{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T02:50:04Z","timestamp":1791255004448,"version":"4.1.0"},"reference-count":73,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Physiology &amp; Neurobiology"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1016\/j.resp.2012.08.009","type":"journal-article","created":{"date-parts":[[2012,8,18]],"date-time":"2012-08-18T00:06:24Z","timestamp":1345248384000},"page":"67-74","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Voltage-gated Na+ channels in chemoreceptor afferent neurons\u2014Potential roles and changes with development"],"prefix":"10.1016","volume":"185","author":[{"given":"David F.","family":"Donnelly","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.resp.2012.08.009_bib0005","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0306-4522(00)00455-3","article-title":"Persistent sodium channel activity mediates subthreshold membrane potential oscillations and low-threshold spikes in rat entorhinal cortex layer V neurons","volume":"102","author":"Agrawal","year":"2001","journal-title":"Neuroscience"},{"key":"10.1016\/j.resp.2012.08.009_bib0010","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1038\/9195","article-title":"The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways","volume":"2","author":"Akopian","year":"1999","journal-title":"Nature Neuroscience"},{"key":"10.1016\/j.resp.2012.08.009_bib0015","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1152\/jn.1993.69.1.290","article-title":"Postnatal development of a persistent Na+ current in pyramidal neurons from rat sensorimotor cortex","volume":"69","author":"Alzheimer","year":"1993","journal-title":"Journal of Neurophysiology"},{"key":"10.1016\/j.resp.2012.08.009_bib0020","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1113\/jphysiol.1983.sp014871","article-title":"Membrane properties of cat sensory neurones with chemoreceptor and baroreceptor endings","volume":"342","author":"Belmonte","year":"1983","journal-title":"Journal of Physiology (London)"},{"key":"10.1016\/j.resp.2012.08.009_bib0025","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1113\/jphysiol.1988.sp017330","article-title":"Membrane properties of primary sensory neurones of the cat after peripheral reinnervation","volume":"405","author":"Belmonte","year":"1988","journal-title":"Journal of Physiology (London)"},{"key":"10.1016\/j.resp.2012.08.009_bib0030","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1113\/jphysiol.1963.sp007195","article-title":"The discharge pattern recorded in chemoreceptor afferent fibres from the cat carotid body with normal circulation and during perfusion","volume":"168","author":"Biscoe","year":"1963","journal-title":"Journal of Physiology (London)"},{"key":"10.1016\/j.resp.2012.08.009_bib0035","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0896-6273(01)00265-3","article-title":"Compact myelin dictates the differential targeting of two sodium channel isoforms in the same axon","volume":"30","author":"Boiko","year":"2001","journal-title":"Neuron"},{"key":"10.1016\/j.resp.2012.08.009_bib0040","doi-asserted-by":"crossref","first-page":"2306","DOI":"10.1523\/JNEUROSCI.23-06-02306.2003","article-title":"Functional specialization of the axon initial segment by isoform-specific sodium channel targeting","volume":"23","author":"Boiko","year":"2003","journal-title":"Journal of Neuroscience"},{"issue":"Pt 1","key":"10.1016\/j.resp.2012.08.009_bib0045","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1111\/j.1469-7793.1998.211bf.x","article-title":"Tetrodotoxin-resistant impulses in single nociceptor nerve terminals in guinea-pig cornea","volume":"512","author":"Brock","year":"1998","journal-title":"Journal of Physiology"},{"key":"10.1016\/j.resp.2012.08.009_bib0050","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1113\/jphysiol.1994.sp020143","article-title":"Effects of hypoxia on membrane potential and intracellular calcium in rat neonatal carotid body type I cells","volume":"476","author":"Buckler","year":"1994","journal-title":"Journal of Physiology (London)"},{"key":"10.1016\/j.resp.2012.08.009_bib0055","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/S0165-1838(97)00098-2","article-title":"Dopamine increases in cat carotid body during excitation by carbon monoxide: implications for a chromophore theory of chemoreception","volume":"67","author":"Buerk","year":"1997","journal-title":"Journal of the Autonomic Nervous System"},{"key":"10.1016\/j.resp.2012.08.009_bib0060","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.bbrc.2004.07.081","article-title":"Detection of hypoxia-evoked ATP release from chemoreceptor cells of the rat carotid body","volume":"322","author":"Buttigieg","year":"2004","journal-title":"Biochemical and Biophysical Research Communications"},{"key":"10.1016\/j.resp.2012.08.009_bib0065","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/j.tips.2005.08.002","article-title":"Regulation of Na v channels in sensory neurons","volume":"26","author":"Chahine","year":"2005","journal-title":"Trends in Pharmacological Sciences"},{"key":"10.1016\/j.resp.2012.08.009_bib0070","doi-asserted-by":"crossref","first-page":"3013","DOI":"10.1016\/S0006-3495(96)79494-8","article-title":"Spontaneous action potentials due to channel fluctuations","volume":"71","author":"Chow","year":"1996","journal-title":"Biophysical Journal"},{"key":"10.1016\/j.resp.2012.08.009_bib0075","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1146\/annurev.ph.58.030196.002025","article-title":"Persistent sodium current in mammalian central neurons","volume":"58","author":"Crill","year":"1996","journal-title":"Annual Review of Physiology"},{"key":"10.1016\/j.resp.2012.08.009_bib0080","doi-asserted-by":"crossref","first-page":"2993","DOI":"10.1152\/jn.00350.2002","article-title":"Characterization and developmental changes of Na+ currents of petrosal neurons with projections to the carotid body","volume":"88","author":"Cummins","year":"2002","journal-title":"Journal of Neurophysiology"},{"key":"10.1016\/j.resp.2012.08.009_bib0085","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1038\/32176","article-title":"Synapse-specific control of synaptic efficacy at the terminals of a single neuron","volume":"392","author":"Davis","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.resp.2012.08.009_bib0090","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1113\/jphysiol.2003.042127","article-title":"The TTX-resistant sodium channel Nav1.8 (SNS\/PN3): expression and correlation with membrane properties in rat nociceptive primary afferent neurons","volume":"550","author":"Djouhri","year":"2003","journal-title":"Journal of Physiology"},{"key":"10.1016\/j.resp.2012.08.009_bib0095","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1152\/jappl.1996.81.2.657","article-title":"Chemoreceptor nerve excitation may not be proportional to catecholamine secretion","volume":"81","author":"Donnelly","year":"1996","journal-title":"Journal of Applied Physiology"},{"key":"10.1016\/j.resp.2012.08.009_bib0100","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1152\/jn.1999.82.1.209","article-title":"Developmental changes in membrane properties of chemoreceptor afferent neurons of the rat petrosal ganglia","volume":"82","author":"Donnelly","year":"1999","journal-title":"Journal of Neurophysiology"},{"key":"10.1016\/j.resp.2012.08.009_bib0105","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.resp.2011.05.002","article-title":"Developmental changes in the magnitude and activation characteristics of Na(+) currents of petrosal neurons projecting to the carotid body","volume":"177","author":"Donnelly","year":"2011","journal-title":"Respiratory Physiology and Neurobiology"},{"key":"10.1016\/j.resp.2012.08.009_bib0110","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1111\/j.1469-7793.1998.301bi.x","article-title":"Effect of sodium perturbations on rat chemoreceptor spike generation: implications for a Poisson model","volume":"511","author":"Donnelly","year":"1998","journal-title":"Journal of Physiology (London)"},{"key":"10.1016\/j.resp.2012.08.009_bib0115","first-page":"24P","article-title":"Effect of hyperoxia from birth on the carotid chemoreceptor and ventilatory responses of rats to acute hypoxia","volume":"374","author":"Eden","year":"1986","journal-title":"Journal of Physiology (London)"},{"key":"10.1016\/j.resp.2012.08.009_bib0120","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1113\/jphysiol.1987.sp016766","article-title":"Effects of chronic hypoxia from birth on the ventilatory response to acute hypoxia in the newborn rat","volume":"392","author":"Eden","year":"1987","journal-title":"Journal of Physiology (London)"},{"key":"10.1016\/j.resp.2012.08.009_bib0125","doi-asserted-by":"crossref","first-page":"341","DOI":"10.4067\/S0716-97602005000400005","article-title":"Chemical and electric transmission in the carotid body chemoreceptor complex","volume":"38","author":"Eyzaguirre","year":"2005","journal-title":"Biological Research"},{"key":"10.1016\/j.resp.2012.08.009_bib0130","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1113\/jphysiol.1965.sp007634","article-title":"Effects of hypoxia, hypercapnia and pH on the chemoreceptor activity of the carotid body in vitro","volume":"178","author":"Eyzaguirre","year":"1965","journal-title":"Journal of Physiology (London)"},{"key":"10.1016\/j.resp.2012.08.009_bib0135","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1152\/japplphysiol.00090.2006","article-title":"An important functional role of persistent Na+ current in carotid body hypoxia transduction","volume":"101","author":"Faustino","year":"2006","journal-title":"Journal of Applied Physiology"},{"key":"10.1016\/j.resp.2012.08.009_bib0140","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1152\/japplphysiol.00633.2006","article-title":"Lamotrigine and phenytoin, but not amiodarone, impair peripheral chemoreceptor responses to hypoxia","volume":"101","author":"Faustino","year":"2006","journal-title":"Journal of Applied Physiology"},{"key":"10.1016\/j.resp.2012.08.009_bib0145","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1016\/j.bbrc.2004.09.188","article-title":"Acute and chronic hypoxic regulation of recombinant hNa(v)1.5 alpha subunits","volume":"324","author":"Fearon","year":"2004","journal-title":"Biochemical and Biophysical Research Communications"},{"key":"10.1016\/j.resp.2012.08.009_bib0150","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.brainres.2009.02.078","article-title":"The impact of hypoxia and low glucose on the release of acetylcholine and ATP from the incubated cat carotid body","volume":"1270","author":"Fitzgerald","year":"2009","journal-title":"Brain Research"},{"key":"10.1016\/j.resp.2012.08.009_bib0155","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1113\/jphysiol.1983.sp014870","article-title":"The ionic basis of action potentials in petrosal ganglion cells of the cat","volume":"342","author":"Gallego","year":"1983","journal-title":"Journal of Physiology (London)"},{"key":"10.1016\/j.resp.2012.08.009_bib0160","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1002\/(SICI)1096-9861(19990920)412:2<342::AID-CNE11>3.0.CO;2-2","article-title":"Type I and type II Na(+) channel alpha-subunit polypeptides exhibit distinct spatial and temporal patterning, and association with auxiliary subunits in rat brain","volume":"412","author":"Gong","year":"1999","journal-title":"Journal of Comparative Neurology"},{"key":"10.1016\/j.resp.2012.08.009_bib0165","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1007\/BF00207702","article-title":"Improved demonstration of exocytotic profiles in glomus cells of rat carotid body after perfusion with glutaraldehyde fixative containing a high concentration of potassium","volume":"229","author":"Gronblad","year":"1983","journal-title":"Cell and Tissue Research"},{"key":"10.1016\/j.resp.2012.08.009_bib0170","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1111\/j.1469-7793.1998.735bj.x","article-title":"Inhibition of oxidative metabolism increases persistent sodium current in rat CA1 hippocampal neurons","volume":"510","author":"Hammarstrom","year":"1998","journal-title":"Journal of Physiology (London)"},{"key":"10.1016\/j.resp.2012.08.009_bib0175","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1111\/j.1469-7793.2000.00107.x","article-title":"Oxygen-sensing persistent sodium channels in rat hippocampus","volume":"529","author":"Hammarstrom","year":"2000","journal-title":"Journal of Physiology (London)"},{"key":"10.1016\/j.resp.2012.08.009_bib0180","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1113\/jphysiol.1989.sp017590","article-title":"The effect of chronic hypoxia upon the development of respiratory chemoreflexes in the newborn kitten","volume":"411","author":"Hanson","year":"1989","journal-title":"Journal of Physiology (London)"},{"key":"10.1016\/j.resp.2012.08.009_bib0185","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1113\/jphysiol.1952.sp004764","article-title":"A quantitative description of membrane current and its application to conduction and excitation in nerve","volume":"10","author":"Hodgkin","year":"1952","journal-title":"Journal of Physiology (London)"},{"key":"10.1016\/j.resp.2012.08.009_bib0190","doi-asserted-by":"crossref","first-page":"2572","DOI":"10.1152\/jn.2000.84.5.2572","article-title":"Hypoxic augmentation of fast-inactivating and persistent sodium currents in rat caudal hypothalamic neurons","volume":"84","author":"Horn","year":"2000","journal-title":"Journal of Neurophysiology"},{"key":"10.1016\/j.resp.2012.08.009_bib0195","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1113\/jphysiol.1996.sp021788","article-title":"Dissociation of hypoxia-induced chemosensory responses and catecholamine efflux in cat carotid body superfused in vitro","volume":"497","author":"Iturriaga","year":"1996","journal-title":"Journal of Physiology (London)"},{"key":"10.1016\/j.resp.2012.08.009_bib0200","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.resp.2006.12.006","article-title":"Electrical and pharmacological properties of petrosal ganglion neurons that innervate the carotid body","volume":"157","author":"Iturriaga","year":"2007","journal-title":"Respiratory Physiology and Neurobiology"},{"key":"10.1016\/j.resp.2012.08.009_bib0205","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.brainres.2005.08.059","article-title":"Effects of prolonged hypobaric hypoxia on carotid nerve endings and glomus cells. Changes in intercellular coupling","volume":"1076","author":"Jiang","year":"2006","journal-title":"Brain Research"},{"key":"10.1016\/j.resp.2012.08.009_bib0210","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1113\/jphysiol.1996.sp021772","article-title":"Hypoxia increases persistent sodium current in rat ventricular myocytes","volume":"497","author":"Ju","year":"1996","journal-title":"Journal of Physiology (London)"},{"key":"10.1016\/j.resp.2012.08.009_bib0215","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1113\/jphysiol.1992.sp019239","article-title":"Maturation of carotid chemoreceptor sensitivity to hypoxia: in vitro studies in the newborn rat","volume":"453","author":"Kholwadwala","year":"1992","journal-title":"Journal of Physiology (London)"},{"key":"10.1016\/j.resp.2012.08.009_bib0220","series-title":"Regeneration of Nerves and Nerve Terminals in Rabbit Carotid Body Following Carotid Nerve Sectioning and Suturing","author":"Kienecker","year":"1977"},{"key":"10.1016\/j.resp.2012.08.009_bib0225","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1016\/0306-4522(78)90118-5","article-title":"Functional properties of regenerating sinus nerve fibres in the rabbit","volume":"3","author":"Kienecker","year":"1978","journal-title":"Neuroscience"},{"key":"10.1016\/j.resp.2012.08.009_bib0230","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0034-5687(92)90058-5","article-title":"Carotid chemoreceptor response to natural stimuli in the newborn kitten","volume":"87","author":"Marchal","year":"1992","journal-title":"Respiration Physiology"},{"key":"10.1016\/j.resp.2012.08.009_bib0235","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/BF01098781","article-title":"The innervation of glomus cells, ganglion cells and blood vessels in the rat carotid body: a quantitative ultrastructural analysis","volume":"4","author":"McDonald","year":"1975","journal-title":"Journal of Neurocytology"},{"key":"10.1016\/j.resp.2012.08.009_bib0240","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/0006-8993(72)90430-1","article-title":"Chemoreceptive properties of regenerated endings of the carotid sinus nerve","volume":"43","author":"Mitchell","year":"1972","journal-title":"Brain Research"},{"key":"10.1016\/j.resp.2012.08.009_bib0245","series-title":"Developmental Neurobiology of Breathing","first-page":"321","article-title":"Discharge properties of carotid bodies: developmental aspects","author":"Mulligan","year":"1991"},{"key":"10.1016\/j.resp.2012.08.009_bib0250","doi-asserted-by":"crossref","first-page":"12706","DOI":"10.1073\/pnas.0404915101","article-title":"Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain","volume":"101","author":"Nassar","year":"2004","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.resp.2012.08.009_bib0255","doi-asserted-by":"crossref","first-page":"2174","DOI":"10.1523\/JNEUROSCI.18-06-02174.1998","article-title":"Distribution of the tetrodotoxin-resistant sodium channel PN3 in rat sensory neurons in normal and neuropathic conditions","volume":"18","author":"Novakovic","year":"1998","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.resp.2012.08.009_bib0260","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1113\/jphysiol.1995.sp020749","article-title":"Postnatal development of CO2\u2013O2 interaction in the rat carotid body in vitro","volume":"485","author":"Pepper","year":"1995","journal-title":"Journal of Physiology (London)"},{"key":"10.1016\/j.resp.2012.08.009_bib0265","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.resp.2006.07.006","article-title":"Carotid body chemosensory activity and ventilatory chemoreflexes in cats persist after combined cholinergic\u2013purinergic block","volume":"156","author":"Reyes","year":"2007","journal-title":"Respiratory Physiology and Neurobiology"},{"key":"10.1016\/j.resp.2012.08.009_bib0270","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.resp.2006.07.007","article-title":"Effects of combined cholinergic\u2013purinergic block upon cat carotid body chemoreceptors in vitro","volume":"156","author":"Reyes","year":"2007","journal-title":"Respiratory Physiology and Neurobiology"},{"key":"10.1016\/j.resp.2012.08.009_bib0275","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1113\/jphysiol.2005.083089","article-title":"Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones","volume":"564","author":"Rush","year":"2005","journal-title":"Journal of Physiology"},{"key":"10.1016\/j.resp.2012.08.009_bib0280","doi-asserted-by":"crossref","first-page":"2220","DOI":"10.1152\/jn.1995.74.5.2220","article-title":"Amplification of synaptic current by persistent sodium conductance in apical dendrite of neocortical neurons","volume":"74","author":"Schwindt","year":"1995","journal-title":"Journal of Neurophysiology"},{"key":"10.1016\/j.resp.2012.08.009_bib0285","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1097\/00001756-200207020-00019","article-title":"Lamotrigine derivatives and riluzole inhibit INa,P in cortical neurons","volume":"13","author":"Spadoni","year":"2002","journal-title":"Neuroreport"},{"key":"10.1016\/j.resp.2012.08.009_bib0290","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/0306-4522(92)90180-A","article-title":"Whole-cell currents in two subpopulations of cultured rat petrosal neurons with different tetrodotoxin sensitivities","volume":"47","author":"Stea","year":"1992","journal-title":"Neuroscience"},{"key":"10.1016\/j.resp.2012.08.009_bib0295","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1016\/0896-6273(95)90095-0","article-title":"Amplification of EPSPs by axosomatic sodium channels in neocortical pyramidal neurons","volume":"15","author":"Stuart","year":"1995","journal-title":"Neuron"},{"key":"10.1016\/j.resp.2012.08.009_bib0300","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/S0896-6273(02)00574-3","article-title":"Subthreshold sodium current from rapidly inactivating sodium channels drives spontaneous firing of tuberomammillary neurons","volume":"33","author":"Taddese","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.resp.2012.08.009_bib0305","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1152\/jn.00573.2002","article-title":"Fast rhythmic bursting can be induced in layer 2\/3 cortical neurons by enhancing persistent Na+ conductance or by blocking BK channels","volume":"89","author":"Traub","year":"2003","journal-title":"Journal of Neurophysiology"},{"key":"10.1016\/j.resp.2012.08.009_bib0310","doi-asserted-by":"crossref","first-page":"3567","DOI":"10.1046\/j.1460-9568.2000.00242.x","article-title":"Riluzole inhibits the persistent sodium current in mammalian CNS neurons","volume":"12","author":"Urbani","year":"2000","journal-title":"European Journal of Neuroscience"},{"key":"10.1016\/j.resp.2012.08.009_bib0315","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1002\/cne.21173","article-title":"Polarized distribution of ion channels within microdomains of the axon initial segment","volume":"500","author":"Van Wart","year":"2007","journal-title":"Journal of Comparative Neurology"},{"key":"10.1016\/j.resp.2012.08.009_bib0320","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/S0006-8993(03)03366-3","article-title":"ACh and ATP mediate excitatory transmission in cat carotid identified chemoreceptor units in vitro","volume":"988","author":"Varas","year":"2003","journal-title":"Brain Research"},{"key":"10.1016\/j.resp.2012.08.009_bib0325","series-title":"The Carotid Body Chemoreceptors","first-page":"1","article-title":"The mammalian carotid body: morphological data","author":"Verna","year":"1997"},{"key":"10.1016\/j.resp.2012.08.009_bib0330","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.resp.2006.01.003","article-title":"Postnatal development of carotid body glomus cell response to hypoxia","volume":"154","author":"Wasicko","year":"2006","journal-title":"Respiratory Physiology and Neurobiology"},{"key":"10.1016\/j.resp.2012.08.009_bib0335","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1111\/j.1469-7793.1999.493ae.x","article-title":"Resetting and postnatal maturation of oxygen chemosensitivity in rat carotid chemoreceptor cells","volume":"514","author":"Wasicko","year":"1999","journal-title":"Journal of Physiology (London)"},{"key":"10.1016\/j.resp.2012.08.009_bib0340","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/0896-6273(89)90238-9","article-title":"Differential subcellular localization of the RI and RII Na+ channel subtypes in central neurons","volume":"3","author":"Westenbroek","year":"1989","journal-title":"Neuron"},{"key":"10.1016\/j.resp.2012.08.009_bib0345","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/S0301-0082(00)00055-1","article-title":"Safety factor at the neuromuscular junction","volume":"64","author":"Wood","year":"2001","journal-title":"Progress in Neurobiology"},{"key":"10.1016\/j.resp.2012.08.009_bib0350","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1080\/10298420290007646","article-title":"Differential pattern of expression of voltage-gated sodium channel genes following ischemic brain injury in rats","volume":"4","author":"Yao","year":"2002","journal-title":"Neurotoxicity Research"},{"key":"10.1016\/j.resp.2012.08.009_bib0355","doi-asserted-by":"crossref","first-page":"2790","DOI":"10.1152\/jn.1997.78.5.2790","article-title":"Axotomy increases the excitability of doral root ganglion cells with unmyelinated axons","volume":"78","author":"Zhang","year":"1997","journal-title":"Journal of Neurophysiology"},{"key":"10.1016\/j.resp.2012.08.009_bib0360","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1111\/j.1469-7793.1997.599bg.x","article-title":"Synapse formation and hypoxic signalling in co-cultures of rat petrosal neurones and carotid body type 1 cells","volume":"503","author":"Zhong","year":"1997","journal-title":"Journal of Physiology (London)"},{"key":"10.1016\/j.resp.2012.08.009_bib0365","doi-asserted-by":"crossref","first-page":"2254","DOI":"10.1152\/jn.90437.2008","article-title":"Persistent sodium current contributes to induced voltage oscillations in locomotor-related hb9 interneurons in the mouse spinal cord","volume":"100","author":"Ziskind-Conhaim","year":"2008","journal-title":"Journal of Neurophysiology"}],"container-title":["Respiratory Physiology &amp; Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569904812002303?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569904812002303?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T22:28:10Z","timestamp":1761604090000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1569904812002303"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":73,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["S1569904812002303"],"URL":"https:\/\/doi.org\/10.1016\/j.resp.2012.08.009","relation":{},"ISSN":["1569-9048"],"issn-type":[{"value":"1569-9048","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Voltage-gated Na+ channels in chemoreceptor afferent neurons\u2014Potential roles and changes with development","name":"articletitle","label":"Article Title"},{"value":"Respiratory Physiology & Neurobiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.resp.2012.08.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}