{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T05:12:54Z","timestamp":1781586774714,"version":"3.54.5"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Physiology &amp; Neurobiology"],"published-print":{"date-parts":[[2023,5]]},"DOI":"10.1016\/j.resp.2023.104024","type":"journal-article","created":{"date-parts":[[2023,1,31]],"date-time":"2023-01-31T02:46:32Z","timestamp":1675133192000},"page":"104024","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Targeted delivery of inhalable drug particles in the tracheobronchial tree model of a pediatric patient with bronchopneumonia: A numerical study"],"prefix":"10.1016","volume":"311","author":[{"given":"Jianwei","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaole","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Tao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baobin","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingguo","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.resp.2023.104024_bib1","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.jconrel.2017.11.036","article-title":"Inhalable particulate drug delivery systems for lung cancer therapy: Nanoparticles, microparticles, nanocomposites and nanoaggregates","volume":"269","author":"Abdelaziz","year":"2018","journal-title":"J. Control Release"},{"key":"10.1016\/j.resp.2023.104024_bib2","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1080\/17425247.2018.1547280","article-title":"Lung cancer: active therapeutic targeting and inhalational nanoproduct design","volume":"15","author":"Alhajj","year":"2018","journal-title":"Expert Opin. Drug Del."},{"key":"10.1016\/j.resp.2023.104024_bib3","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S1526-0542(12)70124-0","article-title":"Deposition of small particles in the developing lung","volume":"13","author":"Amirav","year":"2012","journal-title":"Paediatr. Respir. Rev."},{"key":"10.1016\/j.resp.2023.104024_bib4","doi-asserted-by":"crossref","first-page":"2002103","DOI":"10.1002\/adhm.202002103","article-title":"Fast stereolithography printing of large-scale biocompatible hydrogel models","volume":"10","author":"Anandakrishnan","year":"2021","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.resp.2023.104024_bib5","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1001\/archsurg.1973.01350130051011","article-title":"Aspiration pneumonia. Clinical outcome following documented aspiration","volume":"106","author":"Cameron","year":"1973","journal-title":"Arch. Surg."},{"key":"10.1016\/j.resp.2023.104024_bib6","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.powtec.2011.10.034","article-title":"Study on gas\/solid flow in an obstructed pulmonary airway with transient flow based on CFD\u2013DPM approach","volume":"217","author":"Chen","year":"2012","journal-title":"Powder Technol."},{"key":"10.1016\/j.resp.2023.104024_bib7","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.powtec.2017.09.050","article-title":"Numerical investigation of particle deposition in a triple bifurcation airway due to gravitational sedimentation and inertial impaction","volume":"323","author":"Chen","year":"2018","journal-title":"Powder Technol."},{"key":"10.1016\/j.resp.2023.104024_bib8","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1007\/BF03256660","article-title":"Antibiotic treatment of multidrug-resistant organisms in cystic fibrosis","volume":"2","author":"Conway","year":"2003","journal-title":"Am. J. Respir. Med"},{"key":"10.1016\/j.resp.2023.104024_bib9","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1089\/jamp.2011.0916","article-title":"Aerosol deposition in health and disease","volume":"25","author":"Darquenne","year":"2012","journal-title":"J. Aerosol Med Pulm. Del."},{"key":"10.1016\/j.resp.2023.104024_bib10","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1016\/j.medengphy.2007.11.002","article-title":"Flow analyses in the lower airways: patient-specific model and boundary conditions","volume":"30","author":"De Backer","year":"2008","journal-title":"Med Eng. Phys."},{"key":"10.1016\/j.resp.2023.104024_bib11","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.scitotenv.2017.08.240","article-title":"Particle deposition in tracheobronchial airways of an infant, child and adult","volume":"612","author":"Deng","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.resp.2023.104024_bib12","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.ijpharm.2013.02.031","article-title":"Inhaled proteins: challenges and perspectives","volume":"447","author":"Depreter","year":"2013","journal-title":"Int J. Pharm."},{"key":"10.1016\/j.resp.2023.104024_bib13","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1111\/j.1399-6576.2006.00943.x","article-title":"Comparison of tracheal tube cuff diameters with internal transverse diameters of the trachea in children","volume":"50","author":"Dullenkopf","year":"2006","journal-title":"Acta Anaesthesiol. Scand."},{"key":"10.1016\/j.resp.2023.104024_bib14","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/s11095-020-02923-8","article-title":"CFD guided optimization of nose-to-lung aerosol delivery in adults: effects of inhalation waveforms and synchronized aerosol delivery","volume":"37","author":"Dutta","year":"2020","journal-title":"Pharm. Res"},{"key":"10.1016\/j.resp.2023.104024_bib15","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.3390\/pharmaceutics13071077","article-title":"Inhalation delivery for the treatment and prevention of COVID-19 infection","volume":"13","author":"Eedara","year":"2021","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.resp.2023.104024_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jaerosci.2014.01.003","article-title":"Micron-particle transport, interactions and deposition in triple lung-airway bifurcations using a novel modeling approach","volume":"71","author":"Feng","year":"2014","journal-title":"J. Aerosol Sci."},{"key":"10.1016\/j.resp.2023.104024_bib17","article-title":"An in silico investigation of a lobe-specific targeted pulmonary drug delivery method","author":"Feng","year":"2018","journal-title":"Des. Med. Devices Conf."},{"key":"10.1016\/j.resp.2023.104024_bib18","series-title":"The Mechanics of Inhaled Pharmaceutical Aerosols: an Introduction","author":"Finlay","year":"2001"},{"key":"10.1016\/j.resp.2023.104024_bib19","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1183\/09031936.01.00213501","article-title":"Imaging of pneumonia: trends and algorithms","volume":"18","author":"Franquet","year":"2001","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.resp.2023.104024_bib20","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1097\/RTI.0000000000000347","article-title":"Imaging of community-acquired pneumonia","volume":"33","author":"Franquet","year":"2018","journal-title":"J. Thorac. Imaging"},{"key":"10.1016\/j.resp.2023.104024_bib21","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1016\/S1473-3099(18)30310-4","article-title":"Estimates of the global, regional, and national morbidity, mortality, and aetiologies of lower respiratory infections in 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016","volume":"18","author":"GBD 2016 Lower Respiratory Infections Collaborators","year":"2018","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.resp.2023.104024_bib22","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1089\/jamp.2022.0016","article-title":"Suitability of bronchoscopic spraying for fluid deposition in lower sirway tegions: fluorescence analysis on a transparent in vitro airway model","volume":"35","author":"Gurzing","year":"2022","journal-title":"J. Aerosol Med Pulm. Drug Deliv."},{"key":"10.1016\/j.resp.2023.104024_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.resp.2019.103311","article-title":"Obstructions in the lower airways lead to altered airflow patterns in the central airway","volume":"272","author":"Hariprasad","year":"2020","journal-title":"Respir. Physiol. Neurobiol."},{"key":"10.1016\/j.resp.2023.104024_bib24","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1007\/s11095-010-0165-z","article-title":"Evaluation of enhanced condensational growth (ECG) for controlled respiratory drug delivery in a mouth-throat and upper tracheobronchial model","volume":"27","author":"Hindle","year":"2010","journal-title":"Pharm. Res"},{"key":"10.1016\/j.resp.2023.104024_bib25","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.jaerosci.2011.05.007","article-title":"Modelling inhaled particle deposition in the human lung\u2014A review","volume":"42","author":"Hofmann","year":"2011","journal-title":"J. Aerosol Sci."},{"key":"10.1016\/j.resp.2023.104024_bib26","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/j.powtec.2018.11.095","article-title":"Numerical investigation of deposition mechanism in three mouth\u2013throat models","volume":"378","author":"Huang","year":"2021","journal-title":"Powder Technol."},{"key":"10.1016\/j.resp.2023.104024_bib27","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0092-8674(02)00625-6","article-title":"Apoptosis: A link between cancer genetics and chemotherapy","volume":"108","author":"Johnstone","year":"2002","journal-title":"Cell"},{"key":"10.1016\/j.resp.2023.104024_bib28","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1089\/jamp.2015.1271","article-title":"Computational models of inhalation therapy in early childhood: Therapeutic aerosols in the developing acinus","volume":"29","author":"Katan","year":"2016","journal-title":"J. Aerosol Med Pulm. Del."},{"key":"10.1016\/j.resp.2023.104024_bib29","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1080\/027868299304255","article-title":"Deposition characteristics of aerosol particles in sequentially bifurcating airway models","volume":"31","author":"Kim","year":"1999","journal-title":"Aerosol Sci. Tech."},{"key":"10.1016\/j.resp.2023.104024_bib30","doi-asserted-by":"crossref","first-page":"11530","DOI":"10.1073\/pnas.1512613112","article-title":"Targeted delivery of liquid microvolumes into the lung","volume":"112","author":"Kim","year":"2015","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.resp.2023.104024_bib31","doi-asserted-by":"crossref","first-page":"13082","DOI":"10.1038\/s41598-017-13280-9","article-title":"Controlled delivery and minimally invasive imaging of stem cells in the lung","volume":"7","author":"Kim","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.resp.2023.104024_bib32","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1148\/radiol.12120385","article-title":"Chronic obstructive pulmonary disease: Lobe-based visual assessment of volumetric CT by using standard images-comparison with quantitative CT and pulmonary function test in the COPD gene study","volume":"266","author":"Kim","year":"2013","journal-title":"Radiology"},{"key":"10.1016\/j.resp.2023.104024_bib33","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1016\/j.jaerosci.2007.08.010","article-title":"Combined inertial and gravitational deposition of microparticles in small model airways of a human respiratory system","volume":"38","author":"Kleinstreuer","year":"2007","journal-title":"J. Aerosol Sci."},{"key":"10.1016\/j.resp.2023.104024_bib34","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1146\/annurev.bioeng.10.061807.160544","article-title":"Targeted drug-aerosol delivery in the human respiratory system","volume":"10","author":"Kleinstreuer","year":"2008","journal-title":"Annu Rev. Biomed. Eng."},{"key":"10.1016\/j.resp.2023.104024_bib35","doi-asserted-by":"crossref","first-page":"5578","DOI":"10.1016\/j.ijheatmasstransfer.2008.04.052","article-title":"A new methodology for targeting drug-aerosols in the human respiratory system","volume":"51","author":"Kleinstreuer","year":"2008","journal-title":"Int J. Heat. Mass Tran"},{"key":"10.1016\/j.resp.2023.104024_bib36","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.resp.2008.07.002","article-title":"Modeling airflow and particle transport\/deposition in pulmonary airways","volume":"163","author":"Kleinstreuer","year":"2008","journal-title":"Respir. Physiol. Neurobiol."},{"key":"10.1016\/j.resp.2023.104024_bib37","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1089\/jamp.2019.1564","article-title":"Realizing lobe-specific aerosol targeting in a 3D-printed in vitro lung model","volume":"34","author":"Kolewe","year":"2021","journal-title":"J. Aerosol. Med. Pulm. Del."},{"key":"10.1016\/j.resp.2023.104024_bib38","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1046\/j.1365-2125.2003.01892.x","article-title":"Pulmonary drug delivery. Part I: Physiological factors affecting therapeutic effectiveness of aerosolized medications","volume":"56","author":"Labiris","year":"2003","journal-title":"Br. J. Clin. Pharm."},{"key":"10.1016\/j.resp.2023.104024_bib39","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1097\/RLI.0000000000000672","article-title":"The clinical and chest CT features associated with severe and critical COVID-19 pneumonia","volume":"55","author":"Li","year":"2020","journal-title":"Invest Radio."},{"key":"10.1016\/j.resp.2023.104024_bib40","doi-asserted-by":"crossref","first-page":"2681","DOI":"10.1016\/j.jbiomech.2008.06.018","article-title":"Modeling the bifurcating flow in a CT-scanned human lung airway","volume":"41","author":"Luo","year":"2008","journal-title":"J. Biomech."},{"key":"10.1016\/j.resp.2023.104024_bib41","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.jaerosci.2008.04.003","article-title":"Enhanced deposition of high aspect ratio aerosols in small airway bifurcations using magnetic field alignment","volume":"39","author":"Martin","year":"2008","journal-title":"J. Aerosol Sci."},{"key":"10.1016\/j.resp.2023.104024_bib42","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1080\/08958370701821433","article-title":"Airway geometry models of children\u2019s lungs for use in dosimetry modeling","volume":"20","author":"M\u00e9nache","year":"2008","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.resp.2023.104024_bib43","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1017\/S0022112072001806","article-title":"An investigation of particle trajectories in two-phase flow systems","volume":"55","author":"Morsi","year":"1972","journal-title":"J. Fluid Mech."},{"key":"10.1016\/j.resp.2023.104024_bib44","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.resp.2017.06.005","article-title":"Numerical investigation of transient transport and deposition of microparticles under unsteady inspiratory flow in human upper airways","volume":"244","author":"Naseri","year":"2017","journal-title":"Respir. Physiol. Neurobiol."},{"key":"10.1016\/j.resp.2023.104024_bib45","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.jaerosci.2018.03.003","article-title":"Inertial and gravitational effects on aerosol deposition in the conducting airways","volume":"120","author":"Nicolaou","year":"2018","journal-title":"J. Aerosol Sci."},{"key":"10.1016\/j.resp.2023.104024_bib46","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1158\/1078-0432.CCR-06-1096","article-title":"Phase I study of inhaled doxorubicin for patients with metastatic tumors to the lungs","volume":"13","author":"Otterson","year":"2007","journal-title":"Clin. Cancer Res"},{"key":"10.1016\/j.resp.2023.104024_bib47","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1038\/nrd2153","article-title":"Inhaling medicines: delivering drugs to the body through the lungs","volume":"6","author":"Patton","year":"2007","journal-title":"Nat. Rev. Drug Disco"},{"key":"10.1016\/j.resp.2023.104024_bib48","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0034-5687(01)00270-5","article-title":"Methods for modeling particle deposition as a function of age","volume":"128","author":"Phalen","year":"2001","journal-title":"Respir. Physiol."},{"key":"10.1016\/j.resp.2023.104024_bib49","first-page":"367","article-title":"The inhalation of drugs: advantages and problems","volume":"50","author":"Rau","year":"2005","journal-title":"Resp. Care"},{"key":"10.1016\/j.resp.2023.104024_bib50","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1089\/jamp.2008.0684","article-title":"Feasibility and safety of targeted cisplatin delivery to a select lung lobe in dogs via the AeroProbe intracorporeal nebulization catheter","volume":"21","author":"Selting","year":"2008","journal-title":"J. Aerosol Med Pulm. Del."},{"key":"10.1016\/j.resp.2023.104024_bib51","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1007\/s10439-020-02623-9","article-title":"Breath hold facilitates targeted deposition of aerosolized droplets in a 3D printed bifurcating airway tree","volume":"49","author":"Sonnenberg","year":"2020","journal-title":"Ann. Biomed. Eng."},{"key":"10.1016\/j.resp.2023.104024_bib52","doi-asserted-by":"crossref","DOI":"10.1115\/1.4038896","article-title":"Assessing airflow sensitivity to healthy and diseased lung conditions in a computational fluid dynamics model validated in vitro","volume":"140","author":"Sul","year":"2018","journal-title":"J. Biomech. Eng."},{"key":"10.1016\/j.resp.2023.104024_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.powtec.2022.117520","article-title":"Targeted delivery of inhalable drug particles in a patient-specific tracheobronchial tree with moderate COVID-19: A numerical study","volume":"405","author":"Wang","year":"2022","journal-title":"Powder Technol."},{"key":"10.1016\/j.resp.2023.104024_bib54","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S1473-3099(01)00170-0","article-title":"Estimates of world-wide distribution of child deaths from acute respiratory infections","volume":"2","author":"Williams","year":"2002","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.resp.2023.104024_bib55","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.powtec.2019.08.007","article-title":"Numerical study on abnormal airflow patterns and particle deposition characteristics in the realistic HUA model with pharyngeal obstruction","volume":"356","author":"Yan","year":"2019","journal-title":"Powder Technol."},{"key":"10.1016\/j.resp.2023.104024_bib56","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1080\/02786826.2015.1101052","article-title":"Microparticle transport and deposition in the human oral airway: toward the smart spacer","volume":"49","author":"Yousefi","year":"2015","journal-title":"Aerosol Sci. Tech."},{"key":"10.1016\/j.resp.2023.104024_bib57","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.jaerosci.2004.08.006","article-title":"Comparison of micro- and nano-size particle depositions in a human upper airway model","volume":"36","author":"Zhang","year":"2004","journal-title":"J. Aerosol Sci."},{"key":"10.1016\/j.resp.2023.104024_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.compbiomed.2019.103532","article-title":"Glottis motion effects on the particle transport and deposition in a subject-specific mouth-to-trachea model: A CFPD study","volume":"116","author":"Zhao","year":"2020","journal-title":"Comput. Biol. Med"}],"container-title":["Respiratory Physiology &amp; Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569904823000125?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569904823000125?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T14:55:41Z","timestamp":1736434541000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1569904823000125"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":58,"alternative-id":["S1569904823000125"],"URL":"https:\/\/doi.org\/10.1016\/j.resp.2023.104024","relation":{},"ISSN":["1569-9048"],"issn-type":[{"value":"1569-9048","type":"print"}],"subject":[],"published":{"date-parts":[[2023,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Targeted delivery of inhalable drug particles in the tracheobronchial tree model of a pediatric patient with bronchopneumonia: A numerical study","name":"articletitle","label":"Article Title"},{"value":"Respiratory Physiology & Neurobiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.resp.2023.104024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"104024"}}