{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:23:36Z","timestamp":1762507416769,"version":"build-2065373602"},"reference-count":28,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Reumatolog\u00eda Cl\u00ednica"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1016\/j.reuma.2018.02.016","type":"journal-article","created":{"date-parts":[[2018,5,17]],"date-time":"2018-05-17T19:05:58Z","timestamp":1526583958000},"page":"110-115","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"P1","title":["La vitamina D no es \u00fatil como biomarcador para la actividad de la enfermedad en artritis reumatoide"],"prefix":"10.1016","volume":"16","author":[{"given":"Paola","family":"de la Torre Lossa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Moreno \u00c1lvarez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda del Carmen","family":"Gonz\u00e1lez Guzm\u00e1n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael","family":"L\u00f3pez Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"R\u00edos Acosta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.reuma.2018.02.016_bib0145","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2015\/913804","article-title":"Association between serum 25-hydroxyvitamin D level and rheumatoid arthritis","volume":"2015","author":"Cen","year":"2015","journal-title":"BioMed Res Int."},{"key":"10.1016\/j.reuma.2018.02.016_bib0150","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1136\/ard.2007.069831","article-title":"Vitamin D and autoimmunity: New aetiological and therapeutic considerations","volume":"66","author":"Arnson","year":"2007","journal-title":"Ann Rheum Dis."},{"key":"10.1016\/j.reuma.2018.02.016_bib0155","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.reuma.2015.11.001","article-title":"Vitamina D y enfermedades autoinmunes reum\u00e1ticas","volume":"11","author":"Garc\u00eda-Carrasco","year":"2015","journal-title":"Reumatol Clin."},{"key":"10.1016\/j.reuma.2018.02.016_bib0160","first-page":"1379","article-title":"Vitamin D and mortality","volume":"36","author":"Pilz","year":"2016","journal-title":"Anticancer Res."},{"key":"10.1016\/j.reuma.2018.02.016_bib0165","doi-asserted-by":"crossref","first-page":"2671","DOI":"10.2174\/0929867323666161220105821","article-title":"Vitamin D: Autoimmunity and gender","volume":"24","author":"Crescioli","year":"2017","journal-title":"Curr Med Chem."},{"key":"10.1016\/j.reuma.2018.02.016_bib0170","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.2174\/1568026615666150915111557","article-title":"The roles of vitamin D and its analogs in inflammatory diseases","volume":"16","author":"Lin","year":"2016","journal-title":"Curr Top Med Chem."},{"key":"10.1016\/j.reuma.2018.02.016_bib0175","unstructured":"Firestein GS. Pathogenesis of rheumatoid arthritis [Internet]. UpToDate [consultado 18 Jul 2017]. Disponible en: https:\/\/www.uptodate.com\/contents\/pathogenesis-of-rheumatoid-arthritis?source=search_result&search=artritis%20reumatoide&selectedTitle=6\u223c150"},{"key":"10.1016\/j.reuma.2018.02.016_bib0180","doi-asserted-by":"crossref","first-page":"e0146351","DOI":"10.1371\/journal.pone.0146351","article-title":"Vitamin D level and rheumatoid arthritis disease activity: Review and meta-analysis","volume":"11","author":"Lin","year":"2016","journal-title":"PloS One."},{"key":"10.1016\/j.reuma.2018.02.016_bib0185","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1007\/s10067-012-2080-7","article-title":"Association between vitamin D intake and the risk of rheumatoid arthritis: A meta-analysis","volume":"31","author":"Song","year":"2012","journal-title":"Clin Rheumatol."},{"key":"10.1016\/j.reuma.2018.02.016_bib0190","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1007\/s00296-014-3019-x","article-title":"Low vitamin D level is not associated with increased incidence of rheumatoid arthritis","volume":"34","author":"Cote","year":"2014","journal-title":"Rheumatol Int."},{"key":"10.1016\/j.reuma.2018.02.016_bib0195","first-page":"610","article-title":"Is there an association between serum 25-hydroxyvitamin D concentrations and disease activity in rheumatoid arthritis?","volume":"113","author":"Baykal","year":"2012","journal-title":"Bratisl Lek Listy."},{"key":"10.1016\/j.reuma.2018.02.016_bib0200","first-page":"205","article-title":"Prevalence of vitamin D levels in patients with autoimmune diseases in Ecuador: A retrospective study","volume":"24","author":"Maldonado Velez","year":"2017","journal-title":"Rev Colomb Reumatol."},{"key":"10.1016\/j.reuma.2018.02.016_bib0205","first-page":"207","article-title":"2011 Consensus of the Brazilian Society of Rheumatology for diagnosis and early assessment of rheumatoid arthritis","volume":"51","author":"Da Mota","year":"2011","journal-title":"Rev Bras Reumatol."},{"key":"10.1016\/j.reuma.2018.02.016_bib0210","doi-asserted-by":"crossref","first-page":"E610","DOI":"10.1503\/cmaj.080663","article-title":"Vitamin D in adult health and disease: A review and guideline statement from Osteoporosis Canada","volume":"182","author":"Hanley","year":"2010","journal-title":"Can Med Assoc J."},{"key":"10.1016\/j.reuma.2018.02.016_bib0215","doi-asserted-by":"crossref","first-page":"3831275","DOI":"10.1155\/2017\/3831275","article-title":"Determination of vitamin D status in a population of Ecuadorian subjects","volume":"2017","author":"Maldonado","year":"2017","journal-title":"Scientific World Journal."},{"key":"10.1016\/j.reuma.2018.02.016_bib0220","doi-asserted-by":"crossref","first-page":"545297","DOI":"10.1155\/2015\/545297","article-title":"Vitamin D status among older adults residing in the Littoral and Andes Mountains in Ecuador","volume":"2015","author":"Orces","year":"2015","journal-title":"Scientific World Journal."},{"key":"10.1016\/j.reuma.2018.02.016_bib0225","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1111\/1756-185X.12222","article-title":"The association between serum vitamin D Level and disease activity in Thai rheumatoid arthritis patients","volume":"19","author":"Pakchotanon","year":"2016","journal-title":"Int J Rheum Dis."},{"key":"10.1016\/j.reuma.2018.02.016_bib0230","doi-asserted-by":"crossref","first-page":"246","DOI":"10.3109\/14397595.2014.952487","article-title":"Relationships between serum 25-hydroxycalciferol, vitamin D intake and disease activity in patients with rheumatoid arthritis \u2013TOMORROW study","volume":"25","author":"Matsumoto","year":"2015","journal-title":"Mod Rheumatol."},{"key":"10.1016\/j.reuma.2018.02.016_bib0235","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1007\/s00296-014-3071-6","article-title":"Vitamin D levels and bone mass in rheumatoid arthritis","volume":"35","author":"Brance","year":"2015","journal-title":"Rheumatol Int."},{"key":"10.1016\/j.reuma.2018.02.016_bib0240","doi-asserted-by":"crossref","DOI":"10.1136\/annrheumdis-2017-eular.5977","article-title":"THU0116 European multicentre pilot survey to assess vitamin d and clinical status in rheumatoid arthritis patients","volume":"76","author":"Cutolo","year":"2017","journal-title":"Ann Rheum Dis."},{"key":"10.1016\/j.reuma.2018.02.016_bib0245","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1097\/BOR.0000000000000397","article-title":"Vitamin D and rheumatoid arthritis: An ongoing mystery","volume":"29","author":"Bragazzi","year":"2017","journal-title":"Curr Opin Rheumatol."},{"key":"10.1016\/j.reuma.2018.02.016_bib0250","first-page":"827","article-title":"Vitamin D level in rheumatoid arthritis and its correlation with the disease activity: a meta-analysis","volume":"34","author":"Lee","year":"2016","journal-title":"Clin Exp Rheumatol."},{"key":"10.1016\/j.reuma.2018.02.016_bib0255","doi-asserted-by":"crossref","first-page":"5491676","DOI":"10.1155\/2017\/5491676","article-title":"Evaluation of vitamin D status in rheumatoid arthritis and its association with disease activity across 15 countries: \u201cThe COMORA Study\u201d","volume":"2017","author":"Hajjaj-Hassouni","year":"2017","journal-title":"Int J Rheumatol."},{"key":"10.1016\/j.reuma.2018.02.016_bib0260","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1590\/1678-98652017000400002","article-title":"Body composition and metabolic profile in adults with vitamin D deficiency","volume":"30","author":"Rocha","year":"2017","journal-title":"Rev Nutr."},{"key":"10.1016\/j.reuma.2018.02.016_bib0265","first-page":"211","article-title":"Vitamina D y dolor cr\u00f3nico","volume":"23","author":"Alc\u00e1ntara Montero","year":"2016","journal-title":"Rev Soc Esp Dolor."},{"key":"10.1016\/j.reuma.2018.02.016_bib0270","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2016\/8920503","article-title":"Nationality, gender, age, and body mass index influences on vitamin D concentration among elderly patients and young Iraqi and Jordanian in Jordan","volume":"2016","author":"Al-Horani","year":"2016","journal-title":"Biochem Res Int."},{"key":"10.1016\/j.reuma.2018.02.016_bib0275","first-page":"112","article-title":"An evaluation of high-dose vitamin D for rheumatoid arthritis","volume":"20","author":"Hansen","year":"2014","journal-title":"J Clin Rheumatol Pract Rep Rheum Musculoskelet Dis."},{"key":"10.1016\/j.reuma.2018.02.016_bib0280","first-page":"714","article-title":"Determinants and effects of vitamin D supplementation on serum 25-hydroxy-vitamin D levels in patients with rheumatoid arthritis","volume":"30","author":"Varenna","year":"2012","journal-title":"Clin Exp Rheumatol."}],"container-title":["Reumatolog\u00eda Cl\u00ednica"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1699258X18300779?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1699258X18300779?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T14:59:23Z","timestamp":1761663563000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1699258X18300779"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3]]},"references-count":28,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["S1699258X18300779"],"URL":"https:\/\/doi.org\/10.1016\/j.reuma.2018.02.016","relation":{},"ISSN":["1699-258X"],"issn-type":[{"type":"print","value":"1699-258X"}],"subject":[],"published":{"date-parts":[[2020,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"La vitamina D no es \u00fatil como biomarcador para la actividad de la enfermedad en artritis reumatoide","name":"articletitle","label":"Article Title"},{"value":"Reumatolog\u00eda Cl\u00ednica","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.reuma.2018.02.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Sociedad Espa\u00f1ola de Reumatolog\u00eda y Colegio Mexicano de Reumatolog\u00eda. Published by Elsevier Espa\u00f1a, S.L.U. All rights reserved.","name":"copyright","label":"Copyright"}]}}