{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T07:16:47Z","timestamp":1792653407072,"version":"4.5.0"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004590","name":"South-Eastern Norway Regional Health Authority","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004590","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","resuscitationjournal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Resuscitation"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1016\/j.resuscitation.2016.06.014","type":"journal-article","created":{"date-parts":[[2016,6,24]],"date-time":"2016-06-24T12:16:39Z","timestamp":1466770599000},"page":"7-13","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":51,"special_numbering":"C","title":["Myocardial perfusion and oxidative stress after 21% vs. 100% oxygen ventilation and uninterrupted chest compressions in severely asphyxiated piglets"],"prefix":"10.1016","volume":"106","author":[{"given":"Anne Lee","family":"Solev\u00e5g","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg M.","family":"Schm\u00f6lzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"O\u2019Reilly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tze-Fun","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa K.","family":"Hornberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Britt","family":"Nakstad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Po-Yin","family":"Cheung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.resuscitation.2016.06.014_bib0130","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1542\/peds.107.4.642","article-title":"Resuscitation with room air instead of 100% oxygen prevents oxidative stress in moderately asphyxiated term neonates","volume":"107","author":"Vento","year":"2001","journal-title":"Pediatrics"},{"key":"10.1016\/j.resuscitation.2016.06.014_bib0135","doi-asserted-by":"crossref","first-page":"1970","DOI":"10.1016\/S0140-6736(10)60543-0","article-title":"Resuscitation of newborn infants: from oxygen to room air","volume":"376","author":"Saugstad","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.resuscitation.2016.06.014_bib0140","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1159\/000143397","article-title":"Resuscitation of newborn infants with 21% or 100% oxygen: an updated systematic review and meta-analysis","volume":"94","author":"Saugstad","year":"2008","journal-title":"Neonatology"},{"key":"10.1016\/j.resuscitation.2016.06.014_bib0145","doi-asserted-by":"crossref","first-page":"S204","DOI":"10.1161\/CIR.0000000000000276","article-title":"Part 7: Neonatal resuscitation: 2015 international consensus on cardiopulmonary resuscitation and emergency cardiovascular care science with treatment recommendations","volume":"132","author":"Perlman","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.resuscitation.2016.06.014_bib0150","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1203\/PDR.0b013e3181b3b110","article-title":"Circulatory recovery is as fast with air ventilation as with 100% oxygen after asphyxia-induced cardiac arrest in piglets","volume":"66","author":"Linner","year":"2009","journal-title":"Pediatr Res"},{"key":"10.1016\/j.resuscitation.2016.06.014_bib0155","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1159\/000275560","article-title":"Resuscitation of severely asphyctic newborn pigs with cardiac arrest by using 21% or 100% oxygen","volume":"98","author":"Solevag","year":"2010","journal-title":"Neonatology"},{"key":"10.1016\/j.resuscitation.2016.06.014_bib0160","doi-asserted-by":"crossref","first-page":"S40","DOI":"10.1161\/CIR.0000000000000271","article-title":"Part 2: Evidence evaluation and management of conflicts of interest: 2015 international consensus on cardiopulmonary resuscitation and emergency cardiovascular care science with treatment recommendations","volume":"132","author":"Morley","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.resuscitation.2016.06.014_bib0165","doi-asserted-by":"crossref","first-page":"e9","DOI":"10.1016\/j.resuscitation.2016.01.008","article-title":"Reply to: \u2018What initial oxygen is best for preterm infants in the delivery room? A response to the 2015 neonatal resuscitation guidelines.\u2019","volume":"101","author":"Wyllie","year":"2016","journal-title":"Resuscitation"},{"key":"10.1016\/j.resuscitation.2016.06.014_bib0170","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1161\/hc0502.102963","article-title":"Importance of continuous chest compressions during cardiopulmonary resuscitation: improved outcome during a simulated single lay-rescuer scenario","volume":"105","author":"Kern","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.resuscitation.2016.06.014_bib0175","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.resuscitation.2013.10.011","article-title":"3:1 compression to ventilation ratio versus continuous chest compression with asynchronous ventilation in a porcine model of neonatal resuscitation","volume":"85","author":"Schmolzer","year":"2014","journal-title":"Resuscitation"},{"key":"10.1016\/j.resuscitation.2016.06.014_bib0180","doi-asserted-by":"crossref","first-page":"e1000412","DOI":"10.1371\/journal.pbio.1000412","article-title":"Improving bioscience research reporting: the arrive guidelines for reporting animal research","volume":"8","author":"Kilkenny","year":"2010","journal-title":"PLoS Biol"},{"key":"10.1016\/j.resuscitation.2016.06.014_bib0185","series-title":"Methods in enzymology","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/0076-6879(82)85055-6","author":"B\u00e1r\u00e1ny","year":"1982"},{"key":"10.1016\/j.resuscitation.2016.06.014_bib0190","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.ejphar.2006.06.044","article-title":"Inhibition of sulfur compounds and antioxidants on mmp-2 and -9 at the activity level found during neonatal hypoxia-reoxygenation","volume":"544","author":"Emara","year":"2006","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.resuscitation.2016.06.014_bib0195","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.ejphar.2013.09.017","article-title":"Effects of post-resuscitation administration with sodium hydrosulfide on cardiac recovery in hypoxia-reoxygenated newborn piglets","volume":"718","author":"Cheung","year":"2013","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.resuscitation.2016.06.014_bib0200","doi-asserted-by":"crossref","first-page":"F229","DOI":"10.1136\/adc.2004.056986","article-title":"Restoration of cardiopulmonary function with 21% versus 100% oxygen after hypoxaemia in newborn pigs","volume":"90","author":"Fugelseth","year":"2005","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"10.1016\/j.resuscitation.2016.06.014_bib0205","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1111\/j.1365-2362.2004.01378.x","article-title":"Increased myocardial matrix metalloproteinases in hypoxic newborn pigs during resuscitation: effects of oxygen and carbon dioxide","volume":"34","author":"Borke","year":"2004","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.resuscitation.2016.06.014_bib0210","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1016\/j.resuscitation.2010.06.007","article-title":"Extended series of cardiac compressions during CPR in a swine model of perinatal asphyxia","volume":"81","author":"Solevag","year":"2010","journal-title":"Resuscitation"},{"key":"10.1016\/j.resuscitation.2016.06.014_bib0215","doi-asserted-by":"crossref","first-page":"F417","DOI":"10.1136\/adc.2010.200386","article-title":"Return of spontaneous circulation with a compression:ventilation ratio of 15:2 versus 3:1 in newborn pigs with cardiac arrest due to asphyxia","volume":"96","author":"Solevag","year":"2011","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"10.1016\/j.resuscitation.2016.06.014_bib0220","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1203\/00006450-198912000-00006","article-title":"Blood flow during cardiopulmonary resuscitation with simultaneous compression and ventilation in infant pigs","volume":"26","author":"Berkowitz","year":"1989","journal-title":"Pediatr Res"},{"key":"10.1016\/j.resuscitation.2016.06.014_bib0225","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.resuscitation.2015.08.001","article-title":"Chest compressions in newborn animal models: a review","volume":"96","author":"Solevag","year":"2015","journal-title":"Resuscitation"},{"key":"10.1016\/j.resuscitation.2016.06.014_bib0230","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1161\/hc4501.098926","article-title":"Adverse hemodynamic effects of interrupting chest compressions for rescue breathing during cardiopulmonary resuscitation for ventricular fibrillation cardiac arrest","volume":"104","author":"Berg","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.resuscitation.2016.06.014_bib0235","doi-asserted-by":"crossref","first-page":"1743","DOI":"10.1161\/01.CIR.101.14.1743","article-title":"Bystander chest compressions and assisted ventilation independently improve outcome from piglet asphyxial pulseless cardiac arrest","volume":"101","author":"Berg","year":"2000","journal-title":"Circulation"},{"key":"10.1016\/j.resuscitation.2016.06.014_bib0240","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1001\/jama.2010.1392","article-title":"Chest compression-only CPR by lay rescuers and survival from out-of-hospital cardiac arrest","volume":"304","author":"Bobrow","year":"2010","journal-title":"JAMA"},{"key":"10.1016\/j.resuscitation.2016.06.014_bib0245","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1186\/1757-7241-20-73","article-title":"Minute ventilation at different compression to ventilation ratios, different ventilation rates, and continuous chest compressions with asynchronous ventilation in a newborn manikin","volume":"20","author":"Solevag","year":"2012","journal-title":"Scand J Trauma Resusc Emerg Med"},{"key":"10.1016\/j.resuscitation.2016.06.014_bib0250","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1111\/j.1651-2227.2000.tb18421.x","article-title":"Predicting the outcome of term neonates with intrapartum asphyxia","volume":"89","author":"Cheung","year":"2000","journal-title":"Acta Paediatr"}],"container-title":["Resuscitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300957216301113?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300957216301113?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,9]],"date-time":"2019-08-09T21:40:49Z","timestamp":1565386849000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300957216301113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9]]},"references-count":25,"alternative-id":["S0300957216301113"],"URL":"https:\/\/doi.org\/10.1016\/j.resuscitation.2016.06.014","relation":{},"ISSN":["0300-9572"],"issn-type":[{"value":"0300-9572","type":"print"}],"subject":[],"published":{"date-parts":[[2016,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Myocardial perfusion and oxidative stress after 21% vs. 100% oxygen ventilation and uninterrupted chest compressions in severely asphyxiated piglets","name":"articletitle","label":"Article Title"},{"value":"Resuscitation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.resuscitation.2016.06.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}