{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T08:28:50Z","timestamp":1789201730171,"version":"build-2803163510"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,29]],"date-time":"2025-03-29T00:00:00Z","timestamp":1743206400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Regenerative Therapy"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.reth.2025.03.020","type":"journal-article","created":{"date-parts":[[2025,4,12]],"date-time":"2025-04-12T03:06:41Z","timestamp":1744427201000},"page":"397-403","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Operator stress factors and cell contamination risks in cell processing facilities: An online survey-based analysis"],"prefix":"10.1016","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0349-0362","authenticated-orcid":false,"given":"Yoshimi","family":"Sugahara","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuru","family":"Mizuno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0771-6514","authenticated-orcid":false,"given":"Noe","family":"Miyashita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6952-895X","authenticated-orcid":false,"given":"Hisako","family":"Katano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6331-722X","authenticated-orcid":false,"given":"Ichiro","family":"Sekiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.reth.2025.03.020_bib1","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.reth.2022.10.004","article-title":"Stress and motivation of cell processing operators: a pilot study of an online questionnaire survey","volume":"21","author":"Mizuno","year":"2022","journal-title":"Regen Ther"},{"key":"10.1016\/j.reth.2025.03.020_bib2","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.reth.2024.01.001","article-title":"Operator-derived particles and falling bacteria in biosafety cabinets","volume":"25","author":"Mizuno","year":"2024","journal-title":"Regen Ther"},{"key":"10.1016\/j.reth.2025.03.020_bib3","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.reth.2022.12.003","article-title":"Cross-contamination risk and decontamination during changeover after cell-product processing","volume":"22","author":"Mizuno","year":"2023","journal-title":"Regen Ther"},{"key":"10.1016\/j.reth.2025.03.020_bib4","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0236600","article-title":"The environmental risk assessment of cell-processing facilities for cell therapy in a Japanese academic institution","volume":"15","author":"Mizuno","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.reth.2025.03.020_bib5","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.reth.2024.11.020","article-title":"Cleaning methods for biosafety cabinet to eliminate residual mycoplasmas, viruses, and endotoxins after changeover","volume":"28","author":"Mizuno","year":"2025","journal-title":"Regen Ther"},{"key":"10.1016\/j.reth.2025.03.020_bib6","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1007\/s00464-002-9224-9","article-title":"The effect of stress-inducing conditions on the performance of a laparoscopic task","volume":"17","author":"Moorthy","year":"2003","journal-title":"Surg Endosc"},{"key":"10.1016\/j.reth.2025.03.020_bib7","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1097\/00005110-200602000-00007","article-title":"The impact of multiple care giving roles on fatigue, stress, and work performance among hospital staff nurses","volume":"36","author":"Scott","year":"2006","journal-title":"J Nurs Adm"},{"key":"10.1016\/j.reth.2025.03.020_bib8","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.reth.2015.05.001","article-title":"A study on ensuring the quality and safety of pharmaceuticals and medical devices derived from the processing of allogeneic human somatic stem cells","volume":"2","author":"Hayakawa","year":"2015","journal-title":"Regen Ther"},{"key":"10.1016\/j.reth.2025.03.020_bib9","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.reth.2015.06.004","article-title":"A study on ensuring the quality and safety of pharmaceuticals and medical devices derived from processing of allogeneic human induced pluripotent stem(-like) cells","volume":"2","author":"Hayakawa","year":"2015","journal-title":"Regen Ther"},{"key":"10.1016\/j.reth.2025.03.020_bib10","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.reth.2015.06.002","article-title":"A study on ensuring the quality and safety of pharmaceuticals and medical devices derived from processing of autologous human induced pluripotent stem(-like) cells","volume":"2","author":"Hayakawa","year":"2015","journal-title":"Regen Ther"},{"key":"10.1016\/j.reth.2025.03.020_bib11","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.reth.2015.06.001","article-title":"A study on ensuring the quality and safety of pharmaceuticals and medical devices derived from the processing of human embryonic stem cells","volume":"2","author":"Hayakawa","year":"2015","journal-title":"Regen Ther"},{"key":"10.1016\/j.reth.2025.03.020_bib12","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.reth.2015.05.002","article-title":"A study on ensuring the quality and safety of pharmaceuticals and medical devices derived from the processing of autologous human somatic stem cells","volume":"2","author":"Hayakawa","year":"2015","journal-title":"Regen Ther"},{"key":"10.1016\/j.reth.2025.03.020_bib13","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.reth.2016.06.004","article-title":"Experience of contamination during autologous cell manufacturing in cell processing facility under the Japanese Medical Practitioners Act and the Medical Care Act","volume":"5","author":"Mizutani","year":"2016","journal-title":"Regen Ther"},{"key":"10.1016\/j.reth.2025.03.020_bib14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.reth.2014.12.002","article-title":"How to prevent contamination with Candida albicans during the fabrication of transplantable oral mucosal epithelial cell sheets","volume":"1","author":"Takagi","year":"2015","journal-title":"Regen Ther"},{"key":"10.1016\/j.reth.2025.03.020_bib15","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.3109\/14653249.2012.698728","article-title":"Real-time monitoring of non-viable airborne particles correlates with airborne colonies and represents an acceptable surrogate for daily assessment of cell-processing cleanroom performance","volume":"14","author":"Raval","year":"2012","journal-title":"Cytotherapy"},{"key":"10.1016\/j.reth.2025.03.020_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejps.2019.104973","article-title":"Culture independent approach reveals domination of human-oriented microbes in a pharmaceutical manufacturing facility","volume":"137","author":"Kawai","year":"2019","journal-title":"Eur J Pharm Sci"},{"key":"10.1016\/j.reth.2025.03.020_bib17","doi-asserted-by":"crossref","first-page":"A96","DOI":"10.1016\/j.ajic.2019.01.014","article-title":"Best practices for disinfection of noncritical environmental surfaces and equipment in health care facilities: a bundle approach","volume":"47S","author":"Rutala","year":"2019","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.reth.2025.03.020_bib18","doi-asserted-by":"crossref","first-page":"e159","DOI":"10.1016\/j.ajic.2012.04.281","article-title":"Maintenance of environmental services cleaning and disinfection in the ICU after a performance improvement project","volume":"40","author":"Fitzgerald","year":"2012","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.reth.2025.03.020_bib19","doi-asserted-by":"crossref","first-page":"392","DOI":"10.5731\/pdajpst.2011.00765","article-title":"A review of cleanroom microflora: types, trends, and patterns","volume":"65","author":"Sandle","year":"2011","journal-title":"PDA J Pharm Sci Technol"},{"key":"10.1016\/j.reth.2025.03.020_bib20","first-page":"235","article-title":"Proposal for a new categorization of aseptic processing facilities based on risk assessment scores","volume":"62","author":"Katayama","year":"2008","journal-title":"PDA J Pharm Sci Technol"},{"key":"10.1016\/j.reth.2025.03.020_bib21","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.reth.2024.07.002","article-title":"Evaluation of cleaning methods for change-over after the processing of cell products to avoid cross-contamination risk","volume":"26","author":"Mizuno","year":"2024","journal-title":"Regen Ther"},{"key":"10.1016\/j.reth.2025.03.020_bib22","first-page":"425","article-title":"Flow and performance of an air-curtain biological safety cabinet","volume":"53","author":"Huang","year":"2009","journal-title":"Ann Occup Hyg"},{"key":"10.1016\/j.reth.2025.03.020_bib23","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1631\/jzus.2007.B0666","article-title":"Characterization of predominant bacteria isolates from clean rooms in a pharmaceutical production unit","volume":"8","author":"Wu","year":"2007","journal-title":"J Zhejiang Univ - Sci B"},{"key":"10.1016\/j.reth.2025.03.020_bib24","author":"Zhang"},{"key":"10.1016\/j.reth.2025.03.020_bib25","doi-asserted-by":"crossref","DOI":"10.3389\/frma.2024.1331589","article-title":"Paradigm shifts: exploring AI's influence on qualitative inquiry and analysis","volume":"9","author":"Williams","year":"2024","journal-title":"Front Res Metr Anal"},{"key":"10.1016\/j.reth.2025.03.020_bib26","first-page":"1968","article-title":"\u0397ow to use artificial intelligence (AI) as a resource, methodological and analysis tool in qualitative research?","volume":"28","author":"Christou","year":"2023","journal-title":"Qual Rep"},{"key":"10.1016\/j.reth.2025.03.020_bib27","doi-asserted-by":"crossref","first-page":"e231","DOI":"10.2196\/jmir.9702","article-title":"Augmenting qualitative text analysis with natural language processing: methodological study","volume":"20","author":"Guetterman","year":"2018","journal-title":"J Med Internet Res"}],"container-title":["Regenerative Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352320425000744?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352320425000744?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T04:27:38Z","timestamp":1763699258000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352320425000744"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":27,"alternative-id":["S2352320425000744"],"URL":"https:\/\/doi.org\/10.1016\/j.reth.2025.03.020","relation":{},"ISSN":["2352-3204"],"issn-type":[{"value":"2352-3204","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Operator stress factors and cell contamination risks in cell processing facilities: An online survey-based analysis","name":"articletitle","label":"Article Title"},{"value":"Regenerative Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.reth.2025.03.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier BV on behalf of The Japanese Society for Regenerative Medicine.","name":"copyright","label":"Copyright"}]}}