{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T03:47:55Z","timestamp":1791863275250,"version":"4.3.4"},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T00:00:00Z","timestamp":1784160000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004206","name":"Osaka University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004206","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Regenerative Therapy"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.reth.2026.101161","type":"journal-article","created":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T09:32:34Z","timestamp":1784799154000},"page":"101161","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Impact of secretome containing extracellular vesicles from human induced pluripotent stem cell-derived cardiomyocytes"],"prefix":"10.1016","volume":"33","author":[{"given":"Yuki","family":"Saito","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-8711-8377","authenticated-orcid":false,"given":"Kazuaki","family":"Takemura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0024-4067","authenticated-orcid":false,"given":"Junya","family":"Aoyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9391-268X","authenticated-orcid":false,"given":"Sawako","family":"Hibino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5947-5471","authenticated-orcid":false,"given":"Kouichi","family":"Hasegawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiki","family":"Sawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.reth.2026.101161_bib1","article-title":"Global epidemiology of ischemic heart disease: results from the global burden of disease study","volume":"12","author":"Khan","year":"2020","journal-title":"Cureus"},{"key":"10.1016\/j.reth.2026.101161_bib2","doi-asserted-by":"crossref","first-page":"2981","DOI":"10.1161\/01.CIR.101.25.2981","article-title":"Left ventricular remodeling after myocardial infarction: pathophysiology and therapy","volume":"101","author":"Sutton","year":"2000","journal-title":"Circulation"},{"key":"10.1016\/j.reth.2026.101161_bib3","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1161\/CIRCRESAHA.113.300219","article-title":"Cell therapy for heart failure: a comprehensive overview of experimental and clinical studies, current challenges, and future directions","volume":"113","author":"Sanganalmath","year":"2013","journal-title":"Circ Res"},{"key":"10.1016\/j.reth.2026.101161_bib4","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1093\/eurheartj\/ehw113","article-title":"Position paper of the european society of cardiology working group cellular biology of the heart: cell-based therapies for myocardial repair and regeneration in ischemic heart disease and heart failure","volume":"37","author":"Madonna","year":"2016","journal-title":"Eur Heart J"},{"key":"10.1016\/j.reth.2026.101161_bib5","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1161\/CIRCULATIONAHA.117.029343","article-title":"Cardiomyocyte regeneration: a consensus statement","volume":"136","author":"Eschenhagen","year":"2017","journal-title":"Circulation"},{"key":"10.1016\/j.reth.2026.101161_bib6","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1161\/CIRCRESAHA.109.208991","article-title":"Assessment and optimization of cell engraftment after transplantation into the heart","volume":"106","author":"Terrovitis","year":"2010","journal-title":"Circ Res"},{"key":"10.1016\/j.reth.2026.101161_bib7","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1007\/s12265-020-10035-2","article-title":"Requirements for proper immunosuppressive regimens to limit translational failure of cardiac cell therapy in preclinical large animal models","volume":"14","author":"Demkes","year":"2021","journal-title":"J Cardiovasc Transl Res"},{"key":"10.1016\/j.reth.2026.101161_bib8","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1038\/nature13233","article-title":"Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts","volume":"510","author":"Chong","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.reth.2026.101161_bib9","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1161\/CIRCRESAHA.108.176826","article-title":"Paracrine mechanisms in adult stem cell signaling and therapy","volume":"103","author":"Gnecchi","year":"2008","journal-title":"Circ Res"},{"key":"10.1016\/j.reth.2026.101161_bib10","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1161\/CIRCRESAHA.114.300639","article-title":"Exosomes and cardiac repair after myocardial infarction","volume":"114","author":"Sahoo","year":"2014","journal-title":"Circ Res"},{"key":"10.1016\/j.reth.2026.101161_bib11","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.healun.2023.08.011","article-title":"Pleiotropic effects of extracellular vesicles from induced pluripotent stem cell-derived cardiomyocytes on ischemic cardiomyopathy: a preclinical study","volume":"43","author":"Tominaga","year":"2024","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.reth.2026.101161_bib12","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1186\/s13287-024-03690-8","article-title":"Pre-clinical evaluation of the efficacy and safety of human induced pluripotent stem cell-derived cardiomyocyte patch","volume":"15","author":"Miyagawa","year":"2024","journal-title":"Stem Cell Res Ther"},{"key":"10.1016\/j.reth.2026.101161_bib13","doi-asserted-by":"crossref","first-page":"49","DOI":"10.3389\/fcell.2020.00049","article-title":"Secretome analysis performed during in vitro cardiac differentiation: discovering the cardiac microenvironment","volume":"8","author":"Robert","year":"2020","journal-title":"Front Cell Dev Biol"},{"key":"10.1016\/j.reth.2026.101161_bib14","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1021\/acsomega.4c06371","article-title":"Proteomic approach using DIA-MS identifies morphogenesis-associated proteins during cardiac differentiation of human iPS cells","volume":"10","author":"Urasawa","year":"2025","journal-title":"ACS Omega"},{"key":"10.1016\/j.reth.2026.101161_bib15","doi-asserted-by":"crossref","first-page":"2622","DOI":"10.3390\/cells10102622","article-title":"Proteomic analysis of exosomes during cardiogenic differentiation of human pluripotent stem cells","volume":"10","author":"Ashok","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.reth.2026.101161_bib16","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2022.950829","article-title":"Case report: transplantation of human induced pluripotent stem cell-derived cardiomyocyte patches for ischemic cardiomyopathy","volume":"9","author":"Miyagawa","year":"2022","journal-title":"Front Cardiovasc Med"},{"key":"10.1016\/j.reth.2026.101161_bib17","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1038\/nmeth.1591","article-title":"A more efficient method to generate integration-free human iPS cells","volume":"8","author":"Okita","year":"2011","journal-title":"Nat Methods"},{"key":"10.1016\/j.reth.2026.101161_bib18","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1002\/stem.1293","article-title":"An efficient nonviral method to generate integration-free human-induced pluripotent stem cells from cord blood and peripheral blood cells","volume":"31","author":"Okita","year":"2013","journal-title":"Stem Cell"},{"key":"10.1016\/j.reth.2026.101161_bib19","doi-asserted-by":"crossref","first-page":"3594","DOI":"10.1038\/srep03594","article-title":"A novel efficient feeder-free culture system for the derivation of human induced pluripotent stem cells","volume":"4","author":"Nakagawa","year":"2014","journal-title":"Sci Rep"},{"key":"10.1016\/j.reth.2026.101161_bib20","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1038\/s41598-018-38325-5","article-title":"Tumorigenicity assay essential for facilitating safety studies of hiPSC-derived cardiomyocytes for clinical application","volume":"9","author":"Ito","year":"2019","journal-title":"Sci Rep"},{"key":"10.1016\/j.reth.2026.101161_bib21","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nmeth.3317","article-title":"HISAT: a fast spliced aligner with low memory requirements","volume":"12","author":"Kim","year":"2015","journal-title":"Nat Methods"},{"key":"10.1016\/j.reth.2026.101161_bib22","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1093\/bioinformatics\/btt656","article-title":"featureCounts: an efficient general purpose program for assigning sequence reads to genomic features","volume":"30","author":"Liao","year":"2014","journal-title":"Bioinformatics"},{"key":"10.1016\/j.reth.2026.101161_bib23","doi-asserted-by":"crossref","first-page":"e47","DOI":"10.1093\/nar\/gkv007","article-title":"Limma powers differential expression analyses for RNA-sequencing and microarray studies","volume":"43","author":"Ritchie","year":"2015","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.reth.2026.101161_bib24","doi-asserted-by":"crossref","first-page":"D155","DOI":"10.1093\/nar\/gky1141","article-title":"miRBase: from microRNA sequences to function","volume":"47","author":"Kozomara","year":"2019","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.reth.2026.101161_bib25","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nmeth.1923","article-title":"Fast gapped-read alignment with Bowtie 2","volume":"9","author":"Langmead","year":"2012","journal-title":"Nat Methods"},{"key":"10.1016\/j.reth.2026.101161_bib26","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1093\/bioinformatics\/btp352","article-title":"The sequence alignment\/map format and SAMtools","volume":"25","author":"Li","year":"2009","journal-title":"Bioinformatics"},{"key":"10.1016\/j.reth.2026.101161_bib27","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1021\/acs.jproteome.2c00023","article-title":"Single-shot 10K proteome approach: over 10,000 protein identifications by data-independent acquisition-based single-shot proteomics with ion mobility spectrometry","volume":"21","author":"Kawashima","year":"2022","journal-title":"J Proteome Res"},{"key":"10.1016\/j.reth.2026.101161_bib28","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1038\/s41592-019-0638-x","article-title":"DIA-NN: neural networks and interference correction enable deep proteome coverage in high throughput","volume":"17","author":"Demichev","year":"2020","journal-title":"Nat Methods"},{"key":"10.1016\/j.reth.2026.101161_bib29","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1038\/nmeth.3901","article-title":"The Perseus computational platform for comprehensive analysis of (prote)omics data","volume":"13","author":"Tyanova","year":"2016","journal-title":"Nat Methods"},{"key":"10.1016\/j.reth.2026.101161_bib30","doi-asserted-by":"crossref","first-page":"D1107","DOI":"10.1093\/nar\/gkw1080","article-title":"jPOSTrepo: an international standard data repository for proteomes","volume":"45","author":"Okuda","year":"2017","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.reth.2026.101161_bib31","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/nprot.2007.30","article-title":"In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro","volume":"2","author":"Liang","year":"2007","journal-title":"Nat Protoc"},{"key":"10.1016\/j.reth.2026.101161_bib32","doi-asserted-by":"crossref","DOI":"10.3791\/51312-v","article-title":"Endothelial cell tube formation assay for the in vitro study of angiogenesis","author":"DeCicco-Skinner","year":"2014","journal-title":"J Vis Exp"},{"key":"10.1016\/j.reth.2026.101161_bib33","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-67289-8","article-title":"Angiogenesis analyzer for ImageJ - a comparative morphometric analysis of \u201cEndothelial Tube Formation Assay\u201d and \u201cFibrin Bead Assay.\u201d","volume":"10","author":"Carpentier","year":"2020","journal-title":"Sci Rep"},{"key":"10.1016\/j.reth.2026.101161_bib34","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1186\/s40104-020-00500-y","article-title":"MiR-214-3p promotes proliferation and inhibits estradiol synthesis in porcine granulosa cells","volume":"11","author":"Shi","year":"2020","journal-title":"J Anim Sci Biotechnol"},{"key":"10.1016\/j.reth.2026.101161_bib35","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1186\/s40824-023-00410-w","article-title":"Exosomes derived from mir-214-3p overexpressing mesenchymal stem cells promote myocardial repair","volume":"27","author":"Zhu","year":"2023","journal-title":"Biomater Res"},{"key":"10.1016\/j.reth.2026.101161_bib36","doi-asserted-by":"crossref","first-page":"29209","DOI":"10.18632\/oncotarget.4976","article-title":"H19 non coding RNA-derived miR-675 enhances tumorigenesis and metastasis of breast cancer cells by downregulating c-Cbl and Cbl-b","volume":"6","author":"Vennin","year":"2015","journal-title":"Oncotarget"},{"key":"10.1016\/j.reth.2026.101161_bib37","article-title":"LncRNAs in cardiomyocyte maturation: new window for cardiac regenerative medicine","volume":"7","author":"Kay","year":"2021","journal-title":"Noncod RNA"},{"key":"10.1016\/j.reth.2026.101161_bib38","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.yjmcc.2016.03.015","article-title":"Cardiac-specific miRNA in cardiogenesis, heart function, and cardiac pathology (with focus on myocardial infarction)","volume":"94","author":"Frangogiannis","year":"2016","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.reth.2026.101161_bib39","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1038\/nature08195","article-title":"miR-145 and miR-143 regulate smooth muscle cell fate and plasticity","volume":"460","author":"Cordes","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.reth.2026.101161_bib40","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1177\/1535370214546268","article-title":"miR-1, miR-133a\/b, and miR-208a in human fetal hearts correlate to the apoptotic and proliferation markers","volume":"240","author":"Bo\u0161tjan\u010di\u010d","year":"2015","journal-title":"Exp Biol Med (Maywood)"},{"key":"10.1016\/j.reth.2026.101161_bib41","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1089\/dna.2012.1787","article-title":"The emerging role of miR-208a in the heart","volume":"32","author":"Oliveira-Carvalho","year":"2013","journal-title":"DNA Cell Biol"},{"key":"10.1016\/j.reth.2026.101161_bib42","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0027417","article-title":"Distinct roles of microRNA-1 and -499 in ventricular specification and functional maturation of human embryonic stem cell-derived cardiomyocytes","volume":"6","author":"Fu","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.reth.2026.101161_bib43","doi-asserted-by":"crossref","DOI":"10.3892\/mmr.2022.12692","article-title":"Role and mechanism of the lncRNA SNHG1\/miR-450b-5p\/IGF1 axis in the regulation of myocardial ischemia reperfusion injury","volume":"25","author":"Zhan","year":"2022","journal-title":"Mol Med Rep"},{"key":"10.1016\/j.reth.2026.101161_bib44","doi-asserted-by":"crossref","first-page":"6975","DOI":"10.1038\/s41388-020-01514-6","article-title":"MCU-dependent negative sorting of miR-4488 to extracellular vesicles enhances angiogenesis and promotes breast cancer metastatic colonization","volume":"39","author":"Zheng","year":"2020","journal-title":"Oncogene"},{"key":"10.1016\/j.reth.2026.101161_bib45","doi-asserted-by":"crossref","first-page":"9693","DOI":"10.1080\/21655979.2021.1987068","article-title":"Exosomal miR-4488 and miR-1273g-5p inhibit the epithelial-mesenchymal transition of transforming growth factor \u03b22-mediated retinal pigment epithelial cells by targeting ATP-binding cassette A4","volume":"12","author":"Dong","year":"2021","journal-title":"Bioengineered"},{"key":"10.1016\/j.reth.2026.101161_bib46","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.ymthe.2016.12.022","article-title":"Human pericardial fluid contains exosomes enriched with cardiovascular-expressed microRNAs and promotes therapeutic angiogenesis","volume":"25","author":"Beltrami","year":"2017","journal-title":"Mol Ther"},{"key":"10.1016\/j.reth.2026.101161_bib47","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.7150\/jca.29536","article-title":"Hsa-let-7e-5p inhibits the proliferation and metastasis of head and neck squamous cell carcinoma cells by targeting chemokine receptor 7","volume":"10","author":"Wang","year":"2019","journal-title":"J Cancer"},{"key":"10.1016\/j.reth.2026.101161_bib48","article-title":"Biological functions of Let-7e-5p in promoting the differentiation of MC3T3-E1 cells","volume":"9","author":"Wang","year":"2021","journal-title":"Front Cell Dev Biol"},{"key":"10.1016\/j.reth.2026.101161_bib49","doi-asserted-by":"crossref","first-page":"6163","DOI":"10.7150\/thno.28021","article-title":"Hypoxia-elicited mesenchymal stem cell-derived exosomes facilitates cardiac repair through miR-125b-mediated prevention of cell death in myocardial infarction","volume":"8","author":"Zhu","year":"2018","journal-title":"Theranostics"},{"key":"10.1016\/j.reth.2026.101161_bib50","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.21037\/atm-22-6109","article-title":"M2 macrophage-derived exosomal miR-145-5p protects against the hypoxia\/reoxygenation-induced pyroptosis of cardiomyocytes by inhibiting TLR4 expression","volume":"10","author":"Wei","year":"2022","journal-title":"Ann Transl Med"},{"key":"10.1016\/j.reth.2026.101161_bib51","first-page":"6895","article-title":"MicroRNA-542-3p suppresses tumor cell proliferation via targeting Smad2 inhuman osteosarcoma","volume":"15","author":"Wu","year":"2018","journal-title":"Oncol Lett"},{"key":"10.1016\/j.reth.2026.101161_bib52","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/s13046-017-0532-2","article-title":"Overexpression of miR-584-5p inhibits proliferation and induces apoptosis by targeting WW domain-containing E3 ubiquitin protein ligase 1 in gastric cancer","volume":"36","author":"Li","year":"2017","journal-title":"J Exp Clin Cancer Res"},{"key":"10.1016\/j.reth.2026.101161_bib53","doi-asserted-by":"crossref","first-page":"825","DOI":"10.4149\/neo_2020_190730N687","article-title":"MiR-193a-5p suppresses cell proliferation and induces cell apoptosis by regulating HOXA7 in human ovarian cancer","volume":"67","author":"Wang","year":"2020","journal-title":"Neoplasma"},{"key":"10.1016\/j.reth.2026.101161_bib54","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-025-32320-3","article-title":"miR-193a-5p-mediated inhibition of the METTL1\/COX-2 axis is critical for astragalin-induced apoptosis in cervical cancer","volume":"16","author":"Lee","year":"2025","journal-title":"Sci Rep"},{"key":"10.1016\/j.reth.2026.101161_bib55","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.bbrc.2011.10.117","article-title":"miR-125b suppresses the proliferation and migration of osteosarcoma cells through down-regulation of STAT3","volume":"416","author":"Liu","year":"2011","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.reth.2026.101161_bib56","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1038\/nature10144","article-title":"Molecular mechanisms and clinical applications of angiogenesis","volume":"473","author":"Carmeliet","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.reth.2026.101161_bib57","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1089\/scd.2014.0533","article-title":"Immaturity of human stem-cell-derived cardiomyocytes in culture: fatal flaw or soluble problem?","volume":"24","author":"Veerman","year":"2015","journal-title":"Stem Cell Dev"},{"key":"10.1016\/j.reth.2026.101161_bib58","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1083\/jcb.201211138","article-title":"Extracellular vesicles: exosomes, microvesicles, and friends","volume":"200","author":"Raposo","year":"2013","journal-title":"J Cell Biol"},{"key":"10.1016\/j.reth.2026.101161_bib59","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1002\/jcsm.12227","article-title":"Circulating myomiRs: a new class of biomarkers to monitor skeletal muscle in physiology and medicine","volume":"9","author":"Siracusa","year":"2017","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"10.1016\/j.reth.2026.101161_bib60","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1038\/nm1075","article-title":"Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1","volume":"10","author":"Ceradini","year":"2004","journal-title":"Nat Med"},{"key":"10.1016\/j.reth.2026.101161_bib61","doi-asserted-by":"crossref","first-page":"239","DOI":"10.21037\/tp.2018.01.01","article-title":"Role of stromal cell derived factor-1 in myocardial healing\u2014novel insights from comparative studies in the fetal and postnatal myocardium","volume":"7","author":"Hofmann","year":"2018","journal-title":"Transl Pediatr"},{"key":"10.1016\/j.reth.2026.101161_bib62","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1161\/01.RES.0000194330.66545.f5","article-title":"Restoration of cardiac progenitor cells after myocardial infarction by self-proliferation and selective homing of bone marrow-derived stem cells","volume":"97","author":"Mouquet","year":"2005","journal-title":"Circ Res"}],"container-title":["Regenerative Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352320426001021?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352320426001021?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T03:33:02Z","timestamp":1791862382000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352320426001021"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":62,"alternative-id":["S2352320426001021"],"URL":"https:\/\/doi.org\/10.1016\/j.reth.2026.101161","relation":{},"ISSN":["2352-3204"],"issn-type":[{"value":"2352-3204","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of secretome containing extracellular vesicles from human induced pluripotent stem cell-derived cardiomyocytes","name":"articletitle","label":"Article Title"},{"value":"Regenerative Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.reth.2026.101161","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier BV on behalf of The Japanese Society for Regenerative Medicine.","name":"copyright","label":"Copyright"}],"article-number":"101161"}}