{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T02:40:59Z","timestamp":1791081659280,"version":"4.1.0"},"reference-count":131,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,10,15]],"date-time":"2022-10-15T00:00:00Z","timestamp":1665792000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Regenerative Therapy"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.reth.2022.10.005","type":"journal-article","created":{"date-parts":[[2022,10,31]],"date-time":"2022-10-31T12:53:42Z","timestamp":1667220822000},"page":"527-539","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":119,"special_numbering":"C","title":["Regenerative medicine strategies for hair growth and regeneration: A narrative review of literature"],"prefix":"10.1016","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2528-2003","authenticated-orcid":false,"given":"Yusuke","family":"Shimizu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward Hosea","family":"Ntege","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Sunami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4618-2669","authenticated-orcid":false,"given":"Yoshikazu","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.reth.2022.10.005_bib1","series-title":"Ethnic skin and hair and other cultural considerations","first-page":"23","article-title":"Biology of hair","author":"Dawson","year":"2021"},{"key":"10.1016\/j.reth.2022.10.005_bib2","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1242\/jcs.02793","article-title":"The hair cycle","volume":"119","author":"Alonso","year":"2006","journal-title":"J\u00a0Cell Sci"},{"issue":"1\u20133","key":"10.1016\/j.reth.2022.10.005_bib3","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0379-0738(93)90255-9","article-title":"Anatomy and physiology of hair","volume":"63","author":"Harkey","year":"1993","journal-title":"Forensic Sci Int"},{"issue":"6","key":"10.1016\/j.reth.2022.10.005_bib4","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1046\/j.1523-1747.1999.00797.x","article-title":"Differences in hair follicle dermal papilla volume are due to extracellular matrix volume and cell number: implications for the control of hair follicle size and androgen responses","volume":"113","author":"Elliott","year":"1999","journal-title":"J\u00a0Invest Dermatol"},{"issue":"1","key":"10.1016\/j.reth.2022.10.005_bib5","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1038\/s41392-020-00441-y","article-title":"Functional hair follicle regeneration: an updated review","volume":"6","author":"Ji","year":"2021","journal-title":"Signal Transduct Targeted Ther"},{"issue":"3","key":"10.1016\/j.reth.2022.10.005_bib6","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1517\/14712598.2013.739601","article-title":"Therapeutic strategy for hair regeneration: hair cycle activation, niche environment modulation, wound-induced follicle neogenesis, and stem cell engineering","volume":"13","author":"Chueh","year":"2013","journal-title":"Expet Opin Biol Ther"},{"issue":"11","key":"10.1016\/j.reth.2022.10.005_bib7","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1185\/030079905X61820","article-title":"The psychosocial impact of hair loss among men: a multinational European study","volume":"21","author":"Alfonso","year":"2005","journal-title":"Curr Med Res Opin"},{"issue":"8","key":"10.1016\/j.reth.2022.10.005_bib8","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1001\/jama.1993.03500080046030","article-title":"A\u00a0case-control study of baldness in relation to myocardial infarction in men","volume":"269","author":"Lesko","year":"1993","journal-title":"JAMA"},{"key":"10.1016\/j.reth.2022.10.005_bib9","doi-asserted-by":"crossref","first-page":"485","DOI":"10.2147\/CCID.S284435","article-title":"Topical treatment for scarring and non-scarring alopecia: an overview of the current evidence","volume":"14","author":"Cardoso","year":"2021","journal-title":"Clin Cosmet Invest Dermatol"},{"key":"10.1016\/j.reth.2022.10.005_bib10","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1159\/000369407","article-title":"Primary scarring alopecias","volume":"47","author":"Rigopoulos","year":"2015","journal-title":"Curr Probl Dermatol"},{"issue":"1","key":"10.1016\/j.reth.2022.10.005_bib11","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/j.1346-8138.2011.01416.x","article-title":"Primary cicatricial alopecia: recent advances in understanding and management","volume":"39","author":"Ohyama","year":"2012","journal-title":"J\u00a0Dermatol"},{"issue":"4S","key":"10.1016\/j.reth.2022.10.005_bib12","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1016\/j.jid.2020.11.009","article-title":"Age-related changes in female scalp dermal sheath and dermal fibroblasts: how the hair follicle environment impacts hair aging","volume":"141","author":"Williams","year":"2021","journal-title":"J\u00a0Invest Dermatol"},{"issue":"3","key":"10.1016\/j.reth.2022.10.005_bib13","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1111\/ced.14982","article-title":"Anagen effluvium and the role of trichoscopy","volume":"47","author":"Starace","year":"2022","journal-title":"Clin Exp Dermatol"},{"key":"10.1016\/j.reth.2022.10.005_bib14","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1001\/archderm.1961.01580080005001","article-title":"Pathologic dynamics of human hair loss. I. Telogen effluvium","volume":"83","author":"Kligman","year":"1961","journal-title":"Arch Dermatol"},{"issue":"5","key":"10.1016\/j.reth.2022.10.005_bib15","article-title":"Telogen effluvium: a review of the literature","volume":"12","author":"Asghar","year":"2020","journal-title":"Cureus"},{"issue":"9","key":"10.1016\/j.reth.2022.10.005_bib16","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1177\/0961203310373938","article-title":"Involvement of scalp and nails in lupus erythematosus","volume":"19","author":"Tr\u00fceb","year":"2010","journal-title":"Lupus"},{"issue":"2","key":"10.1016\/j.reth.2022.10.005_bib17","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1007\/s11682-021-00533-5","article-title":"Reward processing in trichotillomania and skin picking disorder","volume":"16","author":"Grant","year":"2022","journal-title":"Brain Imag Behav"},{"issue":"1","key":"10.1016\/j.reth.2022.10.005_bib18","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.janxdis.2010.08.007","article-title":"The Skin Picking Impact Project: phenomenology, interference, and treatment utilization of pathological skin picking in a population-based sample","volume":"25","author":"Tucker","year":"2011","journal-title":"J\u00a0Anxiety Disord"},{"key":"10.1016\/j.reth.2022.10.005_bib19","doi-asserted-by":"crossref","first-page":"149","DOI":"10.2147\/CCID.S137296","article-title":"Traction alopecia: the root of the problem","volume":"11","author":"Billero","year":"2018","journal-title":"Clin Cosmet Invest Dermatol"},{"issue":"1","key":"10.1016\/j.reth.2022.10.005_bib20","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1159\/000504233","article-title":"Pressure-induced alopecia: presence of thin hairs as a trichoscopic clue for the diagnosis","volume":"6","author":"Tortelly","year":"2020","journal-title":"Skin Appendage Disord"},{"issue":"10","key":"10.1016\/j.reth.2022.10.005_bib21","doi-asserted-by":"crossref","first-page":"e599","DOI":"10.1111\/jdv.16480","article-title":"Trichoscopic and imaging study of lipedematous alopecia: report of five cases","volume":"34","author":"Doche","year":"2020","journal-title":"J\u00a0Eur Acad Dermatol Venereol"},{"issue":"1","key":"10.1016\/j.reth.2022.10.005_bib22","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/jdv.14624","article-title":"Evidence-based (S3) guideline for the treatment of androgenetic alopecia in women and men - short version","volume":"32","author":"Kanti","year":"2018","journal-title":"J\u00a0Eur Acad Dermatol Venereol"},{"issue":"11","key":"10.1016\/j.reth.2022.10.005_bib23","first-page":"s135","article-title":"New insight into the pathophysiology of hair loss trigger a paradigm shift in the treatment approach","volume":"16","author":"Sadick","year":"2017","journal-title":"J\u00a0Drugs Dermatol JDD"},{"issue":"12","key":"10.1016\/j.reth.2022.10.005_bib24","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.1111\/jdv.15081","article-title":"Efficacy of non-surgical treatments for androgenetic alopecia: a systematic review and network meta-analysis","volume":"32","author":"Gupta","year":"2018","journal-title":"J\u00a0Eur Acad Dermatol Venereol"},{"issue":"5","key":"10.1016\/j.reth.2022.10.005_bib25","first-page":"641","article-title":"Hair diameter diversity: a clinical sign reflecting the follicle miniaturization","volume":"137","author":"de Lacharri\u00e8re","year":"2001","journal-title":"Arch Dermatol"},{"issue":"5","key":"10.1016\/j.reth.2022.10.005_bib26","doi-asserted-by":"crossref","DOI":"10.1111\/dth.13059","article-title":"Physiopathology and current treatments of androgenetic alopecia: going beyond androgens and anti-androgens","volume":"32","author":"Katzer","year":"2019","journal-title":"Dermatol Ther"},{"issue":"8","key":"10.1016\/j.reth.2022.10.005_bib27","doi-asserted-by":"crossref","first-page":"2702","DOI":"10.3390\/ijms21082702","article-title":"Systematic review of platelet-rich plasma use in androgenetic alopecia compared with Minoxidil\u00ae, Finasteride\u00ae, and adult stem cell-based therapy","volume":"21","author":"Gentile","year":"2020","journal-title":"Int J Mol Sci"},{"issue":"1","key":"10.1016\/j.reth.2022.10.005_bib28","doi-asserted-by":"crossref","first-page":"119","DOI":"10.5114\/ada.2019.81685","article-title":"The impact of oxidative stress in androgenic alopecia in women","volume":"37","author":"Cwynar","year":"2020","journal-title":"Postepy Dermatol Alergol"},{"issue":"4","key":"10.1016\/j.reth.2022.10.005_bib29","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1038\/jid.2013.464","article-title":"Lifetime incidence risk of alopecia areata estimated at 2.1% by Rochester Epidemiology Project, 1990-2009","volume":"134","author":"Mirzoyev","year":"2014","journal-title":"J\u00a0Invest Dermatol"},{"issue":"1","key":"10.1016\/j.reth.2022.10.005_bib30","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.jid.2019.03.1142","article-title":"Harnessing the power of regenerative therapy for vitiligo and alopecia areata","volume":"140","author":"Barbulescu","year":"2020","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.reth.2022.10.005_bib31","article-title":"Immunomodulatory effect of MSCs and MSCs-derived extracellular vesicles in systemic lupus erythematosus","volume":"12","author":"Yang","year":"2021","journal-title":"Front Immunol"},{"issue":"1","key":"10.1016\/j.reth.2022.10.005_bib32","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s00005-021-00603-y","article-title":"Functional characteristics and application of mesenchymal stem cells in systemic lupus erythematosus","volume":"69","author":"Tang","year":"2021","journal-title":"Arch Immunol Ther Exp"},{"issue":"6","key":"10.1016\/j.reth.2022.10.005_bib33","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1111\/ced.12556","article-title":"Investigation of oxidative stress in patients with alopecia areata and its relationship with disease severity, duration, recurrence, and pattern","volume":"40","author":"Yenin","year":"2015","journal-title":"Clin Exp Dermatol"},{"issue":"1","key":"10.1016\/j.reth.2022.10.005_bib34","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1007\/s12016-017-8620-9","article-title":"Alopecia areata: a comprehensive review of pathogenesis and management","volume":"54","author":"Tr\u00fceb","year":"2018","journal-title":"Clin Rev Allergy Immunol"},{"issue":"1","key":"10.1016\/j.reth.2022.10.005_bib35","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.jaad.2008.03.031","article-title":"The role of scalp dermoscopy in the diagnosis of alopecia areata incognita","volume":"59","author":"Tosti","year":"2008","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"4","key":"10.1016\/j.reth.2022.10.005_bib36","first-page":"356","article-title":"Diagnosing and treating hair loss","volume":"80","author":"Mounsey","year":"2009","journal-title":"Am Fam Physician"},{"key":"10.1016\/j.reth.2022.10.005_bib37","doi-asserted-by":"crossref","unstructured":"Rudnicka L, Olszewska M, Rakowska A, Czuwara J. Alopecia areata. In: Atlas of trichoscopy. 2012th ed. London: Springer; p. 205\u2013220.","DOI":"10.1007\/978-1-4471-4486-1_16"},{"issue":"5","key":"10.1016\/j.reth.2022.10.005_bib38","doi-asserted-by":"crossref","first-page":"563","DOI":"10.4103\/0378-6323.116725","article-title":"Alopecia areata: an update","volume":"79","author":"Seetharam","year":"2013","journal-title":"Indian J Dermatol Venereol Leprol"},{"issue":"2","key":"10.1016\/j.reth.2022.10.005_bib39","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1159\/000492035","article-title":"Complementary and alternative treatments for alopecia: a comprehensive review","volume":"5","author":"Hosking","year":"2019","journal-title":"Skin Appendage Disord"},{"issue":"1","key":"10.1016\/j.reth.2022.10.005_bib40","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.jaad.2017.02.054","article-title":"The effectiveness of treatments for androgenetic alopecia: a systematic review and meta-analysis","volume":"77","author":"Adil","year":"2017","journal-title":"J\u00a0Am Acad Dermatol"},{"key":"10.1016\/j.reth.2022.10.005_bib41","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.jconrel.2020.06.019","article-title":"Controlled drug delivery for alopecia: a review","volume":"325","author":"Salim","year":"2020","journal-title":"J\u00a0Contr Release"},{"issue":"8","key":"10.1016\/j.reth.2022.10.005_bib42","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1111\/1346-8138.15902","article-title":"Hair regrowth in cicatricial alopecia: a literature review","volume":"48","author":"Poliner","year":"2021","journal-title":"J\u00a0Dermatol"},{"issue":"1","key":"10.1016\/j.reth.2022.10.005_bib43","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.jaad.2020.03.004","article-title":"The Alopecia Areata Consensus of Experts (ACE) study: results of an international expert opinion on treatments for alopecia areata","volume":"83","author":"Meah","year":"2020","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"6","key":"10.1016\/j.reth.2022.10.005_bib44","doi-asserted-by":"crossref","first-page":"655","DOI":"10.4187\/respcare.06314","article-title":"Clinical pharmacology of corticosteroids","volume":"63","author":"Williams","year":"2018","journal-title":"Respir Care"},{"issue":"6","key":"10.1016\/j.reth.2022.10.005_bib45","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1016\/j.jaad.2021.02.054","article-title":"Safety of low-dose oral minoxidil for hair loss: a multicenter study of 1404 patients","volume":"84","author":"Va\u00f1\u00f3-Galv\u00e1n","year":"2021","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"3","key":"10.1016\/j.reth.2022.10.005_bib46","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/j.jaad.2020.06.1009","article-title":"Oral minoxidil treatment for hair loss: a review of efficacy and safety","volume":"84","author":"Randolph","year":"2021","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"2","key":"10.1016\/j.reth.2022.10.005_bib47","doi-asserted-by":"crossref","first-page":"130","DOI":"10.2174\/187221312800166859","article-title":"Minoxidil use in dermatology, side effects and recent patents","volume":"6","author":"Rossi","year":"2012","journal-title":"Recent Pat Inflamm Allergy Drug Discov"},{"issue":"2","key":"10.1016\/j.reth.2022.10.005_bib48","doi-asserted-by":"crossref","first-page":"128","DOI":"10.4103\/0378-6323.177432","article-title":"Guidelines on the use of finasteride in androgenetic alopecia","volume":"82","author":"Mysore","year":"2016","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"10.1016\/j.reth.2022.10.005_bib49","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.reth.2020.01.004","article-title":"Advances in regenerative therapy: a review of the literature and future directions","volume":"14","author":"Ntege","year":"2020","journal-title":"Regen Ther"},{"key":"10.1016\/j.reth.2022.10.005_bib50","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.reth.2022.05.008","article-title":"Current regenerative medicine-based approaches for skin regeneration: a review of the literature and a report on clinical applications in Japan","volume":"21","author":"Shimizu","year":"2022","journal-title":"Regen Ther"},{"issue":"1","key":"10.1016\/j.reth.2022.10.005_bib51","doi-asserted-by":"crossref","first-page":"54","DOI":"10.3390\/cells10010054","article-title":"Role of human mesenchymal stem cells in regenerative therapy","volume":"10","author":"Vasanthan","year":"2020","journal-title":"Cells"},{"issue":"5","key":"10.1016\/j.reth.2022.10.005_bib52","doi-asserted-by":"crossref","first-page":"466","DOI":"10.3390\/cells8050466","article-title":"Advances in regenerative stem cell therapy in androgenic alopecia and hair loss: Wnt pathway, growth-factor, and mesenchymal stem cell signaling impact analysis on cell growth and hair follicle development","volume":"8","author":"Gentile","year":"2019","journal-title":"Cells"},{"key":"10.1016\/j.reth.2022.10.005_bib53","article-title":"Advances in stem cell-based therapy for hair loss","volume":"8","author":"Egger","year":"2020","journal-title":"CellR4 Repair Replace Regen Reprogram"},{"issue":"4","key":"10.1016\/j.reth.2022.10.005_bib54","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1038\/nm0405-367","article-title":"Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells","volume":"11","author":"Gnecchi","year":"2005","journal-title":"Nat Med"},{"issue":"5\u20138","key":"10.1016\/j.reth.2022.10.005_bib55","article-title":"Mesenchymal stem cell therapy for the treatment of inflammatory diseases: challenges, opportunities, and future perspectives","volume":"98","author":"Regmi","year":"2019","journal-title":"Eur J Cell Biol"},{"issue":"6","key":"10.1016\/j.reth.2022.10.005_bib56","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1016\/j.stemcr.2021.05.012","article-title":"ISSCR guidelines for stem cell research and clinical translation: the 2021 update","volume":"16","author":"Lovell-Badge","year":"2021","journal-title":"Stem Cell Rep"},{"issue":"4","key":"10.1016\/j.reth.2022.10.005_bib57","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.stem.2015.03.012","article-title":"New Japanese initiatives on stem cell therapies","volume":"16","author":"Konomi","year":"2015","journal-title":"Cell Stem Cell"},{"issue":"6","key":"10.1016\/j.reth.2022.10.005_bib58","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1097\/PRS.0b013e31824ecae6","article-title":"Human adipose stem cells: current clinical applications","volume":"129","author":"Gir","year":"2012","journal-title":"Plast Reconstr Surg"},{"issue":"14","key":"10.1016\/j.reth.2022.10.005_bib59","doi-asserted-by":"crossref","first-page":"4982","DOI":"10.3390\/ijms21144982","article-title":"Systematic review: allogenic use of stromal vascular fraction (SVF) and decellularized extracellular matrices (ECM) as advanced therapy medicinal products (ATMP) in tissue regeneration","volume":"21","author":"Gentile","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.reth.2022.10.005_bib60","series-title":"Cell therapy","first-page":"57","article-title":"Australian cellular therapy regulations","author":"Bell","year":"2022"},{"key":"10.1016\/j.reth.2022.10.005_bib61","first-page":"268","article-title":"Adipose derived stem cells and growth factors applied on hair transplantation. Follow-up of clinical outcome","volume":"4","author":"Zanzottera","year":"2014","journal-title":"J.\u00a0Cosmet. Dermatol. Sci. Appl."},{"issue":"5","key":"10.1016\/j.reth.2022.10.005_bib62","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1080\/09546634.2016.1227419","article-title":"Stem cell therapy as a novel therapeutic intervention for resistant cases of alopecia areata and androgenetic alopecia","volume":"29","author":"Elmaadawi","year":"2018","journal-title":"J\u00a0Dermatol Treat"},{"issue":"2","key":"10.1016\/j.reth.2022.10.005_bib63","doi-asserted-by":"crossref","first-page":"408","DOI":"10.3390\/ijms18020408","article-title":"Evaluation of not-activated and activated PRP in hair loss treatment: role of growth factor and cytokine concentrations obtained by different collection systems","volume":"18","author":"Gentile","year":"2017","journal-title":"Int J Mol Sci"},{"issue":"1","key":"10.1016\/j.reth.2022.10.005_bib64","doi-asserted-by":"crossref","first-page":"6","DOI":"10.3390\/genes12010006","article-title":"Current status and future prospects of perinatal stem cells","volume":"12","author":"Torre","year":"2020","journal-title":"Genes (Basel)."},{"key":"10.1016\/j.reth.2022.10.005_bib65","article-title":"Generation and applications of induced pluripotent stem cell-derived mesenchymal stem cells","volume":"2018","author":"Zhao","year":"2018","journal-title":"Stem Cell Int"},{"key":"10.1016\/j.reth.2022.10.005_bib66","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/4740709","article-title":"The use of adipose-derived stem cells in selected skin diseases (vitiligo, alopecia, and nonhealing wounds)","author":"Owczarczyk-Saczonek","year":"2017","journal-title":"Stem Cell Int"},{"issue":"15","key":"10.1016\/j.reth.2022.10.005_bib67","doi-asserted-by":"crossref","first-page":"2300","DOI":"10.3390\/cells11152300","article-title":"Mesenchymal stem cell-derived secretome: a potential therapeutic option for autoimmune and immune-mediated inflammatory diseases","volume":"11","author":"M\u0171zes","year":"2022","journal-title":"Cells"},{"issue":"9","key":"10.1016\/j.reth.2022.10.005_bib68","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/j.tips.2020.06.009","article-title":"Mesenchymal stem cell immunomodulation: mechanisms and therapeutic potential","volume":"41","author":"Song","year":"2020","journal-title":"Trends Pharmacol Sci"},{"issue":"1","key":"10.1016\/j.reth.2022.10.005_bib69","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1038\/s41467-019-10491-8","article-title":"Mesenchymal stem cell therapy induces FLT3L and CD1c+ dendritic cells in systemic lupus erythematosus patients","volume":"10","author":"Yuan","year":"2019","journal-title":"Nat Commun"},{"issue":"2","key":"10.1016\/j.reth.2022.10.005_bib70","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1634\/stemcells.2007-0528","article-title":"Bone marrow-derived mesenchymal stem cells induce both polyclonal expansion and differentiation of B cells isolated from healthy donors and systemic lupus erythematosus patients","volume":"26","author":"Traggiai","year":"2008","journal-title":"Stem Cell"},{"key":"10.1016\/j.reth.2022.10.005_bib71","first-page":"A46","article-title":"CT-04 Safety and efficacy of allogeneic umbilical cord-derived mesenchymal stem cells (MSCs) in patients with systemic lupus erythematosus: results of an open-label phase I study","volume":"5","author":"Kamen","year":"2018","journal-title":"Lupus Sci Med"},{"issue":"8","key":"10.1016\/j.reth.2022.10.005_bib72","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1136\/ard.2009.123463","article-title":"Allogenic mesenchymal stem cells transplantation in refractory systemic lupus erythematosus: a pilot clinical study","volume":"69","author":"Liang","year":"2010","journal-title":"Ann Rheum Dis"},{"issue":"11","key":"10.1016\/j.reth.2022.10.005_bib73","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1177\/0961203315583541","article-title":"Combined transplantation of autologous hematopoietic stem cells and allogeneic mesenchymal stem cells increases T regulatory cells in systemic lupus erythematosus with refractory lupus nephritis and leukopenia","volume":"24","author":"Wang","year":"2015","journal-title":"Lupus"},{"issue":"3","key":"10.1016\/j.reth.2022.10.005_bib74","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/j.stemcr.2018.01.029","article-title":"A\u00a0long-term follow-up study of allogeneic mesenchymal stem\/stromal cell transplantation in patients with drug-resistant systemic lupus erythematosus","volume":"10","author":"Wang","year":"2018","journal-title":"Stem Cell Rep"},{"issue":"13","key":"10.1016\/j.reth.2022.10.005_bib75","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.1177\/0961203318804922","article-title":"Therapeutic potential of allogeneic mesenchymal stromal cells transplantation for lupus nephritis","volume":"27","author":"Barbado","year":"2018","journal-title":"Lupus"},{"issue":"7","key":"10.1016\/j.reth.2022.10.005_bib76","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1177\/0961203318768889","article-title":"Mesenchymal stem cell transplantation in systemic lupus erythematous, a mesenchymal stem cell disorder","volume":"27","author":"Fathollahi","year":"2018","journal-title":"Lupus"},{"key":"10.1016\/j.reth.2022.10.005_bib77","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1172\/JCI113979","article-title":"Induction of excessive B cell proliferation and differentiation by an in\u00a0vitro stimulus in culture in human systemic lupus erythematosus","volume":"83","author":"Suzuki","year":"1989","journal-title":"J\u00a0Clin Invest"},{"issue":"7","key":"10.1016\/j.reth.2022.10.005_bib78","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1002\/stem.2638","article-title":"Human iPSC-MSC-derived xenografts modulate immune responses by inhibiting the cleavage of caspases","volume":"35","author":"Li","year":"2017","journal-title":"Stem Cell"},{"issue":"5","key":"10.1016\/j.reth.2022.10.005_bib79","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1038\/cmi.2015.89","article-title":"The regulation of the Treg\/Th17 balance by mesenchymal stem cells in human systemic lupus erythematosus","volume":"14","author":"Wang","year":"2017","journal-title":"Cell Mol Immunol"},{"key":"10.1016\/j.reth.2022.10.005_bib80","first-page":"1","article-title":"Hair follicle growth by stromal vascular fraction-enhanced adipose transplantation in baldness","volume":"10","author":"Perez-Meza","year":"2017","journal-title":"Stem Cells Cloning"},{"issue":"9","key":"10.1016\/j.reth.2022.10.005_bib81","doi-asserted-by":"crossref","first-page":"1836","DOI":"10.1016\/j.arthro.2015.03.014","article-title":"Umbilical cord tissue offers the greatest number of harvestable mesenchymal stem cells for research and clinical application: a literature review of different harvest sites","volume":"31","author":"Vangsness","year":"2015","journal-title":"Arthroscopy"},{"issue":"15","key":"10.1016\/j.reth.2022.10.005_bib82","doi-asserted-by":"crossref","first-page":"3741","DOI":"10.12998\/wjcc.v9.i15.3741","article-title":"Alopecia treatment using minimally manipulated human umbilical cord-derived mesenchymal stem cells: three case reports and review of the literature","volume":"9","author":"Ahn","year":"2021","journal-title":"World J Clin Cases"},{"key":"10.1016\/j.reth.2022.10.005_bib83","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/978-1-4939-1785-3_10","article-title":"Biological differences between native and cultured mesenchymal stem cells: implications for therapies","volume":"1235","author":"Jones","year":"2015","journal-title":"Methods Mol Biol"},{"issue":"6","key":"10.1016\/j.reth.2022.10.005_bib84","doi-asserted-by":"crossref","first-page":"5207","DOI":"10.3892\/mmr.2016.5169","article-title":"Changes in mesenchymal stem cells following long-term culture in\u00a0vitro","volume":"13","author":"Gu","year":"2016","journal-title":"Mol Med Rep"},{"issue":"5","key":"10.1016\/j.reth.2022.10.005_bib85","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1159\/000510152","article-title":"Maintaining hair inductivity in human dermal papilla cells: a review of effective methods","volume":"33","author":"Taghiabadi","year":"2020","journal-title":"Skin Pharmacol Physiol"},{"issue":"1","key":"10.1016\/j.reth.2022.10.005_bib86","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0116892","article-title":"Derivation of hair-inducing cells from human pluripotent stem cells","volume":"10","author":"Gnedeva","year":"2015","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.reth.2022.10.005_bib87","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.jaad.2020.02.033","article-title":"Autologous cell-based therapy for male and female pattern hair loss using dermal sheath cup cells: a randomized placebo-controlled double-blinded dose-finding clinical study","volume":"83","author":"Tsuboi","year":"2020","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"4","key":"10.1016\/j.reth.2022.10.005_bib88","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.stem.2020.09.014","article-title":"Pluripotent stem cell-based cell therapy-promise and challenges","volume":"27","author":"Yamanaka","year":"2020","journal-title":"Cell Stem Cell"},{"issue":"6S","key":"10.1016\/j.reth.2022.10.005_bib89","doi-asserted-by":"crossref","first-page":"39S","DOI":"10.1097\/PRS.0000000000008785","article-title":"The rise of induced pluripotent stem cell approach to hair restoration","volume":"148","author":"Pinto","year":"2021","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.reth.2022.10.005_bib90","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/s41232-019-0093-1","article-title":"Use of human intra-tissue stem\/progenitor cells and induced pluripotent stem cells for hair follicle regeneration","volume":"39","author":"Ohyama","year":"2019","journal-title":"Inflamm Regen"},{"key":"10.1016\/j.reth.2022.10.005_bib91","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/s41232-019-0093-1","article-title":"Use of human intra-tissue stem\/progenitor cells and induced pluripotent stem cells for hair follicle regeneration","volume":"39","author":"Ohyama","year":"2019","journal-title":"Inflamm Regen"},{"key":"10.1016\/j.reth.2022.10.005_bib92","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2020.173197","article-title":"Current advances in stem cell-based therapies for hair regeneration","volume":"881","author":"Yuan","year":"2020","journal-title":"Eur J Pharmacol"},{"issue":"6","key":"10.1016\/j.reth.2022.10.005_bib93","doi-asserted-by":"crossref","DOI":"10.4161\/cib.26631","article-title":"Stem cell therapy without the cells","volume":"6","author":"Maguire","year":"2013","journal-title":"Commun Integr Biol"},{"issue":"4","key":"10.1016\/j.reth.2022.10.005_bib94","doi-asserted-by":"crossref","first-page":"307","DOI":"10.3390\/cells8040307","article-title":"Review of the isolation, characterization, biological function, and multifarious therapeutic approaches of exosomes","volume":"8","author":"Gurunathan","year":"2019","journal-title":"Cells"},{"issue":"3","key":"10.1016\/j.reth.2022.10.005_bib95","first-page":"295","article-title":"The role of adipose tissue in hair regeneration: a potential tool for management?","volume":"14","author":"Nepal","year":"2021","journal-title":"J\u00a0Cutan Aesthetic Surg"},{"issue":"2","key":"10.1016\/j.reth.2022.10.005_bib96","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.bbrc.2018.04.067","article-title":"Regulation of hair follicle development by exosomes derived from dermal papilla cells","volume":"500","author":"Zhou","year":"2018","journal-title":"Biochem Biophys Res Commun"},{"issue":"1","key":"10.1016\/j.reth.2022.10.005_bib97","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1186\/s13287-018-0939-5","article-title":"Exosomes derived from human adipose tissue-derived mesenchymal stem cells alleviate atopic dermatitis","volume":"9","author":"Cho","year":"2018","journal-title":"Stem Cell Res Ther"},{"issue":"10","key":"10.1016\/j.reth.2022.10.005_bib98","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.5966\/sctm.2015-0367","article-title":"Umbilical cord-derived mesenchymal stem cell-derived exosomal MicroRNAs suppress myofibroblast differentiation by inhibiting the transforming growth factor-\u03b2\/SMAD2 pathway during wound healing","volume":"5","author":"Fang","year":"2016","journal-title":"Stem Cells Transl Med"},{"issue":"7","key":"10.1016\/j.reth.2022.10.005_bib99","doi-asserted-by":"crossref","first-page":"2158","DOI":"10.1002\/stem.1771","article-title":"HucMSC-exosome mediated-Wnt4 signaling is required for cutaneous wound healing","volume":"33","author":"Zhang","year":"2015","journal-title":"Stem Cell"},{"issue":"6","key":"10.1016\/j.reth.2022.10.005_bib100","doi-asserted-by":"crossref","first-page":"6670","DOI":"10.1021\/acsnano.9b01004","article-title":"Stem cell-derived exosomes as nanotherapeutics for autoimmune and neurodegenerative disorders","volume":"13","author":"Riazifar","year":"2019","journal-title":"ACS Nano"},{"issue":"4","key":"10.1016\/j.reth.2022.10.005_bib101","doi-asserted-by":"crossref","first-page":"856","DOI":"10.3390\/cells9040856","article-title":"Macrophage-derived extracellular vesicle promotes hair growth","volume":"9","author":"Rajendran","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.reth.2022.10.005_bib102","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s13770-013-0010-7","article-title":"Mesenchymal stem cell-derived secretome and microvesicles as a cell-free therapeutics for neurodegenerative disorders","volume":"10","author":"Kim","year":"2013","journal-title":"Tissue Eng Regen Med"},{"issue":"2","key":"10.1016\/j.reth.2022.10.005_bib103","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1167\/iovs.14-15859","article-title":"Corneal epithelial wound healing and bactericidal effect of conditioned medium from human uterine cervical stem cells","volume":"56","author":"Bermudez","year":"2015","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"1","key":"10.1016\/j.reth.2022.10.005_bib104","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1186\/s13287-020-01777-6","article-title":"Extracellular vesicles from adipose-derived stem cells ameliorate ultraviolet B-induced skin photoaging by attenuating reactive oxygen species production and inflammation","volume":"11","author":"Xu","year":"2020","journal-title":"Stem Cell Res Ther"},{"key":"10.1016\/j.reth.2022.10.005_bib105","doi-asserted-by":"crossref","first-page":"273","DOI":"10.5992\/AJCS-D-12-00015.1","article-title":"The latest advance in hair regeneration therapy using proteins secreted by adipose-derived stem cells","volume":"29","author":"Fukuoka","year":"2012","journal-title":"Am J Cosmet Surg"},{"key":"10.1016\/j.reth.2022.10.005_bib106","first-page":"e10","article-title":"Hair regeneration treatment using adipose-derived stem cell conditioned medium: follow-up with trichograms","volume":"15","author":"Fukuoka","year":"2015","journal-title":"Eplasty"},{"issue":"6","key":"10.1016\/j.reth.2022.10.005_bib107","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1111\/ijd.12650","article-title":"Clinical use of conditioned media of adipose tissue-derived stem cells in female pattern hair loss: a retrospective case series study","volume":"54","author":"Shin","year":"2015","journal-title":"Int J Dermatol"},{"issue":"6","key":"10.1016\/j.reth.2022.10.005_bib108","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1097\/DSS.0000000000002128","article-title":"Sequential scalp assessment in hair regeneration therapy using an adipose-derived stem cell-conditioned medium","volume":"46","author":"Narita","year":"2020","journal-title":"Dermatol Surg"},{"key":"10.1016\/j.reth.2022.10.005_bib109","first-page":"45","article-title":"Mesotherapy \u2013 a nonsurgicalnonsurgicalnonsurgical cosmetic medicine treatment: a review","volume":"4","author":"Raghvendra","year":"2010","journal-title":"Int J Pharmaceut Sci Rev Res"},{"key":"10.1016\/j.reth.2022.10.005_bib110","doi-asserted-by":"crossref","DOI":"10.1111\/jocd.14900","article-title":"Current application of mesotherapy in pattern hair loss: a systematic review","author":"Tang","year":"2022","journal-title":"J\u00a0Cosmet Dermatol"},{"issue":"6","key":"10.1016\/j.reth.2022.10.005_bib111","first-page":"NP328","article-title":"Cell enriched autologous fat grafts to follicular niche improves hair regrowth in early androgenetic alopecia","volume":"40","author":"Kuka","year":"2020","journal-title":"Aesthetic Surg J"},{"issue":"7","key":"10.1016\/j.reth.2022.10.005_bib112","doi-asserted-by":"crossref","first-page":"531","DOI":"10.2174\/1574888X12666170522114307","article-title":"Hair regeneration therapy: application of adipose-derived stem cells","volume":"12","author":"Fukuoka","year":"2017","journal-title":"Curr Stem Cell Res Ther"},{"issue":"5","key":"10.1016\/j.reth.2022.10.005_bib113","doi-asserted-by":"crossref","first-page":"555","DOI":"10.4196\/kjpp.2018.22.5.555","article-title":"Human umbilical cord blood mesenchymal stem cells engineered to overexpress growth factors accelerate outcomes in hair growth","volume":"22","author":"Bak","year":"2018","journal-title":"Korean J Physiol Pharmacol"},{"key":"10.1016\/j.reth.2022.10.005_bib114","article-title":"An update on the potential of mesenchymal stem cell therapy for cutaneous diseases","volume":"2021","author":"Li","year":"2021","journal-title":"Stem Cell Int"},{"issue":"8","key":"10.1016\/j.reth.2022.10.005_bib115","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1080\/13543784.2017.1353598","article-title":"Experimental and early investigational drugs for androgenetic alopecia","volume":"26","author":"Guo","year":"2017","journal-title":"Expet Opin Invest Drugs"},{"issue":"2","key":"10.1016\/j.reth.2022.10.005_bib116","doi-asserted-by":"crossref","first-page":"634","DOI":"10.5966\/sctm.2016-0071","article-title":"Impact of the secretome of human mesenchymal stem cells on brain structure and animal behavior in a rat model of Parkinson's disease","volume":"6","author":"Teixeira","year":"2017","journal-title":"Stem Cells Transl Med"},{"issue":"3","key":"10.1016\/j.reth.2022.10.005_bib117","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1111\/jocd.12331","article-title":"Platelet-rich plasma for androgenetic alopecia: does it work? Evidence from meta analysis","volume":"16","author":"Giordano","year":"2017","journal-title":"J\u00a0Cosmet Dermatol"},{"issue":"3","key":"10.1016\/j.reth.2022.10.005_bib118","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1111\/jocd.14662","article-title":"Platelet-rich plasma in hair loss-Mechanism, preparation, and classification","volume":"21","author":"Alexander","year":"2022","journal-title":"J\u00a0Cosmet Dermatol"},{"issue":"7 Pt 1","key":"10.1016\/j.reth.2022.10.005_bib119","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1111\/j.1524-4725.2012.02394.x","article-title":"Autologous platelet-rich plasma: a potential therapeutic tool for promoting hair growth","volume":"38","author":"Li","year":"2012","journal-title":"Dermatol Surg"},{"issue":"2","key":"10.1016\/j.reth.2022.10.005_bib120","doi-asserted-by":"crossref","first-page":"27","DOI":"10.3390\/biomedicines7020027","article-title":"Platelet-rich plasma and micrografts enriched with autologous human follicle mesenchymal stem cells improve hair Re-growth in androgenetic alopecia. Biomolecular pathway analysis and clinical evaluation","volume":"7","author":"Gentile","year":"2019","journal-title":"Biomedicines"},{"issue":"1","key":"10.1016\/j.reth.2022.10.005_bib121","doi-asserted-by":"crossref","DOI":"10.1111\/dth.12437","article-title":"Platelets rich plasma versus minoxidil 5% in treatment of alopecia areata: a trichoscopy evaluation","volume":"30","author":"El Taieb","year":"2017","journal-title":"Dermatol Ther"},{"issue":"5","key":"10.1016\/j.reth.2022.10.005_bib122","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.jdcr.2015.07.004","article-title":"Successful treatment of corticosteroid-resistant ophiasis-type alopecia areata (AA) with platelet-rich plasma (PRP)","volume":"1","author":"Donovan","year":"2015","journal-title":"JAAD Case Rep"},{"issue":"5","key":"10.1016\/j.reth.2022.10.005_bib123","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1111\/jocd.13149","article-title":"Stromal vascular fraction-enriched platelet-rich plasma therapy reverses the effects of androgenetic alopecia","volume":"19","author":"Butt","year":"2020","journal-title":"J\u00a0Cosmet Dermatol"},{"issue":"8","key":"10.1016\/j.reth.2022.10.005_bib124","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1093\/asj\/sjy029","article-title":"Introducing platelet-rich stroma: platelet-rich plasma (PRP) and stromal vascular fraction (SVF) combined for the treatment of androgenetic alopecia","volume":"38","author":"Stevens","year":"2018","journal-title":"Aesthetic Surg J"},{"issue":"11","key":"10.1016\/j.reth.2022.10.005_bib125","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.5966\/sctm.2015-0107","article-title":"The effect of platelet-rich plasma in hair regrowth: a randomized placebo-controlled trial","volume":"4","author":"Gentile","year":"2015","journal-title":"Stem Cells Transl Med"},{"issue":"7","key":"10.1016\/j.reth.2022.10.005_bib126","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.2174\/138920112800624382","article-title":"Do the fibrin architecture and leukocyte content influence the growth factor release of platelet concentrates? An evidence-based answer comparing a pure platelet-rich plasma (P-PRP) gel and a leukocyte- and platelet-rich fibrin (L-PRF)","volume":"13","author":"Dohan Ehrenfest","year":"2012","journal-title":"Curr Pharmaceut Biotechnol"},{"issue":"4","key":"10.1016\/j.reth.2022.10.005_bib127","doi-asserted-by":"crossref","first-page":"924","DOI":"10.3390\/cells9040924","article-title":"Mesenchymal stromal cell secretome for severe COVID-19 infections: premises for the therapeutic use","volume":"9","author":"Bari","year":"2020","journal-title":"Cells"},{"issue":"1","key":"10.1016\/j.reth.2022.10.005_bib128","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1002\/sctm.19-0114","article-title":"Mesenchymal stromal cell-derived extracellular vesicles for regenerative therapy and immune modulation: progress and challenges toward clinical application","volume":"9","author":"Allan","year":"2020","journal-title":"Stem Cells Transl Med"},{"key":"10.1016\/j.reth.2022.10.005_bib129","article-title":"Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper","volume":"4","author":"Lener","year":"2015","journal-title":"J\u00a0Extracell Vesicles"},{"issue":"1","key":"10.1016\/j.reth.2022.10.005_bib130","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1186\/s13287-015-0116-z","article-title":"Human bone marrow- and adipose-mesenchymal stem cells secrete exosomes enriched in distinctive miRNA and tRNA species","volume":"6","author":"Baglio","year":"2015","journal-title":"Stem Cell Res Ther"},{"issue":"8","key":"10.1016\/j.reth.2022.10.005_bib131","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.1016\/j.biotechadv.2018.09.001","article-title":"Towards rationally designed biomanufacturing of therapeutic extracellular vesicles: impact of the bioproduction microenvironment","volume":"36","author":"Patel","year":"2018","journal-title":"Biotechnol Adv"}],"container-title":["Regenerative Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S235232042200102X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S235232042200102X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T17:41:14Z","timestamp":1762450874000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S235232042200102X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":131,"alternative-id":["S235232042200102X"],"URL":"https:\/\/doi.org\/10.1016\/j.reth.2022.10.005","relation":{},"ISSN":["2352-3204"],"issn-type":[{"value":"2352-3204","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Regenerative medicine strategies for hair growth and regeneration: A narrative review of literature","name":"articletitle","label":"Article Title"},{"value":"Regenerative Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.reth.2022.10.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Japanese Society for Regenerative Medicine. Production and hosting by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}