{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T19:50:50Z","timestamp":1786996250157,"version":"build-2736575974"},"reference-count":15,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Reumatolog\u00eda Cl\u00ednica"],"published-print":{"date-parts":[[2018,5]]},"DOI":"10.1016\/j.reuma.2016.10.011","type":"journal-article","created":{"date-parts":[[2016,12,28]],"date-time":"2016-12-28T10:03:38Z","timestamp":1482919418000},"page":"160-163","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"title":["Clinical phenotype and outcome in lupus according to age: a comparison between juvenile and adult onset"],"prefix":"10.1016","volume":"14","author":[{"given":"Rita","family":"Fonseca","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisca","family":"Aguiar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana","family":"Rodrigues","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iva","family":"Brito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.reuma.2016.10.011_bib0080","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/S0889-857X(02)00015-7","article-title":"Systemic lupus erythematosus in childhood","volume":"28","author":"Klein-Gitelman","year":"2002","journal-title":"Rheum Dis Clin N Am"},{"key":"10.1016\/j.reuma.2016.10.011_bib0085","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1002\/acr.21757","article-title":"Taxonomy for systemic lupus erythematosus with onset before adulthood","volume":"64","author":"Silva","year":"2012","journal-title":"Arthritis Care Res"},{"key":"10.1016\/j.reuma.2016.10.011_bib0090","first-page":"274","article-title":"Juvenile systemic lupus erythematosus in Portugal: clinical and immunological patterns of disease expression in a cohort of 56 patients","volume":"38","author":"Cabral","year":"2013","journal-title":"Acta Reumatol Port"},{"key":"10.1016\/j.reuma.2016.10.011_bib0095","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1177\/0961203314563817","article-title":"Similarities and differences between pediatric and adult patients with systemic lupus erythematosus","volume":"24","author":"Tarr","year":"2015","journal-title":"Lupus"},{"key":"10.1016\/j.reuma.2016.10.011_bib0100","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1177\/0961203313513508","article-title":"Associations of clinical features and prognosis with age at disease onset in patients with systemic lupus erythematosus","volume":"23","author":"Feng","year":"2014","journal-title":"Lupus"},{"key":"10.1016\/j.reuma.2016.10.011_bib0105","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1093\/rheumatology\/ket488","article-title":"A comparison of the outcome of adolescent and adult-onset systemic lupus erythematosus","volume":"53","author":"Amaral","year":"2014","journal-title":"Rheumatology"},{"key":"10.1016\/j.reuma.2016.10.011_bib0110","doi-asserted-by":"crossref","DOI":"10.1177\/0961203316644333","article-title":"Differences in disease phenotype and severity in SLE across age groups","author":"Ambrose","year":"2016","journal-title":"Lupus"},{"key":"10.1016\/j.reuma.2016.10.011_bib0115","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1177\/0961203307088006","article-title":"Childhood systemic lupus erythematosus in Latin America. The GLADEL experience in 230 children","volume":"17","author":"Ram\u00edrez G\u00f3mez","year":"2008","journal-title":"Lupus"},{"key":"10.1016\/j.reuma.2016.10.011_bib0120","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1177\/0961203307087875","article-title":"Adolescent onset of lupus results in more aggressive disease and worse outcomes: results of a nested matched case\u2013control study within LUMINA, a multiethnic US cohort (LUMINA LVII)","volume":"17","author":"Tucker","year":"2008","journal-title":"Lupus"},{"key":"10.1016\/j.reuma.2016.10.011_bib0125","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1002\/art.23204","article-title":"Difference in disease features between childhood-onset and adult-onset systemic lupus erythematosus","volume":"58","author":"Brunner","year":"2008","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.reuma.2016.10.011_bib0130","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1002\/art.1780400928","article-title":"Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus","volume":"40","author":"Hochberg","year":"1997","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.reuma.2016.10.011_bib0135","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1177\/0961203314555172","article-title":"Characterization of damage in Portuguese lupus patients: analysis of a national lupus registry","volume":"24","author":"Gonc","year":"2015","journal-title":"Lupus"},{"key":"10.1016\/j.reuma.2016.10.011_bib0140","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1177\/0961203311416694","article-title":"Differences in clinical manifestations between childhood-onset lupus and adult-onset lupus: a meta-analysis","volume":"20","author":"Livingston","year":"2011","journal-title":"Lupus"},{"key":"10.1016\/j.reuma.2016.10.011_bib0145","first-page":"255","article-title":"Clinical and immunological aspects and outcome of a Brazilian cohort of 414 patients with systemic lupus erythematosus (SLE): comparison between childhood-onset, adult-onset, and late-onset SLE","volume":"25","author":"Medeiros","year":"2016","journal-title":"Lupus"},{"key":"10.1016\/j.reuma.2016.10.011_bib0150","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1136\/ard.57.8.456","article-title":"Systemic lupus erythematosus (SLE) in childhood: analysis of clinical and immunological findings in 34 patients and comparison with SLE characteristics in adults","volume":"57","author":"Font","year":"1998","journal-title":"Ann Rheum Dis"}],"container-title":["Reumatolog\u00eda Cl\u00ednica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1699258X16301565?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1699258X16301565?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,5]],"date-time":"2018-09-05T09:24:22Z","timestamp":1536139462000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1699258X16301565"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,5]]}},"alternative-id":["S1699258X16301565"],"URL":"https:\/\/doi.org\/10.1016\/j.reuma.2016.10.011","relation":{},"ISSN":["1699-258X"],"issn-type":[{"value":"1699-258X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical phenotype and outcome in lupus according to age: a comparison between juvenile and adult onset","name":"articletitle","label":"Article Title"},{"value":"Reumatolog\u00eda Cl\u00ednica","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.reuma.2016.10.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Espa\u00f1a, S.L.U. and Sociedad Espa\u00f1ola de Reumatolog\u00eda y Colegio Mexicano de Reumatolog\u00eda. All rights reserved.","name":"copyright","label":"Copyright"}]}}