{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T12:06:10Z","timestamp":1790856370463,"version":"4.1.0"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T00:00:00Z","timestamp":1788912000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["La Revue de M\u00e9decine Interne"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.revmed.2026.09.007","type":"journal-article","created":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T11:15:46Z","timestamp":1790853346000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Dosage raisonn\u00e9 des troponines"],"prefix":"10.1016","author":[{"given":"J\u00e9r\u00e9my","family":"Boyer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Cautela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.revmed.2026.09.007_bib0145","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.gene.2016.01.006","article-title":"TNNT1, TNNT2, and TNNT3: isoform genes, regulation, and structure\u00a0\u2013\u00a0function relationships","volume":"582","author":"Wei","year":"2016","journal-title":"Gene"},{"issue":"24","key":"10.1016\/j.revmed.2026.09.007_bib0150","doi-asserted-by":"crossref","first-page":"2406","DOI":"10.1016\/j.jacc.2011.01.029","article-title":"Pathobiology of troponin elevations: do elevations occur with myocardial ischemia as well as necrosis?","volume":"57","author":"White","year":"2011","journal-title":"J Am Coll Cardiol"},{"issue":"3","key":"10.1016\/j.revmed.2026.09.007_bib0155","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1093\/eurheartj\/ehy462","article-title":"Fourth universal definition of myocardial infarction (2018)","volume":"40","author":"Thygesen","year":"2019","journal-title":"Eur Heart J"},{"issue":"38","key":"10.1016\/j.revmed.2026.09.007_bib0160","doi-asserted-by":"crossref","first-page":"3720","DOI":"10.1093\/eurheartj\/ehad191","article-title":"ESC Scientific Document Group 2023\u00a0ESC guidelines for the management of acute coronary syndromes","volume":"44","author":"Byrne","year":"2023","journal-title":"Eur Heart J"},{"issue":"4","key":"10.1016\/j.revmed.2026.09.007_bib0165","doi-asserted-by":"crossref","first-page":"348","DOI":"10.21037\/cdt.2017.03.21","article-title":"Type 2\u00a0versus type 1\u00a0myocardial infarction: a comparison of clinical characteristics and outcomes with a meta-analysis of observational studies","volume":"7","author":"Gupta","year":"2017","journal-title":"Cardiovasc Diagn Ther"},{"issue":"3","key":"10.1016\/j.revmed.2026.09.007_bib0170","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.amjmed.2014.09.029","article-title":"Prognostic comparison of different sensitivity cardiac troponin assays in stable heart failure","volume":"128","author":"Grodin","year":"2015","journal-title":"Am J Med"},{"issue":"Suppl 2","key":"10.1016\/j.revmed.2026.09.007_bib0175","first-page":"2078","article-title":"High sensitivity troponin I in hypertrophic cardiomyopathy","volume":"41","author":"Osmanska","year":"2020","journal-title":"Eur Heart J"},{"issue":"22","key":"10.1016\/j.revmed.2026.09.007_bib0180","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1093\/eurheartj\/ehy077","article-title":"International expert consensus document on Takotsubo syndrome (Part II): diagnostic workup, outcome, and management","volume":"39","author":"Ghadri","year":"2018","journal-title":"Eur Heart J"},{"issue":"21","key":"10.1016\/j.revmed.2026.09.007_bib0185","doi-asserted-by":"crossref","first-page":"2085","DOI":"10.1161\/CIRCULATIONAHA.117.030571","article-title":"Clinical features, management, and outcomes of immune checkpoint inhibitor\u00a0\u2013\u00a0related cardiotoxicity","volume":"136","author":"Escudier","year":"2017","journal-title":"Circulation"},{"issue":"9","key":"10.1016\/j.revmed.2026.09.007_bib0190","doi-asserted-by":"crossref","first-page":"e1014","DOI":"10.1002\/iid3.1014","article-title":"Cardiac troponin as a prognosticator of mortality in patients with sepsis: a systematic review and meta-analysis","volume":"11","author":"Zheng","year":"2023","journal-title":"Immun Inflamm Dis"},{"issue":"9","key":"10.1016\/j.revmed.2026.09.007_bib0195","doi-asserted-by":"crossref","first-page":"e038651","DOI":"10.1161\/JAHA.124.038651","article-title":"Impact of elevated troponin level at the time of sepsis recognition on the clinical outcomes: a propensity score-matched cohort study","volume":"14","author":"Choi","year":"2025","journal-title":"J Am Heart Assoc"},{"issue":"11","key":"10.1016\/j.revmed.2026.09.007_bib0200","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1016\/S0735-1097(03)00421-2","article-title":"Troponin as a risk factor for mortality in critically ill patients without acute coronary syndromes","volume":"41","author":"Ammann","year":"2003","journal-title":"J Am Coll Cardiol"},{"issue":"10","key":"10.1016\/j.revmed.2026.09.007_bib0205","first-page":"1187","article-title":"The association of anaemia and high-sensitivity cardiac troponin and its effect on diagnosing myocardial infarction","volume":"10","author":"Haller","year":"2021","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"issue":"Suppl_3","key":"10.1016\/j.revmed.2026.09.007_bib0210","doi-asserted-by":"crossref","first-page":"A15990","DOI":"10.1161\/circ.142.suppl_3.15990","article-title":"Abstract 15990: incidence and outcomes of elevated troponins in patients with rhabdomyolysis","volume":"142","author":"Ganta","year":"2020","journal-title":"Circulation"},{"issue":"23","key":"10.1016\/j.revmed.2026.09.007_bib0215","doi-asserted-by":"crossref","first-page":"2941","DOI":"10.1161\/01.CIR.0000041254.30637.34","article-title":"Predictive value of cardiac troponin I and T for subsequent death in end-stage renal disease","volume":"106","author":"Apple","year":"2002","journal-title":"Circulation"},{"issue":"7","key":"10.1016\/j.revmed.2026.09.007_bib0220","first-page":"546","article-title":"Diagnosis of acute myocardial infarction in patients with renal failure using high-sensitivity cardiac troponin T","volume":"13","author":"Knott","year":"2024","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"issue":"20","key":"10.1016\/j.revmed.2026.09.007_bib0225","doi-asserted-by":"crossref","first-page":"2316","DOI":"10.3390\/diagnostics14202316","article-title":"Cardiac troponin levels in patients with chronic kidney disease: \u201cmarkers of high risk or just noise\u201d?","volume":"14","author":"Geladari","year":"2024","journal-title":"Diagnostics"},{"issue":"8","key":"10.1016\/j.revmed.2026.09.007_bib0230","doi-asserted-by":"crossref","first-page":"e2419602","DOI":"10.1001\/jamanetworkopen.2024.19602","article-title":"Acute kidney injury and high-sensitivity cardiac troponin T levels in the emergency department","volume":"7","author":"Cyon","year":"2024","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.revmed.2026.09.007_bib0235","doi-asserted-by":"crossref","DOI":"10.1016\/j.amjcard.2025.05.020","article-title":"Prognostic implications of high-sensitivity cardiac troponins in patients with acute kidney injury without myocardial infarction","author":"Cyon","year":"2025","journal-title":"Am J Cardiol"},{"issue":"12","key":"10.1016\/j.revmed.2026.09.007_bib0240","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1016\/S1474-4422(18)30336-3","article-title":"Stroke\u00a0\u2013\u00a0heart syndrome: clinical presentation and underlying mechanisms","volume":"17","author":"Scheitz","year":"2018","journal-title":"Lancet Neurol"},{"issue":"12","key":"10.1016\/j.revmed.2026.09.007_bib0245","first-page":"e99338","article-title":"Thyroid storm with myocardial injury mimicking acute coronary syndrome: a case report and literature review","volume":"17","author":"Chamma","year":"2025","journal-title":"Cureus"},{"issue":"2","key":"10.1016\/j.revmed.2026.09.007_bib0250","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1002\/clc.20167","article-title":"Positive troponin in diabetic ketoacidosis without evident acute coronary syndrome predicts adverse cardiac events","volume":"31","author":"Al-Mallah","year":"2008","journal-title":"Clin Cardiol"},{"key":"10.1016\/j.revmed.2026.09.007_bib0255","doi-asserted-by":"crossref","first-page":"1204851","DOI":"10.3389\/fendo.2023.1204851","article-title":"Pheochromocytoma\/paraganglioma-associated cardiomyopathy","volume":"14","author":"Szatko","year":"2023","journal-title":"Front Endocrinol"},{"issue":"2","key":"10.1016\/j.revmed.2026.09.007_bib0260","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1002\/ehf2.15058","article-title":"Prognostic role of high-sensitivity cardiac troponin T in patients with cardiac sarcoidosis: insights from ILLUMINATE-CS","volume":"12","author":"Baba","year":"2025","journal-title":"ESC Heart Failure"},{"issue":"11","key":"10.1016\/j.revmed.2026.09.007_bib0265","doi-asserted-by":"crossref","first-page":"42760","DOI":"10.31083\/RCM42760","article-title":"Cardiac involvement in systemic lupus erythematosus","volume":"26","author":"Vyas","year":"2025","journal-title":"Rev Cardiovasc Med"},{"issue":"24","key":"10.1016\/j.revmed.2026.09.007_bib0270","doi-asserted-by":"crossref","first-page":"1764","DOI":"10.1161\/CIRCULATIONAHA.121.058489","article-title":"Skeletal muscle disorders: a noncardiac source of cardiac troponin T","volume":"145","author":"du Fay de Lavallaz","year":"2022","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.revmed.2026.09.007_bib0275","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/s12185-008-0112-5","article-title":"Cardiac toxicity of high-dose cyclophosphamide and melphalan in patients with multiple myeloma treated with tandem autologous hematopoietic stem cell transplantation","volume":"88","author":"Zver","year":"2008","journal-title":"Int J Hematol"},{"key":"10.1016\/j.revmed.2026.09.007_bib0140","doi-asserted-by":"crossref","first-page":"932347","DOI":"10.3389\/fcvm.2022.932347","article-title":"Cardiovascular disease and chimeric antigen receptor cellular therapy","volume":"9","author":"Rao","year":"2022","journal-title":"Front Cardiovasc Med"}],"container-title":["La Revue de M\u00e9decine Interne"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0248866326007344?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0248866326007344?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T11:15:50Z","timestamp":1790853350000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0248866326007344"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":28,"alternative-id":["S0248866326007344"],"URL":"https:\/\/doi.org\/10.1016\/j.revmed.2026.09.007","relation":{},"ISSN":["0248-8663"],"issn-type":[{"value":"0248-8663","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dosage raisonn\u00e9 des troponines","name":"articletitle","label":"Article Title"},{"value":"La Revue de M\u00e9decine Interne","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.revmed.2026.09.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Masson SAS on behalf of Soci\u00e9t\u00e9 Nationale Fran\u00e7aise de M\u00e9decine Interne (SNFMI).","name":"copyright","label":"Copyright"}]}}