{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T00:32:39Z","timestamp":1788568359499,"version":"build-2803163510"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,8,9]],"date-time":"2020-08-09T00:00:00Z","timestamp":1596931200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001711","name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","resuscitationjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Resuscitation"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1016\/j.resuscitation.2020.07.030","type":"journal-article","created":{"date-parts":[[2020,8,11]],"date-time":"2020-08-11T11:49:42Z","timestamp":1597146582000},"page":"143-151","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Brain networks involved in generalized periodic discharges (GPD) in post-anoxic-ischemic encephalopathy"],"prefix":"10.1016","volume":"155","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7979-0994","authenticated-orcid":false,"given":"Pia","family":"De Stefano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0426-8242","authenticated-orcid":false,"given":"Margherita","family":"Carboni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah","family":"Pugin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6702-0167","authenticated-orcid":false,"given":"Margitta","family":"Seeck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1877-8625","authenticated-orcid":false,"given":"Serge","family":"Vulli\u00e9moz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.resuscitation.2020.07.030_bib0005","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1161\/CIR.0000000000000659","article-title":"Heart disease and stroke statistics-2019 update: a report from the American Heart Association","volume":"139","author":"Benjamin","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0010","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1002\/ana.21984","article-title":"Prognostication after cardiac arrest and hypothermia: a prospective study","volume":"67","author":"Rossetti","year":"2010","journal-title":"Ann Neurol"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0015","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1212\/WNL.0000000000002462","article-title":"Standardized EEG interpretation accurately predicts prognosis after cardiac arrest","volume":"86","author":"Westhall","year":"2016","journal-title":"Neurology"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0020","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.resuscitation.2015.03.005","article-title":"Malignant EEG patterns in cardiac arrest patients treated with targeted temperature management who survive to hospital discharge","volume":"90","author":"Amorim","year":"2015","journal-title":"Resuscitation"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0025","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/WNP.0b013e3182784729","article-title":"American clinical neurophysiology society\u2019s standardized critical care EEG terminology: 2012 version","volume":"30","author":"Hirsch","year":"2013","journal-title":"J Clin Neurophysiol"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0030","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1111\/epi.12270","article-title":"Unified EEG terminology and criteria for nonconvulsive status epilepticus","volume":"54","author":"Beniczky","year":"2013","journal-title":"Epilepsia"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0035","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1212\/WNL.0b013e3182735cd7","article-title":"Generalized periodic discharges in the critically ill: a case-control study of 200 patients","volume":"79","author":"Foreman","year":"2012","journal-title":"Neurology"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0040","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/S1474-4422(16)00015-6","article-title":"Neurological prognostication of outcome in patients in coma after cardiac arrest","volume":"15","author":"Rossetti","year":"2016","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0045","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.resuscitation.2018.12.007","article-title":"Postmortem histopathology of electroencephalography and evoked potentials in postanoxic coma","volume":"134","author":"van Putten","year":"2019","journal-title":"Resuscitation"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0050","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1111\/epi.13202","article-title":"Generalized epileptiform discharges in postanoxic encephalopathy: quantitative characterization in relation to outcome","volume":"56","author":"Ruijter","year":"2015","journal-title":"Epilepsia"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0055","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.yebeh.2015.04.007","article-title":"Generalized periodic discharges: pathophysiology and clinical considerations","volume":"49","author":"van Putten","year":"2015","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0060","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.clinph.2013.08.005","article-title":"Generalized periodic discharges after acute cerebral ischemia: Reflection of selective synaptic failure?","volume":"125","author":"Tjepkema-Cloostermans","year":"2014","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0065","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1016\/j.clinph.2019.09.006","article-title":"The network integration of epileptic activity in relation to surgical outcome","volume":"130","author":"Carboni","year":"2019","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0070","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0123807","article-title":"Neuronal networks during burst suppression as revealed by source analysis","volume":"10","author":"Japaridze","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0075","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.pscychresns.2010.04.012","article-title":"3-D cytoarchitectonic parcellation of human orbitofrontal cortex. Correlation with postmortem MRI","volume":"183","author":"Uylings","year":"2010","journal-title":"Psychiatry Res: Neuroimaging"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0080","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1177\/088506668800300304","article-title":"Coma following cardiac arrest: a review of the clinical features, management, and prognosis","volume":"3","author":"Maiese","year":"1988","journal-title":"J Intensive Care Med"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0085","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1001\/archinte.1962.03620190020003","article-title":"Delayed neurological deterioration after anoxia","volume":"110","author":"Plum","year":"1962","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0090","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1161\/CIR.0000000000000702","article-title":"Standards for studies of neurological prognostication in comatose survivors of cardiac arrest: a scientific statement from the American Heart Association","volume":"140","author":"Geocadin","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0095","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1093\/qjmed\/hcs016","article-title":"Hypoxic-ischaemic brain injury: imaging and neurophysiology abnormalities related to outcome","volume":"105","author":"Howard","year":"2012","journal-title":"Qjm"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0100","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1097\/WNP.0000000000000466","article-title":"Neuroimaging correlates of periodic discharges","volume":"35","author":"Herlopian","year":"2018","journal-title":"J Clin Neurophysiol"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0105","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1038\/s41593-018-0164-7","article-title":"Thalamic dual control of sleep and wakefulness","volume":"21","author":"Gent","year":"2018","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0110","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1126\/science.1169626","article-title":"The human K-complex represents an isolated cortical down-state","volume":"324","author":"Cash","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0115","doi-asserted-by":"crossref","first-page":"15236","DOI":"10.1073\/pnas.0504935102","article-title":"Generalized epileptic discharges show thalamocortical activation and suspension of the default state of the brain","volume":"102","author":"Gotman","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0120","doi-asserted-by":"crossref","DOI":"10.1097\/01.CCM.0000295667.66853.BC","article-title":"Nonconvulsive electrographic seizures after traumatic brain injury result in a delayed, prolonged increase in intracranial pressure and metabolic crisis","volume":"35","author":"Vespa","year":"2007","journal-title":"Crit Care Med"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0125","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.eplepsyres.2015.12.004","article-title":"Status epilepticus: clinical characteristics and EEG patterns associated with and without MRI diffusion restriction in 69 patients","volume":"120","author":"Rennebaum","year":"2016","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0130","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.nicl.2015.07.014","article-title":"Thalamocortical relationship in epileptic patients with generalized spike and wave discharges\u2014a multimodal neuroimaging study","volume":"9","author":"Zhang","year":"2015","journal-title":"NeuroImage Clin"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0135","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.cnp.2019.07.001","article-title":"Nonconvulsive seizures and nonconvulsive status epilepticus in the neuro ICU should or should not be treated aggressively: a debate","volume":"4","author":"Rossetti","year":"2019","journal-title":"Clin Neurophysiol Pract"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0140","doi-asserted-by":"crossref","DOI":"10.1001\/archneurol.2009.100","article-title":"How seizure detection by continuous electroencephalographic monitoring affects the prescribing of antiepileptic medications","volume":"66","author":"Kilbride","year":"2009","journal-title":"Arch Neurol"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0145","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1745-6215-15-433","article-title":"Treatment of electroencephalographic status epilepticus after cardiopulmonary resuscitation (TELSTAR): study protocol for a randomized controlled trial","volume":"15","author":"Ruijter","year":"2014","journal-title":"Trials"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0150","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1002\/epi4.12318","article-title":"Interictal epileptogenic zone localization in patients with focal epilepsy using electric source imaging and directed functional connectivity from low-density EEG","volume":"4","author":"Coito","year":"2019","journal-title":"Epilepsia Open"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0155","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1002\/epi4.12066","article-title":"Automated long-term EEG analysis to localize the epileptogenic zone","volume":"2","author":"van Mierlo","year":"2017","journal-title":"Epilepsia Open"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0160","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.nicl.2017.09.011","article-title":"EEG source connectivity to localize the seizure onset zone in patients with drug resistant epilepsy","volume":"16","author":"Staljanssens","year":"2017","journal-title":"NeuroImage Clin"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0165","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1111\/epi.13228","article-title":"The diagnostic utility of 3D electroencephalography source imaging in pediatric epilepsy surgery","volume":"57","author":"Russo","year":"2016","journal-title":"Epilepsia"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0170","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1111\/ene.13676","article-title":"Ictal and interictal electric source imaging in pre-surgical evaluation: a prospective study","volume":"25","author":"Sharma","year":"2018","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0175","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fneur.2019.01250","article-title":"Accuracy of interictal and ictal electric and magnetic source imaging: a systematic review and meta-analysis","volume":"10","author":"Sharma","year":"2019","journal-title":"Front Neurol"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0180","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1111\/epi.12512","article-title":"Simultaneous subdural and scalp EEG correlates of frontal lobe epileptic sources","volume":"55","author":"Ramantani","year":"2014","journal-title":"Epilepsia"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0185","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1111\/j.1528-1167.2005.11404.x","article-title":"Intracranial EEG substrates of scalp EEG interictal spikes","volume":"46","author":"Tao","year":"2005","journal-title":"Epilepsia"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0190","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41467-019-08725-w","article-title":"Subcortical electrophysiological activity is detectable with high-density EEG source imaging","volume":"10","author":"Seeber","year":"2019","journal-title":"Nat Commun"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0195","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1016\/j.clinph.2012.10.022","article-title":"On noninvasive source imaging of the human K-complex","volume":"124","author":"Wennberg","year":"2013","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.resuscitation.2020.07.030_bib0200","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1016\/j.neuroimage.2006.02.016","article-title":"EEG-fMRI of idiopathic and secondarily generalized epilepsies","volume":"31","author":"Hamandi","year":"2006","journal-title":"Neuroimage"}],"container-title":["Resuscitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300957220303075?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300957220303075?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T03:14:06Z","timestamp":1759547646000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300957220303075"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10]]},"references-count":40,"alternative-id":["S0300957220303075"],"URL":"https:\/\/doi.org\/10.1016\/j.resuscitation.2020.07.030","relation":{},"ISSN":["0300-9572"],"issn-type":[{"value":"0300-9572","type":"print"}],"subject":[],"published":{"date-parts":[[2020,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Brain networks involved in generalized periodic discharges (GPD) in post-anoxic-ischemic encephalopathy","name":"articletitle","label":"Article Title"},{"value":"Resuscitation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.resuscitation.2020.07.030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}