{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T02:27:44Z","timestamp":1769308064071,"version":"3.49.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Resuscitation"],"published-print":{"date-parts":[[2008,1]]},"DOI":"10.1016\/j.resuscitation.2007.07.002","type":"journal-article","created":{"date-parts":[[2007,8,21]],"date-time":"2007-08-21T12:56:51Z","timestamp":1187701011000},"page":"83-88","source":"Crossref","is-referenced-by-count":42,"title":["Intranasal selective brain cooling in pigs"],"prefix":"10.1016","volume":"76","author":[{"given":"L.","family":"Covaciu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Allers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Enblad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Lunderquist","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Wieloch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Rubertsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.resuscitation.2007.07.002_bib1","doi-asserted-by":"crossref","unstructured":"Hypothermia After Cardiac Arrest Group: Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. N Engl J Med 2002;346(8):549\u201356.","DOI":"10.1056\/NEJMoa012689"},{"issue":"8","key":"10.1016\/j.resuscitation.2007.07.002_bib2","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1056\/NEJMoa003289","article-title":"Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia","volume":"346","author":"Bernard","year":"2002","journal-title":"N Engl J Med"},{"issue":"6","key":"10.1016\/j.resuscitation.2007.07.002_bib3","first-page":"1449","article-title":"On behalf of the Collaborative Group on induced hypothermia for neuroprotection after cardiac arrest: hypothermia for neuroprotection after cardiac arrest: systematic review and individual patient data meta-analysis","volume":"33","author":"Holzer","year":"2005","journal-title":"Crit Care Med"},{"issue":"1","key":"10.1016\/j.resuscitation.2007.07.002_bib4","doi-asserted-by":"crossref","first-page":"91","DOI":"10.3171\/jns.2000.92.1.0091","article-title":"Comparative neuroprotective efficacy of prolonged moderate intraischemic and postischemic hypothermia in focal cerebral ischemia","volume":"92","author":"Huh","year":"2000","journal-title":"J Neurosurg"},{"issue":"8","key":"10.1016\/j.resuscitation.2007.07.002_bib5","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1161\/01.STR.32.8.1847","article-title":"Cooling for acute ischemic brain damage (cool aid)\u2014an open pilot study of induced hypothermia in acute ischemic stroke","volume":"32","author":"Krieger","year":"2001","journal-title":"Stroke"},{"issue":"1","key":"10.1016\/j.resuscitation.2007.07.002_bib6","doi-asserted-by":"crossref","first-page":"S39","DOI":"10.1016\/j.resuscitation.2005.10.009","article-title":"European Resuscitation Council: guidelines for resuscitation 2005 Section 4. Adult advanced life support","volume":"67","author":"Nolan","year":"2005","journal-title":"Resuscitation"},{"issue":"2","key":"10.1016\/j.resuscitation.2007.07.002_bib7","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1161\/01.STR.29.2.529","article-title":"Combating hyperthermia in acute stroke: a significant clinical concern","volume":"29","author":"Ginsberg","year":"1998","journal-title":"Stroke"},{"key":"10.1016\/j.resuscitation.2007.07.002_bib8","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.resuscitation.2005.04.002","article-title":"Induction of mild hypothermia with infusion of cold (4\u00b0C) fluid during ongoing experimental CPR","volume":"66","author":"Nordmark","year":"2005","journal-title":"Resuscitation"},{"issue":"3","key":"10.1016\/j.resuscitation.2007.07.002_bib9","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1212\/WNL.56.3.292","article-title":"Clinical trial of an air-circulating cooling blanket for fever control in critically ill neurologic patients","volume":"56","author":"Mayer","year":"2000","journal-title":"Neurology"},{"issue":"11","key":"10.1016\/j.resuscitation.2007.07.002_bib10","doi-asserted-by":"crossref","first-page":"2481","DOI":"10.1097\/00003246-200211000-00013","article-title":"Safety and efficacy of a novel intravascular cooling device to control body temperature in neurologic intensive care patients: a prospective pilot study","volume":"30","author":"Schmutzhard","year":"2002","journal-title":"Crit Care Med"},{"issue":"3","key":"10.1016\/j.resuscitation.2007.07.002_bib11","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1097\/00000542-200009000-00010","article-title":"Core cooling by central venous infusion of icecold (4\u00b0C and 20\u00b0C) fluid: isolation of core and peripheral thermal compartments","volume":"93","author":"Rajek","year":"2000","journal-title":"Anesthesiology"},{"issue":"10","key":"10.1016\/j.resuscitation.2007.07.002_bib12","doi-asserted-by":"crossref","first-page":"2164","DOI":"10.1097\/01.CCM.0000142700.19377.AE","article-title":"Mild hypothermia during prolonged cardiopulmonary cerebral resuscitation increases conscious survival in dogs","volume":"32","author":"Nozari","year":"2004","journal-title":"Crit Care Med"},{"issue":"9","key":"10.1016\/j.resuscitation.2007.07.002_bib13","doi-asserted-by":"crossref","first-page":"S369","DOI":"10.1097\/01.CCM.0000139461.46564.51","article-title":"A new method for inducing hypothermia during cardiac arrest","volume":"32","author":"Zviman","year":"2004","journal-title":"Crit Care Med"},{"issue":"12","key":"10.1016\/j.resuscitation.2007.07.002_bib14","doi-asserted-by":"crossref","first-page":"2558","DOI":"10.1097\/01.CCM.0000148087.41418.0A","article-title":"Keeping a cool head: How to induce and maintain hypothermia?","volume":"32","author":"Polderman","year":"2004","journal-title":"Crit Care Med"},{"issue":"9","key":"10.1016\/j.resuscitation.2007.07.002_bib15","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1007\/s00134-004-2350-1","article-title":"A novel approach for selective brain cooling: implications for hypercapnia and seizure activity","volume":"30","author":"Trubel","year":"2004","journal-title":"Intensive Care Med"},{"issue":"2","key":"10.1016\/j.resuscitation.2007.07.002_bib16","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1007\/s00270-004-0271-6","article-title":"A new method of selective, rapid cooling of the brain: an experimental study","volume":"29","author":"Allers","year":"2006","journal-title":"Cardiovasc Intervent Radiol"},{"issue":"10","key":"10.1016\/j.resuscitation.2007.07.002_bib17","doi-asserted-by":"crossref","first-page":"2502","DOI":"10.1097\/01.CCM.0000084845.76762.F4","article-title":"Nasopharyngeal cooling selectively and rapidly decreases brain temperature and attenuates neuronal damage, even if initiated at the onset of cardiopulmonary resuscitation in rats","volume":"31","author":"Hagioka","year":"2003","journal-title":"Crit Care Med"},{"issue":"9","key":"10.1016\/j.resuscitation.2007.07.002_bib18","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0166-2236(99)01401-0","article-title":"Pathobiology of ischemic stroke: an integrated view","volume":"22","author":"Dirnagl","year":"1999","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.resuscitation.2007.07.002_bib19","doi-asserted-by":"crossref","first-page":"291","DOI":"10.2170\/jjphysiol.51.291","article-title":"Selective brain cooling in mammals and birds","volume":"51","author":"Jensen","year":"2001","journal-title":"Jpn J Physiol"},{"key":"10.1016\/j.resuscitation.2007.07.002_bib20","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0929-693X(99)80080-3","article-title":"Le refroidissement s\u00e9lectif du cerveau","volume":"6","author":"Corrard","year":"1999","journal-title":"Arch Pediatr"},{"issue":"3 Pt2","key":"10.1016\/j.resuscitation.2007.07.002_bib21","first-page":"1108","article-title":"Selective brain cooling: role of angularis oculi vein and nasal thermoreception","volume":"273","author":"Maloney","year":"1997","journal-title":"Am J Physiol"},{"issue":"5","key":"10.1016\/j.resuscitation.2007.07.002_bib22","first-page":"326","article-title":"Complex intracranial arterial anatomy in swine is unsuitable for cerebral infarction projects","volume":"55","author":"Burbridge","year":"2004","journal-title":"Can Assoc Radiol J"},{"issue":"1","key":"10.1016\/j.resuscitation.2007.07.002_bib23","doi-asserted-by":"crossref","first-page":"R108","DOI":"10.1152\/ajpregu.2001.281.1.R108","article-title":"Rectal temperature measurement results in artifactual evidence of selective brain cooling","volume":"281","author":"Maloney","year":"2001","journal-title":"Am J Pysiol Regul Integr Comp Physiol"},{"issue":"1","key":"10.1016\/j.resuscitation.2007.07.002_bib24","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1097\/00000542-200107000-00013","article-title":"Moderate hypothermia depresses arterial baroreflex control of heart rate during, and delays its recovery after, general anesthesia in human","volume":"95","author":"Tanaka","year":"2001","journal-title":"Anesthesiology"},{"issue":"557(Pt 1)","key":"10.1016\/j.resuscitation.2007.07.002_bib25","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1113\/jphysiol.2003.059444","article-title":"Effect of hypothermia on baroreflex control of heart rate and renal sympathetic nerve activity in anaesthetized rats","volume":"15","author":"Sabharwal","year":"2004","journal-title":"J Physiol"},{"issue":"2","key":"10.1016\/j.resuscitation.2007.07.002_bib26","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1007\/s003950170071","article-title":"Influence of mild hypothermia on myocardial contractility and circulatory function","volume":"96","author":"Weisser","year":"2001","journal-title":"Basic Res Cardiol"},{"key":"10.1016\/j.resuscitation.2007.07.002_bib27","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1056\/NEJM199706123362407","article-title":"Mild perioperative hypothermia","volume":"336","author":"Sessler","year":"1997","journal-title":"N Engl J Med"},{"issue":"4","key":"10.1016\/j.resuscitation.2007.07.002_bib28","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.physbeh.2005.02.002","article-title":"Brain and body temperature homeostasis during sodium pentobarbital anesthesia with and without body warming in rats","volume":"84","author":"Kiyatkin","year":"2005","journal-title":"Physiol Behav"},{"issue":"5","key":"10.1016\/j.resuscitation.2007.07.002_bib29","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1097\/00000542-199505000-00015","article-title":"The relation between cerebral metabolic rate and ischemic depolarization: a comparison of the effects of hypothermia, pentobarbital, and isoflurane","volume":"82","author":"Nakashima","year":"1995","journal-title":"Anesthesiology"},{"key":"10.1016\/j.resuscitation.2007.07.002_bib30","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1097\/01.aco.0000191890.36691.cc","article-title":"Thermal management of the patient: Where does the patient lose and\/or gain temperature?","volume":"18","author":"Taguchi","year":"2005","journal-title":"Curr Opin Anesthesiol"},{"issue":"5","key":"10.1016\/j.resuscitation.2007.07.002_bib31","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1152\/jappl.1999.87.5.1609","article-title":"Direct cooling of the human brain by heat loss from the upper respiratory tract","volume":"87","author":"Mariak","year":"1999","journal-title":"J Appl Physiol"},{"issue":"6","key":"10.1016\/j.resuscitation.2007.07.002_bib32","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1016\/j.mehy.2004.05.003","article-title":"Selective brain cooling seems to be a mechanism leading to human craniofacial diversity observed in different geographical regions","volume":"63","author":"Irmak","year":"2004","journal-title":"Med Hypotheses"},{"issue":"1(1)","key":"10.1016\/j.resuscitation.2007.07.002_bib33","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/1743-8454-1-2","article-title":"Evidence of connections between cerebrospinal fluid and nasal lymphatic vessels in humans, non-human primates and other mammalian species","volume":"10","author":"Johnston","year":"2004","journal-title":"Cerebrospinal Fluid Res"},{"issue":"suppl. 96","key":"10.1016\/j.resuscitation.2007.07.002_bib34","first-page":"S406","article-title":"Positive selective brain cooling method: a novel, simple and selective nasopharyngeal brain cooling method","author":"Dohi","year":"2006","journal-title":"Acta Neurochir"},{"issue":"4","key":"10.1016\/j.resuscitation.2007.07.002_bib35","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1111\/j.1365-2044.1992.tb02177.x","article-title":"Nosocomial sinusitis in ventilated patients. Nasotracheal versus orotracheal intubation","volume":"47","author":"Bach","year":"1992","journal-title":"Anaesthesia"},{"issue":"3","key":"10.1016\/j.resuscitation.2007.07.002_bib36","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1086\/514711","article-title":"Nosocomial sinusitis in patients in the medical intensiva care unit, a prospective epidemiological study","volume":"27","author":"George","year":"1998","journal-title":"Clin Infect Dis"},{"issue":"5","key":"10.1016\/j.resuscitation.2007.07.002_bib37","first-page":"R583","article-title":"Hospital-aquired sinusitis is a common cause of fever of unknown origin in orotracheally intubated critically ill patients","volume":"9","author":"van Zanten","year":"2006","journal-title":"Crit Care Med"}],"container-title":["Resuscitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300957207003711?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300957207003711?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,2]],"date-time":"2019-05-02T09:52:29Z","timestamp":1556790749000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300957207003711"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,1]]}},"alternative-id":["S0300957207003711"],"URL":"https:\/\/doi.org\/10.1016\/j.resuscitation.2007.07.002","relation":{},"ISSN":["0300-9572"],"issn-type":[{"value":"0300-9572","type":"print"}],"subject":[],"published":{"date-parts":[[2008,1]]}}}