{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T00:40:43Z","timestamp":1789346443528,"version":"build-2803163510"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T00:00:00Z","timestamp":1731024000000},"content-version":"vor","delay-in-days":160,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004829","name":"Science and Technology Department of Sichuan Province","doi-asserted-by":"publisher","award":["2021JDKP0044"],"award-info":[{"award-number":["2021JDKP0044"]}],"id":[{"id":"10.13039\/501100004829","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013076","name":"National Major Science and Technology Projects of China","doi-asserted-by":"publisher","award":["2017ZX09304023"],"award-info":[{"award-number":["2017ZX09304023"]}],"id":[{"id":"10.13039\/501100013076","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004912","name":"Sichuan University","doi-asserted-by":"publisher","award":["ZYGD18025"],"award-info":[{"award-number":["ZYGD18025"]}],"id":[{"id":"10.13039\/501100004912","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Regenerative Therapy"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1016\/j.reth.2024.11.005","type":"journal-article","created":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T05:23:21Z","timestamp":1732080201000},"page":"1138-1149","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["HUC-MSCs combined with platelet lysate treat diabetic chronic cutaneous ulcers in Bama miniature pig"],"prefix":"10.1016","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3780-3942","authenticated-orcid":false,"given":"Yunyi","family":"Gao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0105-090X","authenticated-orcid":false,"given":"Lihong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5134-9785","authenticated-orcid":false,"given":"Yan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0229-6066","authenticated-orcid":false,"given":"Shiyi","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6634-1241","authenticated-orcid":false,"given":"XingWu","family":"Ran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.reth.2024.11.005_bib1","article-title":"Chinese guideline on prevention and management of diabetic foot (2019 edition)(I)","year":"2019","journal-title":"\u4e2d\u534e\u7cd6\u5c3f\u75c5\u6742\u5fd7"},{"issue":"1","key":"10.1016\/j.reth.2024.11.005_bib2","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s13047-020-00383-2","article-title":"Five year mortality and direct costs of care for people with diabetic foot complications are comparable to cancer","volume":"13","author":"Armstrong","year":"2020","journal-title":"J\u00a0Foot Ankle Res"},{"issue":"9","key":"10.1016\/j.reth.2024.11.005_bib3","doi-asserted-by":"crossref","first-page":"2565","DOI":"10.1002\/term.2153","article-title":"Comparison of in\u00a0vitro-cultivation of human mesenchymal stroma\/stem cells derived from bone marrow and umbilical cord","volume":"11","author":"Hoffmann","year":"2017","journal-title":"J\u00a0Tissue Eng Regen Med"},{"issue":"1","key":"10.1016\/j.reth.2024.11.005_bib4","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1186\/s13287-021-02517-0","article-title":"Exosomes derived from human umbilical cord blood mesenchymal stem cells stimulate regenerative wound healing via transforming growth factor-\u03b2 receptor inhibition","volume":"12","author":"Zhang","year":"2021","journal-title":"Stem Cell Res Ther"},{"issue":"2","key":"10.1016\/j.reth.2024.11.005_bib5","article-title":"Human umbilical cord mesenchymal stem cells transplantation promotes cutaneous wound healing of severe burned rats","volume":"9","author":"Liu","year":"2014","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.reth.2024.11.005_bib6","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1186\/s13287-020-01616-8","article-title":"MSC-derived exosomes attenuate cell death through suppressing AIF nucleus translocation and enhance cutaneous wound healing","volume":"11","author":"Zhao","year":"2020","journal-title":"Stem Cell Res Ther"},{"issue":"5","key":"10.1016\/j.reth.2024.11.005_bib7","doi-asserted-by":"crossref","first-page":"865","DOI":"10.3727\/096368913X676231","article-title":"The human umbilical cord tissue-derived MSC population UCX(\u00ae) promotes early motogenic effects on keratinocytes and fibroblasts and G-CSF-mediated mobilization of BM-MSCs when transplanted in\u00a0vivo","volume":"24","author":"Miranda","year":"2015","journal-title":"Cell Transplant"},{"issue":"19","key":"10.1016\/j.reth.2024.11.005_bib8","doi-asserted-by":"crossref","first-page":"11254","DOI":"10.1111\/jcmm.15692","article-title":"Extracellular vesicle-carried microRNA-27b derived from mesenchymal stem cells accelerates cutaneous wound healing via E3 ubiquitin ligase ITCH","volume":"24","author":"Cheng","year":"2020","journal-title":"J\u00a0Cell Mol Med"},{"key":"10.1016\/j.reth.2024.11.005_bib9","article-title":"Optimising human mesenchymal stem cell numbers for clinical application: a literature review","volume":"2012","author":"Fossett","year":"2012","journal-title":"Stem Cell Int"},{"issue":"9","key":"10.1016\/j.reth.2024.11.005_bib10","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1038\/nm912","article-title":"Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts","volume":"9","author":"Mangi","year":"2003","journal-title":"Nat Med"},{"issue":"6","key":"10.1016\/j.reth.2024.11.005_bib11","doi-asserted-by":"crossref","first-page":"688","DOI":"10.3109\/14653240902974032","article-title":"Analysis of changes in the viability and gene expression profiles of human mesenchymal stromal cells over time","volume":"11","author":"Lee","year":"2009","journal-title":"Cytotherapy"},{"issue":"1","key":"10.1016\/j.reth.2024.11.005_bib12","doi-asserted-by":"crossref","first-page":"22","DOI":"10.2174\/1574888X13666180913123424","article-title":"The clinical trials of mesenchymal stem cell therapy in skin diseases: an update and concise review","volume":"14","author":"Golchin","year":"2019","journal-title":"Curr Stem Cell Res Ther"},{"issue":"5","key":"10.1016\/j.reth.2024.11.005_bib13","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1097\/SAP.0000000000001355","article-title":"Experimental study on effects of adipose-derived stem cell-seeded silk fibroin chitosan film on wound healing of a diabetic rat model","volume":"80","author":"Wu","year":"2018","journal-title":"Ann Plast Surg"},{"key":"10.1016\/j.reth.2024.11.005_bib14","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.biomaterials.2015.10.065","article-title":"Human platelet lysate: replacing fetal bovine serum as a gold standard for human cell propagation?","volume":"76","author":"Burnouf","year":"2016","journal-title":"Biomaterials"},{"issue":"1","key":"10.1016\/j.reth.2024.11.005_bib15","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1186\/s13287-018-0863-8","article-title":"Human platelet lysate in mesenchymal stromal cell expansion according to a GMP grade protocol: a cell factory experience","volume":"9","author":"Becherucci","year":"2018","journal-title":"Stem Cell Res Ther"},{"issue":"17","key":"10.1016\/j.reth.2024.11.005_bib16","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21176284","article-title":"Human platelet lysate supports efficient expansion and stability of wharton's jelly mesenchymal stromal cells via active uptake and release of soluble regenerative factors","volume":"21","author":"Ca\u00f1as-Arboleda","year":"2020","journal-title":"Int J Mol Sci"},{"issue":"10","key":"10.1016\/j.reth.2024.11.005_bib17","doi-asserted-by":"crossref","first-page":"17172","DOI":"10.1002\/jcp.28496","article-title":"Novel therapeutic approaches in utilizing platelet lysate in regenerative medicine: are we ready for clinical use?","volume":"234","author":"Zamani","year":"2019","journal-title":"J\u00a0Cell Physiol"},{"key":"10.1016\/j.reth.2024.11.005_bib18","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.actbio.2016.03.002","article-title":"A\u00a0novel platelet lysate hydrogel for endothelial cell and mesenchymal stem cell-directed neovascularization","volume":"36","author":"Robinson","year":"2016","journal-title":"Acta Biomater"},{"issue":"1","key":"10.1016\/j.reth.2024.11.005_bib19","article-title":"Administration of adipose derived mesenchymal stem cells and platelet lysate in erectile dysfunction: a single center pilot study","volume":"6","author":"Protogerou","year":"2019","journal-title":"Bioengineering (Basel)"},{"issue":"1","key":"10.1016\/j.reth.2024.11.005_bib20","doi-asserted-by":"crossref","first-page":"94","DOI":"10.15283\/ijsc20070","article-title":"The effects of human bone marrow-derived mesenchymal stem cell conditioned media produced with fetal bovine serum or human platelet lysate on skin rejuvenation characteristics","volume":"14","author":"Kim","year":"2021","journal-title":"Int J Stem Cells"},{"issue":"4","key":"10.1016\/j.reth.2024.11.005_bib21","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.tibtech.2007.12.007","article-title":"Novel therapies for scar reduction and regenerative healing of skin wounds","volume":"26","author":"Rhett","year":"2008","journal-title":"Trends Biotechnol"},{"key":"10.1016\/j.reth.2024.11.005_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.110287","article-title":"Current potential therapeutic strategies targeting the TGF-\u03b2\/Smad signaling pathway to attenuate keloid and hypertrophic scar formation","volume":"129","author":"Zhang","year":"2020","journal-title":"Biomed Pharmacother"},{"key":"10.1016\/j.reth.2024.11.005_bib23","doi-asserted-by":"crossref","first-page":"697","DOI":"10.3389\/fcell.2020.00697","article-title":"Mesenchymal stem cells adaptively respond to environmental cues thereby improving granulation tissue formation and wound healing","volume":"8","author":"Jiang","year":"2020","journal-title":"Front Cell Dev Biol"},{"key":"10.1016\/j.reth.2024.11.005_bib24","doi-asserted-by":"crossref","first-page":"28","DOI":"10.3389\/fcell.2017.00028","article-title":"TGF-\u03b21 pretreatment improves the function of mesenchymal stem cells in the wound bed","volume":"5","author":"Ghosh","year":"2017","journal-title":"Front Cell Dev Biol"},{"key":"10.1016\/j.reth.2024.11.005_bib25","doi-asserted-by":"crossref","DOI":"10.1093\/burnst\/tkad058","article-title":"Exosomal miR-4645-5p from hypoxic bone marrow mesenchymal stem cells facilitates diabetic wound healing by restoring keratinocyte autophagy","volume":"12","author":"Shi","year":"2024","journal-title":"Burns Trauma"},{"key":"10.1016\/j.reth.2024.11.005_bib26","doi-asserted-by":"crossref","first-page":"24","DOI":"10.3389\/fphys.2019.00024","article-title":"High glucose suppresses keratinocyte migration through the inhibition of p38 MAPK\/autophagy pathway","volume":"10","author":"Li","year":"2019","journal-title":"Front Physiol"},{"issue":"5","key":"10.1016\/j.reth.2024.11.005_bib27","doi-asserted-by":"crossref","first-page":"785","DOI":"10.2337\/diacare.20.5.785","article-title":"Comparison of fasting and 2-hour glucose and HbA1c levels for diagnosing diabetes. Diagnostic criteria and performance revisited","volume":"20","author":"Engelgau","year":"1997","journal-title":"Diabetes Care"},{"issue":"3","key":"10.1016\/j.reth.2024.11.005_bib28","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1046\/j.1524-475X.1994.20305.x","article-title":"Definitions and guidelines for assessment of wounds and evaluation of healing","volume":"2","author":"Lazarus","year":"1994","journal-title":"Wound Repair Regen"},{"key":"10.1016\/j.reth.2024.11.005_bib29","article-title":"Locally delivered umbilical cord mesenchymal stromal cells reduce chronic inflammation in long-term nonhealing wounds: a randomized study","volume":"2020","author":"Suzdaltseva","year":"2020","journal-title":"Stem Cell Int"},{"issue":"1","key":"10.1016\/j.reth.2024.11.005_bib30","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1186\/s13287-020-01695-7","article-title":"Efficacy and safety of umbilical cord mesenchymal stem cells in treatment of cesarean section skin scars: a randomized clinical trial","volume":"11","author":"Fan","year":"2020","journal-title":"Stem Cell Res Ther"},{"issue":"1","key":"10.1016\/j.reth.2024.11.005_bib31","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1186\/s12917-018-1527-8","article-title":"Allogeneic mesenchymal stem cells improve the wound healing process of sheep skin","volume":"14","author":"Martinello","year":"2018","journal-title":"BMC Vet Res"},{"issue":"11","key":"10.1016\/j.reth.2024.11.005_bib32","first-page":"1267","article-title":"Effect of fibronectin therapy and fibronectin deficiency on wound healing: a study in rats","volume":"27","author":"Nagelschmidt","year":"1987","journal-title":"J\u00a0Trauma"},{"issue":"4","key":"10.1016\/j.reth.2024.11.005_bib33","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1080\/14653240600855905","article-title":"Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement","volume":"8","author":"Dominici","year":"2006","journal-title":"Cytotherapy"},{"issue":"1","key":"10.1016\/j.reth.2024.11.005_bib34","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s12967-017-1145-4","article-title":"Exendin-4 in combination with adipose-derived stem cells promotes angiogenesis and improves diabetic wound healing","volume":"15","author":"Seo","year":"2017","journal-title":"J\u00a0Transl Med"},{"issue":"6599","key":"10.1016\/j.reth.2024.11.005_bib35","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1038\/383441a0","article-title":"The serpin PAI-1 inhibits cell migration by blocking integrin alpha V beta 3 binding to vitronectin","volume":"383","author":"Stefansson","year":"1996","journal-title":"Nature"},{"issue":"7","key":"10.1016\/j.reth.2024.11.005_bib36","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/S1050-1738(03)00142-7","article-title":"Controlling the angiogenic switch: a balance between two distinct TGF-b receptor signaling pathways","volume":"13","author":"Goumans","year":"2003","journal-title":"Trends Cardiovasc Med"},{"issue":"12","key":"10.1016\/j.reth.2024.11.005_bib37","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1007\/s11427-016-0240-4","article-title":"Mesenchymal stem cells-derived exosomal microRNAs contribute to wound inflammation","volume":"59","author":"Ti","year":"2016","journal-title":"Sci China Life Sci"},{"issue":"1","key":"10.1016\/j.reth.2024.11.005_bib38","doi-asserted-by":"crossref","first-page":"169","DOI":"10.7150\/thno.21234","article-title":"Exosomes from human umbilical cord blood accelerate cutaneous wound healing through miR-21-3p-mediated promotion of angiogenesis and fibroblast function","volume":"8","author":"Hu","year":"2018","journal-title":"Theranostics"},{"key":"10.1016\/j.reth.2024.11.005_bib39","article-title":"Mesenchymal stem cells coated by the extracellular matrix promote wound healing in diabetic rats","volume":"2019","author":"Wang","year":"2019","journal-title":"Stem Cell Int"},{"issue":"1","key":"10.1016\/j.reth.2024.11.005_bib40","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/wrr.12098","article-title":"Altered TGF-\u03b2 signaling in fetal fibroblasts: what is known about the underlying mechanisms?","volume":"22","author":"Walraven","year":"2014","journal-title":"Wound Repair Regen"},{"issue":"1","key":"10.1016\/j.reth.2024.11.005_bib41","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1186\/s13287-020-01723-6","article-title":"Human bone marrow mesenchymal stem cell-derived exosomes stimulate cutaneous wound healing mediates through TGF-\u03b2\/Smad signaling pathway","volume":"11","author":"Jiang","year":"2020","journal-title":"Stem Cell Res Ther"},{"issue":"6","key":"10.1016\/j.reth.2024.11.005_bib42","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1007\/s00418-023-02221-5","article-title":"Heterogeneous response to TGF-\u03b21\/3 isoforms in fibroblasts of different origins: implications for wound healing and tumorigenesis","volume":"160","author":"Urban","year":"2023","journal-title":"Histochem Cell Biol"},{"issue":"9","key":"10.1016\/j.reth.2024.11.005_bib43","doi-asserted-by":"crossref","DOI":"10.3390\/cells7090142","article-title":"Platelet-rich plasma prevents in\u00a0vitro transforming growth factor-\u03b21-induced fibroblast to myofibroblast transition: involvement of vascular endothelial growth factor (VEGF)-A\/VEGF receptor-1-mediated signaling (\u2020)","volume":"7","author":"Chellini","year":"2018","journal-title":"Cells"},{"issue":"10","key":"10.1016\/j.reth.2024.11.005_bib44","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.5966\/sctm.2015-0367","article-title":"Umbilical cord-derived mesenchymal stem cell-derived exosomal MicroRNAs suppress myofibroblast differentiation by inhibiting the transforming growth factor-\u03b2\/SMAD2 pathway during wound healing","volume":"5","author":"Fang","year":"2016","journal-title":"Stem Cells Transl Med"},{"issue":"7","key":"10.1016\/j.reth.2024.11.005_bib45","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0037512","article-title":"Bone marrow mesenchymal stromal cells stimulate skeletal myoblast proliferation through the paracrine release of VEGF","volume":"7","author":"Sassoli","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.reth.2024.11.005_bib46","article-title":"Synergistic effects of human platelet-rich plasma combined with adipose-derived stem cells on healing in a mouse pressure injury model","volume":"2019","author":"Liu","year":"2019","journal-title":"Stem Cell Int"},{"issue":"3","key":"10.1016\/j.reth.2024.11.005_bib47","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1016\/j.ijrobp.2010.05.002","article-title":"Development of a porcine delayed wound-healing model and its use in testing a novel cell-based therapy","volume":"78","author":"Hadad","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"5","key":"10.1016\/j.reth.2024.11.005_bib48","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1139\/bcb-2016-0224","article-title":"Can mesenchymal stem cells pretreated with platelet-rich plasma modulate tissue remodeling in a rat with burned skin?","volume":"95","author":"Hosni","year":"2017","journal-title":"Biochem Cell Biol"},{"issue":"2","key":"10.1016\/j.reth.2024.11.005_bib49","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1111\/exd.14042","article-title":"Platelet-rich plasma improves the therapeutic efficacy of mesenchymal stem cells by enhancing their secretion of angiogenic factors in a combined radiation and wound injury model","volume":"29","author":"Myung","year":"2020","journal-title":"Exp Dermatol"},{"issue":"1","key":"10.1016\/j.reth.2024.11.005_bib50","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1111\/iwj.12551","article-title":"Mesenchymal stem cell-conditioned medium accelerates wound healing with fewer scars","volume":"14","author":"Li","year":"2017","journal-title":"Int Wound J"},{"issue":"7","key":"10.1016\/j.reth.2024.11.005_bib51","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1016\/j.jcyt.2015.03.690","article-title":"Paracrine action of mesenchymal stromal cells delivered by microspheres contributes to cutaneous wound healing and prevents scar formation in mice","volume":"17","author":"Huang","year":"2015","journal-title":"Cytotherapy"},{"issue":"1","key":"10.1016\/j.reth.2024.11.005_bib52","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1186\/s13287-019-1229-6","article-title":"Silk fibroin scaffolds seeded with Wharton's jelly mesenchymal stem cells enhance re-epithelialization and reduce formation of scar tissue after cutaneous wound healing","volume":"10","author":"Mill\u00e1n-Rivero","year":"2019","journal-title":"Stem Cell Res Ther"},{"issue":"1","key":"10.1016\/j.reth.2024.11.005_bib53","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1177\/1534734614568373","article-title":"Mesenchymal stem cells suppress fibroblast proliferation and reduce skin fibrosis through a TGF-\u03b23-dependent activation","volume":"14","author":"Wu","year":"2015","journal-title":"Int J Low Extrem Wounds"},{"issue":"1","key":"10.1016\/j.reth.2024.11.005_bib54","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1093\/jbcr\/irab079","article-title":"Autologous platelet-rich plasma repairs burn wound and reduces burn pain in rats","volume":"43","author":"Ren","year":"2022","journal-title":"J\u00a0Burn Care Res"},{"key":"10.1016\/j.reth.2024.11.005_bib55","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.actbio.2021.01.046","article-title":"A\u00a0composite hydrogel with co-delivery of antimicrobial peptides and platelet-rich plasma to enhance healing of infected wounds in diabetes","volume":"124","author":"Wei","year":"2021","journal-title":"Acta Biomater"},{"key":"10.1016\/j.reth.2024.11.005_bib56","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1016\/j.ijbiomac.2020.11.014","article-title":"Development of nanosilver doped carboxymethyl chitosan-polyamideamine alginate composite dressing for wound treatment","volume":"166","author":"Zhou","year":"2021","journal-title":"Int J Biol Macromol"},{"issue":"1","key":"10.1016\/j.reth.2024.11.005_bib57","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1186\/s13287-020-01756-x","article-title":"Melatonin-stimulated MSC-derived exosomes improve diabetic wound healing through regulating macrophage M1 and M2 polarization by targeting the PTEN\/AKT pathway","volume":"11","author":"Liu","year":"2020","journal-title":"Stem Cell Res Ther"},{"key":"10.1016\/j.reth.2024.11.005_bib58","doi-asserted-by":"crossref","first-page":"203","DOI":"10.3389\/fbioe.2018.00203","article-title":"Platelet lysate activates human subcutaneous adipose tissue cells by promoting cell proliferation and their paracrine activity toward epidermal keratinocytes","volume":"6","author":"Romaldini","year":"2018","journal-title":"Front Bioeng Biotechnol"}],"container-title":["Regenerative Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352320424001974?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352320424001974?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T19:22:00Z","timestamp":1778872920000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352320424001974"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":58,"alternative-id":["S2352320424001974"],"URL":"https:\/\/doi.org\/10.1016\/j.reth.2024.11.005","relation":{},"ISSN":["2352-3204"],"issn-type":[{"value":"2352-3204","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"HUC-MSCs combined with platelet lysate treat diabetic chronic cutaneous ulcers in Bama miniature pig","name":"articletitle","label":"Article Title"},{"value":"Regenerative Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.reth.2024.11.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier BV on behalf of The Japanese Society for Regenerative Medicine.","name":"copyright","label":"Copyright"}]}}