{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T03:59:16Z","timestamp":1777521556543,"version":"3.51.4"},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Physiology & Neurobiology"],"published-print":{"date-parts":[[2018,8]]},"DOI":"10.1016\/j.resp.2018.05.001","type":"journal-article","created":{"date-parts":[[2018,5,2]],"date-time":"2018-05-02T22:07:30Z","timestamp":1525298850000},"page":"64-72","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Cerebral oxygen availability during exercise in COPD patients with cognitive impairment"],"prefix":"10.1016","volume":"254","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0868-1096","authenticated-orcid":false,"given":"Vasileios","family":"Andrianopoulos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4830-7207","authenticated-orcid":false,"given":"Ioannis","family":"Vogiatzis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rainer","family":"Gloeckl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Bals","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rembert A.","family":"Koczulla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klaus","family":"Kenn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.resp.2018.05.001_bib0005","doi-asserted-by":"crossref","first-page":"R1473","DOI":"10.1152\/ajpregu.91008.2008","article-title":"Integration of cerebrovascular CO2 reactivity and chemoreflex control of breathing: mechanisms of regulation, measurement, and interpretation","volume":"296","author":"Ainslie","year":"2009","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.resp.2018.05.001_bib0010","doi-asserted-by":"crossref","first-page":"H976","DOI":"10.1152\/ajpheart.00639.2006","article-title":"Alterations in cerebral autoregulation and cerebral blood flow velocity during acute hypoxia: rest and exercise","volume":"292","author":"Ainslie","year":"2007","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.resp.2018.05.001_bib0015","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.hrtlng.2014.09.002","article-title":"COPD is associated with cognitive dysfunction and poor physical fitness in heart failure","volume":"44","author":"Alosco","year":"2015","journal-title":"Heart Lung"},{"key":"10.1016\/j.resp.2018.05.001_bib0020","series-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"American Psychiatric Association,","year":"2013"},{"key":"10.1016\/j.resp.2018.05.001_bib0025","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1183\/20734735.001417","article-title":"Cognitive impairment in COPD: should cognitive evaluation be part of respiratory assessment?","volume":"13","author":"Andrianopoulos","year":"2017","journal-title":"Breathe"},{"key":"10.1016\/j.resp.2018.05.001_bib0030","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1164\/rccm.200707-980OC","article-title":"Impaired flow-mediated dilation is associated with low pulmonary function and emphysema in ex-smokers: the Emphysema and Cancer Action Project (EMCAP) Study","volume":"176","author":"Barr","year":"2007","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.resp.2018.05.001_bib0035","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1183\/09031936.00066807","article-title":"Autonomic and cerebrovascular abnormalities in mild COPD are worsened by chronic smoking","volume":"32","author":"Bernardi","year":"2008","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.resp.2018.05.001_bib0040","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/s12880-016-0125-0","article-title":"Cognitive tasks and cerebral blood flow through anterior cerebral arteries: a study via functional transcranial Doppler ultrasound recordings","volume":"16","author":"Bleton","year":"2016","journal-title":"BMC Med. Imaging"},{"key":"10.1016\/j.resp.2018.05.001_bib0045","first-page":"111","article-title":"The telephone interview for cognitive status","volume":"1","author":"Brandt","year":"1988","journal-title":"Neuropsychiatry Neuropsychol. Behav. Neurol."},{"key":"10.1016\/j.resp.2018.05.001_bib0050","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1037\/a0017260","article-title":"Rapid cognitive screening of patients with substance use disorders","volume":"17","author":"Copersino","year":"2009","journal-title":"Exp. Clin. Psychopharmacol."},{"key":"10.1016\/j.resp.2018.05.001_bib0055","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1089\/ham.2016.0036","article-title":"Cognitive function and cerebral oxygenation during prolonged exercise under hypoxia in healthy young males","volume":"17","author":"Dobashi","year":"2016","journal-title":"High Alt. Med. Biol."},{"key":"10.1016\/j.resp.2018.05.001_bib0060","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1157\/13088030","article-title":"[Transcutaneous measurement of partial pressure of carbon dioxide and oxygen saturation: validation of the SenTec monitor]","volume":"42","author":"Domingo","year":"2006","journal-title":"Arch. Bronconeumol."},{"key":"10.1016\/j.resp.2018.05.001_bib0065","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1513\/pats.200708-142ET","article-title":"Cardiac disease in chronic obstructive pulmonary disease","volume":"5","author":"Falk","year":"2008","journal-title":"Proc. Am. Thorac. Soc."},{"key":"10.1016\/j.resp.2018.05.001_bib0070","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1136\/thx.2003.019588","article-title":"Association between chronic obstructive pulmonary disease and systemic inflammation: a systematic review and a meta-analysis","volume":"59","author":"Gan","year":"2004","journal-title":"Thorax"},{"key":"10.1016\/j.resp.2018.05.001_bib0075","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1152\/japplphysiol.01269.2009","article-title":"Near-infrared spectroscopy and indocyanine green derived blood flow index for noninvasive measurement of muscle perfusion during exercise","volume":"108","author":"Habazettl","year":"2010","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2018.05.001_bib0080","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1183\/09031936.00197211","article-title":"Decreased cerebrovascular response to CO2 in post-menopausal females with COPD: role of oxidative stress","volume":"40","author":"Hartmann","year":"2012","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.resp.2018.05.001_bib0085","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1186\/1471-2466-14-99","article-title":"Cerebrovascular responses to submaximal exercise in women with COPD","volume":"14","author":"Hartmann","year":"2014","journal-title":"BMC Pulm. Med."},{"key":"10.1016\/j.resp.2018.05.001_bib0090","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0022-3999(96)00216-4","article-title":"International experiences with the Hospital Anxiety and Depression Scale?a review of validation data and clinical results","volume":"42","author":"Herrmann","year":"1997","journal-title":"J. Psychosom. Res."},{"key":"10.1016\/j.resp.2018.05.001_bib0095","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1183\/09031936.00150314","article-title":"An official European Respiratory Society\/American Thoracic Society technical standard: field walking tests in chronic respiratory disease","volume":"44","author":"Holland","year":"2014","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.resp.2018.05.001_bib0100","first-page":"180","article-title":"Cognitive decline among patients with chronic obstructive pulmonary disease","author":"Hung","year":"2009","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.resp.2018.05.001_bib0105","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.rmed.2011.08.016","article-title":"Is chronic obstructive pulmonary disease associated with increased arterial stiffness?","volume":"106","author":"Janner","year":"2012","journal-title":"Respir. Med."},{"key":"10.1016\/j.resp.2018.05.001_bib0110","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/0001-6918(66)90004-7","article-title":"The Stroop color-word test: a review","volume":"25","author":"Jensen","year":"1966","journal-title":"Acta Psychol."},{"key":"10.1016\/j.resp.2018.05.001_bib0115","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1164\/ajrccm\/145.6.1321","article-title":"A self-complete measure of health status for chronic airflow limitation: the St. George\u2019s respiratory questionnaire","volume":"145","author":"Jones","year":"1992","journal-title":"Am. Rev. Respir. Dis."},{"key":"10.1016\/j.resp.2018.05.001_bib0120","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1183\/09031936.00102509","article-title":"Development and first validation of the COPD Assessment Test","volume":"34","author":"Jones","year":"2009","journal-title":"Eur. Respir. J."},{"issue":"1985","key":"10.1016\/j.resp.2018.05.001_bib0125","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1152\/japplphysiol.00106.2008","article-title":"How NIR is the future in blood flow monitoring?","volume":"104","author":"Kuebler","year":"2008","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2018.05.001_bib0130","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1097\/MCP.0b013e328341cead","article-title":"Is the aging process accelerated in chronic obstructive pulmonary disease?","volume":"17","author":"Lee","year":"2011","journal-title":"Curr. Opin. Pulm. Med."},{"key":"10.1016\/j.resp.2018.05.001_bib0135","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1111\/j.1440-1843.2008.01355.x","article-title":"Relationship between field walking tests and incremental cycle ergometry in COPD","volume":"13","author":"Luxton","year":"2008","journal-title":"Respirology"},{"key":"10.1016\/j.resp.2018.05.001_bib0140","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1007\/s11357-011-9258-9","article-title":"Aging blunts hyperventilation-induced hypocapnia and reduction in cerebral blood flow velocity during maximal exercise","volume":"34","author":"Marsden","year":"2012","journal-title":"Age (Dordr)"},{"key":"10.1016\/j.resp.2018.05.001_bib0145","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1002\/gps.1610","article-title":"The Addenbrooke's Cognitive Examination Revised (ACE-R): a brief cognitive test battery for dementia screening","volume":"21","author":"Mioshi","year":"2006","journal-title":"Int. J. Geriatr. Psychiatry"},{"key":"10.1016\/j.resp.2018.05.001_bib0150","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1176\/ajp.148.1.102","article-title":"Reliability of a standardized mini-Mental state examination compared with the traditional mini-mental state examination","volume":"148","author":"Molloy","year":"1991","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.resp.2018.05.001_bib0155","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/S0197-4580(00)00130-5","article-title":"Vascular and metabolic reserve in Alzheimer\u2019s disease","volume":"21","author":"Nagata","year":"2000","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.resp.2018.05.001_bib0160","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1111\/j.1532-5415.2005.53221.x","article-title":"The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment","volume":"53","author":"Nasreddine","year":"2005","journal-title":"J. Am. Geriatr. Soc."},{"issue":"1985","key":"10.1016\/j.resp.2018.05.001_bib0165","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1152\/japplphysiol.00573.2009","article-title":"Cerebral blood flow during exercise: mechanisms of regulation","volume":"107","author":"Ogoh","year":"2009","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2018.05.001_bib0170","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1113\/jphysiol.2005.095836","article-title":"The effect of changes in cardiac output on middle cerebral artery mean blood velocity at rest and during exercise","volume":"569","author":"Ogoh","year":"2005","journal-title":"J. Physiol."},{"key":"10.1016\/j.resp.2018.05.001_bib0175","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.resp.2015.10.005","article-title":"Effects of heart failure on cerebral blood flow in COPD: rest and exercise","volume":"221","author":"Oliveira","year":"2016","journal-title":"Respir. Physiol. Neurobiol."},{"key":"10.1016\/j.resp.2018.05.001_bib0180","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/BF02985621","article-title":"Brain perfusion abnormalities in chronic obstructive pulmonary disease: comparison with cognitive impairment","volume":"20","author":"Ortapamuk","year":"2006","journal-title":"Ann. Nucl. Med."},{"key":"10.1016\/j.resp.2018.05.001_bib0185","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.resp.2014.10.009","article-title":"Aerobic fitness influences cerebral oxygenation response to maximal exercise in healthy subjects","volume":"205","author":"Oussaidene","year":"2015","journal-title":"Respir. Physiol. Neurobiol."},{"key":"10.1016\/j.resp.2018.05.001_bib0190","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1038\/jcbfm.2009.188","article-title":"Cerebral blood flow response to functional activation","volume":"30","author":"Paulson","year":"2010","journal-title":"J. Cereb. Blood Flow Metab."},{"issue":"1985","key":"10.1016\/j.resp.2018.05.001_bib0195","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1152\/japplphysiol.90613.2008","article-title":"Human cerebral arteriovenous vasoactive exchange during alterations in arterial blood gases","volume":"105","author":"Peebles","year":"2008","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2018.05.001_bib0200","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1113\/EP085949","article-title":"Effect of ageing on hypoxic exercise cardiorespiratory, muscle and cerebral oxygenation responses in healthy humans","volume":"102","author":"Puthon","year":"2017","journal-title":"Exp. Physiol."},{"key":"10.1016\/j.resp.2018.05.001_bib0205","doi-asserted-by":"crossref","first-page":"765","DOI":"10.2165\/00007256-200737090-00002","article-title":"Regulation of cerebral blood flow during exercise","volume":"37","author":"Querido","year":"2007","journal-title":"Sports Med."},{"key":"10.1016\/j.resp.2018.05.001_bib0210","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1007\/s00134-005-0006-4","article-title":"Transcutaneous arterial carbon dioxide pressure monitoring in critically ill adult patients","volume":"32","author":"Rodriguez","year":"2006","journal-title":"Intensive Care Med."},{"key":"10.1016\/j.resp.2018.05.001_bib0215","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.pneurobio.2010.06.002","article-title":"Effects of incremental exercise on cerebral oxygenation measured by near-infrared spectroscopy: a systematic review","volume":"92","author":"Rooks","year":"2010","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.resp.2018.05.001_bib0220","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1002\/ana.20493","article-title":"Cerebral hypoperfusion and clinical onset of dementia: the Rotterdam Study","volume":"57","author":"Ruitenberg","year":"2005","journal-title":"Ann. Neurol."},{"issue":"1985","key":"10.1016\/j.resp.2018.05.001_bib0225","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1152\/japplphysiol.00853.2007","article-title":"Cerebral blood flow and metabolism during exercise: implications for fatigue","volume":"104","author":"Secher","year":"2008","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2018.05.001_bib0230","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1016\/j.mayocp.2013.08.012","article-title":"Chronic obstructive pulmonary disease and association with mild cognitive impairment: the Mayo Clinic Study of Aging","volume":"88","author":"Singh","year":"2013","journal-title":"Mayo Clin. Proc."},{"key":"10.1016\/j.resp.2018.05.001_bib0235","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1183\/09031936.00150414","article-title":"An official systematic review of the European Respiratory Society\/American Thoracic Society: measurement properties of field walking tests in chronic respiratory disease","volume":"44","author":"Singh","year":"2014","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.resp.2018.05.001_bib0240","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.ejcdt.2012.10.014","article-title":"Hormonal dysfunction in patients with chronic obstructive pulmonary disease","volume":"61","author":"Sobhy","year":"2012","journal-title":"Egypt J. Chest Dis. Tuberc."},{"key":"10.1016\/j.resp.2018.05.001_bib0245","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1159\/000187631","article-title":"Accuracy of transcutaneous carbon dioxide tension measurements during cardiopulmonary exercise testing","volume":"78","author":"Stege","year":"2009","journal-title":"Respiration"},{"key":"10.1016\/j.resp.2018.05.001_bib0250","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/978-1-4899-7678-9_9","article-title":"Influence of hypoxia on cerebral blood flow regulation in humans","volume":"903","author":"Steinback","year":"2016","journal-title":"Adv. Exp. Med. Biol."},{"issue":"1985","key":"10.1016\/j.resp.2018.05.001_bib0255","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1152\/japplphysiol.91475.2008","article-title":"Frontal and motor cortex oxygenation during maximal exercise in normoxia and hypoxia","volume":"106","author":"Subudhi","year":"2009","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2018.05.001_bib0260","doi-asserted-by":"crossref","first-page":"765","DOI":"10.3233\/JAD-132018","article-title":"Dynamic cerebral autoregulation and tissue oxygenation in amnestic mild cognitive impairment","volume":"41","author":"Tarumi","year":"2014","journal-title":"J. Alzheimer\u2019s Dis."},{"key":"10.1016\/j.resp.2018.05.001_bib0265","first-page":"263","article-title":"COPD and cognitive impairment: the role of hypoxemia and oxygen therapy","volume":"5","author":"Thakur","year":"2010","journal-title":"Int. J. Chron. Obstruct. Pulmon. Dis."},{"key":"10.1016\/j.resp.2018.05.001_bib0270","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1177\/0271678X16658662","article-title":"Reduced global brain metabolism but maintained vascular function in amnestic mild cognitive impairment","volume":"37","author":"Thomas","year":"2017","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.resp.2018.05.001_bib0275","doi-asserted-by":"crossref","first-page":"R903","DOI":"10.1152\/ajpregu.00555.2011","article-title":"Cerebral perturbations during exercise in hypoxia","volume":"302","author":"Verges","year":"2012","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.resp.2018.05.001_bib0280","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1378\/chest.11-3035","article-title":"Mild cognitive impairment in moderate to severe COPD: a preliminary study","volume":"142","author":"Villeneuve","year":"2012","journal-title":"Chest"},{"key":"10.1016\/j.resp.2018.05.001_bib0285","doi-asserted-by":"crossref","first-page":"634761","DOI":"10.1155\/2012\/634761","article-title":"Mechanisms of physical activity limitation in chronic lung diseases","volume":"2012","author":"Vogiatzis","year":"2012","journal-title":"Pulm Med."},{"key":"10.1016\/j.resp.2018.05.001_bib0290","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1183\/09031936.00016312","article-title":"Cerebral cortex oxygen delivery and exercise limitation in patients with COPD","volume":"41","author":"Vogiatzis","year":"2013","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.resp.2018.05.001_bib0295","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/0895-4356(93)90053-4","article-title":"The physical activity scale for the elderly (PASE): development and evaluation","volume":"46","author":"Washburn","year":"1993","journal-title":"J. Clin. Epidemiol."},{"key":"10.1016\/j.resp.2018.05.001_bib0300","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1113\/jphysiol.2013.268953","article-title":"Integrative regulation of human brain blood flow","volume":"592","author":"Willie","year":"2014","journal-title":"J. Physiol."},{"key":"10.1016\/j.resp.2018.05.001_bib0305","doi-asserted-by":"crossref","first-page":"365","DOI":"10.3389\/fphys.2012.00365","article-title":"pCO2 and pH regulation of cerebral blood flow","volume":"3","author":"Yoon","year":"2012","journal-title":"Front. Physiol."},{"key":"10.1016\/j.resp.2018.05.001_bib0310","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.mehy.2008.01.025","article-title":"Chronic hypoxia-hypercapnia influences cognitive function: a possible new model of cognitive dysfunction in chronic obstructive pulmonary disease","volume":"71","author":"Zheng","year":"2008","journal-title":"Med. Hypotheses"}],"container-title":["Respiratory Physiology & Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569904818301022?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569904818301022?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T22:39:41Z","timestamp":1761604781000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1569904818301022"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8]]},"references-count":62,"alternative-id":["S1569904818301022"],"URL":"https:\/\/doi.org\/10.1016\/j.resp.2018.05.001","relation":{},"ISSN":["1569-9048"],"issn-type":[{"value":"1569-9048","type":"print"}],"subject":[],"published":{"date-parts":[[2018,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cerebral oxygen availability during exercise in COPD patients with cognitive impairment","name":"articletitle","label":"Article Title"},{"value":"Respiratory Physiology & Neurobiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.resp.2018.05.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}