stimuli in anesthetized rats","volume":"85","author":"Ho","year":"1998","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2008.05.006_bib39","first-page":"1059","article-title":"Effect of ozone on bronchial reactivity in atopic and nonatopic subjects","volume":"120","author":"Holtzman","year":"1979","journal-title":"Am. Rev. Respir. Dis."},{"key":"10.1016\/j.resp.2008.05.006_bib40","first-page":"686","article-title":"Importance of airway inflammation for hyperresponsiveness induced by ozone","volume":"127","author":"Holtzman","year":"1983","journal-title":"Am. Rev. Respir. Dis."},{"issue":"Pt 1","key":"10.1016\/j.resp.2008.05.006_bib41","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/j.1469-7793.1998.109br.x","article-title":"Activation of pulmonary C fibres by adenosine in anaesthetized rats: role of adenosine A1 receptors","volume":"508","author":"Hong","year":"1998","journal-title":"J. Physiol."},{"key":"10.1016\/j.resp.2008.05.006_bib42","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1042\/cs0420163","article-title":"Search for evidence of lung chemoreflexes in man: study of respiratory and circulatory effects of phenyldiguanide and lobeline","volume":"42","author":"Jain","year":"1972","journal-title":"Clin. Sci."},{"key":"10.1016\/j.resp.2008.05.006_bib43","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0165-1838(82)90037-6","article-title":"Afferent and efferent components of the bronchial vagal branches in cats","volume":"5","author":"Jammes","year":"1982","journal-title":"J. Auton. Nerv. Syst."},{"key":"10.1016\/j.resp.2008.05.006_bib44","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1113\/jphysiol.1987.sp016869","article-title":"Behaviour of canine pulmonary vagal afferent receptors during sustained acute pulmonary venous pressure elevation","volume":"394","author":"Kappagoda","year":"1987","journal-title":"J. Physiol."},{"key":"10.1016\/j.resp.2008.05.006_bib45","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1006\/pupt.1999.0207","article-title":"Pharmacological regulation of the cough reflex\u2014from experimental models to antitussive effects in man","volume":"12","author":"Karlsson","year":"1999","journal-title":"Pulm. Pharmacol. Ther."},{"key":"10.1016\/j.resp.2008.05.006_bib46","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1113\/jphysiol.2002.022848","article-title":"Mechanisms of acid-induced activation of airway afferent nerve fibres in guinea-pig","volume":"543","author":"Kollarik","year":"2002","journal-title":"J. Physiol."},{"key":"10.1016\/j.resp.2008.05.006_bib47","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1159\/000235449","article-title":"Distribution of substance P-immunoreactive and calcitonin gene-related peptide-immunoreactive nerves in normal human lungs","volume":"95","author":"Komatsu","year":"1991","journal-title":"Int. Arch. Allergy Appl. Immunol."},{"key":"10.1016\/j.resp.2008.05.006_bib48","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1152\/jappl.1975.39.1.37","article-title":"Pulmonary afferent activity recorded from sympathetic nerves","volume":"39","author":"Kostreva","year":"1975","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2008.05.006_bib49","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/0034-5687(91)90093-X","article-title":"Mechanisms of cigarette smoke-induced stimulation of rapidly adapting receptors in canine lungs","volume":"83","author":"Kou","year":"1991","journal-title":"Respir. Physiol."},{"key":"10.1016\/j.resp.2008.05.006_bib50","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1152\/japplphysiol.00382.2002","article-title":"PGE(2) sensitizes cultured pulmonary vagal sensory neurons to chemical and electrical stimuli","volume":"93","author":"Kwong","year":"2002","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2008.05.006_bib51","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1113\/jphysiol.2004.078725","article-title":"Prostaglandin E2 potentiates a TTX-resistant sodium current in rat capsaicin-sensitive vagal pulmonary sensory neurones","volume":"564","author":"Kwong","year":"2005","journal-title":"J. Physiol."},{"key":"10.1016\/j.resp.2008.05.006_bib52","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1152\/jappl.1993.75.5.1955","article-title":"Nicotine is responsible for airway irritation evoked by cigarette smoke inhalation in men","volume":"75","author":"Lee","year":"1993","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2008.05.006_bib53","doi-asserted-by":"crossref","first-page":"2032","DOI":"10.1152\/jappl.1989.66.5.2032","article-title":"Stimulation of vagal pulmonary C-fibers by a single breath of cigarette smoke in dogs","volume":"66","author":"Lee","year":"1989","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2008.05.006_bib54","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1006\/pupt.2002.0338","article-title":"Hypersensitivity of bronchopulmonary C-fibers induced by airway mucosal inflammation: cellular mechanisms","volume":"15","author":"Lee","year":"2002","journal-title":"Pulm. Pharmacol. Ther."},{"key":"10.1016\/j.resp.2008.05.006_bib55","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0034-5687(00)00204-8","article-title":"Afferent properties and reflex functions of bronchopulmonary C-fibers","volume":"125","author":"Lee","year":"2001","journal-title":"Respir. Physiol."},{"key":"10.1016\/j.resp.2008.05.006_bib56","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.pupt.2004.09.002","article-title":"Mechanisms of chronic cough","volume":"17","author":"Lee","year":"2004","journal-title":"Pulm. Pharmacol. Ther."},{"key":"10.1016\/j.resp.2008.05.006_bib57","series-title":"Advances in Vagal Afferent Neurobiology","first-page":"279","article-title":"Brochopulmonary vagal sensory nerves","author":"Lee","year":"2005"},{"key":"10.1016\/j.resp.2008.05.006_bib58","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1152\/japplphysiol.00532.2005","article-title":"Stimulatory effect of CO2 on vagal bronchopulmonary C-fiber afferents during airway inflammation","volume":"99","author":"Lin","year":"2005","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2008.05.006_bib59","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1164\/rccm.200612-1856OC","article-title":"Representation of capsaicin-evoked urge-to-cough in the human brain using functional magnetic resonance imaging","volume":"176","author":"Mazzone","year":"2007","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.resp.2008.05.006_bib60","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1111\/j.1476-5381.1983.tb10040.x","article-title":"On the specificity and type of receptor involved in carotid body chemoreceptor activation by adenosine in the cat","volume":"80","author":"McQueen","year":"1983","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.resp.2008.05.006_bib61","first-page":"800","article-title":"The clinical physiology of the human bronchi II. The effect of vagus section upon pain of tracheobronchial origin","volume":"30","author":"Morton","year":"1951","journal-title":"Surgery"},{"key":"10.1016\/j.resp.2008.05.006_bib62","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.pupt.2004.09.028","article-title":"Mechanisms of acute cough","volume":"17","author":"Page","year":"2004","journal-title":"Pulm. Pharmacol. Ther."},{"key":"10.1016\/j.resp.2008.05.006_bib63","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1152\/physrev.1973.53.1.159","article-title":"Vagal sensory receptors and their reflex effects","volume":"53","author":"Paintal","year":"1973","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.resp.2008.05.006_bib64","first-page":"238","article-title":"Sensation from J receptors","volume":"10","author":"Paintal","year":"1995","journal-title":"News Physiol. Sci."},{"issue":"Pt 1","key":"10.1016\/j.resp.2008.05.006_bib65","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1113\/jphysiol.1995.sp020513","article-title":"Sensory origin of lobeline-induced sensations: a correlative study in man and cat","volume":"482","author":"Raj","year":"1995","journal-title":"J. Physiol."},{"key":"10.1016\/j.resp.2008.05.006_bib66","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/0002-9343(92)90784-9","article-title":"Adenosine and the treatment of supraventricular tachycardia","volume":"92","author":"Rankin","year":"1992","journal-title":"Am. J. Med."},{"key":"10.1016\/j.resp.2008.05.006_bib67","unstructured":"Ravi, K., Kappagoda, C.T. Rapidly adapting receptors in acute heart failure and their impact on dyspnea. Respir. Physiol. Neurobiol., in press."},{"key":"10.1016\/j.resp.2008.05.006_bib68","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0034-5687(96)00070-9","article-title":"Role of vagal lung C-fibres in the cardiorespiratory effects of capsaicin in monkeys","volume":"106","author":"Ravi","year":"1996","journal-title":"Respir. Physiol."},{"issue":"Pt 2","key":"10.1016\/j.resp.2008.05.006_bib69","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1113\/jphysiol.1996.sp021703","article-title":"Interganglionic segregation of distinct vagal afferent fibre phenotypes in guinea-pig airways","volume":"496","author":"Ricco","year":"1996","journal-title":"J. Physiol."},{"key":"10.1016\/j.resp.2008.05.006_bib70","doi-asserted-by":"crossref","first-page":"238","DOI":"10.3171\/jns.1993.79.2.0238","article-title":"Video-assisted endoscopic thoracic ganglionectomy","volume":"79","author":"Robertson","year":"1993","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.resp.2008.05.006_bib71","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1164\/ajrccm\/136.3.586","article-title":"Enhancement by parainfluenza 3 infection of contractile responses to substance P and capsaicin in airway smooth muscle from the guinea pig","volume":"136","author":"Saban","year":"1987","journal-title":"Am. Rev. Respir. Dis."},{"key":"10.1016\/j.resp.2008.05.006_bib72","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1152\/physrev.1982.62.2.531","article-title":"Information arising from the tracheobronchial tree of mammals","volume":"62","author":"Sant\u2019Ambrogio","year":"1982","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.resp.2008.05.006_bib73","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1136\/thx.51.3.335","article-title":"Airway sensory nerves: a burning issue in asthma?","volume":"51","author":"Spina","year":"1996","journal-title":"Thorax"},{"key":"10.1016\/j.resp.2008.05.006_bib74","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/0002-8703(66)90315-2","article-title":"Localization of lobeline-sensitive receptors in the pulmonary circulation in man","volume":"71","author":"Stern","year":"1966","journal-title":"Am. Heart J."},{"key":"10.1016\/j.resp.2008.05.006_bib75","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1164\/ajrccm\/145.6.1346","article-title":"Prostaglandin E2 inhalation increases the sensation of dyspnea during exercise","volume":"145","author":"Taguchi","year":"1992","journal-title":"Am. Rev. Respir. Dis."},{"key":"10.1016\/j.resp.2008.05.006_bib76","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1113\/jphysiol.2003.060079","article-title":"Subtypes of vagal afferent C-fibres in guinea-pig lungs","volume":"556","author":"Undem","year":"2004","journal-title":"J. Physiol."},{"key":"10.1016\/j.resp.2008.05.006_bib77","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0165-1838(93)90375-5","article-title":"Electrophysiological properties and chemosensitivity of guinea pig nodose ganglion neurons in vitro","volume":"44","author":"Undem","year":"1993","journal-title":"J. Auton. Nerv. Syst."},{"key":"10.1016\/j.resp.2008.05.006_bib78","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1016\/j.neuroscience.2006.04.073","article-title":"Immunohistochemical co-localization of transient receptor potential vanilloid (TRPV)1 and sensory neuropeptides in the guinea-pig respiratory system","volume":"141","author":"Watanabe","year":"2006","journal-title":"Neuroscience"},{"key":"10.1016\/j.resp.2008.05.006_bib79","series-title":"Lung Biology in Health and Disease. Regulation of Breathing","article-title":"Nerve receptors in the respiratory tree and lungs","author":"Widdicombe","year":"1981"},{"key":"10.1016\/j.resp.2008.05.006_bib80","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.resp.2006.04.001","article-title":"Cough and its regulation","volume":"152","author":"Widdicombe","year":"2006","journal-title":"Respir. Physiol. Neurobiol."},{"key":"10.1016\/j.resp.2008.05.006_bib81","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1042\/cs0710519","article-title":"Respiratory and cardiovascular effects of central and peripheral intravenous injections of capsaicin in man: evidence for pulmonary chemosensitivity","volume":"71","author":"Winning","year":"1986","journal-title":"Clin. Sci. (Lond.)"},{"key":"10.1016\/j.resp.2008.05.006_bib82","doi-asserted-by":"crossref","first-page":"L54","DOI":"10.1152\/ajplung.00182.2006","article-title":"Calcium transient evoked by nicotine in isolated rat vagal pulmonary sensory neurons","volume":"292","author":"Xu","year":"2007","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"key":"10.1016\/j.resp.2008.05.006_bib83","article-title":"Sensitizing effects of chronic exposure and acute inhalation of ovalbumin aerosol on pulmonary C-fibers in rats","author":"Zhang","year":"2008","journal-title":"J. Appl. Physiol."}],"container-title":["Respiratory Physiology & Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569904808001316?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569904808001316?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T22:20:27Z","timestamp":1761603627000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1569904808001316"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5]]},"references-count":83,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,5]]}},"alternative-id":["S1569904808001316"],"URL":"https:\/\/doi.org\/10.1016\/j.resp.2008.05.006","relation":{},"ISSN":["1569-9048"],"issn-type":[{"value":"1569-9048","type":"print"}],"subject":[],"published":{"date-parts":[[2009,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Respiratory sensations evoked by activation of bronchopulmonary C-fibers","name":"articletitle","label":"Article Title"},{"value":"Respiratory Physiology & Neurobiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.resp.2008.05.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}