{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T18:31:54Z","timestamp":1792089114295,"version":"4.4.0"},"reference-count":102,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Physiology &amp; Neurobiology"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1016\/j.resp.2012.05.013","type":"journal-article","created":{"date-parts":[[2012,5,22]],"date-time":"2012-05-22T05:00:26Z","timestamp":1337662826000},"page":"194-201","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":38,"title":["The carotid body in Sudden Infant Death Syndrome"],"prefix":"10.1016","volume":"185","author":[{"given":"Andrea","family":"Porzionato","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronica","family":"Macchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla","family":"Stecco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaele","family":"De Caro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.resp.2012.05.013_bib0005","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1152\/jappl.1984.57.5.1531","article-title":"Effect of a single breath of 100% oxygen on respiration in neonates during sleep","volume":"57","author":"Aizad","year":"1984","journal-title":"Journal of Applied Physiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0010","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1542\/peds.2006-1245","article-title":"Distinguishing sudden infant death syndrome from child abuse fatalities","volume":"118","author":"American Academy of Pediatrics","year":"2006","journal-title":"Pediatrics"},{"key":"10.1016\/j.resp.2012.05.013_bib0015","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.siny.2003.11.007","article-title":"Clinical correlates, natural history and outcome of neonatal apnoea","volume":"9","author":"Baird","year":"2004","journal-title":"Seminars in Neonatology"},{"key":"10.1016\/j.resp.2012.05.013_bib0020","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0034-5687(99)00054-7","article-title":"Dynamic ventilatory responses in rats: normal development and effects of prenatal nicotine exposure","volume":"117","author":"Bamford","year":"1999","journal-title":"Respiration Physiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0025","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.resp.2007.10.013","article-title":"Respiratory plasticity after perinatal hyperoxia is not prevented by antioxidant supplementation","volume":"160","author":"Bavis","year":"2008","journal-title":"Respiratory Physiology and Neurobiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0030","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1203\/PDR.0b013e318186e5f5","article-title":"Prenatal exposure to nicotine affects substance p and preprotachykinin-A mRNA levels in newborn rat","volume":"64","author":"Berner","year":"2008","journal-title":"Pediatric Research"},{"key":"10.1016\/j.resp.2012.05.013_bib0035","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1152\/japplphysiol.00985.2002","article-title":"Adult carotid chemoafferent responses to hypoxia after 1, 2, and 4 wk of postnatal hyperoxia","volume":"95","author":"Bisgard","year":"2003","journal-title":"Journal of Applied Physiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0040","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1136\/adc.2004.070391","article-title":"Sudden infant death syndrome and sleeping position in pre-term and low birth weight infants: an opportunity for targeted intervention","volume":"91","author":"Blair","year":"2006","journal-title":"Archives of Disease in Childhood"},{"key":"10.1016\/j.resp.2012.05.013_bib0045","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1152\/jappl.1981.51.1.40","article-title":"Effect of carotid body denervation on arousal response to hypoxia in sleeping dogs","volume":"51","author":"Bowes","year":"1981","journal-title":"Journal of Applied Physiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0050","first-page":"644","article-title":"Role of the carotid body and of afferent vagal stimuli in the arousal response to airway occlusion in sleeping dogs","volume":"123","author":"Bowes","year":"1981","journal-title":"American Review of Respiratory Disease"},{"key":"10.1016\/j.resp.2012.05.013_bib0055","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1097\/NEN.0b013e31822c09bc","article-title":"Decreased GABAA receptor binding in the medullary serotonergic system in the sudden infant death syndrome","volume":"70","author":"Broadbelt","year":"2011","journal-title":"Journal of Neuropathology and Experimental Neurology"},{"key":"10.1016\/j.resp.2012.05.013_bib0060","doi-asserted-by":"crossref","DOI":"10.1074\/mcp.M111.009530","article-title":"Brainstem deficiency of the 14-3-3 regulator of serotonin synthesis: a proteomics analysis in the sudden infant death syndrome","volume":"11","author":"Broadbelt","year":"2012","journal-title":"Molecular & Cellular Proteomics"},{"key":"10.1016\/j.resp.2012.05.013_bib0065","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0034-5687(85)90043-X","article-title":"The ventilatory response to hypoxia in the newborn lamb after carotid body denervation","volume":"60","author":"Bureau","year":"1985","journal-title":"Respiration Physiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0070","doi-asserted-by":"crossref","first-page":"7137","DOI":"10.1523\/JNEUROSCI.0544-09.2009","article-title":"Chronic nicotine blunts hypoxic sensitivity in perinatal rat adrenal chromaffin cells via upregulation of KATP channels: role of alpha7 nicotinic acetylcholine receptor and hypoxia-inducible factor-2alpha","volume":"29","author":"Buttigieg","year":"2009","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.resp.2012.05.013_bib0075","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1203\/00006450-199406000-00011","article-title":"Absence of ventilatory responses to alternating breaths of mild hypoxia and air in infants who have had bronchopulmonary dysplasia: implications for the risk of sudden infant death","volume":"35","author":"Calder","year":"1994","journal-title":"Pediatric Research"},{"key":"10.1016\/j.resp.2012.05.013_bib0080","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1093\/sleep\/25.4.388","article-title":"Functional role for cannabinoids in respiratory stability during sleep","volume":"25","author":"Carley","year":"2002","journal-title":"Sleep"},{"key":"10.1016\/j.resp.2012.05.013_bib0085","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/978-90-481-2259-2_34","article-title":"Time-dependence of hyperoxia-induced impairment in peripheral chemoreceptor activity and glomus cell calcium response","volume":"648","author":"Carroll","year":"2009","journal-title":"Advances in Experimental Medicine and Biology"},{"key":"10.1016\/j.resp.2012.05.013_bib0090","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1378\/chest.73.5.667","article-title":"Impaired response to hypoxia after bilateral carotid body resection for treatment of bronchial asthma","volume":"73","author":"Chang","year":"1978","journal-title":"Chest"},{"key":"10.1016\/j.resp.2012.05.013_bib0095","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1542\/peds.63.1.13","article-title":"Ultrastructural abnormalities of the carotid body in sudden infant death syndrome","volume":"63","author":"Cole","year":"1979","journal-title":"Pediatrics"},{"key":"10.1016\/j.resp.2012.05.013_bib0100","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1152\/jappl.1996.80.1.323","article-title":"Age-dependent vulnerability to carotid chemodenervation in piglets","volume":"80","author":"C\u00f4t\u00e9","year":"1996","journal-title":"Journal of Applied Physiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0105","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1164\/ajrccm.155.1.9001336","article-title":"Peripheral chemoreceptors in congenital central hypoventilation syndrome","volume":"155","author":"Cutz","year":"1997","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"key":"10.1016\/j.resp.2012.05.013_bib0110","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S0531-5565(97)00097-1","article-title":"Effect of chronic hyperoxia on young and old rat carotid body ultrastructure","volume":"33","author":"Di Giulio","year":"1998","journal-title":"Experimental Gerontology"},{"key":"10.1016\/j.resp.2012.05.013_bib0115","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1111\/j.1365-2559.1977.tb01657.x","article-title":"The carotid body\u2014a quantitative assessment in children","volume":"1","author":"Dinsdale","year":"1977","journal-title":"Histopathology"},{"key":"10.1016\/j.resp.2012.05.013_bib0120","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.resp.2010.11.007","article-title":"Chronic hyperoxia alters the expression of neurotrophic factors in the carotid body of neonatal rats","volume":"175","author":"Dmitrieff","year":"2011","journal-title":"Respiratory Physiology and Neurobiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0125","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1152\/jappl.1990.68.3.1048","article-title":"Prolonged apnea and impaired survival in piglets after sinus and aortic nerve section","volume":"68","author":"Donnelly","year":"1990","journal-title":"Journal of Applied Physiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0130","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1152\/japplphysiol.01009.2004","article-title":"Perinatal hyperoxia for 14 days increases nerve conduction time and the acute unitary response to hypoxia of rat carotid body chemoreceptor","volume":"99","author":"Donnelly","year":"2005","journal-title":"Journal of Applied Physiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0135","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1113\/jphysiol.1987.sp016766","article-title":"Effects of chronic hypoxia from birth on the ventilatory response to acute hypoxia in the newborn rat","volume":"392","author":"Eden","year":"1987","journal-title":"The Journal of Physiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0140","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1111\/j.1469-7793.1998.519bn.x","article-title":"Chemoafferent degeneration and carotid body hypoplasia following chronic hyperoxia in newborn rats","volume":"509","author":"Erickson","year":"1998","journal-title":"The Journal of Physiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0145","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1203\/00006450-198905000-00009","article-title":"Influence of carotid denervation on the arousal and cardiopulmonary response to rapidly developing hypoxemia in lambs","volume":"25","author":"Fewell","year":"1989","journal-title":"Pediatric Research"},{"key":"10.1016\/j.resp.2012.05.013_bib0150","first-page":"193","article-title":"Influence of carotid-denervation on the arousal and cardiopulmonary responses to alveolar hypercapnia in lambs","volume":"12","author":"Fewell","year":"1989","journal-title":"Journal of Developmental Physiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0155","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1203\/00006450-199010000-00014","article-title":"Influence of carotid denervation on the arousal and cardiopulmonary responses to upper airway obstruction in lambs","volume":"28","author":"Fewell","year":"1990","journal-title":"Pediatric Research"},{"key":"10.1016\/j.resp.2012.05.013_bib0160","doi-asserted-by":"crossref","first-page":"2066","DOI":"10.1152\/jappl.1998.85.6.2066","article-title":"Perinatal nicotine exposure impairs ability of newborn rats to autoresuscitate from apnea during hypoxia","volume":"85","author":"Fewell","year":"1998","journal-title":"Journal of Applied Physiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0165","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1159\/000244052","article-title":"A perspective on neuropathologic findings in victims of sudden infant death syndrome: the triple risk model","volume":"65","author":"Filiano","year":"1994","journal-title":"Biology of the Neonate"},{"key":"10.1016\/j.resp.2012.05.013_bib0170","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/j.sleep.2009.12.014","article-title":"Arousal from sleep mechanisms in infants","volume":"11","author":"Franco","year":"2010","journal-title":"Sleep Medicine"},{"key":"10.1016\/j.resp.2012.05.013_bib0175","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.1152\/jappl.2001.91.5.2157","article-title":"Prenatal nicotine affects catecholamine gene expression in newborn rat carotid body and petrosal ganglion","volume":"91","author":"Gauda","year":"2001","journal-title":"Journal of Applied Physiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0180","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.siny.2003.11.002","article-title":"Maturation of peripheral arterial chemoreceptors in relation to neonatal apnoea","volume":"9","author":"Gauda","year":"2004","journal-title":"Seminars in Neonatology"},{"key":"10.1016\/j.resp.2012.05.013_bib0185","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.resp.2007.02.016","article-title":"Peripheral arterial chemoreceptors and sudden infant death syndrome","volume":"157","author":"Gauda","year":"2007","journal-title":"Respiratory Physiology and Neurobiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0190","first-page":"S136","article-title":"Development of the control of breathing: implications for sleep-related breathing disorders in infants","volume":"23","author":"Gaultier","year":"2000","journal-title":"Sleep"},{"key":"10.1016\/j.resp.2012.05.013_bib0195","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1203\/00006450-198608000-00005","article-title":"Effects of carotid body maturation and terbutaline on the laryngeal chemoreflex in newborn lambs","volume":"20","author":"Grogaard","year":"1986","journal-title":"Pediatric Research"},{"key":"10.1016\/j.resp.2012.05.013_bib0200","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1164\/rccm.200204-289OC","article-title":"Prenatal nicotine exposure blunts the cardiorespiratory response to hypoxia in lambs","volume":"166","author":"Hafstrom","year":"2002","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"key":"10.1016\/j.resp.2012.05.013_bib0205","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1542\/peds.2005-0413","article-title":"Achieved versus intended pulse oximeter saturation in infants born less than 28 weeks\u2019 gestation: the AVIOx study","volume":"118","author":"Hagadorn","year":"2006","journal-title":"Pediatrics"},{"key":"10.1016\/j.resp.2012.05.013_bib0210","unstructured":"Hasan, S.U., Yusuf, K. Rat homologues to the human post neonatal period: models for vulnerability to the Sudden infant death syndrome. Pediatric Pulmonology, in press."},{"key":"10.1016\/j.resp.2012.05.013_bib0215","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1111\/j.1365-2559.1990.tb00790.x","article-title":"Histopathology of the carotid bodies in neonates and infants","volume":"17","author":"Heath","year":"1990","journal-title":"Histopathology"},{"key":"10.1016\/j.resp.2012.05.013_bib0220","first-page":"R811","article-title":"Role of carotid sinus and aortic nerves in respiratory control of infant rats","volume":"251","author":"Hofer","year":"1986","journal-title":"American Journal of Physiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0225","doi-asserted-by":"crossref","first-page":"7575","DOI":"10.1073\/pnas.92.16.7575","article-title":"Functional and developmental studies of the peripheral arterial chemoreceptors in rat: effects of nicotine and possible relation to sudden infant death syndrome","volume":"92","author":"Holgert","year":"1995","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.resp.2012.05.013_bib0230","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0306-9877(96)90225-X","article-title":"Carbon monoxide-does fetal exposure cause sudden infant death syndrome?","volume":"46","author":"Hutter","year":"1996","journal-title":"Medical Hypotheses"},{"key":"10.1016\/j.resp.2012.05.013_bib0235","doi-asserted-by":"crossref","first-page":"R1356","DOI":"10.1152\/ajpregu.00884.2007","article-title":"Chronic intermittent hypoxia reduces ventilatory long-term facilitation and enhances apnea frequency in newborn rats","volume":"294","author":"Julien","year":"2008","journal-title":"American Journal of Physiology. Regulatory, Integrative and Comparative Physiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0240","doi-asserted-by":"crossref","first-page":"R192","DOI":"10.1152\/ajpregu.00707.2009","article-title":"Carotid sinus nerve stimulation but not intermittent hypoxia, induces respiratory LTF in adult rats exposed to neonatal intermittent hypoxia","volume":"299","author":"Julien","year":"2010","journal-title":"American Journal of Physiology. Regulatory, Integrative and Comparative Physiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0245","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/S0022-3476(05)81554-9","article-title":"Relationship of maternal substance abuse to subsequent sudden infant death syndrome in offspring","volume":"123","author":"Kandall","year":"1993","journal-title":"Journal of Pediatrics"},{"key":"10.1016\/j.resp.2012.05.013_bib0250","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1093\/sleep\/15.4.287","article-title":"Sleep and cardiorespiratory characteristics of infant victims of sudden death: a prospective case\u2013control study","volume":"15","author":"Kahn","year":"1992","journal-title":"Sleep"},{"issue":"Suppl.","key":"10.1016\/j.resp.2012.05.013_bib0255","doi-asserted-by":"crossref","first-page":"S147","DOI":"10.1016\/j.earlhumdev.2003.08.018","article-title":"Sudden infant deaths: stress, arousal and SIDS","volume":"75","author":"Kahn","year":"2003","journal-title":"Early Human Development"},{"key":"10.1016\/j.resp.2012.05.013_bib0260","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1152\/japplphysiol.00574.2003","article-title":"Measurement of the CO2 apneic threshold in newborn infants: possible relevance for periodic breathing and apnea","volume":"98","author":"Khan","year":"2005","journal-title":"Journal of Applied Physiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0265","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1056\/NEJMra0803836","article-title":"The sudden infant death syndrome","volume":"361","author":"Kinney","year":"2009","journal-title":"New England Journal of Medicine"},{"key":"10.1016\/j.resp.2012.05.013_bib0270","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1542\/peds.114.1.234","article-title":"Sudden infant death syndrome and unclassified sudden infant deaths: a definitional and diagnostic approach","volume":"114","author":"Krous","year":"2004","journal-title":"Pediatrics"},{"key":"10.1016\/j.resp.2012.05.013_bib0275","doi-asserted-by":"crossref","first-page":"335","DOI":"10.3109\/15513818609037724","article-title":"Carotid bodies in sudden infant death syndrome: a combined light microscopic, ultrastructural, and biochemical study","volume":"6","author":"Lack","year":"1986","journal-title":"Pediatric Pathology"},{"key":"10.1016\/j.resp.2012.05.013_bib0280","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/0034-5687(93)90050-K","article-title":"CO reveals dual mechanisms of O2 chemoreception in the cat carotid body","volume":"94","author":"Lahiri","year":"1993","journal-title":"Respiration Physiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0285","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1038\/sj.jp.7211500","article-title":"Pulse oximetry in very low birth weight infants: can oxygen saturation be maintained in the desired range?","volume":"26","author":"Laptook","year":"2006","journal-title":"Journal of Perinatology"},{"key":"10.1016\/j.resp.2012.05.013_bib0290","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/S0022-3476(95)70155-9","article-title":"Deficient hypoxia awakening response in infants of smoking mothers: possible relationship to sudden infant death syndrome","volume":"127","author":"Lewis","year":"1995","journal-title":"Journal of Pediatrics"},{"key":"10.1016\/j.resp.2012.05.013_bib0295","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1113\/jphysiol.1997.sp022058","article-title":"Integrated phrenic responses to carotid afferent stimulation in adult rats following perinatal hyperoxia","volume":"500","author":"Ling","year":"1997","journal-title":"The Journal of Physiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0300","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/S0892-0362(96)90027-6","article-title":"Prenatal cocaine exposure and postnatal hypoxia independently decrease carotid body dopamine in neonatal rats","volume":"18","author":"Lipton","year":"1996","journal-title":"Neurotoxicology and Teratology"},{"key":"10.1016\/j.resp.2012.05.013_bib0305","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0165-3806(99)00127-3","article-title":"Prenatal cocaine exposure reduces glial cell line-derived neurotrophic factor (GDNF) in the striatum and the carotid body of the rat: implications for DA neurodevelopment","volume":"118","author":"Lipton","year":"1999","journal-title":"Brain Research. Developmental Brain Research"},{"key":"10.1016\/j.resp.2012.05.013_bib0310","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.taap.2011.09.023","article-title":"Effects of cigarette smoke exposure on nicotinic acetylcholine receptor subunits \u03b17 and \u03b22 in the sudden infant death syndrome (SIDS) brainstem","volume":"257","author":"Machaalani","year":"2011","journal-title":"Toxicology and Applied Pharmacology"},{"key":"10.1016\/j.resp.2012.05.013_bib0315","first-page":"467","article-title":"Changes in the cardiovascular chemo-baroreceptors as a possible basis for sudden infant death syndrome (SIDS)","volume":"84","author":"Matturri","year":"1992","journal-title":"Pathologica"},{"key":"10.1016\/j.resp.2012.05.013_bib0320","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1203\/00006450-199801000-00019","article-title":"The effect of prenatal exposure to carbon monoxide on breathing and growth of the newborn guinea pig","volume":"43","author":"McGregor","year":"1998","journal-title":"Pediatric Research"},{"key":"10.1016\/j.resp.2012.05.013_bib0325","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.1152\/japplphysiol.00378.2004","article-title":"Cannabinoid receptor expression in peripheral arterial chemoreceptors during postnatal development","volume":"97","author":"McLemore","year":"2004","journal-title":"Journal of Applied Physiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0330","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1111\/j.1476-5381.1980.tb10939.x","article-title":"Inhibitory actions of methionine-enkephalin and morphine on the cat carotid chemoreceptors","volume":"71","author":"McQueen","year":"1980","journal-title":"British Journal of Pharmacology"},{"key":"10.1016\/j.resp.2012.05.013_bib0335","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/0034-5687(75)90069-9","article-title":"Hypoxia-induced tachypnea in carotid-deafferented cats","volume":"23","author":"Miller","year":"1975","journal-title":"Respiration Physiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0340","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1126\/science.1251191","article-title":"Carotid body in the sudden infant death syndrome","volume":"191","author":"Naeye","year":"1976","journal-title":"Science"},{"key":"10.1016\/j.resp.2012.05.013_bib0345","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.jpeds.2003.11.035","article-title":"Relationship of the ventilatory response to hypoxia with neonatal apnea in preterm infants","volume":"144","author":"Nock","year":"2004","journal-title":"Journal of Pediatrics"},{"key":"10.1016\/j.resp.2012.05.013_bib0350","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.resp.2009.05.010","article-title":"Medullary serotonin defects and respiratory dysfunction in sudden infant death syndrome","volume":"168","author":"Paterson","year":"2009","journal-title":"Respiratory Physiology and Neurobiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0355","first-page":"93","article-title":"Morphometric investigation of carotid body in sudden infant death syndrome","volume":"46","author":"Pavai","year":"2005","journal-title":"Romanian Journal of Morphology and Embryology"},{"key":"10.1016\/j.resp.2012.05.013_bib0360","doi-asserted-by":"crossref","first-page":"2020","DOI":"10.1152\/japplphysiol.00876.2003","article-title":"Intermittent hypoxia augments carotid body and ventilatory response to hypoxia in neonatal rat pups","volume":"97","author":"Peng","year":"2004","journal-title":"Journal of Applied Physiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0365","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1542\/peds.73.5.646","article-title":"Ultrastructure of carotid bodies in sudden infant death syndrome","volume":"73","author":"Perrin","year":"1984","journal-title":"Pediatrics"},{"key":"10.1016\/j.resp.2012.05.013_bib0370","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/S0140-6736(84)90763-3","article-title":"Sudden infant death syndrome: increased carotid-body dopamine and noradrenaline content","volume":"2","author":"Perrin","year":"1984","journal-title":"Lancet"},{"key":"10.1016\/j.resp.2012.05.013_bib0375","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1111\/j.1365-2559.2005.02060.x","article-title":"Histopathology of carotid body in heroin addiction. Possible chemosensitive impairment","volume":"46","author":"Porzionato","year":"2005","journal-title":"Histopathology"},{"key":"10.1016\/j.resp.2012.05.013_bib0380","first-page":"351","article-title":"Peripheral chemoreceptors: postnatal development and cytochemical findings in Sudden Infant Death Syndrome","volume":"23","author":"Porzionato","year":"2008","journal-title":"Histology and Histopathology"},{"key":"10.1016\/j.resp.2012.05.013_bib0385","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1937-6448(08)01001-0","article-title":"Trophic factors in the carotid body","volume":"269","author":"Porzionato","year":"2008","journal-title":"International Review of Cell and Molecular Biology"},{"key":"10.1016\/j.resp.2012.05.013_bib0390","doi-asserted-by":"crossref","first-page":"2580","DOI":"10.1056\/NEJMc0909324","article-title":"Sudden infant death syndrome","volume":"361","author":"Porzionato","year":"2009","journal-title":"New England Journal of Medicine"},{"key":"10.1016\/j.resp.2012.05.013_bib0395","doi-asserted-by":"crossref","unstructured":"Porzionato, A., Rucinski, M., Macchi, V., Stecco, C., Sarasin, G., Sfriso, M.M., Di Giulio, C., Malendowicz, L.K., De Caro, R., 2012 Spexin is expressed in the carotid body and is upregulated by postnatal hyperoxia exposure. Advances in Experimental Medicine and Biology, in press.","DOI":"10.1007\/978-94-007-4584-1_29"},{"key":"10.1016\/j.resp.2012.05.013_bib0400","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.resp.2006.12.009","article-title":"Altered carotid body function by intermittent hypoxia in neonates and adults: relevance to recurrent apneas","volume":"157","author":"Prabhakar","year":"2007","journal-title":"Respiratory Physiology and Neurobiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0405","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s00109-012-0876-1","article-title":"Gaseous messengers in oxygen sensing","volume":"90","author":"Prabhakar","year":"2012","journal-title":"Journal of Molecular Medicine"},{"key":"10.1016\/j.resp.2012.05.013_bib0410","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/j.nut.2005.04.002","article-title":"Comparing rat's to human's age: how old is my rat in people years?","volume":"21","author":"Quinn","year":"2005","journal-title":"Nutrition"},{"key":"10.1016\/j.resp.2012.05.013_bib0415","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1161\/hh1701.095632","article-title":"O(2) modulates large-conductance Ca(2+)-dependent K(+) channels of rat chemoreceptor cells by a membrane-restricted and CO-sensitive mechanism","volume":"89","author":"Riesco-Fagundo","year":"2001","journal-title":"Circulation Research"},{"key":"10.1016\/j.resp.2012.05.013_bib0420","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1113\/jphysiol.2001.012705","article-title":"Prenatal nicotine exposure increases apnoea and reduces nicotinic potentiation of hypoglossal inspiratory output in mice","volume":"538","author":"Robinson","year":"2002","journal-title":"The Journal of Physiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0425","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/j.1651-2227.2001.tb00256.x","article-title":"Maternal cannabis use in the sudden death syndrome","volume":"90","author":"Scragg","year":"2001","journal-title":"Acta Paediatrica"},{"key":"10.1016\/j.resp.2012.05.013_bib0430","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/978-1-4615-2572-1_64","article-title":"Postmortem changes in the human carotid body","volume":"360","author":"Seker","year":"1994","journal-title":"Advances in Experimental Medicine and Biology"},{"key":"10.1016\/j.resp.2012.05.013_bib0435","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1203\/00006450-199312000-00025","article-title":"Long-lasting effect of prolonged hypoxemia after birth on the immediate ventilatory response to changes in arterial partial pressure of oxygen in young lambs","volume":"34","author":"Sladek","year":"1993","journal-title":"Pediatric Research"},{"key":"10.1016\/j.resp.2012.05.013_bib0440","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/0361-9230(95)00073-N","article-title":"Loss of neonatal hypoxia tolerance after prenatal nicotine exposure: implications for sudden infant death syndrome","volume":"38","author":"Slotkin","year":"1995","journal-title":"Brain Research Bulletin"},{"key":"10.1016\/j.resp.2012.05.013_bib0445","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.resp.2010.02.015","article-title":"An interdependent model of central\/peripheral chemoreception: evidence and implications for ventilatory control","volume":"173","author":"Smith","year":"2010","journal-title":"Respiratory Physiology and Neurobiology"},{"issue":"Suppl. 1","key":"10.1016\/j.resp.2012.05.013_bib0450","doi-asserted-by":"crossref","first-page":"S28","DOI":"10.1038\/jp.2008.47","article-title":"Clinical practices in neonatal oxygenation: where have we failed? What can we do?","volume":"28","author":"Sola","year":"2008","journal-title":"Journal of Perinatology"},{"key":"10.1016\/j.resp.2012.05.013_bib0455","first-page":"L645","article-title":"Chronic hypoxia abolished the postnatal increase in carotid body type I cell sensitivity to hypoxia","volume":"277","author":"Sterni","year":"1999","journal-title":"American Journal of Physiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0460","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/S0304-3940(99)00364-X","article-title":"Maternal nicotine depresses eupneic ventilation of neonatal rats","volume":"267","author":"St-John","year":"1999","journal-title":"Neuroscience Letters"},{"key":"10.1016\/j.resp.2012.05.013_bib0465","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1378\/chest.78.2.354","article-title":"Bilateral carotid body resection in asthma: vulnerability to hypoxic death in sleep","volume":"78","author":"Sullivan","year":"1980","journal-title":"Chest"},{"key":"10.1016\/j.resp.2012.05.013_bib0470","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.resp.2011.10.004","article-title":"Expression of brain-derived neurotrophic factor and TrkB receptor in the sudden infant death syndrome brainstem","volume":"180","author":"Tang","year":"2012","journal-title":"Respiratory Physiology and Neurobiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0475","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1093\/jnen\/59.3.218","article-title":"Chronic prenatal exposure to carbon monoxide results in a reduction in tyrosine hydroxylase-immunoreactivity and an increase in choline acetyltransferase-immunoreactivity in the fetal medulla: implications for Sudden Infant Death Syndrome","volume":"59","author":"Tolcos","year":"2000","journal-title":"Journal of Neuropathology and Experimental Neurology"},{"key":"10.1016\/j.resp.2012.05.013_bib0480","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1542\/peds.2004-1922","article-title":"Changing conclusions on secondhand smoke in a sudden infant death syndrome review funded by the tobacco industry","volume":"115","author":"Tong","year":"2005","journal-title":"Pediatrics"},{"key":"10.1016\/j.resp.2012.05.013_bib0485","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/S0022-3476(99)70026-0","article-title":"Control of breathing in infants born to smoking mothers","volume":"135","author":"Ueda","year":"1999","journal-title":"Journal of Pediatrics"},{"key":"10.1016\/j.resp.2012.05.013_bib0490","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1542\/peds.66.4.597","article-title":"Sudden infant death syndrome: a review of the medical literature 1974\u20131979","volume":"66","author":"Vald\u00e9s-Dapena","year":"1980","journal-title":"Pediatrics"},{"key":"10.1016\/j.resp.2012.05.013_bib0495","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1016\/S0022-3476(05)80125-8","article-title":"Sudden infant death syndrome in infants of substance-abusing mothers","volume":"117","author":"Ward","year":"1990","journal-title":"Journal of Pediatrics"},{"key":"10.1016\/j.resp.2012.05.013_bib0500","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1152\/jappl.2001.90.3.1065","article-title":"Depression of ventilatory responses after daily, cyclic hypercapnic hypoxia in piglets","volume":"90","author":"Waters","year":"2001","journal-title":"Journal of Applied Physiology"},{"key":"10.1016\/j.resp.2012.05.013_bib0505","doi-asserted-by":"crossref","first-page":"677","DOI":"10.3109\/15513819109065465","article-title":"Defining the Sudden Infant Death Syndrome (SIDS): deliberations of an expert panel convened by the National Institute of Child Health Development","volume":"11","author":"Willinger","year":"1991","journal-title":"Pediatric Pathology"},{"key":"10.1016\/j.resp.2012.05.013_bib0510","doi-asserted-by":"crossref","first-page":"2654","DOI":"10.1016\/j.lfs.2005.10.037","article-title":"Transient carbon monoxide inhibits the ventilatory responses to hypoxia through peripheral mechanisms in the rat","volume":"78","author":"Zhuang","year":"2006","journal-title":"Life Sciences"}],"container-title":["Respiratory Physiology &amp; Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569904812001097?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569904812001097?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T22:29:29Z","timestamp":1761604169000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1569904812001097"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":102,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["S1569904812001097"],"URL":"https:\/\/doi.org\/10.1016\/j.resp.2012.05.013","relation":{},"ISSN":["1569-9048"],"issn-type":[{"value":"1569-9048","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The carotid body in Sudden Infant Death Syndrome","name":"articletitle","label":"Article Title"},{"value":"Respiratory Physiology & Neurobiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.resp.2012.05.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}