{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T22:51:34Z","timestamp":1761605494842,"version":"build-2065373602"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003193","name":"Ministry of Education Science Research and Sport of the Slovak Republic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003193","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006109","name":"Vedeck\u00e1 Grantov\u00e1 Agent\u00fara M\u0160VVa\u0160 SR a SAV","doi-asserted-by":"publisher","award":["1\/0072\/16","1\/0092\/20","1\/0275\/19"],"award-info":[{"award-number":["1\/0072\/16","1\/0092\/20","1\/0275\/19"]}],"id":[{"id":"10.13039\/501100006109","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Physiology & Neurobiology"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.resp.2023.104115","type":"journal-article","created":{"date-parts":[[2023,7,17]],"date-time":"2023-07-17T04:26:04Z","timestamp":1689567964000},"page":"104115","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Differential inhibition of cough by GABAA and GABAB receptor antagonists in the nucleus of the solitary tract in cats"],"prefix":"10.1016","volume":"315","author":[{"given":"Michal","family":"Simera","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7936-1869","authenticated-orcid":false,"given":"Marcel","family":"Veternik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lukas","family":"Martvon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zuzana","family":"Kotmanova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucia","family":"Cibulkova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan","family":"Poliacek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.resp.2023.104115_bib1","first-page":"H1236","article-title":"Non-NMDA and NMDA receptors in the synaptic pathway between area postrema and nucleus tractus solitarius","volume":"275","author":"Aylwin","year":"1998","journal-title":"Am. J. Physiol."},{"issue":"3","key":"10.1016\/j.resp.2023.104115_bib2","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1152\/jappl.1999.86.3.1017","article-title":"Influence of central antitussive drugs on the cough motor pattern","volume":"86","author":"Bolser","year":"1999","journal-title":"J. Appl. Physiol."},{"issue":"2","key":"10.1016\/j.resp.2023.104115_bib3","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.brainres.2005.07.019","article-title":"Ionotropic glutamate receptors mediate excitatory drive to caudal medullary expiratory neurons in the rabbit","volume":"1056","author":"Bongianni","year":"2005","journal-title":"Brain Res."},{"issue":"6","key":"10.1016\/j.resp.2023.104115_bib4","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.pupt.2004.09.008","article-title":"Plasticity of central mechanisms for cough","volume":"17","author":"Bonham","year":"2004","journal-title":"Pulm. Pharm. Ther."},{"issue":"3","key":"10.1016\/j.resp.2023.104115_bib5","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.resp.2006.02.010","article-title":"Plasticity of brainstem mechanisms of cough","volume":"152","author":"Bonham","year":"2006","journal-title":"Respir. Physiol. Neurobiol."},{"issue":"10","key":"10.1016\/j.resp.2023.104115_bib6","doi-asserted-by":"crossref","first-page":"3916","DOI":"10.1096\/fj.09-151068","article-title":"An essential component to brainstem cough gating identified in anesthetized guinea pigs","volume":"24","author":"Canning","year":"2010","journal-title":"FASEB J."},{"issue":"3","key":"10.1016\/j.resp.2023.104115_bib7","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.resp.2006.03.001","article-title":"Vagal afferent nerves regulating the cough reflex","volume":"152","author":"Canning","year":"2006","journal-title":"Respir. Physiol. Neurobiol."},{"issue":"4","key":"10.1016\/j.resp.2023.104115_bib8","first-page":"567","article-title":"Inflammation-induced plasticity of the afferent innervation of the airways","volume":"109","author":"Carr","year":"2001","journal-title":"Environ. Health Perspect."},{"issue":"2","key":"10.1016\/j.resp.2023.104115_bib9","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1113\/jphysiol.2004.076885","article-title":"Glutamate suppresses GABA release via presynaptic metabotropic glutamate receptors at baroreceptor neurones in rats","volume":"562","author":"Chen","year":"2005","journal-title":"J. Physiol."},{"year":"2003","series-title":"Cough: Causes, Mechanisms, and Therapy","author":"Chung","key":"10.1016\/j.resp.2023.104115_bib10"},{"key":"10.1016\/j.resp.2023.104115_bib11","doi-asserted-by":"crossref","DOI":"10.1002\/phy2.122","article-title":"Suppression of the cough reflex alpha2-adrenergic receptor agonist in the rabbit","volume":"1","author":"Cinelli","year":"2013","journal-title":"Physiol. Rep."},{"key":"10.1016\/j.resp.2023.104115_bib12","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.resp.2015.07.013","article-title":"The cough reflex is upregulated by lisinopril microinjected into the caudal nucleus tractus solitarii of the rabbit","volume":"219","author":"Cinelli","year":"2015","journal-title":"Respir. Physiol. Neurobiol."},{"issue":"3","key":"10.1016\/j.resp.2023.104115_bib13","doi-asserted-by":"crossref","DOI":"10.1152\/ajplung.00205.2016","article-title":"GABAA and glycine mediated inhibitory modulation of the cough reflex in the caudal nucleus tractus solitarii of the rabbit","volume":"311","author":"Cinelli","year":"2016","journal-title":"Am. J. Physiol. Lung. Cell. Mol. Physiol."},{"key":"10.1016\/j.resp.2023.104115_bib14","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.neuroscience.2012.05.053","article-title":"Cough-related neurons in the nucleus tractus solitarius of decerebrate cats","volume":"218","author":"Haji","year":"2012","journal-title":"Neuroscience"},{"key":"10.1016\/j.resp.2023.104115_bib15","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.peptides.2004.02.016","article-title":"Substance P in the baroreceptor reflex: 25 years","volume":"25","author":"Helke","year":"2004","journal-title":"Peptides"},{"key":"10.1016\/j.resp.2023.104115_bib16","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1111\/bph.12127","article-title":"Advantage of an antagonist: bicuculline and other GABA antagonists","volume":"169","author":"Johnston","year":"2013","journal-title":"Br. J. Pharm."},{"key":"10.1016\/j.resp.2023.104115_bib17","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.resp.2018.02.009","article-title":"GABA-ergic neurotransmission in the nucleus of the solitary tract modulates cough in the cat","volume":"257","author":"Kotmanova","year":"2018","journal-title":"Respir. Physiol. Neurobiol."},{"key":"10.1016\/j.resp.2023.104115_bib18","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1113\/jphysiol.1991.sp018506","article-title":"The medullary projections of afferent bronchopulmonary C-fibers in the cat as shown as shown by antidromic mapping","volume":"435","author":"Kubin","year":"1991","journal-title":"J. Physiol."},{"issue":"1\u20132","key":"10.1016\/j.resp.2023.104115_bib19","doi-asserted-by":"crossref","first-page":"91","DOI":"10.3109\/10641969509087057","article-title":"The tachycardia associated with the defense reaction involves activation of both GABAA and GABAB receptors in the nucleus tractus solitarii","volume":"17","author":"Kunos","year":"1995","journal-title":"Clin. Exp. Hypertens."},{"key":"10.1016\/j.resp.2023.104115_bib20","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1002\/syn.1096","article-title":"GABAergic neurotransmission at the nucleus tractus solitarii in the suppression of reflex bradycardia by parabrachial nucleus","volume":"42","author":"Len","year":"2001","journal-title":"Synapse"},{"issue":"2","key":"10.1016\/j.resp.2023.104115_bib21","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/0165-0270(88)90166-5","article-title":"Limitations of the technique of pressure microinjection of excitatory amino acids for evoking responses from localized regions of the CNS","volume":"26","author":"Lipski","year":"1988","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.resp.2023.104115_bib22","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1113\/jphysiol.1989.sp017545","article-title":"Kinetic properties of the GABAA receptor main conductance state of mouse spinal cord neurones in culture","volume":"419","author":"Macdonald","year":"1989","journal-title":"J. Physiol."},{"issue":"1\u20132","key":"10.1016\/j.resp.2023.104115_bib23","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.autneu.2010.08.003","article-title":"Important GABAergic mechanism within the NTS and the control of sympathetic baroreflex in SHR","volume":"159","author":"Moreira","year":"2011","journal-title":"Auton. Neurosci."},{"key":"10.1016\/j.resp.2023.104115_bib24","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.resp.2017.05.008","article-title":"Brainstem mechanisms underlying the cough reflex and its regulation","volume":"243","author":"Mutolo","year":"2017","journal-title":"Respir. Physiol. Neurobiol."},{"issue":"4","key":"10.1016\/j.resp.2023.104115_bib25","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.brainresbull.2007.07.001","article-title":"The role of excitatory amino acids and substance P in the mediation of the cough reflex within the nucleus tractus solitarii of the rabbit","volume":"74","author":"Mutolo","year":"2007","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.resp.2023.104115_bib26","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1152\/ajpregu.00184.2008","article-title":"Modulation of the cough reflex by antitussive agents within the caudal aspect of the nucleus tractus solitarii in the rabbit","volume":"295","author":"Mutolo","year":"2008","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.resp.2023.104115_bib27","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1152\/ajpregu.00237.2014","article-title":"Inhibitory control of the cough reflex by galanin receptors in the caudal nucleus tractus solitarii of the rabbit","volume":"307","author":"Mutolo","year":"2014","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"1","key":"10.1016\/j.resp.2023.104115_bib28","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1152\/japplphysiol.00790.2015","article-title":"Feed-forward and reciprocal inhibition for gain and phase timing control in a computational model of repetitive cough","volume":"121","author":"Pitts","year":"2016","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.resp.2023.104115_bib29","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.resp.2016.04.008","article-title":"The course of lung inflation alters the central pattern of tracheobronchial cough in cat-the evidence for volume feedback during cough","volume":"229","author":"Poliacek","year":"2016","journal-title":"Respir. Physiol. Neurobiol."},{"key":"10.1016\/j.resp.2023.104115_bib30","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.resp.2017.07.011","article-title":"Role of the dorsomedial medulla in suppression of cough by codeine in cats","volume":"246","author":"Poliacek","year":"2017","journal-title":"Respir. Physiol. Neurobiol."},{"issue":"6","key":"10.1016\/j.resp.2023.104115_bib31","doi-asserted-by":"crossref","first-page":"2179","DOI":"10.1152\/jn.00935.2016","article-title":"Microinjection of kynurenic acid in the rostral nucleus of the tractus solitarius disrupts spatiotemporal aspects of mechanically induced tracheobronchial cough","volume":"117","author":"Poliacek","year":"2017","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.resp.2023.104115_bib32","series-title":"Rang\u00b4s and Dale\u00b4s Pharmacology","first-page":"738","author":"Rang","year":"2016"},{"key":"10.1016\/j.resp.2023.104115_bib33","series-title":"Neural Control of the Respiratory Muscles","article-title":"Neural Control of Coughing and Sneezing","author":"Shannon","year":"1997"},{"key":"10.1016\/j.resp.2023.104115_bib34","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.resp.2016.05.008","article-title":"Changes in vagal afferent drive alter tracheobronchial coughing in anesthetized cats","volume":"203","author":"Simera","year":"2016","journal-title":"Respir. Physiol. Neurobiol."},{"key":"10.1016\/j.resp.2023.104115_bib35","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/0028-3908(89)90088-9","article-title":"Cardiovascular responses elicited by gamma amino butyric acid in the nucleus tractus solitarius: evidence of the action of GABAB receptor","volume":"28","author":"Sved","year":"1989","journal-title":"Neuropharmacology"},{"issue":"1","key":"10.1016\/j.resp.2023.104115_bib36","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1152\/jn.00322.2007","article-title":"GABAergic pump cells of solitary tract nucleus innervate retrotrapezoid nucleus chemoreceptors","volume":"98","author":"Takakura","year":"2007","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.resp.2023.104115_bib37","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1113\/jphysiol.1988.sp017212","article-title":"Lung C-fibre receptor activation and defensive reflexes in anaesthetized cats","volume":"402","author":"Tatar","year":"1988","journal-title":"J. Physiol."},{"issue":"2\u20134","key":"10.1016\/j.resp.2023.104115_bib38","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1159\/000024053","article-title":"Allergen-induced sensory neuroplasticity in airways","volume":"118","author":"Undem","year":"1999","journal-title":"Int. Arch. Allergy Immunol."},{"issue":"3","key":"10.1016\/j.resp.2023.104115_bib39","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1006\/pupt.2002.0362","article-title":"Physiology and plasticity of putative cough fibres in the Guinea pig","volume":"15","author":"Undem","year":"2002","journal-title":"Pulm. Pharm. Ther."},{"key":"10.1016\/j.resp.2023.104115_bib40","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1745-9974-5-12","article-title":"Spatiotemporal regulation of the cough motor pattern","volume":"5","author":"Wang","year":"2009","journal-title":"Cough"},{"issue":"6","key":"10.1016\/j.resp.2023.104115_bib41","doi-asserted-by":"crossref","first-page":"R1423","DOI":"10.1152\/ajpregu.00488.2001","article-title":"GABA-mediated neurotransmission in the ventrolateral NTS plays a role in respiratory regulation in the rat","volume":"283","author":"Wasserman","year":"2002","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.resp.2023.104115_bib42","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/S0165-1838(98)00140-4","article-title":"Receptor subtype specific effects of GABA agonists on neurons receiving aortic depressor nerve inputs within the nucleus of the solitary tract","volume":"73","author":"Zhang","year":"1998","journal-title":"J. Auton. Nerv. Syst."}],"container-title":["Respiratory Physiology & Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569904823001039?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569904823001039?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T22:48:26Z","timestamp":1761605306000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1569904823001039"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":42,"alternative-id":["S1569904823001039"],"URL":"https:\/\/doi.org\/10.1016\/j.resp.2023.104115","relation":{},"ISSN":["1569-9048"],"issn-type":[{"type":"print","value":"1569-9048"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Differential inhibition of cough by GABAA and GABAB receptor antagonists in the nucleus of the solitary tract in cats","name":"articletitle","label":"Article Title"},{"value":"Respiratory Physiology & Neurobiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.resp.2023.104115","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"104115"}}