{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T18:51:36Z","timestamp":1791226296184,"version":"4.1.0"},"reference-count":22,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2011,8,1]],"date-time":"2011-08-01T00:00:00Z","timestamp":1312156800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,8,1]],"date-time":"2011-08-01T00:00:00Z","timestamp":1312156800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Physiology & Neurobiology"],"published-print":{"date-parts":[[2011,8]]},"DOI":"10.1016\/j.resp.2011.05.013","type":"journal-article","created":{"date-parts":[[2011,5,22]],"date-time":"2011-05-22T16:18:31Z","timestamp":1306081111000},"page":"320-326","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Effects of different forms of dyspnoea on pain perception induced by cold-pressor test"],"prefix":"10.1016","volume":"177","author":[{"given":"Eiko","family":"Yashiro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natsuko","family":"Nozaki-Taguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiroh","family":"Isono","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Nishino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.resp.2011.05.013_bib0005","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1152\/jappl.1993.74.2.590","article-title":"Effects of naloxone on the sensation of dyspnoea during acute respiratory stress in normal adults","volume":"74","author":"Akiyama","year":"1993","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2011.05.013_bib0010","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0034-5687(89)90017-0","article-title":"\u201cAir hunger\u201d arising from increased PCO2 in mechanically ventilated quadriplegics","volume":"76","author":"Banzett","year":"1989","journal-title":"Respir. Physiol."},{"key":"10.1016\/j.resp.2011.05.013_bib0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0034-5687(90)90065-7","article-title":"\u2018Air hunger\u2019 from increased PCO2 persists after complete neuromuscular block in humans","volume":"81","author":"Banzett","year":"1990","journal-title":"Respir. Physiol."},{"key":"10.1016\/j.resp.2011.05.013_bib0020","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1152\/jn.00970.2006","article-title":"When it's hard to breathe, maybe pain doesn\u2019t matter. Focus on \u201cDyspnoea as a noxious sensation: inspiratory threshold loading may trigger diffuse noxious inhibitory controls in humans\u201d","volume":"97","author":"Banzett","year":"2007","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.resp.2011.05.013_bib0025","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.pain.2007.11.012","article-title":"A family-based investigation of cold pain tolerance","volume":"138","author":"Birklein","year":"2008","journal-title":"Pain"},{"key":"10.1016\/j.resp.2011.05.013_bib0030","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1113\/jphysiol.1987.sp016658","article-title":"Heterotopic activation of A delta and C fibres triggers inhibition of trigeminal and spinal convergent neurons in the rat","volume":"389","author":"Bouhassira","year":"1987","journal-title":"J. Physiol."},{"key":"10.1016\/j.resp.2011.05.013_bib0035","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/0304-3959(89)90126-7","article-title":"Human pain responsivity in a tonic pain model: psychological determinants","volume":"37","author":"Chen","year":"1989","journal-title":"Pain"},{"key":"10.1016\/j.resp.2011.05.013_bib0040","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/0006-8993(82)90718-1","article-title":"Pharmacological evidence for the involvement of serotonergic mechanisms in diffuse noxious inhibitory controls (DNIC)","volume":"236","author":"Chitour","year":"1982","journal-title":"Brain Res."},{"key":"10.1016\/j.resp.2011.05.013_bib0045","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/0006-8993(90)91416-E","article-title":"Hypercapnia depresses nociception: endogenous opioids implicated","volume":"514","author":"Gamble","year":"1990","journal-title":"Brain Res."},{"key":"10.1016\/j.resp.2011.05.013_bib0050","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1007\/BF00599245","article-title":"A selective suppression of human pain sensitivity by carbon dioxide: central mechanisms implicated","volume":"68","author":"Gr\u00f6nroos","year":"1994","journal-title":"Eur. J. Appl. Physiol. Occup. Physiol."},{"key":"10.1016\/j.resp.2011.05.013_bib0055","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1164\/ajrccm.162.5.9907096","article-title":"The perception of respiratory work and effort can be independent of the perception of air hunger","volume":"162","author":"Lansing","year":"2000","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.resp.2011.05.013_bib0060","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/0304-3959(79)90049-6","article-title":"Diffuse noxious inhibitory controls (DNIC). I. Effects on dorsal horn convergent neurones in the rat","volume":"6","author":"Le Bars","year":"1979","journal-title":"Pain"},{"key":"10.1016\/j.resp.2011.05.013_bib0065","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/0304-3959(79)90050-2","article-title":"Diffuse noxious inhibitory controls (DNIC). II. Lack of effect on non-convergent neurones, supraspinal involvement and theoretical implications","volume":"6","author":"Le Bars","year":"1979","journal-title":"Pain"},{"key":"10.1016\/j.resp.2011.05.013_bib0070","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0034-5687(00)00135-3","article-title":"Acute partial paralysis alters perceptions of air hunger, work and effort at constant PCO2 and VE","volume":"122","author":"Moosavi","year":"2000","journal-title":"Respir. Physiol."},{"key":"10.1016\/j.resp.2011.05.013_bib0075","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1152\/jn.00116.2006","article-title":"Dyspnoea as a noxious sensation: inspiratory threshold loading may trigger diffuse noxious inhibitory controls in humans","volume":"97","author":"Mor\u00e9lot-Panzini","year":"2007","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.resp.2011.05.013_bib0080","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1097\/00000542-199912000-00014","article-title":"Experimental pain augments experimental dyspnoea, but not vice versa in human volunteers","volume":"91","author":"Nishino","year":"1999","journal-title":"Anesthesiology"},{"key":"10.1016\/j.resp.2011.05.013_bib0085","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1097\/ALN.0b013e31818d8f43","article-title":"Sex differences in the effect of dyspnoea on thermal pain threshold in young healthy subjects","volume":"109","author":"Nishino","year":"2008","journal-title":"Anesthesiology"},{"key":"10.1016\/j.resp.2011.05.013_bib0090","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.pain.2009.11.024","article-title":"Comparison of pain and dyspnoea perceptual responses in healthy subjects","volume":"148","author":"Nishino","year":"2010","journal-title":"Pain"},{"key":"10.1016\/j.resp.2011.05.013_bib0095","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.resp.2009.01.010","article-title":"Mechanisms of activity-related dyspnoea in pulmonary diseases","volume":"167","author":"O\u2019Donnell","year":"2009","journal-title":"Respir. Physiol. Neurobiol."},{"key":"10.1016\/j.resp.2011.05.013_bib0100","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/0014-2999(93)90175-H","article-title":"Effects of dothiepin on nociceptive flexion reflex and diffuse noxious inhibitory controls in humans","volume":"243","author":"Sandrini","year":"1993","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.resp.2011.05.013_bib0105","first-page":"382","article-title":"Endorphins and the control of breathing. Ability of naloxone to restore flow-resistive load compensation in chronic obstructive pulmonary disease","volume":"123","author":"Santiago","year":"1981","journal-title":"Am. Rev. Respir. Dis."},{"key":"10.1016\/j.resp.2011.05.013_bib0110","first-page":"113","article-title":"The activation of bulbo-spinal controls by peripheral nociceptive inputs: diffuse noxious inhibitory controls","volume":"28","author":"Villanueva","year":"1995","journal-title":"Bio. Res."}],"container-title":["Respiratory Physiology & Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569904811001960?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569904811001960?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T22:23:57Z","timestamp":1761603837000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1569904811001960"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,8]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,8]]}},"alternative-id":["S1569904811001960"],"URL":"https:\/\/doi.org\/10.1016\/j.resp.2011.05.013","relation":{},"ISSN":["1569-9048"],"issn-type":[{"value":"1569-9048","type":"print"}],"subject":[],"published":{"date-parts":[[2011,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of different forms of dyspnoea on pain perception induced by cold-pressor test","name":"articletitle","label":"Article Title"},{"value":"Respiratory Physiology & Neurobiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.resp.2011.05.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}