{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T17:44:22Z","timestamp":1791567862240,"version":"4.3.4"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T00:00:00Z","timestamp":1725494400000},"content-version":"vor","delay-in-days":96,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["23K09024"],"award-info":[{"award-number":["23K09024"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["23H03060"],"award-info":[{"award-number":["23H03060"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Regenerative Therapy"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1016\/j.reth.2024.09.001","type":"journal-article","created":{"date-parts":[[2024,9,17]],"date-time":"2024-09-17T18:21:18Z","timestamp":1726597278000},"page":"819-825","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Status and prospects for the development of regenerative therapies for corneal and ocular diseases"],"prefix":"10.1016","volume":"26","author":[{"given":"Hiroshi","family":"Takayanagi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryuhei","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.reth.2024.09.001_bib1","first-page":"709","article-title":"Limbal autograft transplantation for chemical and thermal burns","volume":"96","author":"Kenyon","year":"1989","journal-title":"Dev Ophthalmol"},{"issue":"9057","key":"10.1016\/j.reth.2024.09.001_bib2","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1016\/S0140-6736(96)11188-0","article-title":"Long-term restoration of damaged corneal surfaces with autologous cultivated corneal epithelium","volume":"349","author":"Pellegrini","year":"1997","journal-title":"Lancet"},{"issue":"11","key":"10.1016\/j.reth.2024.09.001_bib3","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1097\/00007890-200012150-00009","article-title":"Long-term regeneration of human epidermis on third degree burns transplanted with autologous cultured epithelium grown on a fibrin matrix","volume":"70","author":"Ronfard","year":"2000","journal-title":"Transplantation"},{"issue":"2","key":"10.1016\/j.reth.2024.09.001_bib4","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1056\/NEJM200007133430202","article-title":"Reconstruction of damaged corneas by transplantation of autologous limbal epithelial cells","volume":"343","author":"Tsai","year":"2000","journal-title":"N\u00a0Engl J Med"},{"issue":"2","key":"10.1016\/j.reth.2024.09.001_bib5","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1056\/NEJMoa0905955","article-title":"Limbal stem-cell therapy and long-term corneal regeneration","volume":"363","author":"Rama","year":"2010","journal-title":"N\u00a0Engl J Med"},{"issue":"6","key":"10.1016\/j.reth.2024.09.001_bib6","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.ophtha.2023.01.016","article-title":"Clinical trial of autologous cultivated limbal epithelial cell sheet transplantation for patients with limbal stem cell deficiency","volume":"130","author":"Oie","year":"2023","journal-title":"Ophthalmology"},{"issue":"7 Suppl","key":"10.1016\/j.reth.2024.09.001_bib7","doi-asserted-by":"crossref","first-page":"S75","DOI":"10.1097\/00003226-200310001-00011","article-title":"Ocular surface reconstruction using cultivated mucosal epithelial stem cells","volume":"22","author":"Nakamura","year":"2003","journal-title":"Cornea"},{"issue":"1","key":"10.1016\/j.reth.2024.09.001_bib8","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1167\/iovs.02-0195","article-title":"The successful culture and autologous transplantation of rabbit oral mucosal epithelial cells on amniotic membrane","volume":"44","author":"Nakamura","year":"2003","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"10","key":"10.1016\/j.reth.2024.09.001_bib9","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1136\/bjo.2003.038497","article-title":"Transplantation of cultivated autologous oral mucosal epithelial cells in patients with severe ocular surface disorders","volume":"88","author":"Nakamura","year":"2004","journal-title":"Br J Ophthalmol"},{"issue":"12","key":"10.1016\/j.reth.2024.09.001_bib10","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1056\/NEJMoa040455","article-title":"Corneal reconstruction with tissue-engineered cell sheets composed of autologous oral mucosal epithelium","volume":"351","author":"Nishida","year":"2004","journal-title":"N\u00a0Engl J Med"},{"issue":"10","key":"10.1016\/j.reth.2024.09.001_bib11","doi-asserted-by":"crossref","first-page":"8926","DOI":"10.3390\/ijms24108926","article-title":"Early clinical outcomes of the first commercialized human autologous ex\u00a0vivo cultivated oral mucosal epithelial cell transplantation for limbal stem cell deficiency: two case reports and literature review","volume":"24","author":"Toshida","year":"2023","journal-title":"Int J Mol Sci"},{"issue":"9","key":"10.1016\/j.reth.2024.09.001_bib12","doi-asserted-by":"crossref","first-page":"5615","DOI":"10.1167\/iovs.11-9293","article-title":"Expression of angiogenesis-related factors in human corneas after cultivated oral mucosal epithelial transplantation","volume":"53","author":"Chen","year":"2012","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"14","key":"10.1016\/j.reth.2024.09.001_bib13","doi-asserted-by":"crossref","DOI":"10.3390\/ijms241411522","article-title":"Comparison between cultivated oral mucosa and ocular surface epithelia for COMET patients follow-up","volume":"24","author":"Attico","year":"2023","journal-title":"Int J Mol Sci"},{"issue":"7594","key":"10.1016\/j.reth.2024.09.001_bib14","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1038\/nature17000","article-title":"Co-ordinated ocular development from human iPS cells and recovery of corneal function","volume":"531","author":"Hayashi","year":"2016","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.reth.2024.09.001_bib15","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1038\/nprot.2017.007","article-title":"Coordinated generation of multiple ocular-like cell lineages and fabrication of functional corneal epithelial cell sheets from human iPS cells","volume":"12","author":"Hayashi","year":"2017","journal-title":"Nat Protoc"},{"issue":"23","key":"10.1016\/j.reth.2024.09.001_bib17","article-title":"Human Leukocyte antigen class I and II knockout human induced pluripotent stem cell-derived cells: universal donor for cell therapy","volume":"7","author":"Mattapally","year":"2018","journal-title":"J\u00a0Am Heart Assoc"},{"issue":"1","key":"10.1016\/j.reth.2024.09.001_bib18","first-page":"1","article-title":"Development of immunocompatible pluripotent stem cells via CRISPR-based human leukocyte antigen engineering","volume":"51","author":"Jang","year":"2019","journal-title":"Exp Mol Med"},{"issue":"4","key":"10.1016\/j.reth.2024.09.001_bib19","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/j.stem.2019.02.005","article-title":"Targeted disruption of HLA genes via CRISPR-Cas9 generates iPSCs with enhanced immune compatibility","volume":"24","author":"Xu","year":"2019","journal-title":"Cell Stem Cell"},{"issue":"1","key":"10.1016\/j.reth.2024.09.001_bib20","doi-asserted-by":"crossref","first-page":"8472","DOI":"10.1038\/s41598-020-65577-x","article-title":"Generation and characterization of HLA-universal platelets derived from induced pluripotent stem cells","volume":"10","author":"Norbnop","year":"2020","journal-title":"Sci Rep"},{"issue":"20","key":"10.1016\/j.reth.2024.09.001_bib21","article-title":"HLA DR genome editing with TALENs in human iPSCs produced immune-tolerant dendritic cells","volume":"2021","author":"Kwon","year":"2021","journal-title":"Stem Cell Int"},{"key":"10.1016\/j.reth.2024.09.001_bib22","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.omtm.2022.05.010","article-title":"Generation of hypoimmunogenic induced pluripotent stem cells by CRISPR-Cas9 system and detailed evaluation for clinical application","volume":"26","author":"Kitano","year":"2022","journal-title":"Mol Ther Methods Clin Dev"},{"issue":"1","key":"10.1016\/j.reth.2024.09.001_bib23","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/0039-6257(90)90048-Z","article-title":"Anterior chamber associated immune deviation: the privilege of immunity in the eye","volume":"35","author":"Streilein","year":"1990","journal-title":"Surv Ophthalmol"},{"issue":"8","key":"10.1016\/j.reth.2024.09.001_bib24","doi-asserted-by":"crossref","first-page":"3680","DOI":"10.1167\/iovs.08-2634","article-title":"Enhancement on primate corneal endothelial cell survival in\u00a0vitro by a ROCK inhibitor","volume":"50","author":"Okumura","year":"2009","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.reth.2024.09.001_bib25","doi-asserted-by":"crossref","first-page":"9167","DOI":"10.1038\/srep09167","article-title":"The effects of Rho-associated kinase inhibitor Y-27632 on primary human corneal endothelial cells propagated using a dual media approach","volume":"5","author":"Peh","year":"2015","journal-title":"Sci Rep"},{"issue":"15","key":"10.1016\/j.reth.2024.09.001_bib26","doi-asserted-by":"crossref","first-page":"6731","DOI":"10.1167\/iovs.16-20414","article-title":"Corneal endothelial cell migration and proliferation enhanced by rho kinase (ROCK) inhibitors in in\u00a0vitro and in\u00a0vivo models","volume":"57","author":"Meekins","year":"2016","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"11","key":"10.1016\/j.reth.2024.09.001_bib27","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1056\/NEJMoa1712770","article-title":"Injection of cultured cells with a ROCK inhibitor for bullous keratopathy","volume":"378","author":"Kinoshita","year":"2018","journal-title":"N\u00a0Engl J Med"},{"issue":"12","key":"10.1016\/j.reth.2024.09.001_bib28","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0145266","article-title":"Efficient generation of human embryonic stem cell-derived corneal endothelial cells by directed differentiation","volume":"10","author":"McCabe","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.reth.2024.09.001_bib29","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.exer.2016.08.004","article-title":"Directed differentiation of human embryonic stem cells to corneal endothelial cell-like cells: a transcriptomic analysis","volume":"151","author":"Song","year":"2016","journal-title":"Exp Eye Res"},{"issue":"15","key":"10.1016\/j.reth.2024.09.001_bib30","doi-asserted-by":"crossref","first-page":"6878","DOI":"10.1167\/iovs.16-20024","article-title":"Generation of human corneal endothelial cells via in\u00a0vitro ocular lineage restriction of pluripotent stem cells","volume":"57","author":"Zhao","year":"2016","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"5","key":"10.1016\/j.reth.2024.09.001_bib31","doi-asserted-by":"crossref","first-page":"bio032102","DOI":"10.1242\/bio.032102","article-title":"Feeder-free differentiation of cells exhibiting characteristics of corneal endothelium from human induced pluripotent stem cells","volume":"7","author":"Wagoner","year":"2018","journal-title":"Biol Open"},{"issue":"6","key":"10.1016\/j.reth.2024.09.001_bib32","doi-asserted-by":"crossref","first-page":"2437","DOI":"10.1167\/iovs.17-22927","article-title":"Generation and proteome profiling of PBMC-originated, iPSC-derived corneal endothelial cells","volume":"59","author":"Ali","year":"2018","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.reth.2024.09.001_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.scr.2021.102497","article-title":"Transplantation of iPSC-derived corneal endothelial substitutes in a monkey corneal edema model","volume":"55","author":"Hatou","year":"2021","journal-title":"Stem Cell Res"},{"issue":"1","key":"10.1016\/j.reth.2024.09.001_bib34","doi-asserted-by":"crossref","DOI":"10.1172\/JCI146658","article-title":"Long-term corneal recovery by simultaneous delivery of hPSC-derived corneal endothelial precursors and nicotinamide","volume":"132","author":"Li","year":"2022","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.reth.2024.09.001_bib35","doi-asserted-by":"crossref","DOI":"10.2302\/kjm.2023-0001-IR","article-title":"The cornea: an ideal tissue for regenerative medicine","author":"Shimmura","year":"2024","journal-title":"Keio J Med"},{"issue":"11","key":"10.1016\/j.reth.2024.09.001_bib37","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1001\/archophthalmol.2009.263","article-title":"Long-term outcomes of keratolimbal allograft for total limbal stem cell deficiency using combined immunosuppressive agents and correction of ocular surface deficits","volume":"127","author":"Liang","year":"2009","journal-title":"Arch Ophthalmol"},{"issue":"Suppl 1","key":"10.1016\/j.reth.2024.09.001_bib38","doi-asserted-by":"crossref","first-page":"S19","DOI":"10.1097\/ICO.0000000000002566","article-title":"Oral mucosal epithelial transplantation and limbal-rigid contact lens: a therapeutic modality for the treatment of severe ocular surface disorders","volume":"39","author":"Sotozono","year":"2020","journal-title":"Cornea"},{"issue":"7","key":"10.1016\/j.reth.2024.09.001_bib39","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1136\/bjo.2010.188714","article-title":"Long-term results of autologous cultivated oral mucosal epithelial transplantation in the scar phase of severe ocular surface disorders","volume":"95","author":"Nakamura","year":"2011","journal-title":"Br J Ophthalmol"},{"issue":"8","key":"10.1016\/j.reth.2024.09.001_bib40","doi-asserted-by":"crossref","first-page":"1524","DOI":"10.1016\/j.ophtha.2011.01.039","article-title":"Long-term outcome of cultivated oral mucosal epithelial sheet transplantation in treatment of total limbal stem cell deficiency","volume":"118","author":"Satake","year":"2011","journal-title":"Ophthalmology"},{"issue":"4","key":"10.1016\/j.reth.2024.09.001_bib41","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/j.ophtha.2003.07.013","article-title":"Long-term results of allogeneic penetrating limbo-keratoplasty in total limbal stem cell deficiency","volume":"111","author":"Reinhard","year":"2004","journal-title":"Ophthalmology"},{"issue":"3","key":"10.1016\/j.reth.2024.09.001_bib42","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1167\/iovs.04-0575","article-title":"Survival of donor epithelial cells after limbal stem cell transplantation","volume":"46","author":"Djalilian","year":"2005","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"9","key":"10.1016\/j.reth.2024.09.001_bib43","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1007\/s00417-016-3410-2","article-title":"Characterization of the corneal surface in limbal stem cell deficiency and after transplantation of cultured allogeneic limbal epithelial cells","volume":"254","author":"Chen","year":"2016","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"5","key":"10.1016\/j.reth.2024.09.001_bib44","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1136\/bjo.85.5.604","article-title":"The long term outcome of limbal allografts: the search for surviving cells","volume":"85","author":"Henderson","year":"2001","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.reth.2024.09.001_bib45","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.reth.2022.02.004","article-title":"Approach of resource expenditure estimation toward mechanization in the manufacturing of cell-based products","volume":"20","author":"Mizutani","year":"2022","journal-title":"Regen Ther"},{"issue":"1","key":"10.1016\/j.reth.2024.09.001_bib46","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1186\/s13287-016-0432-y","article-title":"Subretinal adipose tissue-derived mesenchymal stem cell implantation in advanced stage retinitis pigmentosa: a phase I clinical safety study","volume":"7","author":"Oner","year":"2016","journal-title":"Stem Cell Res Ther"},{"issue":"1","key":"10.1016\/j.reth.2024.09.001_bib47","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.stemcr.2017.05.016","article-title":"The developmental stage of Adult human stem cell-derived retinal pigment epithelium cells influences transplant efficacy for vision rescue","volume":"9","author":"Davis","year":"2017","journal-title":"Stem Cell Rep"},{"issue":"1","key":"10.1016\/j.reth.2024.09.001_bib48","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/s13287-020-1549-6","article-title":"Management of retinitis pigmentosa by Wharton's jelly derived mesenchymal stem cells: preliminary clinical results","volume":"11","author":"\u00d6zmert","year":"2020","journal-title":"Stem Cell Res Ther"},{"issue":"9817","key":"10.1016\/j.reth.2024.09.001_bib49","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/S0140-6736(12)60028-2","article-title":"Embryonic stem cell trials for macular degeneration: a preliminary report","volume":"379","author":"Schwartz","year":"2012","journal-title":"Lancet"},{"issue":"9967","key":"10.1016\/j.reth.2024.09.001_bib50","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/S0140-6736(14)61376-3","article-title":"Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1\/2 studies","volume":"385","author":"Schwartz","year":"2015","journal-title":"Lancet"},{"issue":"5","key":"10.1016\/j.reth.2024.09.001_bib51","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1016\/j.stemcr.2015.04.005","article-title":"Treatment of macular degeneration using embryonic stem cell-derived retinal pigment epithelium: preliminary results in Asian patients","volume":"4","author":"Song","year":"2015","journal-title":"Stem Cell Rep"},{"issue":"4","key":"10.1016\/j.reth.2024.09.001_bib52","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1038\/nbt.4114","article-title":"Phase 1 clinical study of an embryonic stem cell-derived retinal pigment epithelium patch in age-related macular degeneration","volume":"36","author":"da Cruz","year":"2018","journal-title":"Nat Biotechnol"},{"issue":"3","key":"10.1016\/j.reth.2024.09.001_bib53","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.oret.2019.09.017","article-title":"Surgical method for implantation of a biosynthetic retinal pigment epithelium monolayer for geographic atrophy: experience from a phase 1\/2a study","volume":"4","author":"Kashani","year":"2020","journal-title":"Ophthalmol Retina"},{"issue":"11","key":"10.1016\/j.reth.2024.09.001_bib54","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1056\/NEJMoa1608368","article-title":"Autologous induced stem-cell-derived retinal cells for macular degeneration","volume":"376","author":"Mandai","year":"2017","journal-title":"N\u00a0Engl J Med"},{"issue":"7","key":"10.1016\/j.reth.2024.09.001_bib55","first-page":"2217","article-title":"HLA-matched allogeneic iPS cells-derived RPE transplantation for macular degeneration","volume":"9","author":"Sugita","year":"2020","journal-title":"J\u00a0Clin Med"},{"issue":"12","key":"10.1016\/j.reth.2024.09.001_bib56","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1016\/j.stem.2023.11.004","article-title":"Safety and stable survival of stem-cell-derived retinal organoid for 2 years in patients with retinitis pigmentosa","volume":"30","author":"Hirami","year":"2023","journal-title":"Cell Stem Cell"},{"issue":"1","key":"10.1016\/j.reth.2024.09.001_bib57","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2021.103657","article-title":"A\u00a0Genetic modification that reduces ON-bipolar cells in hESC-derived retinas enhances functional integration after transplantation","volume":"25","author":"Yamasaki","year":"2021","journal-title":"iScience"},{"issue":"5","key":"10.1016\/j.reth.2024.09.001_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2021.108715","article-title":"Generation of functional conjunctival epithelium, including goblet cells, from human iPSCs","volume":"34","author":"Nomi","year":"2021","journal-title":"Cell Rep"},{"issue":"7","key":"10.1016\/j.reth.2024.09.001_bib59","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2023.107016","article-title":"Identification of BST2 as a conjunctival epithelial stem\/progenitor cell marker","volume":"26","author":"Kitao","year":"2023","journal-title":"iScience"},{"issue":"7908","key":"10.1016\/j.reth.2024.09.001_bib60","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1038\/s41586-022-04613-4","article-title":"Generation of 3D lacrimal gland organoids from human pluripotent stem cells","volume":"605","author":"Hayashi","year":"2022","journal-title":"Nature"}],"container-title":["Regenerative Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352320424001627?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352320424001627?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T19:22:23Z","timestamp":1778872943000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352320424001627"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":58,"alternative-id":["S2352320424001627"],"URL":"https:\/\/doi.org\/10.1016\/j.reth.2024.09.001","relation":{},"ISSN":["2352-3204"],"issn-type":[{"value":"2352-3204","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Status and prospects for the development of regenerative therapies for corneal and ocular diseases","name":"articletitle","label":"Article Title"},{"value":"Regenerative Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.reth.2024.09.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier BV on behalf of The Japanese Society for Regenerative Medicine.","name":"copyright","label":"Copyright"}]}}