{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T16:29:11Z","timestamp":1781886551000,"version":"3.54.5"},"reference-count":140,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T00:00:00Z","timestamp":1383264000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T00:00:00Z","timestamp":1383264000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"NHLBI Training","award":["HL007654"],"award-info":[{"award-number":["HL007654"]}]},{"DOI":"10.13039\/100005834","name":"Francis Families Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100005834","id-type":"DOI","asserted-by":"crossref"}]},{"name":"NHLBI Training","award":["HL007654"],"award-info":[{"award-number":["HL007654"]}]},{"name":"NIH Training","award":["RR023916"],"award-info":[{"award-number":["RR023916"]}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Physiology &amp; Neurobiology"],"published-print":{"date-parts":[[2013,11]]},"DOI":"10.1016\/j.resp.2013.05.016","type":"journal-article","created":{"date-parts":[[2013,5,18]],"date-time":"2013-05-18T19:00:51Z","timestamp":1368903651000},"page":"429-437","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":54,"title":["Ventilatory control in ALS"],"prefix":"10.1016","volume":"189","author":[{"given":"Nicole L.","family":"Nichols","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Van Dyke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Nashold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Satriotomo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.S.","family":"Mitchell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.resp.2013.05.016_bib0005","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1177\/1479972309345927","article-title":"Mechanisms of exercise limitation and pulmonary rehabilitation for patients with neuromuscular disease","volume":"6","author":"Aboussouan","year":"2009","journal-title":"Chronic Respiratory Disease"},{"key":"10.1016\/j.resp.2013.05.016_bib0010","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1002\/ana.410360608","article-title":"The role of calcium-binding proteins in selective motoneuron vulnerability in amyotrophic lateral sclerosis","volume":"36","author":"Alexianu","year":"1994","journal-title":"Annals of Neurology"},{"key":"10.1016\/j.resp.2013.05.016_bib0015","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/0304-3940(91)90418-S","article-title":"Production of nerve growth factor in rat skeletal muscle","volume":"132","author":"Amano","year":"1991","journal-title":"Neuroscience Letters"},{"key":"10.1016\/j.resp.2013.05.016_bib0020","first-page":"62","volume":"4","author":"Andersen","year":"2003","journal-title":"Research Group on Motor Neuron Diseases"},{"key":"10.1016\/j.resp.2013.05.016_bib0025","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1164\/ajrccm.161.3.9805008","article-title":"Sleep disorders and diaphragmatic function in patients with amyotrophic lateral sclerosis","volume":"161","author":"Arnulf","year":"2000","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"key":"10.1016\/j.resp.2013.05.016_bib0030","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1080\/17482960601029883","article-title":"Sleep characteristics of amyotrophic lateral sclerosis in patients with preserved diaphragmatic function","volume":"8","author":"Atalaia","year":"2007","journal-title":"Amyotrophic Lateral Sclerosis"},{"key":"10.1016\/j.resp.2013.05.016_bib0035","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1038\/nn1166","article-title":"BDNF is necessary and sufficient for spinal respiratory plasticity following intermittent hypoxia","volume":"7","author":"Baker-Herman","year":"2004","journal-title":"Nature Neuroscience"},{"key":"10.1016\/j.resp.2013.05.016_bib0040","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1152\/jappl.1981.51.3.660","article-title":"Effect of transrespiratory pressure on PETCO2\u2013PaCO2 and ventilatory reflexes in humans","volume":"51","author":"Banzett","year":"1981","journal-title":"Journal of Applied Physiology"},{"key":"10.1016\/j.resp.2013.05.016_bib0045","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.1097\/00001756-200007140-00012","article-title":"Breathlessness in humans activates insular cortex","volume":"11","author":"Banzett","year":"2000","journal-title":"Neuroreport"},{"key":"10.1016\/j.resp.2013.05.016_bib0050","first-page":"829","article-title":"The neuromuscular respiratory system: physiology, pathophysiology, and a respiratory care approach to patients","volume":"51","author":"Benditt","year":"2006","journal-title":"Respiratory Care"},{"key":"10.1016\/j.resp.2013.05.016_bib0055","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.clineuro.2012.02.049","article-title":"Inspiratory- and finger-flexion-related cortical potentials in patients with amyotrophic lateral sclerosis\u2014an exploratory study","volume":"114","author":"Bizovicar","year":"2012","journal-title":"Clinical Neurology and Neurosurgery"},{"issue":"6","key":"10.1016\/j.resp.2013.05.016_bib0060","doi-asserted-by":"crossref","first-page":"2964","DOI":"10.1152\/jn.2002.87.6.2964","article-title":"Long-term modulation of respiratory network activity following anoxia in vitro","volume":"87","author":"Blitz","year":"2002","journal-title":"Journal of Neurophysiology"},{"key":"10.1016\/j.resp.2013.05.016_bib0065","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.neuron.2006.09.018","article-title":"ALS: a disease of motor neurons and their nonneuronal neighbors","volume":"52","author":"Boillee","year":"2006","journal-title":"Neuron"},{"key":"10.1016\/j.resp.2013.05.016_bib0070","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.resp.2009.07.018","article-title":"Recovery of airway protective behaviors after spinal cord injury","volume":"169","author":"Bolser","year":"2009","journal-title":"Respiratory Physiology & Neurobiology"},{"issue":"Suppl.","key":"10.1016\/j.resp.2013.05.016_bib0075","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1038\/nm1067","article-title":"Molecular pathways to neurodegeneration","volume":"10","author":"Bossy-Wetzel","year":"2004","journal-title":"Nature Medicine"},{"key":"10.1016\/j.resp.2013.05.016_bib0080","doi-asserted-by":"crossref","first-page":"2040","DOI":"10.1212\/WNL.57.11.2040","article-title":"Respiratory function vs sleep-disordered breathing as predictors of QOL in ALS","volume":"57","author":"Bourke","year":"2001","journal-title":"Neurology"},{"key":"10.1016\/j.resp.2013.05.016_bib0085","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1146\/annurev.neuro.27.070203.144244","article-title":"Unraveling the mechanisms involved in motor neuron degeneration in ALS","volume":"27","author":"Bruijn","year":"2004","journal-title":"Annual Review of Neuroscience"},{"key":"10.1016\/j.resp.2013.05.016_bib0090","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1023\/A:1018687923929","article-title":"Paralysis of rat skeletal muscle equally affects contractile properties as does permanent denervation","volume":"18","author":"Buffelli","year":"1997","journal-title":"Journal of Muscle Research and Cell Motility"},{"key":"10.1016\/j.resp.2013.05.016_bib0095","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.brainres.2009.11.051","article-title":"Moderate exercise delays the motor performance decline in a transgenic model of ALS","volume":"1313","author":"Carreras","year":"2010","journal-title":"Brain Research"},{"issue":"1","key":"10.1016\/j.resp.2013.05.016_bib0100","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1080\/146608201300079373","article-title":"Disease status and use of ventilatory support by ALS patients. BDNF Study Group","volume":"2","author":"Cedarbaum","year":"2001","journal-title":"Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders"},{"key":"10.1016\/j.resp.2013.05.016_bib0105","first-page":"745","article-title":"Deux cas d\u2019atrophie musculaire progressive avec lesion de la substance grise et des faisceaux antero-lateraux de la moelle epiniere","author":"Charcot","year":"1869","journal-title":"Archiv fur Psychologie Normale et Pathologique"},{"key":"10.1016\/j.resp.2013.05.016_bib0110","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.resp.2011.03.017","article-title":"Respiratory motoneurons and pathological conditions: lessons from hypoglossal motoneurons challenged by excitotoxic or oxidative stress","volume":"179","author":"Cifra","year":"2011","journal-title":"Respiratory Physiology & Neurobiology"},{"key":"10.1016\/j.resp.2013.05.016_bib0115","first-page":"806","article-title":"From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS. Nature reviews","volume":"2","author":"Cleveland","year":"2001","journal-title":"Neuroscience"},{"key":"10.1016\/j.resp.2013.05.016_bib0120","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1136\/mp.54.6.386","article-title":"Mechanisms of neurodegeneration in amyotrophic lateral sclerosis","volume":"MP 54","author":"Cluskey","year":"2001","journal-title":"Molecular Pathology"},{"key":"10.1016\/j.resp.2013.05.016_bib0125","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1080\/17482960701656940","article-title":"Causes of death in a post-mortem series of ALS patients","volume":"9","author":"Corcia","year":"2008","journal-title":"Amyotrophic Lateral Sclerosis"},{"key":"10.1016\/j.resp.2013.05.016_bib0130","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1136\/jnnp.2005.072660","article-title":"Forced vital capacity (FVC) as an indicator of survival and disease progression in an ALS clinic population","volume":"77","author":"Czaplinski","year":"2006","journal-title":"Journal of Neurology, Neurosurgery, and Psychiatry"},{"key":"10.1016\/j.resp.2013.05.016_bib0135","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1249\/00005768-199309000-00006","article-title":"Modulation of IGF mRNA abundance during muscle denervation atrophy","volume":"25","author":"Czerwinski","year":"1993","journal-title":"Medicine and Science in Sports and Exercise"},{"key":"10.1016\/j.resp.2013.05.016_bib0140","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1007\/s12031-010-9467-1","article-title":"The dying-back phenomenon of motor neurons in ALS","volume":"43","author":"Dadon-Nachum","year":"2011","journal-title":"Journal of Molecular Neuroscience"},{"issue":"1","key":"10.1016\/j.resp.2013.05.016_bib0145","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s10072-011-0921-9","article-title":"Exercise and amyotrophic lateral sclerosis","volume":"33","author":"de Almeida","year":"2012","journal-title":"Neurological Sciences"},{"issue":"Suppl.","key":"10.1016\/j.resp.2013.05.016_bib0150","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0022-510X(96)00089-5","article-title":"Motor neuron disease presenting with respiratory failure","volume":"139","author":"de Carvalho","year":"1996","journal-title":"Journal of the Neurological Sciences"},{"key":"10.1016\/j.resp.2013.05.016_bib0155","doi-asserted-by":"crossref","first-page":"63","DOI":"10.3109\/17482960902730080","article-title":"Association of paraspinal and diaphragm denervation in ALS","volume":"11","author":"de Carvalho","year":"2010","journal-title":"Amyotrophic Lateral Sclerosis"},{"key":"10.1016\/j.resp.2013.05.016_bib0160","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1152\/jn.1987.57.1.245","article-title":"Correlation of recruitment order with axonal conduction velocity for supraspinally driven diaphragmatic motor units","volume":"57","author":"Dick","year":"1987","journal-title":"Journal of Neurophysiology"},{"key":"10.1016\/j.resp.2013.05.016_bib0165","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1006\/nbdi.2002.0522","article-title":"Nogo provides a molecular marker for diagnosis of amyotrophic lateral sclerosis","volume":"10","author":"Dupuis","year":"2002","journal-title":"Neurobiology of Disease"},{"key":"10.1016\/j.resp.2013.05.016_bib0170","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.coph.2009.03.007","article-title":"Neuromuscular junction destruction during amyotrophic lateral sclerosis: insights from transgenic models","volume":"9","author":"Dupuis","year":"2009","journal-title":"Current Opinion in Pharmacology"},{"key":"10.1016\/j.resp.2013.05.016_bib0175","doi-asserted-by":"crossref","first-page":"11159","DOI":"10.1073\/pnas.0402026101","article-title":"Evidence for defective energy homeostasis in amyotrophic lateral sclerosis: benefit of a high-energy diet in a transgenic mouse model","volume":"101","author":"Dupuis","year":"2004","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.resp.2013.05.016_bib0180","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1001\/archneur.1979.00500380044004","article-title":"Spirometry in amyotrophic lateral sclerosis","volume":"36","author":"Fallat","year":"1979","journal-title":"Archives of Neurology"},{"key":"10.1016\/j.resp.2013.05.016_bib0185","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1146\/annurev-physiol-040510-130049","article-title":"Understanding the rhythm of breathing: so near, yet so far","volume":"75","author":"Feldman","year":"2013","journal-title":"Annual Review of Physiology"},{"key":"10.1016\/j.resp.2013.05.016_bib0190","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1146\/annurev.neuro.26.041002.131103","article-title":"Breathing: rhythmicity, plasticity, chemosensitivity","volume":"26","author":"Feldman","year":"2003","journal-title":"Annual Review of Neuroscience"},{"key":"10.1016\/j.resp.2013.05.016_bib0195","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.expneurol.2003.10.004","article-title":"Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man","volume":"185","author":"Fischer","year":"2004","journal-title":"Experimental Neurology"},{"key":"10.1016\/j.resp.2013.05.016_bib0200","doi-asserted-by":"crossref","first-page":"2534","DOI":"10.1523\/JNEUROSCI.20-07-02534.2000","article-title":"Early and selective loss of neuromuscular synapse subtypes with low sprouting competence in motoneuron diseases","volume":"20","author":"Frey","year":"2000","journal-title":"The Journal of Neuroscience"},{"key":"10.1016\/j.resp.2013.05.016_bib0205","doi-asserted-by":"crossref","first-page":"379","DOI":"10.3109\/17482960903426543","article-title":"ALS with respiratory onset: clinical features and effects of non-invasive ventilation on the prognosis","volume":"11","author":"Gautier","year":"2010","journal-title":"Amyotrophic Lateral Sclerosis"},{"issue":"2","key":"10.1016\/j.resp.2013.05.016_bib0210","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/0006-8993(95)01111-0","article-title":"Direct evidence for the link between monoaminergic descending pathways and motor activity. I. A study with microdialysis probes implanted in the ventral funiculus of the spinal cord","volume":"704","author":"Gerin","year":"1995","journal-title":"Brain Research"},{"issue":"6","key":"10.1016\/j.resp.2013.05.016_bib0215","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1046\/j.0953-816x.2001.01484.x","article-title":"Differential regulation by exercise of BDNF and NT-3 in rat spinal cord and skeletal muscle","volume":"13","author":"G\u00f3mez-Pinilla","year":"2001","journal-title":"European Journal of Neuroscience"},{"issue":"5","key":"10.1016\/j.resp.2013.05.016_bib0220","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1152\/jn.00152.2002","article-title":"Voluntary exercise induces a BDNF-mediated mechanism that promotes neuroplasticity","volume":"88","author":"G\u00f3mez-Pinilla","year":"2002","journal-title":"Journal of Neurophysiology"},{"key":"10.1016\/j.resp.2013.05.016_bib0225","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1179\/016164104225013806","article-title":"Adaptive and maladaptive motor axonal sprouting in aging and motoneuron disease","volume":"26","author":"Gordon","year":"2004","journal-title":"Neurological Research"},{"key":"10.1016\/j.resp.2013.05.016_bib0230","first-page":"435","article-title":"Evaluation and management of respiratory muscle dysfunction in ALS","volume":"22","author":"Gregory","year":"2007","journal-title":"NeuroRehabilitation"},{"key":"10.1016\/j.resp.2013.05.016_bib0235","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.nbd.2004.01.017","article-title":"Local GDNF expression mediated by lentiviral vector protects facial nerve motoneurons but not spinal motoneurons in SOD1 (G93A) transgenic mice","volume":"16","author":"Guillot","year":"2004","journal-title":"Neurobiology of Disease"},{"key":"10.1016\/j.resp.2013.05.016_bib0240","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1126\/science.8209258","article-title":"Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation","volume":"264","author":"Gurney","year":"1994","journal-title":"Science"},{"key":"10.1016\/j.resp.2013.05.016_bib0245","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/s00415-010-5830-y","article-title":"Management of respiratory symptoms in ALS","volume":"258","author":"Hardiman","year":"2011","journal-title":"Journal of Neurology"},{"key":"10.1016\/j.resp.2013.05.016_bib0250","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1038\/nrneurol.2011.153","article-title":"Clinical diagnosis and management of amyotrophic lateral sclerosis","volume":"7","author":"Hardiman","year":"2011","journal-title":"Nature Reviews. Neurology"},{"key":"10.1016\/j.resp.2013.05.016_bib0255","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1111\/j.1440-1789.2007.00838.x","article-title":"Forme fruste or incipient form of widespread-type amyotrophic lateral sclerosis, or motor neuron disease with pallido-nigro-luysian atrophy? An autopsy case report","volume":"28","author":"Hashimoto","year":"2008","journal-title":"Neuropathology"},{"key":"10.1016\/j.resp.2013.05.016_bib0260","doi-asserted-by":"crossref","first-page":"8286","DOI":"10.1073\/pnas.1200912109","article-title":"Cumulative lesioning of respiratory interneurons disrupts and precludes motor rhythms in vitro","volume":"109","author":"Hayes","year":"2012","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.resp.2013.05.016_bib0265","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.nbd.2007.07.003","article-title":"Time course of preferential motor unit loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis","volume":"28","author":"Hegedus","year":"2007","journal-title":"Neurobiology of Disease"},{"key":"10.1016\/j.resp.2013.05.016_bib0270","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1002\/mus.21160","article-title":"Progressive motor unit loss in the G93A mouse model of amyotrophic lateral sclerosis is unaffected by gender","volume":"39","author":"Hegedus","year":"2009","journal-title":"Muscle and Nerve"},{"key":"10.1016\/j.resp.2013.05.016_bib0275","doi-asserted-by":"crossref","first-page":"3337","DOI":"10.1113\/jphysiol.2007.149286","article-title":"Preferential motor unit loss in the SOD1 G93A transgenic mouse model of amyotrophic lateral sclerosis","volume":"586","author":"Hegedus","year":"2008","journal-title":"Journal of Physiology"},{"key":"10.1016\/j.resp.2013.05.016_bib0280","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1152\/japplphysiol.01299.2011","article-title":"Volitional control of reflex cough","volume":"113","author":"Hegland","year":"2012","journal-title":"Journal of Applied Physiology"},{"key":"10.1016\/j.resp.2013.05.016_bib0285","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1073\/pnas.032539299","article-title":"Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS)","volume":"99","author":"Howland","year":"2002","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.resp.2013.05.016_bib0290","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1152\/jn.1987.58.1.105","article-title":"Electrical properties of phrenic motoneurons in the cat: correlation with inspiratory drive","volume":"58","author":"Jodkowski","year":"1987","journal-title":"Journal of Neurophysiology"},{"key":"10.1016\/j.resp.2013.05.016_bib0295","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1152\/jn.1988.60.2.687","article-title":"Repetitive firing properties of phrenic motoneurons in the cat","volume":"60","author":"Jodkowski","year":"1988","journal-title":"Journal of Neurophysiology"},{"key":"10.1016\/j.resp.2013.05.016_bib0300","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1038\/sj.embor.7400826","article-title":"The neurite outgrowth inhibitor Nogo-A promotes denervation in an amyotrophic lateral sclerosis model","volume":"7","author":"Jokic","year":"2006","journal-title":"EMBO Reports"},{"key":"10.1016\/j.resp.2013.05.016_bib0305","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1002\/ana.20420","article-title":"Nogo expression in muscle correlates with amyotrophic lateral sclerosis severity","volume":"57","author":"Jokic","year":"2005","journal-title":"Annals of Neurology"},{"key":"10.1016\/j.resp.2013.05.016_bib0310","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1146\/annurev.neuro.051508.135722","article-title":"Motor neuron diversity in development and disease","volume":"33","author":"Kanning","year":"2010","journal-title":"Annual Review of Neuroscience"},{"issue":"1","key":"10.1016\/j.resp.2013.05.016_bib0315","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/S0022-510X(99)00045-3","article-title":"Bipap improves survival and rate of pulmonary function decline in patients with ALS","volume":"164","author":"Kleopa","year":"1999","journal-title":"Journal of the Neurological Sciences"},{"key":"10.1016\/j.resp.2013.05.016_bib0320","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.jns.2010.10.030","article-title":"FALS with Gly72Ser mutation in SOD1 gene: report of a family including the first autopsy case","volume":"300","author":"Kobayashi","year":"2011","journal-title":"Journal of the Neurological Sciences"},{"key":"10.1016\/j.resp.2013.05.016_bib0325","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/0896-6273(93)90326-M","article-title":"Evidence that brain-derived neurotrophic factor is a trophic factor for motor neurons in vivo","volume":"10","author":"Koliatsos","year":"1993","journal-title":"Neuron"},{"key":"10.1016\/j.resp.2013.05.016_bib0330","first-page":"379657","article-title":"Neuromuscular junction protection for the potential treatment of amyotrophic lateral sclerosis","author":"Krakora","year":"2012","journal-title":"Neurology Research International"},{"key":"10.1016\/j.resp.2013.05.016_bib0335","first-page":"366","article-title":"Diagnosis and treatment of bulbar symptoms in amyotrophic lateral sclerosis. Nature clinical practice","volume":"4","author":"Kuhnlein","year":"2008","journal-title":"Neurology"},{"key":"10.1016\/j.resp.2013.05.016_bib0340","first-page":"871","article-title":"Respiratory effects of amyotrophic lateral sclerosis: problems and solutions","volume":"51","author":"Lechtzin","year":"2006","journal-title":"Respiratory Care"},{"key":"10.1016\/j.resp.2013.05.016_bib0345","first-page":"5","article-title":"Amyotrophic lateral sclerosis: evaluation and treatment of respiratory impairment. Amyotrophic lateral sclerosis and other motor neuron disorders: official publication of the World Federation of Neurology","volume":"3","author":"Lechtzin","year":"2002","journal-title":"Research Group on Motor Neuron Diseases"},{"key":"10.1016\/j.resp.2013.05.016_bib0350","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1080\/17482960701262392","article-title":"Early use of non-invasive ventilation prolongs survival in subjects with ALS","volume":"8","author":"Lechtzin","year":"2007","journal-title":"Amyotrophic Lateral Sclerosis"},{"key":"10.1016\/j.resp.2013.05.016_bib0355","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1002\/mus.10115","article-title":"Electromyography of sternocleidomastoid muscle in ALS: a prospective study","volume":"25","author":"Li","year":"2002","journal-title":"Muscle and Nerve"},{"key":"10.1016\/j.resp.2013.05.016_bib0360","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0304-3940(98)00434-0","article-title":"GDNF expression is increased in denervated human skeletal muscle","volume":"250","author":"Lie","year":"1998","journal-title":"Neuroscience Letters"},{"key":"10.1016\/j.resp.2013.05.016_bib0365","doi-asserted-by":"crossref","first-page":"133","DOI":"10.2307\/3579763","article-title":"Increased hydroxyl radical production and apoptosis in PC12 neuron cells expressing the gain-of-function mutant G93A SOD1 gene","volume":"151","author":"Liu","year":"1999","journal-title":"Radiation Research"},{"key":"10.1016\/j.resp.2013.05.016_bib0370","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.nbd.2005.06.019","article-title":"Degeneration of respiratory motor neurons in the SOD1 G93A transgenic rat model of ALS","volume":"21","author":"Llado","year":"2006","journal-title":"Neurobiology of Disease"},{"key":"10.1016\/j.resp.2013.05.016_bib0375","doi-asserted-by":"crossref","first-page":"3591","DOI":"10.1523\/JNEUROSCI.2908-11.2012","article-title":"Repetitive intermittent hypoxia induces respiratory and somatic motor recovery after chronic cervical spinal injury","volume":"32","author":"Lovett-Barr","year":"2012","journal-title":"The Journal of Neuroscience"},{"issue":"Suppl. 1","key":"10.1016\/j.resp.2013.05.016_bib0380","first-page":"S14L S20","article-title":"Problems and pitfalls in the diagnosis of ALS","volume":"165","author":"Ludolph","year":"1999","journal-title":"Journal of the Neurological Sciences"},{"key":"10.1016\/j.resp.2013.05.016_bib0385","doi-asserted-by":"crossref","first-page":"2000","DOI":"10.1093\/brain\/124.10.2000","article-title":"Respiratory muscle strength and ventilatory failure in amyotrophic lateral sclerosis","volume":"124","author":"Lyall","year":"2001","journal-title":"Brain"},{"key":"10.1016\/j.resp.2013.05.016_bib0390","series-title":"Skeletal Muscle: Form and Function","author":"MacIntosh","year":"2006"},{"key":"10.1016\/j.resp.2013.05.016_bib0395","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1007\/978-0-387-73693-8_39","article-title":"Respiratory long-term facilitation: too much or too little of a good thing?","volume":"605","author":"Mahamed","year":"2008","journal-title":"Advances in Experimental Medicine and Biology"},{"key":"10.1016\/j.resp.2013.05.016_bib0400","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.resp.2010.07.001","article-title":"Diaphragm motor unit recruitment in rats","volume":"173","author":"Mantilla","year":"2010","journal-title":"Respiratory Physiology & Neurobiology"},{"key":"10.1016\/j.resp.2013.05.016_bib0405","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/j.1600-0404.1995.tb01699.x","article-title":"Respiratory function deterioration is not time-linked with upper-limb onset in amyotrophic lateral sclerosis","volume":"92","author":"Marti-Fabregas","year":"1995","journal-title":"Acta Neurologica Scandinavica"},{"key":"10.1016\/j.resp.2013.05.016_bib0410","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1385\/NMM:9:1:17","article-title":"Energy intake and amyotrophic lateral sclerosis","volume":"9","author":"Mattson","year":"2007","journal-title":"Neuromolecular Medicine"},{"key":"10.1016\/j.resp.2013.05.016_bib0415","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1146\/annurev.neuro.26.043002.094919","article-title":"Epidemiology of neurodegeneration","volume":"26","author":"Mayeux","year":"2003","journal-title":"Annual Review of Neuroscience"},{"key":"10.1016\/j.resp.2013.05.016_bib0420","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1002\/(SICI)1521-1878(200001)22:1<6::AID-BIES3>3.0.CO;2-Q","article-title":"Unraveling the mechanism for respiratory rhythm generation","volume":"22","author":"McCrimmon","year":"2000","journal-title":"BioEssays"},{"key":"10.1016\/j.resp.2013.05.016_bib0425","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1038\/nn1517","article-title":"Sleep-disordered breathing after targeted ablation of preBotzinger complex neurons","volume":"8","author":"McKay","year":"2005","journal-title":"Nature Neuroscience"},{"key":"10.1016\/j.resp.2013.05.016_bib0430","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.jns.2006.05.059","article-title":"The cortico-diaphragmatic pathway involvement in amyotrophic lateral sclerosis: neurophysiological, respiratory and clinical considerations","volume":"251","author":"Miscio","year":"2006","journal-title":"Journal of the Neurological Sciences"},{"key":"10.1016\/j.resp.2013.05.016_bib0435","doi-asserted-by":"crossref","first-page":"2466","DOI":"10.1152\/jappl.2001.90.6.2466","article-title":"Invited review: intermittent hypoxia and respiratory plasticity","volume":"90","author":"Mitchell","year":"2001","journal-title":"Journal of Applied Physiology"},{"key":"10.1016\/j.resp.2013.05.016_bib0440","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.jns.2011.05.013","article-title":"Correlation of cerebral spinal fluid pH and HCO3\u2212 with disease progression in ALS","volume":"307","author":"Morimoto","year":"2011","journal-title":"Journal of the Neurological Sciences"},{"key":"10.1016\/j.resp.2013.05.016_bib0445","first-page":"93","article-title":"A 49-year-old man with progressive bulbar palsy and respiratory failure","volume":"50","author":"Motoi","year":"1998","journal-title":"No to shinkei"},{"key":"10.1016\/j.resp.2013.05.016_bib0450","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1212\/01.wnl.0000208957.88534.11","article-title":"The effect of noninvasive ventilation on ALS patients and their caregivers","volume":"66","author":"Mustfa","year":"2006","journal-title":"Neurology"},{"key":"10.1016\/j.resp.2013.05.016_bib0455","doi-asserted-by":"crossref","first-page":"9246","DOI":"10.1523\/JNEUROSCI.21-23-09246.2001","article-title":"Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: associated mutations develop motor neuron disease","volume":"21","author":"Nagai","year":"2001","journal-title":"The Journal of Neuroscience"},{"key":"10.1016\/j.resp.2013.05.016_bib0460","series-title":"Respiratory Motor Neuron Survival and Plasticity in a Rodent Model of Familial Amyotrophic Lateral Sclerosis","author":"Nashold","year":"2011"},{"key":"10.1016\/j.resp.2013.05.016_bib0465","doi-asserted-by":"crossref","first-page":"A1212","DOI":"10.1096\/fasebj.20.5.A1212-b","article-title":"Phrenic, but not hypoglossal, motor output is diminished in a rat model of amyotrophic lateral sclerosis (ALS)","volume":"20","author":"Nashold","year":"2006","journal-title":"FASEB Journal"},{"key":"10.1016\/j.resp.2013.05.016_bib0470","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1164\/rccm.201206-1072OC","article-title":"Intermittent hypoxia and stem cell implants preserve breathing capacity in a rodent model of amyotrophic lateral sclerosis","volume":"187","author":"Nichols","year":"2013","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"key":"10.1016\/j.resp.2013.05.016_bib0475","doi-asserted-by":"crossref","first-page":"799.9","DOI":"10.1096\/fasebj.24.1_supplement.799.9","article-title":"Enhanced phrenic but not XII long-term facilitation (LTF) following acute intermittent hypoxia (AIH) in a rat model of amyotrophic lateral sclerosis (ALS)","volume":"24","author":"Nichols","year":"2010","journal-title":"FASEB Journal"},{"key":"10.1016\/j.resp.2013.05.016_bib0480","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1002\/cne.21041","article-title":"Axotomy induces contrasting changes in calcium and calcium-binding proteins in oculomotor and hypoglossal nuclei of Balb\/c mice","volume":"499","author":"Obal","year":"2006","journal-title":"Journal of Comparative Neurology"},{"issue":"Suppl.","key":"10.1016\/j.resp.2013.05.016_bib0485","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/0022-510X(96)00087-1","article-title":"The quality of care and symptom control\u2014the effects on the terminal phase of ALS\/MND","volume":"139","author":"Oliver","year":"1996","journal-title":"Journal of the Neurological Sciences"},{"key":"10.1016\/j.resp.2013.05.016_bib0490","first-page":"355","article-title":"Eye movement in amyotrophic lateral sclerosis: a longitudinal study","volume":"4","author":"Palmowski","year":"1995","journal-title":"German Journal of Ophthalmology"},{"key":"10.1016\/j.resp.2013.05.016_bib0495","doi-asserted-by":"crossref","first-page":"392","DOI":"10.3349\/ymj.2010.51.3.392","article-title":"How respiratory muscle strength correlates with cough capacity in patients with respiratory muscle weakness","volume":"51","author":"Park","year":"2010","journal-title":"Yonsei Medical Journal"},{"key":"10.1016\/j.resp.2013.05.016_bib0500","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1083\/jcb.17.2.327","article-title":"An electron microscope study of denervation atrophy in red and white skeletal muscle fibers","volume":"17","author":"Pellegrino","year":"1963","journal-title":"Journal of Cell Biology"},{"key":"10.1016\/j.resp.2013.05.016_bib0505","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1016\/j.clinph.2009.08.025","article-title":"Changes of the phrenic nerve motor response in amyotrophic lateral sclerosis: longitudinal study","volume":"120","author":"Pinto","year":"2009","journal-title":"Clinical Neurophysiology"},{"key":"10.1016\/j.resp.2013.05.016_bib0510","first-page":"505","article-title":"Do bulbar-onset amyotrophic lateral sclerosis patients have an earlier respiratory involvement than spinal-onset amyotrophic lateral sclerosis patients?","volume":"43","author":"Pinto","year":"2007","journal-title":"Europa Medicophysica"},{"issue":"1\u20132","key":"10.1016\/j.resp.2013.05.016_bib0515","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0022-510X(99)00218-X","article-title":"Can amyotrophic lateral sclerosis patients with respiratory insufficiency exercise?","volume":"169","author":"Pinto","year":"1999","journal-title":"Journal of the Neurological Sciences"},{"key":"10.1016\/j.resp.2013.05.016_bib0520","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1002\/ana.21122","article-title":"Muscle Nogo-A expression is a prognostic marker in lower motor neuron syndromes","volume":"62","author":"Pradat","year":"2007","journal-title":"Annals of Neurology"},{"key":"10.1016\/j.resp.2013.05.016_bib0525","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.pmr.2008.04.003","article-title":"Glial cells in ALS: the missing link?","volume":"19","author":"Raibon","year":"2008","journal-title":"Physical Medicine and Rehabilitation Clinics of North America"},{"issue":"Pt 3","key":"10.1016\/j.resp.2013.05.016_bib0530","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1111\/j.1469-7793.1998.895bs.x","article-title":"Selective lesioning of the cat pre-Botzinger complex in vivo eliminates breathing but not gasping","volume":"507","author":"Ramirez","year":"1998","journal-title":"Journal of Physiology"},{"key":"10.1016\/j.resp.2013.05.016_bib0535","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1080\/10790268.2010.11689714","article-title":"Physiotherapy secretion removal techniques in people with spinal cord injury: a systematic review","volume":"33","author":"Reid","year":"2010","journal-title":"The Journal of Spinal Cord Medicine"},{"key":"10.1016\/j.resp.2013.05.016_bib0540","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1146\/annurev.physiol.60.1.385","article-title":"PreBotzinger complex and pacemaker neurons: hypothesized site and kernel for respiratory rhythm generation","volume":"60","author":"Rekling","year":"1998","journal-title":"Annual Review of Physiology"},{"key":"10.1016\/j.resp.2013.05.016_bib0545","doi-asserted-by":"crossref","first-page":"RC113","DOI":"10.1523\/JNEUROSCI.20-23-j0003.2000","article-title":"Electrical coupling and excitatory synaptic transmission between rhythmogenic respiratory neurons in the preBotzinger complex","volume":"20","author":"Rekling","year":"2000","journal-title":"The Journal of Neuroscience"},{"key":"10.1016\/j.resp.2013.05.016_bib0550","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/362059a0","article-title":"Mutations in Cu\/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis","volume":"362","author":"Rosen","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.resp.2013.05.016_bib0555","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.expneurol.2012.01.027","article-title":"In vivo intermittent hypoxia elicits enhanced expansion and neuronal differentiation in cultured neural progenitors","volume":"235","author":"Ross","year":"2012","journal-title":"Experimental Neurology"},{"issue":"Suppl. 1","key":"10.1016\/j.resp.2013.05.016_bib0560","first-page":"S3L S9","article-title":"Current hypotheses for the underlying biology of amyotrophic lateral sclerosis","volume":"65","author":"Rothstein","year":"2009","journal-title":"Annals of Neurology"},{"key":"10.1016\/j.resp.2013.05.016_bib0565","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0006-8993(01)02288-0","article-title":"A possible role for BDNF, NT-4 and TrkB in the spinal cord and muscle of rat subjected to mechanical overload, bupivacaine injection and axotomy","volume":"907","author":"Sakuma","year":"2001","journal-title":"Brain Research"},{"key":"10.1016\/j.resp.2013.05.016_bib0570","first-page":"201696","article-title":"The recent understanding of the neurotrophin's role in skeletal muscle adaptation","volume":"2011","author":"Sakuma","year":"2011","journal-title":"Journal of Biomedicine & Biotechnology"},{"key":"10.1016\/j.resp.2013.05.016_bib0575","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.brainres.2006.01.129","article-title":"Parvalbumin and calbindin D-28k immunoreactivity in transgenic mice with a G93A mutant SOD1 gene","volume":"1083","author":"Sasaki","year":"2006","journal-title":"Brain Research"},{"key":"10.1016\/j.resp.2013.05.016_bib0580","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.expneurol.2012.05.020","article-title":"Repetitive acute intermittent hypoxia increases expression of proteins associated with plasticity in the phrenic motor nucleus","volume":"237","author":"Satriotomo","year":"2012","journal-title":"Experimental Neurology"},{"key":"10.1016\/j.resp.2013.05.016_bib0585","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1002\/(SICI)1097-4598(200004)23:4<617::AID-MUS22>3.0.CO;2-Y","article-title":"Dynamics of nuclei of muscle fibers and connective tissue cells in normal and denervated rat muscles","volume":"23","author":"Schmalbruch","year":"2000","journal-title":"Muscle and Nerve"},{"key":"10.1016\/j.resp.2013.05.016_bib0590","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1002\/mus.20450","article-title":"Pulmonary predictors of survival in amyotrophic lateral sclerosis: use in clinical trial design","volume":"33","author":"Schmidt","year":"2006","journal-title":"Muscle and Nerve"},{"key":"10.1016\/j.resp.2013.05.016_bib0595","doi-asserted-by":"crossref","first-page":"430","DOI":"10.3109\/17482968.2012.684214","article-title":"Safety, tolerability and pharmacodynamics of a skeletal muscle activator in amyotrophic lateral sclerosis","volume":"13","author":"Shefner","year":"2012","journal-title":"Amyotrophic Lateral Sclerosis"},{"key":"10.1016\/j.resp.2013.05.016_bib0600","doi-asserted-by":"crossref","first-page":"57","DOI":"10.3109\/17482960903207385","article-title":"Electrophysiological assessment of corticorespiratory pathway function in amyotrophic lateral sclerosis","volume":"11","author":"Shimizu","year":"2010","journal-title":"Amyotrophic Lateral Sclerosis"},{"key":"10.1016\/j.resp.2013.05.016_bib0605","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/S0272-5231(21)00958-8","article-title":"Physiological effects of diaphragm muscle denervation and disuse","volume":"15","author":"Sieck","year":"1994","journal-title":"Clinics in Chest Medicine"},{"key":"10.1016\/j.resp.2013.05.016_bib0610","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1034\/j.1399-3003.2000.15b19.x","article-title":"Diaphragmatic dysfunction and dyspnoea in amyotrophic lateral sclerosis","volume":"15","author":"Similowski","year":"2000","journal-title":"The European Respiratory Journal"},{"key":"10.1016\/j.resp.2013.05.016_bib0615","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1056\/NEJM198705073161906","article-title":"Practical problems in the respiratory care of patients with muscular dystrophy","volume":"316","author":"Smith","year":"1987","journal-title":"The New England Journal of Medicine"},{"key":"10.1016\/j.resp.2013.05.016_bib0620","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.bbr.2010.03.007","article-title":"Measures of bulbar and spinal motor function, muscle innervation, and mitochondrial function in ALS rats","volume":"211","author":"Smittkamp","year":"2010","journal-title":"Behavioural Brain Research"},{"key":"10.1016\/j.resp.2013.05.016_bib0625","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0022-510X(01)00621-9","article-title":"Electromyography of respiratory muscles in amyotrophic lateral sclerosis","volume":"191","author":"Stewart","year":"2001","journal-title":"Journal of the Neurological Sciences"},{"key":"10.1016\/j.resp.2013.05.016_bib0630","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1212\/WNL.23.7.714","article-title":"Normal and denervated muscle. A morphometric study of fine structure","volume":"23","author":"Stonnington","year":"1973","journal-title":"Neurology"},{"key":"10.1016\/j.resp.2013.05.016_bib0635","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1523\/JNEUROSCI.04-01-00070.1984","article-title":"Mobility of extrajunctional acetylcholine receptors on denervated adult muscle fibers","volume":"4","author":"Stya","year":"1984","journal-title":"The Journal of Neuroscience"},{"key":"10.1016\/j.resp.2013.05.016_bib0640","first-page":"931","article-title":"An autopsy case of amyotrophic lateral sclerosis with concomitant Alzheimer's and incidental Lewy body diseases","volume":"48","author":"Su","year":"1996","journal-title":"No to shinkei"},{"key":"10.1016\/j.resp.2013.05.016_bib0645","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1136\/jnnp.13.3.159","article-title":"Denervation changes in mammalian striated muscle","volume":"13","author":"Sunderland","year":"1950","journal-title":"Journal of Neurology, Neurosurgery, and Psychiatry"},{"key":"10.1016\/j.resp.2013.05.016_bib0650","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.1038\/mt.2008.197","article-title":"Direct muscle delivery of GDNF with human mesenchymal stem cells improves motor neuron survival and function in a rat model of familial ALS","volume":"16","author":"Suzuki","year":"2008","journal-title":"Molecular Therapy"},{"key":"10.1016\/j.resp.2013.05.016_bib0655","first-page":"87","article-title":"Assessment of pulmonary function in amyotrophic lateral sclerosis","volume":"51","author":"Talakad","year":"2009","journal-title":"The Indian Journal of Chest Diseases & Allied Sciences"},{"key":"10.1016\/j.resp.2013.05.016_bib0660","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1152\/japplphysiol.00193.2006","article-title":"Respiratory impairment in a mouse model of amyotrophic lateral sclerosis","volume":"102","author":"Tankersley","year":"2007","journal-title":"Journal of Applied Physiology"},{"key":"10.1016\/j.resp.2013.05.016_bib0665","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1177\/1545968311412055","article-title":"Exposure to acute intermittent hypoxia augments somatic motor function in humans with incomplete spinal cord injury","volume":"26","author":"Trumbower","year":"2012","journal-title":"Neurorehabilitation and Neural Repair"},{"key":"10.1016\/j.resp.2013.05.016_bib0670","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1046\/j.1440-1789.2002.00451.x","article-title":"Sporadic amyotrophic lateral sclerosis with circumscribed temporal atrophy: a report of an autopsy case without dementia and with ubiquitinated intraneuronal inclusions","volume":"22","author":"Tsuchiya","year":"2002","journal-title":"Neuropathology"},{"key":"10.1016\/j.resp.2013.05.016_bib0675","doi-asserted-by":"crossref","first-page":"245","DOI":"10.3109\/17482968.2011.636050","article-title":"Does interneuronal dysfunction contribute to neurodegeneration in amyotrophic lateral sclerosis?","volume":"13","author":"Turner","year":"2012","journal-title":"Amyotrophic Lateral Sclerosis"},{"key":"10.1016\/j.resp.2013.05.016_bib0680","doi-asserted-by":"crossref","first-page":"e34640","DOI":"10.1371\/journal.pone.0034640","article-title":"Shared resistance to aging and ALS in neuromuscular junctions of specific muscles","volume":"7","author":"Valdez","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.resp.2013.05.016_bib0685","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1183\/09031936.97.10071614","article-title":"Breathing pattern and respiratory mechanics in patients with amyotrophic lateral sclerosis","volume":"10","author":"Vitacca","year":"1997","journal-title":"The European Respiratory Journal"},{"key":"10.1016\/j.resp.2013.05.016_bib0690","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/0034-5687(82)90021-4","article-title":"Prolonged post-stimulus inhibition of breathing following stimulation of afferents from muscle","volume":"50","author":"Waldrop","year":"1982","journal-title":"Respiration Physiology"},{"key":"10.1016\/j.resp.2013.05.016_bib0695","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1016\/0896-6273(95)90259-7","article-title":"An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria","volume":"14","author":"Wong","year":"1995","journal-title":"Neuron"},{"key":"10.1016\/j.resp.2013.05.016_bib0700","doi-asserted-by":"crossref","first-page":"345","DOI":"10.3109\/17482968.2011.582647","article-title":"Upper trapezius electromyography aids in the early diagnosis of bulbar involvement in amyotrophic lateral sclerosis","volume":"12","author":"Xu","year":"2011","journal-title":"Amyotrophic Lateral Sclerosis"}],"container-title":["Respiratory Physiology &amp; Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569904813001560?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569904813001560?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T22:32:52Z","timestamp":1761604372000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1569904813001560"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11]]},"references-count":140,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["S1569904813001560"],"URL":"https:\/\/doi.org\/10.1016\/j.resp.2013.05.016","relation":{},"ISSN":["1569-9048"],"issn-type":[{"value":"1569-9048","type":"print"}],"subject":[],"published":{"date-parts":[[2013,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ventilatory control in ALS","name":"articletitle","label":"Article Title"},{"value":"Respiratory Physiology & Neurobiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.resp.2013.05.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}