{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T17:51:23Z","timestamp":1781891483405,"version":"3.54.5"},"reference-count":25,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Research in Translational Medicine"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.retram.2026.103587","type":"journal-article","created":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T23:46:36Z","timestamp":1776815196000},"page":"103587","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Generalized skeletal sclerosis as a potential late effect of total body irradiation after allogeneic hematopoietic stem cell transplantation: A case report"],"prefix":"10.1016","volume":"74","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-5131-4177","authenticated-orcid":false,"given":"Bakoubass\u00e9 A\u00efssata","family":"Son","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucie","family":"Lemeunier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yazid","family":"Belkacemi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Remy","family":"Dulery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamad","family":"Mohty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Micka\u00ebl","family":"Rousi\u00e8re","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lise","family":"Minssen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Denis","family":"Laredo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis","family":"Berenbaum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabryne","family":"Berkani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8122-701X","authenticated-orcid":false,"given":"Alice","family":"Courties","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.retram.2026.103587_bib0001","doi-asserted-by":"crossref","first-page":"A63\u20114","DOI":"10.1016\/j.rhum.2020.10.103","article-title":"Fr\u00e9quence et \u00e9tiologies des hyperdensit\u00e9s osseuses : r\u00e9sultats d\u2019une \u00e9tude Fran\u00e7aise multicentrique","volume":"87","author":"Paccou","year":"2020","journal-title":"Rev du Rhum"},{"issue":"1","key":"10.1016\/j.retram.2026.103587_bib0002","doi-asserted-by":"crossref","first-page":"1\u20116","DOI":"10.1385\/JCD:8:1:001","article-title":"Misinterpretation of osteodensitometry with high bone density: BMD Z >or = + 2.5 is not \u00ab normal \u00bb","volume":"8","author":"Whyte","year":"2005","journal-title":"J Clin Densitom"},{"key":"10.1016\/j.retram.2026.103587_bib0003","doi-asserted-by":"crossref","first-page":"362","DOI":"10.4103\/ijri.IJRI_495_19","article-title":"Technical and patient-related sources of error and artifacts in bone mineral densitometry using dual-energy X-ray absorptiometry: a pictorial review","volume":"30","author":"Qutbi","year":"2020","journal-title":"Indian J Radiol Imaging"},{"key":"10.1016\/j.retram.2026.103587_bib0004","doi-asserted-by":"crossref","DOI":"10.1155\/2011\/560257","article-title":"Feasibility of treating irradiated bone with intramedullary delivered autologous mesenchymal stem cells","volume":"2011","author":"Phulpin","year":"2011","journal-title":"BioMed Res Int"},{"key":"10.1016\/j.retram.2026.103587_bib0005","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1186\/s13014-015-0368-x","article-title":"Bone density as a marker for local response to radiotherapy of spinal bone metastases in women with breast cancer: a retrospective analysis","volume":"10","author":"Foerster","year":"2015","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.retram.2026.103587_bib0006","article-title":"Remineralization of lytic spinal metastases after radiation therapy \u2013 A retrospective cohort study comparing conventional external beam radiation therapy with stereotactic ablative body radiation","volume":"48","author":"Van Den","year":"2024","journal-title":"Clin Transl Radiat Oncol"},{"key":"10.1016\/j.retram.2026.103587_bib0007","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1093\/rheumatology\/ket007","article-title":"Friend or foe: high bone mineral density on routine bone density scanning, a review of causes and management","volume":"52","author":"Gregson","year":"2013","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.retram.2026.103587_bib0008","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1182\/blood.2023019804","article-title":"How I treat long-term survivors of childhood acute leukemia","volume":"143","author":"Saultier","year":"2024","journal-title":"Blood"},{"key":"10.1016\/j.retram.2026.103587_bib0009","article-title":"Adverse effects of total body irradiation: a two-decade, single institution analysis","volume":"6","author":"Pearlman","year":"2021","journal-title":"Adv. Radiat. Oncol"},{"key":"10.1016\/j.retram.2026.103587_bib0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1278-3218(01)00142-1","article-title":"Radion\u00e9crose de l\u2019os mature : connaissance physiopathologique r\u00e9cente motrice d\u2019une th\u00e9rapeutique m\u00e9dicale innovante","volume":"6","author":"Delanian","year":"2002","journal-title":"Cancer\/Radioth\u00e9rapie"},{"issue":"3","key":"10.1016\/j.retram.2026.103587_bib0011","doi-asserted-by":"crossref","first-page":"193","DOI":"10.7150\/ijms.3635","article-title":"Cancer and radiation therapy: current advances and future directions","volume":"9","author":"Baskar","year":"2012","journal-title":"Int J Med Sci"},{"key":"10.1016\/j.retram.2026.103587_bib0012","doi-asserted-by":"crossref","unstructured":"Jegoux F., Malard O., Goyenvalle E., et al. Radiation effects on bone healing and reconstruction: interpretation of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109:173\u201384. https:\/\/doi.org\/10.1016\/j.tripleo.2009.10.001.","DOI":"10.1016\/j.tripleo.2009.10.001"},{"issue":"6","key":"10.1016\/j.retram.2026.103587_bib0013","article-title":"Bone density changes following radiotherapy to vertebral metastases","volume":"13","author":"Jensen","year":"2021","journal-title":"Cureus"},{"issue":"4","key":"10.1016\/j.retram.2026.103587_bib0014","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.spinee.2022.12.018","article-title":"Remineralization of lytic spinal metastases after radiotherapy","volume":"23","author":"Pielkenrood","year":"2023","journal-title":"Spine J"},{"key":"10.1016\/j.retram.2026.103587_bib0015","series-title":"Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism","first-page":"788","article-title":"Radiotherapy-Induced Osteoporosis","author":"Wright","year":"2018"},{"issue":"6","key":"10.1016\/j.retram.2026.103587_bib0016","first-page":"332","article-title":"The remineralization of the vertebral metastases of breast carcinoma after radiotherapy","volume":"172","author":"Wachenfeld","year":"1996","journal-title":"Strahlenther Onkol"},{"key":"10.1016\/j.retram.2026.103587_bib0017","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1007\/s00256-017-2706-6","article-title":"Quantitative contrast-enhanced CT attenuation evaluation of osseous metastases following chemotherapy","volume":"46","author":"Chang","year":"2017","journal-title":"Skeletal Radiol"},{"key":"10.1016\/j.retram.2026.103587_bib0018","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1002\/jbmr.2458","article-title":"Single-limb irradiation induces local and systemic bone loss in a murine model","volume":"30","author":"Wright","year":"2015","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.retram.2026.103587_bib0019","article-title":"Low-dose X-ray irradiation promotes osteoblast proliferation, differentiation and fracture healing","volume":"9","author":"Chen","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.retram.2026.103587_bib0020","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1093\/jrr\/rrx026","article-title":"Differences in responses to X-ray exposure between osteoclast and osteoblast cells","volume":"58","author":"Zhang","year":"2017","journal-title":"J Radiat Res"},{"key":"10.1016\/j.retram.2026.103587_bib0021","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-024-75363-8","article-title":"Total body irradiation is associated with long-term deficits in femoral bone structure but not mechanical properties in male rhesus macaques","volume":"14","author":"Barnet","year":"2024","journal-title":"Sci Rep"},{"key":"10.1016\/j.retram.2026.103587_bib0022","doi-asserted-by":"crossref","first-page":"e2100","DOI":"10.1210\/clinem\/dgae042","article-title":"Characterization and predictors of fractures following hematopoietic stem cell transplantation","volume":"109","author":"Tsai","year":"2024","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.retram.2026.103587_bib0023","doi-asserted-by":"crossref","first-page":"267","DOI":"10.3390\/ijms22010267","article-title":"Spatio-temporal bone remodeling after hematopoietic stem cell transplantation","volume":"22","author":"Schwarz","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.retram.2026.103587_bib0024","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/1750-1172-4-5","volume":"4","author":"Stark","year":"2009","journal-title":"Orphanet J Rare Dis"},{"key":"10.1016\/j.retram.2026.103587_bib0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.jposna.2024.100054","article-title":"Bone health: quality versus quantity","volume":"7","author":"Docaj","year":"2024","journal-title":"J Pediatr Orthop Soc N Am"}],"container-title":["Current Research in Translational Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452318626000231?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452318626000231?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T16:57:32Z","timestamp":1781888252000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2452318626000231"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["S2452318626000231"],"URL":"https:\/\/doi.org\/10.1016\/j.retram.2026.103587","relation":{},"ISSN":["2452-3186"],"issn-type":[{"value":"2452-3186","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Generalized skeletal sclerosis as a potential late effect of total body irradiation after allogeneic hematopoietic stem cell transplantation: A case report","name":"articletitle","label":"Article Title"},{"value":"Current Research in Translational Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.retram.2026.103587","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Masson SAS. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"103587"}}