{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T22:42:45Z","timestamp":1761604965042,"version":"build-2065373602"},"reference-count":38,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Physiology & Neurobiology"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1016\/j.resp.2017.11.011","type":"journal-article","created":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T00:15:45Z","timestamp":1512519345000},"page":"43-47","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Breathing disturbances in a model of Rett syndrome: A potential involvement of the glycine receptor \u03b13 subunit?"],"prefix":"10.1016","volume":"248","author":[{"given":"Guillaume","family":"Mesuret","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Dannenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauricio","family":"Arnoldt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anja-Annett","family":"Gr\u00fctzner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus","family":"Niebert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Swen","family":"H\u00fclsmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.resp.2017.11.011_bib0005","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1038\/13810","article-title":"Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2","volume":"23","author":"Amir","year":"1999","journal-title":"Nat. Genet."},{"issue":"3","key":"10.1016\/j.resp.2017.11.011_bib0010","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/0034-5687(70)90056-3","article-title":"Control of breathing in experimental anemia","volume":"10","author":"Bartlett","year":"1970","journal-title":"Respir. Physiol."},{"issue":"13","key":"10.1016\/j.resp.2017.11.011_bib0015","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1093\/hmg\/ddp181","article-title":"Mouse models of MeCP2 disorders share gene expression changes in the cerebellum and hypothalamus","volume":"18","author":"Ben-Shachar","year":"2009","journal-title":"Hum. Mol. Genet."},{"issue":"4","key":"10.1016\/j.resp.2017.11.011_bib0020","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1523\/JNEUROSCI.23-04-01099.2003","article-title":"Dynamic modulation of inspiratory drive currents by protein kinase A and protein phosphatases in functionally active motoneurons","volume":"23","author":"Bocchiaro","year":"2003","journal-title":"J. Neurosci."},{"issue":"7","key":"10.1016\/j.resp.2017.11.011_bib0025","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1023\/A:1018525222826","article-title":"Comparative studies on mammalian Muller (retinal glial) cells","volume":"26","author":"Chao","year":"1997","journal-title":"J. Neurocytol."},{"issue":"7321","key":"10.1016\/j.resp.2017.11.011_bib0030","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1038\/nature09582","article-title":"Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes","volume":"468","author":"Chao","year":"2010","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.resp.2017.11.011_bib0035","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1542\/peds.16.1.81","article-title":"A barometric method for measuring ventilation in newborn infants","volume":"16","author":"Drorbaugh","year":"1955","journal-title":"Pediatrics"},{"issue":"1","key":"10.1016\/j.resp.2017.11.011_bib0040","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1055\/s-2002-23598","article-title":"MECP2 mutation in a boy with severe neonatal encephalopathy: clinical, neuropathological and molecular findings","volume":"33","author":"Geerdink","year":"2002","journal-title":"Neuropediatrics"},{"issue":"3","key":"10.1016\/j.resp.2017.11.011_bib0045","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1038\/85899","article-title":"A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome","volume":"27","author":"Guy","year":"2001","journal-title":"Nat. Genet."},{"key":"10.1016\/j.resp.2017.11.011_bib0050","doi-asserted-by":"crossref","first-page":"385","DOI":"10.3389\/fphys.2016.00385","article-title":"GlyT2-dependent preservation of MECP2-expression in inhibitory neurons improves early respiratory symptoms but does not rescue survival in a mouse model of Rett syndrome","volume":"7","author":"H\u00fclsmann","year":"2016","journal-title":"Front. Physiol."},{"issue":"5672","key":"10.1016\/j.resp.2017.11.011_bib0055","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1126\/science.1094925","article-title":"GlyR alpha3: an essential target for spinal PGE2-mediated inflammatory pain sensitization","volume":"304","author":"Harvey","year":"2004","journal-title":"Science"},{"issue":"6","key":"10.1016\/j.resp.2017.11.011_bib0060","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1007\/s00702-003-0822-z","article-title":"Rett syndrome \u2212 an update","volume":"110","author":"Jellinger","year":"2003","journal-title":"J. Neural. Transm. (Vienna)"},{"issue":"1","key":"10.1016\/j.resp.2017.11.011_bib0065","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1136\/adc.85.1.29","article-title":"Characterisation of breathing and associated central autonomic dysfunction in the Rett disorder","volume":"85","author":"Julu","year":"2001","journal-title":"Arch. Dis. Child."},{"issue":"1","key":"10.1016\/j.resp.2017.11.011_bib0070","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1212\/01.wnl.0000223318.28938.45","article-title":"Early progressive encephalopathy in boys and MECP2 mutations","volume":"67","author":"Kankirawatana","year":"2006","journal-title":"Neurology"},{"key":"10.1016\/j.resp.2017.11.011_bib0075","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neuroscience.2016.01.063","article-title":"Presynaptic facilitation of glycinergic mIPSC is reduced in mice lacking alpha3 glycine receptor subunits","volume":"320","author":"Kono","year":"2016","journal-title":"Neuroscience"},{"issue":"36","key":"10.1016\/j.resp.2017.11.011_bib0080","doi-asserted-by":"crossref","first-page":"22317","DOI":"10.1016\/S0021-9258(18)45707-9","article-title":"Identification and functional expression of a novel ligand binding subunit of the inhibitory glycine receptor","volume":"265","author":"Kuhse","year":"1990","journal-title":"J. Biol. Chem."},{"issue":"11","key":"10.1016\/j.resp.2017.11.011_bib0085","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S0165-6147(02)02138-7","article-title":"Modulation of glycine receptor function: a novel approach for therapeutic intervention at inhibitory synapses?","volume":"23","author":"Laube","year":"2002","journal-title":"Trends Pharmacol. Sci."},{"issue":"1","key":"10.1016\/j.resp.2017.11.011_bib0090","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1186\/s12864-016-2746-7","article-title":"Transcriptome analysis of human brain tissue identifies reduced expression of complement complex C1Q Genes in Rett syndrome","volume":"17","author":"Lin","year":"2016","journal-title":"BMC Genom."},{"issue":"0","key":"10.1016\/j.resp.2017.11.011_bib0095","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainres.2013.09.028","article-title":"Postnatal development of glycine receptor subunits alpha1, alpha2, alpha3, and beta immunoreactivity in multiple brain stem respiratory-related nuclear groups of the rat","volume":"1538","author":"Liu","year":"2013","journal-title":"Brain Res."},{"key":"10.1016\/j.resp.2017.11.011_bib0100","first-page":"43029","article-title":"Serotonin receptor 1A-modulated phosphorylation of glycine receptor alpha3 controls breathing in mice","author":"Manzke","year":"2010","journal-title":"J. Clin. Invest."},{"issue":"1","key":"10.1016\/j.resp.2017.11.011_bib0105","doi-asserted-by":"crossref","first-page":"e4315","DOI":"10.1371\/journal.pone.0004315","article-title":"The methyl-CpG binding proteins Mecp2, Mbd2 and Kaiso are dispensable for mouse embryogenesis, but play a redundant function in neural differentiation","volume":"4","author":"Martin Caballero","year":"2009","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/j.resp.2017.11.011_bib0110","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.braindev.2004.10.002","article-title":"Classic Rett syndrome in a boy with R133C mutation of MECP2","volume":"27","author":"Masuyama","year":"2005","journal-title":"Brain Dev."},{"issue":"1","key":"10.1016\/j.resp.2017.11.011_bib0115","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1152\/jn.00826.2007","article-title":"Early defects of GABAergic synapses in the brain stem of a MeCP2 mouse model of Rett syndrome","volume":"99","author":"Medrihan","year":"2008","journal-title":"J. Neurophysiol."},{"issue":"6","key":"10.1016\/j.resp.2017.11.011_bib0120","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/j.neuropharm.2011.01.002","article-title":"Epac-mediated cAMP-signalling in the mouse model of Rett Syndrome","volume":"60","author":"Mironov","year":"2011","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.resp.2017.11.011_bib0125","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.neuroscience.2017.01.041","article-title":"A computational model of the respiratory network challenged and optimized by data from optogenetic manipulation of glycinergic neurons","volume":"347","author":"Oku","year":"2017","journal-title":"Neuroscience"},{"issue":"10","key":"10.1016\/j.resp.2017.11.011_bib0130","doi-asserted-by":"crossref","first-page":"3377","DOI":"10.1007\/s10803-015-2519-1","article-title":"Brief report: systematic review of Rett syndrome in males","volume":"45","author":"Reichow","year":"2015","journal-title":"J. Autism Dev. Disord."},{"issue":"48","key":"10.1016\/j.resp.2017.11.011_bib0135","doi-asserted-by":"crossref","first-page":"17230","DOI":"10.1523\/JNEUROSCI.2951-12.2012","article-title":"Anxiety-related mechanisms of respiratory dysfunction in a mouse model of Rett syndrome","volume":"32","author":"Ren","year":"2012","journal-title":"J. Neurosci."},{"issue":"37","key":"10.1016\/j.resp.2017.11.011_bib0140","first-page":"723","article-title":"On a unusual brain atrophy syndrome in hyperammonemia in childhood","volume":"116","author":"Rett","year":"1966","journal-title":"Wien. Med. Wochenschr."},{"issue":"12","key":"10.1016\/j.resp.2017.11.011_bib0145","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/j.molmed.2003.10.010","article-title":"Serotonin receptors: guardians of stable breathing","volume":"9","author":"Richter","year":"2003","journal-title":"Trends Mol. Med."},{"issue":"2","key":"10.1016\/j.resp.2017.11.011_bib0150","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1111\/j.1399-0004.2008.01005.x","article-title":"Severe congenital encephalopathy caused by MECP2 null mutations in males: central hypoxia and reduced neuronal dendritic structure","volume":"74","author":"Schule","year":"2008","journal-title":"Clin. Genet."},{"issue":"Pt 2","key":"10.1016\/j.resp.2017.11.011_bib0155","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1113\/jphysiol.2002.031005","article-title":"Modulation of AMPA receptors by cAMP-dependent protein kinase in preBotzinger complex inspiratory neurons regulates respiratory rhythm in the rat","volume":"547","author":"Shao","year":"2003","journal-title":"J. Physiol."},{"issue":"Pt 3","key":"10.1016\/j.resp.2017.11.011_bib0160","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1113\/jphysiol.2006.119966","article-title":"Breathing dysfunctions associated with impaired control of postinspiratory activity in Mecp2-\/y knockout mice","volume":"579","author":"Stettner","year":"2007","journal-title":"J. Physiol."},{"issue":"50","key":"10.1016\/j.resp.2017.11.011_bib0165","doi-asserted-by":"crossref","first-page":"11521","DOI":"10.1523\/JNEUROSCI.4373-05.2005","article-title":"Mecp2 deficiency disrupts norepinephrine and respiratory systems in mice","volume":"25","author":"Viemari","year":"2005","journal-title":"J. Neurosci."},{"issue":"7","key":"10.1016\/j.resp.2017.11.011_bib0170","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1136\/jmg.2007.049452","article-title":"MECP2 mutations in males","volume":"44","author":"Villard","year":"2007","journal-title":"J. Med. Genet."},{"issue":"61","key":"10.1016\/j.resp.2017.11.011_bib0175","article-title":"Analysis of the serotonergic system in a mouse model of rett syndrome reveals unusual upregulation of serotonin receptor 5b","volume":"10","author":"Vogelgesang","year":"2017","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.resp.2017.11.011_bib0180","unstructured":"Vogelgesang, S. (2013). Identifying Target Genes related to Respiratory Network Dysfunction in a Mouse Model for the Rett Syndrome. Dr. rer. nat., Georg-August-Universit\u00e4t G\u00f6ttingen."},{"issue":"12","key":"10.1016\/j.resp.2017.11.011_bib0185","doi-asserted-by":"crossref","first-page":"e115444","DOI":"10.1371\/journal.pone.0115444","article-title":"Characterization of the MeCP2R168X knockin mouse model for Rett syndrome","volume":"9","author":"Wegener","year":"2014","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.resp.2017.11.011_bib0190","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1002\/cne.20349","article-title":"Glycinergic neurons expressing enhanced green fluorescent protein in bacterial artificial chromosome transgenic mice","volume":"482","author":"Zeilhofer","year":"2005","journal-title":"J. Comp. Neurol."}],"container-title":["Respiratory Physiology & Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569904817303427?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569904817303427?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T22:38:55Z","timestamp":1761604735000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1569904817303427"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":38,"alternative-id":["S1569904817303427"],"URL":"https:\/\/doi.org\/10.1016\/j.resp.2017.11.011","relation":{},"ISSN":["1569-9048"],"issn-type":[{"type":"print","value":"1569-9048"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Breathing disturbances in a model of Rett syndrome: A potential involvement of the glycine receptor \u03b13 subunit?","name":"articletitle","label":"Article Title"},{"value":"Respiratory Physiology & Neurobiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.resp.2017.11.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}