{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T03:54:04Z","timestamp":1791172444389,"version":"4.1.0"},"reference-count":48,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2012,12,1]],"date-time":"2012-12-01T00:00:00Z","timestamp":1354320000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,12,1]],"date-time":"2012-12-01T00:00:00Z","timestamp":1354320000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revue d'\u00c9pid\u00e9miologie et de Sant\u00e9 Publique"],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1016\/j.respe.2012.04.005","type":"journal-article","created":{"date-parts":[[2012,11,7]],"date-time":"2012-11-07T00:03:49Z","timestamp":1352246629000},"page":"473-480","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["\u00c9pid\u00e9miologie des gastroent\u00e9rites \u00e0 rotavirus chez les enfants \u00e2g\u00e9s de moins de cinq ans en Tunisie \u2013 R\u00e9sultats de la surveillance sentinelle hospitali\u00e8re 2009\u00a0\u00e0 2011"],"prefix":"10.1016","volume":"60","author":[{"given":"M.","family":"Soltani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Bouanene","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Trabelsi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Harbi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Hachicha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Amri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Boussnina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.N.","family":"Gueddiche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.T.","family":"Sfar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Teleb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Ben Ghorbel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Ben Hamida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Suppl. 1","key":"10.1016\/j.respe.2012.04.005_bib0005","doi-asserted-by":"crossref","first-page":"S41","DOI":"10.1093\/clinids\/12.Supplement_1.S41","article-title":"Diarrhea in developed and developing countries: magnitude, special settings, and etiologies","volume":"12","author":"Guerrant","year":"1990","journal-title":"Rev Infect Dis"},{"key":"10.1016\/j.respe.2012.04.005_bib0010","doi-asserted-by":"crossref","first-page":"3865","DOI":"10.1016\/j.vaccine.2006.03.039","article-title":"Enteric infections and the vaccines to counter them: future directions","volume":"24","author":"Levine","year":"2006","journal-title":"Vaccine"},{"issue":"Suppl 3","key":"10.1016\/j.respe.2012.04.005_bib0015","first-page":"S81","article-title":"Discovery of rotavirus: implications for child health","volume":"24","author":"Bishop","year":"2009","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.respe.2012.04.005_bib0020","first-page":"1917","article-title":"Rotaviruses","volume":"2","author":"Estes","year":"2007"},{"key":"10.1016\/j.respe.2012.04.005_bib0025","doi-asserted-by":"crossref","first-page":"565","DOI":"10.3201\/eid0905.020562","article-title":"Global illness and deaths caused by rotavirus disease in children","volume":"9","author":"Parashar","year":"2003","journal-title":"Emerg Infect Dis"},{"issue":"Suppl. 1","key":"10.1016\/j.respe.2012.04.005_bib0030","doi-asserted-by":"crossref","first-page":"S9","DOI":"10.1086\/605025","article-title":"Global mortality associated with rotavirus disease among children in 2004","volume":"200","author":"Parashar","year":"2009","journal-title":"J Infect Dis"},{"key":"10.1016\/j.respe.2012.04.005_bib0035","doi-asserted-by":"crossref","first-page":"304","DOI":"10.3201\/eid1202.050006","article-title":"Rotavirus and severe childhood diarrhea","volume":"12","author":"Parashar","year":"2006","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.respe.2012.04.005_bib0040","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/S0140-6736(06)68815-6","article-title":"Rotavirus vaccines: current prospects and future challenges","volume":"368","author":"Glass","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.respe.2012.04.005_bib0045","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1586\/14760584.6.1.11","article-title":"Rotarix (RIX4414): an oral human rotavirus vaccine","volume":"6","author":"O\u2019Ryan","year":"2007","journal-title":"Expert Rev Vaccines"},{"key":"10.1016\/j.respe.2012.04.005_bib0050","doi-asserted-by":"crossref","first-page":"197","DOI":"10.2165\/00148581-200608030-00008","article-title":"Rotavirus vaccine (RotaTeq)","volume":"8","author":"Keating","year":"2006","journal-title":"Paediatr Drugs"},{"key":"10.1016\/j.respe.2012.04.005_bib0055","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1016\/S0140-6736(08)60524-3","article-title":"Ef\ufb01cacy and safety of an oral live attenuated human rotavirus vaccine against rotavirus gastroenteritis during the \ufb01rst 2\u00a0years of life in Latin American infants: randomised, double-blind controlled phase III study","volume":"371","author":"Linhares","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.respe.2012.04.005_bib0060","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1056\/NEJMoa052664","article-title":"Safety and ef\ufb01cacy of a pentavalent human-bovine (WC3) reassortant rotavirus vaccine","volume":"354","author":"Vesikari","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1016\/j.respe.2012.04.005_bib0065","first-page":"38","article-title":"Meeting of the Global Advisory Committee on Vaccine Safety, December 2010","volume":"86","author":"World Health Organization","year":"2011","journal-title":"Wkly Epidemiol Rec."},{"key":"10.1016\/j.respe.2012.04.005_bib0070","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0399-077X(81)80001-7","article-title":"Gastroent\u00e9rites \u00e0 rotavirus en Tunisie","volume":"11","author":"Boujnah","year":"1981","journal-title":"Med Mal Infect"},{"key":"10.1016\/j.respe.2012.04.005_bib0075","doi-asserted-by":"crossref","first-page":"571","DOI":"10.4269\/ajtmh.2007.77.571","article-title":"Etiology of acute diarrhea in children and adults in Tunis, Tunisia, with emphasis on diarrheagenic Escherichia coli: prevalence, phenotyping, and molecular epidemiology","volume":"77","author":"Al-Gallas","year":"2007","journal-title":"Am J Trop Med Hyg."},{"key":"10.1016\/j.respe.2012.04.005_bib0080","first-page":"599","article-title":"Les gastroent\u00e9rites aigues chez les enfants de moins de 5ans","volume":"87","author":"Tinsa","year":"2009","journal-title":"Tunisie Med"},{"key":"10.1016\/j.respe.2012.04.005_bib0085","doi-asserted-by":"crossref","first-page":"3415","DOI":"10.1128\/JCM.38.9.3415-3419.2000","article-title":"Distribution of rotavirus VP7\u00a0serotypes and VP4\u00a0genotypes circulating in Sousse, Tunisia, from 1995\u00a0to 1999: emergence of natural human reassortants","volume":"38","author":"Trabelsi","year":"2000","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.respe.2012.04.005_bib0090","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1002\/jmv.20919","article-title":"rotavirus strains circulating in the eastern center of Tunisia during a ten-year period (1995\u20132004)","volume":"79","author":"Chouikha","year":"2007","journal-title":"J Med Virol"},{"key":"10.1016\/j.respe.2012.04.005_bib0095","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1002\/jmv.20681","article-title":"Identification of viral agents causing diarrhea among children in the Eastern Center of Tunisia","volume":"78","author":"Fodha","year":"2006","journal-title":"J Med Virol"},{"issue":"Suppl. 1","key":"10.1016\/j.respe.2012.04.005_bib0100","doi-asserted-by":"crossref","first-page":"S239","DOI":"10.1086\/605029","article-title":"Emergence and characterization of human rotavirus G9\u00a0strains in Tunisia","volume":"200","author":"Chouikha","year":"2009","journal-title":"J Infect Dis"},{"key":"10.1016\/j.respe.2012.04.005_bib0105","doi-asserted-by":"crossref","first-page":"e79","DOI":"10.1016\/j.patbio.2009.05.007","article-title":"Evolution of group A Rotavirus strains circulating in Tunisia over a 3-year period (2005\u20132007)","volume":"59","author":"Chouikha","year":"2011","journal-title":"Pathol Biol(Paris)"},{"issue":"Suppl. 2","key":"10.1016\/j.respe.2012.04.005_bib0110","first-page":"S81","article-title":"Evidence-based guidelines for the management of acute gastroenteritis in children in Europe","volume":"46","author":"Guarino","year":"2008","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.respe.2012.04.005_bib0115","unstructured":"World Health Organization. Generic protocol for (i) hospital-based surveillance to estimate the burden of rotavirus among children and (ii) a community-based survey on utilization of health care services for gastroenteritis in children. Geneva, WHO, 2002. Disponible sur: http:\/\/www.who.int\/vaccines-documents\/DocsPDF02\/www698.pdf."},{"key":"10.1016\/j.respe.2012.04.005_bib0120","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1128\/jcm.28.2.276-282.1990","article-title":"Polymerase chain reaction amplification and typing of rotavirus nucleic acid from stool specimens","volume":"28","author":"Gouvea","year":"1990","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.respe.2012.04.005_bib0125","unstructured":"Institut National de la Statistique. Estimation de la population au premier juillet 2010. Disponible sur: www.ins.nat.tn (Consult\u00e9 le 26\/08\/2011)."},{"issue":"Suppl. 1","key":"10.1016\/j.respe.2012.04.005_bib0130","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1086\/431515","article-title":"Rotavirus in Asia: the value of surveillance for informing decisions about the introduction of new vaccines","volume":"192","author":"Bresee","year":"2005","journal-title":"J Infect Dis"},{"key":"10.1016\/j.respe.2012.04.005_bib0135","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/1471-2334-11-9","article-title":"Burden of rotavirus gastroenteritis in the Middle Eastern and North African pediatric population","volume":"11","author":"Khoury","year":"2011","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.respe.2012.04.005_bib0140","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1128\/JCM.01381-08","article-title":"Predominance and circulation of enteric viruses in the region of Greater Cairo, Egypt","volume":"47","author":"Kamel","year":"2009","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.respe.2012.04.005_bib0145","first-page":"1759","article-title":"Etiology of childhood diarrhea in Zliten, Libya","volume":"26","author":"Ali","year":"2005","journal-title":"Saudi Med J"},{"key":"10.1016\/j.respe.2012.04.005_bib0150","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1111\/j.1365-3156.2011.02756.x","article-title":"Rotavirus and norovirus infections in children in Sana\u2019a","volume":"16","author":"Kirby","year":"2011","journal-title":"Yemen. Trop Med Int Health"},{"key":"10.1016\/j.respe.2012.04.005_bib0155","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1128\/JCM.02244-07","article-title":"Molecular epidemiology of rotavirus diarrhea among children in Saudi Arabia: first detection of G9\u00a0and G12\u00a0strains","volume":"46","author":"Kheyami","year":"2008","journal-title":"J Clin Microbiol"},{"issue":"Suppl 1","key":"10.1016\/j.respe.2012.04.005_bib0160","doi-asserted-by":"crossref","first-page":"S70","DOI":"10.1086\/605048","article-title":"Epidemiology of rotavirus gastroenteritis among children<5\u00a0years of age in Morocco during 1\u00a0year of sentinel hospital surveillance, June 2006\u2013May 2007","volume":"200","author":"Benhafid","year":"2009","journal-title":"J Infect Dis"},{"key":"10.1016\/j.respe.2012.04.005_bib0165","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1017\/S0950268807007868","article-title":"Genotypic characterization of rotaviruses and prevalence of serotype-speci\ufb01c serum antibodies in children in Kuwait","volume":"135","author":"Marmash","year":"2007","journal-title":"Epidemiol Infect"},{"issue":"Suppl. 1","key":"10.1016\/j.respe.2012.04.005_bib0170","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.1086\/516714","article-title":"Multicenter prospective study of the burden of rotavirus acute gastroenteritis in Europe, 2004\u20132005: the REVEAL study","volume":"195","author":"Van Damme","year":"2007","journal-title":"J Infect Dis"},{"key":"10.1016\/j.respe.2012.04.005_bib0175","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1542\/peds.2007-3378","article-title":"Active, population-based surveillance for severe rotavirus gastroenteritis in children in the United States","volume":"122","author":"Payne","year":"2008","journal-title":"Pediatrics"},{"key":"10.1016\/j.respe.2012.04.005_bib0180","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1016\/j.vaccine.2003.10.029","article-title":"Hospitalisations for gastroenteritis: the role of rotavirus","volume":"22","author":"Rivest","year":"2004","journal-title":"Vaccine"},{"key":"10.1016\/j.respe.2012.04.005_bib0185","doi-asserted-by":"crossref","first-page":"166","DOI":"10.7883\/yoken.JJID.2004.166","article-title":"Estimation of annual incidence, age-specific incidence rate, and cumulative risk of rotavirus gastroenteritis among children in Japan","volume":"57","author":"Yokoo","year":"2004","journal-title":"Jpn J Infect Dis"},{"issue":"Suppl 1","key":"10.1016\/j.respe.2012.04.005_bib0190","doi-asserted-by":"crossref","first-page":"S42","DOI":"10.1097\/INF.0b013e3181fefd78","article-title":"United States rotavirus strain surveillance from 2005\u00a0to 2008: genotype prevalence before and after vaccine introduction","volume":"30","author":"Hull","year":"2011","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.respe.2012.04.005_bib0195","doi-asserted-by":"crossref","first-page":"252","DOI":"10.5694\/j.1326-5377.1998.tb140248.x","article-title":"Rotavirus infection and rates of hospitalization for acute gastroenteritis in young children in Australia, 1993\u20131996","volume":"169","author":"Carlin","year":"1998","journal-title":"Med J Aust"},{"key":"10.1016\/j.respe.2012.04.005_bib0200","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1007\/s00508-006-0599-9","article-title":"Active hospital-based surveillance of rotavirus diarrhea in Austrian children, period 1997\u00a0to 2003","volume":"118","author":"Rendi-Wagner","year":"2006","journal-title":"Wien Klin Wochenschr"},{"key":"10.1016\/j.respe.2012.04.005_bib0205","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1017\/S0950268806006091","article-title":"The paediatric burden of rotavirus disease in Europe","volume":"134","author":"The Pediatric Rotavirus European Committee (PROTECT)","year":"2006","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.respe.2012.04.005_bib0210","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/S1473-3099(09)70179-3","article-title":"Burden of disease and circulating serotypes of rotavirus infection in sub-Saharan Africa: systematic review and meta-analysis","volume":"9","author":"Sanchez-Padilla","year":"2009","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.respe.2012.04.005_bib0215","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1086\/340103","article-title":"The role of serum antibodies in the protection against rotavirus disease: an overview","volume":"34","author":"Jiang","year":"2002","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.respe.2012.04.005_bib0220","first-page":"171","article-title":"Global seasonality of rotavirus infections","volume":"68","author":"Cook","year":"1990","journal-title":"Bull World Health Organ"},{"key":"10.1016\/j.respe.2012.04.005_bib0225","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1097\/00006454-200203000-00012","article-title":"Clinical presentations of rotavirus infection among hospitalized children","volume":"21","author":"Staat","year":"2002","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.respe.2012.04.005_bib0230","doi-asserted-by":"crossref","first-page":"e393","DOI":"10.1542\/peds.2008-2088","article-title":"Hospital-based surveillance to estimate the burden of rotavirus gastroenteritis among European children younger than 5\u00a0years of age","volume":"123","author":"Forster","year":"2009","journal-title":"Pediatrics"},{"key":"10.1016\/j.respe.2012.04.005_bib0235","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1002\/rmv.448","article-title":"Global distribution of rotavirus serotypes\/genotypes and its implication for the development and implementation of an effective rotavirus vaccine","volume":"15","author":"Santos","year":"2005","journal-title":"Rev Med Virol"},{"issue":"Suppl. 1","key":"10.1016\/j.respe.2012.04.005_bib0240","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1097\/INF.0b013e3181fefa1f","article-title":"Real-world impact of rotavirus vaccination","volume":"30","author":"Patel","year":"2011","journal-title":"Pediatr Infect Dis J"}],"container-title":["Revue d'\u00c9pid\u00e9miologie et de Sant\u00e9 Publique"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0398762012005810?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0398762012005810?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T00:35:17Z","timestamp":1759970117000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0398762012005810"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12]]},"references-count":48,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["S0398762012005810"],"URL":"https:\/\/doi.org\/10.1016\/j.respe.2012.04.005","relation":{},"ISSN":["0398-7620"],"issn-type":[{"value":"0398-7620","type":"print"}],"subject":[],"published":{"date-parts":[[2012,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"\u00c9pid\u00e9miologie des gastroent\u00e9rites \u00e0 rotavirus chez les enfants \u00e2g\u00e9s de moins de cinq ans en Tunisie \u2013 R\u00e9sultats de la surveillance sentinelle hospitali\u00e8re 2009\u00a0\u00e0 2011","name":"articletitle","label":"Article Title"},{"value":"Revue d'\u00c9pid\u00e9miologie et de Sant\u00e9 Publique","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.respe.2012.04.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}