{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:35:35Z","timestamp":1787168135811,"version":"build-2736575974"},"reference-count":148,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T00:00:00Z","timestamp":1396310400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,3,2]],"date-time":"2015-03-02T00:00:00Z","timestamp":1425254400000},"content-version":"vor","delay-in-days":335,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revista de Gastroenterolog\u00eda de M\u00e9xico"],"published-print":{"date-parts":[[2014,4]]},"DOI":"10.1016\/j.rgmx.2014.01.004","type":"journal-article","created":{"date-parts":[[2014,5,23]],"date-time":"2014-05-23T00:47:22Z","timestamp":1400806042000},"page":"96-134","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Microbiota, infecciones gastrointestinales, inflamaci\u00f3n de bajo grado y antibioticoterapia en el s\u00edndrome de intestino irritable. Una revisi\u00f3n basada en evidencias"],"prefix":"10.1016","volume":"79","author":[{"given":"M.","family":"Schmulson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.V.","family":"Bielsa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Carmona-S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"L\u00f3pez-Colombo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"L\u00f3pez Vidal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Pel\u00e1ez-Luna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.M.","family":"Remes-Troche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.L.","family":"Tamayo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.A.","family":"Valdovinos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.rgmx.2014.01.004_bib0005","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.gtc.2010.12.004","article-title":"Traditional thoughts on the pathophysiology of irritable bowel syndrome","volume":"40","author":"Hasler","year":"2011","journal-title":"Gastroenterol Clin North Am"},{"issue":"Suppl 3","key":"10.1016\/j.rgmx.2014.01.004_bib0010","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1111\/j.1440-1746.2011.06643.x","article-title":"Post-infectious irritable bowel syndrome: The past, the present and the future","volume":"26","author":"Ghoshal","year":"2011","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0015","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1016\/j.cgh.2009.06.031","article-title":"Small intestinal bacterial overgrowth in irritable bowel syndrome: Systematic review and meta-analysis","volume":"7","author":"Ford","year":"2009","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0020","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1136\/gutjnl-2012-302167","article-title":"Intestinal microbiota in functional bowel disorders: A Rome foundation report","volume":"62","author":"Simren","year":"2013","journal-title":"Gut"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0025","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1007\/s00535-011-0379-9","article-title":"Mucosal inflammation as a potential etiological factor in irritable bowel syndrome: A systematic review","volume":"46","author":"Ford","year":"2011","journal-title":"J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0030","first-page":"711","article-title":"Irritable bowel syndrome immune hypothesis. Part two: The role of cytokines","volume":"102","author":"Ortiz-Lucas","year":"2010","journal-title":"Rev Esp Enferm Dig"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0035","doi-asserted-by":"crossref","first-page":"363","DOI":"10.5056\/jnm.2010.16.4.363","article-title":"From cytokines to toll-like receptors and beyond \u2014 current knowledge and future research needs in irritable bowel syndrome","volume":"16","author":"Rodriguez-Fandino","year":"2010","journal-title":"J Neurogastroenterol Motil"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0040","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1007\/s11894-012-0284-2","article-title":"Antibiotics for irritable bowel syndrome: Rationale and current evidence","volume":"14","author":"Sachdev","year":"2012","journal-title":"Curr Gastroenterol Rep"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0045","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.cgh.2011.02.030","article-title":"Questioning the bacterial overgrowth hypothesis of irritable bowel syndrome: An epidemiologic and evolutionary perspective","volume":"9","author":"Spiegel","year":"2011","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0050","doi-asserted-by":"crossref","first-page":"2267","DOI":"10.1038\/ajg.2009.302","article-title":"Development and validation of a risk score for post-infectious irritable bowel syndrome","volume":"104","author":"Thabane","year":"2009","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0055","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1111\/j.1572-0241.2008.01785.x","article-title":"Lactulose breath testing does not discriminate patients with irritable bowel syndrome from healthy controls","volume":"103","author":"Bratten","year":"2008","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0060","doi-asserted-by":"crossref","first-page":"995","DOI":"10.3109\/00365521.2013.799220","article-title":"Microbiota in health and irritable bowel syndrome: Current knowledge, perspectives and therapeutic options","volume":"48","author":"Bonfrate","year":"2013","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0065","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1038\/ajg.2011.427","article-title":"Abnormal immune regulation and low-grade inflammation in IBS: Does one size fit all? [editorial]","volume":"107","author":"Schmulson","year":"2012","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0070","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1517\/14656566.2012.651458","article-title":"Rifaximin for the treatment of irritable bowel syndrome","volume":"13","author":"Cremonini","year":"2012","journal-title":"Expert Opin Pharmacother"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0075","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1038\/ajg.2011.355","article-title":"The efficacy and safety of rifaximin for the irritable bowel syndrome: A systematic review and meta-analysis","volume":"107","author":"Menees","year":"2012","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0080","unstructured":"OCEBM Levels of Evidence Working Group. The Oxford 2011 Levels of Evidence. Oxford Centre for Evidence-Based Medicine. Disponible en: http:\/\/wwwcebmnet\/indexaspx?o=5653"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0085","doi-asserted-by":"crossref","first-page":"2441","DOI":"10.1007\/s10620-010-1276-4","article-title":"Abnormal breath testing in IBS: A meta-analysis","volume":"55","author":"Shah","year":"2010","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0090","first-page":"412","article-title":"Normalization of lactulose breath testing correlates with symptom improvement in irritable bowel syndrome. A double-blind, randomized, placebo-controlled study","volume":"98","author":"Pimentel","year":"2003","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0095","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1136\/ard.2003.011502","article-title":"A link between irritable bowel syndrome and fibromyalgia may be related to findings on lactulose breath testing","volume":"63","author":"Pimentel","year":"2004","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0100","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1111\/j.1572-0241.2005.40795.x","article-title":"Detection of bacterial overgrowth in IBS using the lactulose H2 breath test: Comparison with 14C-D-xylose and healthy controls","volume":"100","author":"Walters","year":"2005","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0105","first-page":"1245","article-title":"Small intestinal bacterial overgrowth in patients with functional gastrointestinal diseases","volume":"135","author":"Madrid","year":"2007","journal-title":"Rev Med Chil"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0110","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1136\/gut.2006.108712","article-title":"Small intestinal bacterial overgrowth in patients with irritable bowel syndrome","volume":"56","author":"Posserud","year":"2007","journal-title":"Gut"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0115","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1111\/j.1365-2982.2008.01142.x","article-title":"Small intestinal bacterial overgrowth in irritable bowel syndrome: Association with colon motility, bowel symptoms, and psychological distress","volume":"20","author":"Grover","year":"2008","journal-title":"Neurogastroenterol Motil"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0120","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1097\/MCG.0b013e3181a099a5","article-title":"Positive glucose breath testing is more prevalent in patients with IBS-like symptoms compared with controls of similar age and gender distribution","volume":"43","author":"Parodi","year":"2009","journal-title":"J Clin Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0125","doi-asserted-by":"crossref","first-page":"2302","DOI":"10.1007\/s10620-009-1010-2","article-title":"Proton pump inhibitor therapy does not affect hydrogen production on lactulose breath test in subjects with IBS","volume":"55","author":"Law","year":"2010","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0130","doi-asserted-by":"crossref","first-page":"242","DOI":"10.4166\/kjg.2010.56.4.242","article-title":"Usefulness of lactulose breath test for the prediction of small intestinal bacterial overgrowth in irritable bowel syndrome","volume":"56","author":"Park","year":"2010","journal-title":"Korean J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0135","doi-asserted-by":"crossref","first-page":"40","DOI":"10.5056\/jnm.2010.16.1.40","article-title":"Frequency of small intestinal bacterial overgrowth in patients with irritable bowel syndrome and chronic non-specific diarrhea","volume":"16","author":"Ghoshal","year":"2010","journal-title":"J Neurogastroenterol Motil"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0140","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1111\/j.1365-2036.2011.04625.x","article-title":"Clinical predictors of small intestinal bacterial overgrowth by duodenal aspirate culture","volume":"33","author":"Choung","year":"2011","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0145","doi-asserted-by":"crossref","first-page":"371","DOI":"10.4103\/1319-3767.87176","article-title":"Small intestinal bacterial overgrowth and lactose intolerance contribute to irritable bowel syndrome symptomatology in Pakistan","volume":"17","author":"Yakoob","year":"2011","journal-title":"Saudi J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0150","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1159\/000336174","article-title":"Comparison of lactulose and glucose breath test for diagnosis of small intestinal bacterial overgrowth in patients with irritable bowel syndrome","volume":"85","author":"Rana","year":"2012","journal-title":"Digestion"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0155","doi-asserted-by":"crossref","first-page":"2700","DOI":"10.1111\/j.1572-0241.2003.08670.x","article-title":"Breath testing to evaluate lactose intolerance in irritable bowel syndrome correlates with lactulose testing and may not reflect true lactose malabsorption","volume":"98","author":"Pimentel","year":"2003","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0160","doi-asserted-by":"crossref","first-page":"6016","DOI":"10.3748\/wjg.13.6016","article-title":"Breath test for differential diagnosis between small intestinal bacterial overgrowth and irritable bowel disease: An observation on non-absorbable antibiotics","volume":"13","author":"Esposito","year":"2007","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0165","doi-asserted-by":"crossref","first-page":"2628","DOI":"10.3748\/wjg.15.2628","article-title":"Small intestine bacterial overgrowth and irritable bowel syndrome-related symptoms: Experience with rifaximin","volume":"15","author":"Peralta","year":"2009","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0170","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/1471-230X-10-23","article-title":"Small intestinal bacterial overgrowth in irritable bowel syndrome: Are there any predictors?","volume":"10","author":"Reddymasu","year":"2010","journal-title":"BMC Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0175","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1136\/gut.2009.205476","article-title":"Combined oro-caecal scintigraphy and lactulose hydrogen breath testing demonstrate that breath testing detects oro-caecal transit, not small intestinal bacterial overgrowth in patients with IBS","volume":"60","author":"Yu","year":"2011","journal-title":"Gut"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0180","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1007\/s10620-012-2033-7","article-title":"The prevalence of overgrowth by aerobic bacteria in the small intestine by small bowel culture: Relationship with irritable bowel syndrome","volume":"57","author":"Pyleris","year":"2012","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0185","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1111\/apt.12087","article-title":"Rifaximin treatment for the irritable bowel syndrome with a positive lactulose hydrogen breath test improves symptoms for at least 3 months","volume":"36","author":"Meyrat","year":"2012","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0190","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.jpeds.2009.03.033","article-title":"Prevalence of small intestinal bacterial overgrowth in children with irritable bowel syndrome: A case-control study","volume":"155","author":"Scarpellini","year":"2009","journal-title":"J Pediatr"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0195","first-page":"185","article-title":"The fecal microbial population in the irritable bowel syndrome","volume":"5","author":"Balsari","year":"1982","journal-title":"Microbiologica"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0200","doi-asserted-by":"crossref","first-page":"1802","DOI":"10.3748\/wjg.v10.i12.1802","article-title":"Intestinal microecology and quality of life in irritable bowel syndrome patients","volume":"10","author":"Si","year":"2004","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0205","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1111\/j.1572-0241.2005.40312.x","article-title":"Analysis of the fecal microbiota of irritable bowel syndrome patients and healthy controls with real-time PCR","volume":"100","author":"Malinen","year":"2005","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0210","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.femsim.2004.08.009","article-title":"Composition and temporal stability of gastrointestinal microbiota in irritable bowel syndrome \u2014 a longitudinal study in IBS and control subjects","volume":"43","author":"Matto","year":"2005","journal-title":"FEMS Immunol Med Microbiol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0215","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1099\/jmm.0.46134-0","article-title":"Prevalence and temporal stability of selected clostridial groups in irritable bowel syndrome in relation to predominant faecal bacteria","volume":"55","author":"Maukonen","year":"2006","journal-title":"J Med Microbiol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0220","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1053\/j.gastro.2007.04.005","article-title":"The fecal microbiota of irritable bowel syndrome patients differs significantly from that of healthy subjects","volume":"133","author":"Kassinen","year":"2007","journal-title":"Gastroenterology"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0225","doi-asserted-by":"crossref","first-page":"2887","DOI":"10.3748\/wjg.15.2887","article-title":"Lower Bifidobacteria counts in both duodenal mucosa-associated and fecal microbiota in irritable bowel syndrome patients","volume":"15","author":"Kerckhoffs","year":"2009","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0230","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1186\/1471-230X-9-95","article-title":"Microbial community analysis reveals high level phylogenetic alterations in the overall gastrointestinal microbiota of diarrhoea-predominant irritable bowel syndrome sufferers","volume":"9","author":"Krogius-Kurikka","year":"2009","journal-title":"BMC Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0235","doi-asserted-by":"crossref","first-page":"5936","DOI":"10.3748\/wjg.15.5936","article-title":"Diarrhoea-predominant irritable bowel syndrome distinguishable by 16S rRNA gene phylotype quantification","volume":"15","author":"Lyra","year":"2009","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0240","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/1757-4749-2-19","article-title":"Luminal and mucosal-associated intestinal microbiota in patients with diarrhea-predominant irritable bowel syndrome","volume":"2","author":"Carroll","year":"2010","journal-title":"Gut Pathog"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0245","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1007\/s10620-009-0934-x","article-title":"A molecular analysis of fecal and mucosal bacterial communities in irritable bowel syndrome","volume":"55","author":"Codling","year":"2010","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0250","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1186\/1471-230X-10-134","article-title":"Ulcerative colitis and irritable bowel patients exhibit distinct abnormalities of the gut microbiota","volume":"10","author":"Noor","year":"2010","journal-title":"BMC Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0255","first-page":"512","article-title":"Altered profiles of intestinal microbiota and organic acids may be the origin of symptoms in irritable bowel syndrome","volume":"22","author":"Tana","year":"2010","journal-title":"Neurogastroenterol Motil"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0260","doi-asserted-by":"crossref","first-page":"G799","DOI":"10.1152\/ajpgi.00154.2011","article-title":"Molecular analysis of the luminal- and mucosal-associated intestinal microbiota in diarrhea-predominant irritable bowel syndrome","volume":"301","author":"Carroll","year":"2011","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0265","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1099\/jmm.0.028126-0","article-title":"Microbial community and metabolomic comparison of irritable bowel syndrome faeces","volume":"60","author":"Ponnusamy","year":"2011","journal-title":"J Med Microbiol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0270","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1053\/j.gastro.2011.07.043","article-title":"Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome","volume":"141","author":"Rajilic-Stojanovic","year":"2011","journal-title":"Gastroenterology"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0275","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/1757-4749-3-6","article-title":"Real-time PCR analysis of enteric pathogens from fecal samples of irritable bowel syndrome subjects","volume":"3","author":"Rinttila","year":"2011","journal-title":"Gut Pathog"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0280","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1053\/j.gastro.2011.06.072","article-title":"Gastrointestinal microbiome signatures of pediatric patients with irritable bowel syndrome","volume":"141","author":"Saulnier","year":"2011","journal-title":"Gastroenterology"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0285","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1111\/j.1365-2982.2012.01891.x","article-title":"Alterations in composition and diversity of the intestinal microbiota in patients with diarrhea-predominant irritable bowel syndrome","volume":"24","author":"Carroll","year":"2012","journal-title":"Neurogastroenterol Motil"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0290","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1111\/j.1365-2036.2012.05007.x","article-title":"Functional dysbiosis within the gut microbiota of patients with constipated-irritable bowel syndrome","volume":"35","author":"Chassard","year":"2012","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0295","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1111\/j.1365-2982.2012.01893.x","article-title":"Increase in fecal primary bile acids and dysbiosis in patients with diarrhea-predominant irritable bowel syndrome","volume":"24","author":"Duboc","year":"2012","journal-title":"Neurogastroenterol Motil"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0300","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1136\/gutjnl-2011-301501","article-title":"An irritable bowel syndrome subtype defined by species-specific alterations in faecal microbiota","volume":"61","author":"Jeffery","year":"2012","journal-title":"Gut"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0305","doi-asserted-by":"crossref","first-page":"406","DOI":"10.4161\/gmic.21009","article-title":"IBS-associated phylogenetic unbalances of the intestinal microbiota are not reverted by probiotic supplementation","volume":"3","author":"Maccaferri","year":"2012","journal-title":"Gut Microbes"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0310","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/j.1365-2982.2011.01803.x","article-title":"Distinct microbial populations exist in the mucosa-associated microbiota of sub-groups of irritable bowel syndrome","volume":"24","author":"Parkes","year":"2012","journal-title":"Neurogastroenterol Motil"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0315","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1099\/jmm.0.022848-0","article-title":"Molecular analysis of faecal and duodenal samples reveals significantly higher prevalence and numbers of Pseudomonas aeruginosa in irritable bowel syndrome","volume":"60","author":"Kerckhoffs","year":"2011","journal-title":"J Med Microbiol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0320","doi-asserted-by":"crossref","first-page":"4532","DOI":"10.3748\/wjg.v16.i36.4532","article-title":"Association of symptoms with gastrointestinal microbiota in irritable bowel syndrome","volume":"16","author":"Malinen","year":"2010","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0325","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1055\/s-0031-1281581","article-title":"Post-infectious irritable bowel syndrome \u2014 a review of the literature","volume":"49","author":"Schwille-Kiuntke","year":"2011","journal-title":"Z Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0330","first-page":"67","article-title":"The incidence and risk factors of post-infectious irritable bowel syndrome: A meta-analysis","volume":"59","author":"Dai","year":"2012","journal-title":"Hepatogastroenterology"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0335","doi-asserted-by":"crossref","first-page":"1650","DOI":"10.1017\/S0950268810000531","article-title":"Disease burden of post-infectious irritable bowel syndrome in The Netherlands","volume":"138","author":"Haagsma","year":"2010","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0340","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1111\/j.1440-1746.2005.03574.x","article-title":"Post-infectious irritable bowel syndrome in patients with Shigella infection","volume":"20","author":"Ji","year":"2005","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0345","doi-asserted-by":"crossref","first-page":"301","DOI":"10.4269\/ajtmh.2010.09-0538","article-title":"Travel and travelers\u2019 diarrhea in patients with irritable bowel syndrome","volume":"82","author":"DuPont","year":"2010","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0350","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1136\/gut.2009.202234","article-title":"Eight year prognosis of postinfectious irritable bowel syndrome following waterborne bacterial dysentery","volume":"59","author":"Marshall","year":"2010","journal-title":"Gut"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0355","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1038\/ajg.2010.74","article-title":"An outbreak of acute bacterial gastroenteritis is associated with an increased incidence of irritable bowel syndrome in children","volume":"105","author":"Thabane","year":"2010","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0360","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1111\/j.1708-8305.2011.00529.x","article-title":"Irritable bowel syndrome among a cohort of European travelers to resource-limited destinations","volume":"18","author":"Pitzurra","year":"2011","journal-title":"J Travel Med"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0365","doi-asserted-by":"crossref","first-page":"ID 343812","DOI":"10.1155\/2012\/343812","article-title":"Irritable bowel syndrome and gastrointestinal parasite infection in a developing nation environment","volume":"2012","author":"Morgan","year":"2012","journal-title":"Gastroenterol Res Pract"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0370","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1136\/gutjnl-2011-300220","article-title":"Irritable bowel syndrome and chronic fatigue 3 years after acute giardiasis: Historic cohort study","volume":"61","author":"Wensaas","year":"2012","journal-title":"Gut"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0375","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1038\/ajg.2012.102","article-title":"Incidence of post-infectious irritable bowel syndrome and functional intestinal disorders following a water-borne viral gastroenteritis outbreak","volume":"107","author":"Zanini","year":"2012","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0380","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1053\/j.gastro.2009.12.049","article-title":"Genetic risk factors for post-infectious irritable bowel syndrome following a waterborne outbreak of gastroenteritis","volume":"138","author":"Villani","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0385","first-page":"300","article-title":"The development of irritable bowel syndrome after Shigella infection: 3 year follow-up study","volume":"47","author":"Kim","year":"2006","journal-title":"Korean J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0390","doi-asserted-by":"crossref","first-page":"3262","DOI":"10.1007\/s10620-011-1762-3","article-title":"Risk of functional gastrointestinal disorders in U.S. military following self-reported diarrhea and vomiting during deployment","volume":"56","author":"Porter","year":"2011","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0395","doi-asserted-by":"crossref","first-page":"872-e699","DOI":"10.1111\/nmo.12204","article-title":"Intestinal recruiting and activation profiles in peripheral blood mononuclear cells in response to pathogen-associated molecular patterns stimulation in patients with IBS","volume":"25","author":"Rodriguez-Fandi\u00f1o","year":"2013","journal-title":"Neurogastroenterol Motil"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0400","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1111\/j.1572-0241.2004.30435.x","article-title":"Post-diarrhea chronic intestinal symptoms and irritable bowel syndrome in North American travelers to Mexico","volume":"99","author":"Okhuysen","year":"2004","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0405","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1097\/01.psy.0000221384.07521.05","article-title":"To \u201clump\u201d or to \u201csplit\u201d the functional somatic syndromes: Can infectious and emotional risk factors differentiate between the onset of chronic fatigue syndrome and irritable bowel syndrome?","volume":"68","author":"Moss-Morris","year":"2006","journal-title":"Psychosom Med"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0410","doi-asserted-by":"crossref","first-page":"e479","DOI":"10.1111\/j.1365-2982.2011.01779.x","article-title":"Postinfectious irritable bowel syndrome: Follow-up of a patient cohort of confirmed cases of bacterial infection with Salmonella or Campylobacter","volume":"23","author":"Schwille-Kiuntke","year":"2011","journal-title":"Neurogastroenterol Motil"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0415","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1111\/j.1572-0241.2007.01084.x","article-title":"Irritable bowel syndrome in persons who acquired trichinellosis","volume":"102","author":"Soyturk","year":"2007","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0420","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.cgh.2007.01.007","article-title":"Gastrointestinal symptoms after infectious diarrhea: A five-year follow-up in a Swedish cohort of adults","volume":"5","author":"Tornblom","year":"2007","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0425","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.cgh.2006.11.025","article-title":"Postinfectious irritable bowel syndrome after a food-borne outbreak of acute gastroenteritis attributed to a viral pathogen","volume":"5","author":"Marshall","year":"2007","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0430","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1111\/j.1365-2036.2007.03399.x","article-title":"Systematic review and meta-analysis: The incidence and prognosis of post-infectious irritable bowel syndrome","volume":"26","author":"Thabane","year":"2007","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0435","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1053\/j.gastro.2006.05.053","article-title":"Incidence and epidemiology of irritable bowel syndrome after a large waterborne outbreak of bacterial dysentery","volume":"131","author":"Marshall","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0440","doi-asserted-by":"crossref","first-page":"S42","DOI":"10.1038\/ki.2008.618","article-title":"Post-infectious irritable bowel syndrome following water contamination","volume":"112","author":"Marshall","year":"2009","journal-title":"Kidney Int Suppl"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0445","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1111\/apt.12080","article-title":"Review article: Associations between immune activation, intestinal permeability and the irritable bowel syndrome","volume":"36","author":"Matricon","year":"2012","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0450","first-page":"637","article-title":"Irritable bowel syndrome immune hypothesis. Part one: The role of lymphocytes and mast cells","volume":"102","author":"Ortiz-Lucas","year":"2010","journal-title":"Rev Esp Enferm Dig"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0455","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1136\/gut.2010.213108","article-title":"The mast cell stabiliser ketotifen decreases visceral hypersensitivity and improves intestinal symptoms in patients with irritable bowel syndrome","volume":"59","author":"Klooker","year":"2010","journal-title":"Gut"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0460","doi-asserted-by":"crossref","first-page":"619","DOI":"10.3109\/00365521.2012.666672","article-title":"Subclinical mucosal inflammation in diarrhea-predominant irritable bowel syndrome (IBS) in a tropical setting","volume":"47","author":"De Silva","year":"2012","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0465","doi-asserted-by":"crossref","first-page":"1590","DOI":"10.1007\/BF01303164","article-title":"Terminal ileal mucosal mast cells in irritable bowel syndrome","volume":"38","author":"Weston","year":"1993","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0470","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1136\/gut.44.3.400","article-title":"The role of psychological and biological factors in postinfective gut dysfunction","volume":"44","author":"Gwee","year":"1999","journal-title":"Gut"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0475","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1136\/gut.47.6.804","article-title":"Increased rectal mucosal enteroendocrine cells, T lymphocytes, and increased gut permeability following acute Campylobacter enteritis and in post-dysenteric irritable bowel syndrome","volume":"47","author":"Spiller","year":"2000","journal-title":"Gut"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0480","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1046\/j.1365-2982.2000.00221.x","article-title":"Increased mast cells in the irritable bowel syndrome","volume":"12","author":"O'Sullivan","year":"2000","journal-title":"Neurogastroenterol Motil"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0485","doi-asserted-by":"crossref","first-page":"1972","DOI":"10.1053\/gast.2002.37059","article-title":"Full-thickness biopsy of the jejunum reveals inflammation and enteric neuropathy in irritable bowel syndrome","volume":"123","author":"Tornblom","year":"2002","journal-title":"Gastroenterology"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0490","doi-asserted-by":"crossref","first-page":"204","DOI":"10.3346\/jkms.2003.18.2.204","article-title":"Activated mast cells infiltrate in close proximity to enteric nerves in diarrhea-predominant irritable bowel syndrome","volume":"18","author":"Park","year":"2003","journal-title":"J Korean Med Sci"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0495","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1053\/j.gastro.2003.09.028","article-title":"Relative importance of enterochromaffin cell hyperplasia, anxiety, and depression in postinfectious IBS","volume":"125","author":"Dunlop","year":"2003","journal-title":"Gastroenterology"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0500","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1111\/j.1572-0241.2003.07542.x","article-title":"Distinctive clinical, psychological, and histological features of postinfective irritable bowel syndrome","volume":"98","author":"Dunlop","year":"2003","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0505","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1053\/j.gastro.2003.11.055","article-title":"Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome","volume":"126","author":"Barbara","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0510","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1016\/S1542-3565(05)00410-6","article-title":"A controlled study of colonic immune activity and beta7+ blood T lymphocytes in patients with irritable bowel syndrome","volume":"3","author":"Ohman","year":"2005","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0515","doi-asserted-by":"crossref","first-page":"163","DOI":"10.14712\/18059694.2018.46","article-title":"Mucosal mast cells in irritable bowel syndrome and inflammatory bowel disease","volume":"48","author":"Tunc","year":"2005","journal-title":"Acta Medica (Hradec Kralove)"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0520","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1111\/j.1440-1746.2005.04143.x","article-title":"Mucosal mast cell counts correlate with visceral hypersensitivity in patients with diarrhea predominant irritable bowel syndrome","volume":"21","author":"Park","year":"2006","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0525","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1136\/gut.2006.100594","article-title":"Diarrhoea-predominant IBS patients show mast cell activation and hyperplasia in the jejunum","volume":"56","author":"Guilarte","year":"2007","journal-title":"Gut"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0530","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1136\/gut.2003.021154","article-title":"Bacillary dysentery as a causative factor of irritable bowel syndrome and its pathogenesis","volume":"53","author":"Wang","year":"2004","journal-title":"Gut"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0535","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1136\/gut.2007.127068","article-title":"Mast cells and cellularity of the colonic mucosa correlated with fatigue and depression in irritable bowel syndrome","volume":"57","author":"Piche","year":"2008","journal-title":"Gut"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0540","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1111\/j.1440-1746.2008.05574.x","article-title":"The alteration of enterochromaffin cell, mast cell, and lamina propria T lymphocyte numbers in irritable bowel syndrome and its relationship with psychological factors","volume":"23","author":"Lee","year":"2008","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0545","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1111\/j.1365-2036.2009.03937.x","article-title":"Duodenal mastocytosis, eosinophilia and intraepithelial lymphocytosis as possible disease markers in the irritable bowel syndrome and functional dyspepsia","volume":"29","author":"Walker","year":"2009","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0550","first-page":"275","article-title":"Histopathological alterations in post-infectious irritable bowel syndrome in Bangladeshi population","volume":"19","author":"Bhuiyan","year":"2010","journal-title":"Mymensingh Med J"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0555","doi-asserted-by":"crossref","first-page":"45","DOI":"10.3349\/ymj.2010.51.1.45","article-title":"Increased immunoendocrine cells in intestinal mucosa of postinfectious irritable bowel syndrome patients 3 years after acute Shigella infection \u2014 an observation in a small case control study","volume":"51","author":"Kim","year":"2010","journal-title":"Yonsei Med J"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0560","first-page":"751","article-title":"Mast cells count and serum cytokine levels in patients with irritable bowel syndrome","volume":"57","author":"Goral","year":"2010","journal-title":"Hepatogastroenterology"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0565","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1038\/ajg.2008.94","article-title":"Mucosal immune activation in irritable bowel syndrome: Gender-dependence and association with digestive symptoms","volume":"104","author":"Cremon","year":"2009","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0570","first-page":"315","article-title":"Increase of intraepithelial lymphocytes in patients with irritable bowel syndrome","volume":"31","author":"Arevalo","year":"2011","journal-title":"Rev Gastroenterol Peru"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0575","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1038\/ajg.2012.54","article-title":"Mucosal immune cell numbers and visceral sensitivity in patients with irritable bowel syndrome: is there any relationship?","volume":"107","author":"Braak","year":"2012","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0580","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1038\/ajg.2011.423","article-title":"Serum and colonic mucosal immune markers in irritable bowel syndrome","volume":"107","author":"Chang","year":"2012","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0585","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1053\/gast.2002.33579","article-title":"Activation of the mucosal immune system in irritable bowel syndrome","volume":"122","author":"Chadwick","year":"2002","journal-title":"Gastroenterology"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0590","first-page":"847","article-title":"Morphometric study of colonic biopsies: A new method of estimating inflammatory diseases","volume":"60","author":"Salzmann","year":"1989","journal-title":"Lab Invest"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0595","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1136\/gut.42.1.42","article-title":"Postprandial plasma 5-hydroxytryptamine in diarrhoea predominant irritable bowel syndrome: A pilot study","volume":"42","author":"Bearcroft","year":"1998","journal-title":"Gut"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0600","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1136\/gut.52.5.663","article-title":"Increased platelet depleted plasma 5-hydroxytryptamine concentration following meal ingestion in symptomatic female subjects with diarrhoea predominant irritable bowel syndrome","volume":"52","author":"Houghton","year":"2003","journal-title":"Gut"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0605","doi-asserted-by":"crossref","first-page":"2639","DOI":"10.1023\/A:1021039032413","article-title":"Lower frequency of MMC is found in IBS subjects with abnormal lactulose breath test, suggesting bacterial overgrowth","volume":"47","author":"Pimentel","year":"2002","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0610","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1023\/A:1021738515885","article-title":"Methane production during lactulose breath test is associated with gastrointestinal disease presentation","volume":"48","author":"Pimentel","year":"2003","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0615","doi-asserted-by":"crossref","first-page":"G1089","DOI":"10.1152\/ajpgi.00574.2004","article-title":"Methane, a gas produced by enteric bacteria, slows intestinal transit and augments small intestinal contractile activity","volume":"290","author":"Pimentel","year":"2006","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0620","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1007\/s10620-011-1590-5","article-title":"Methane on breath testing is associated with constipation: A systematic review and meta-analysis","volume":"56","author":"Kunkel","year":"2011","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0625","first-page":"157","article-title":"Reassessment of the role of methane production between irritable bowel syndrome and functional constipation","volume":"21","author":"Furnari","year":"2012","journal-title":"J Gastrointestin Liver Dis"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0630","doi-asserted-by":"crossref","first-page":"174","DOI":"10.5009\/gnl.2009.3.3.174","article-title":"The relationship between small-intestinal bacterial overgrowth and intestinal permeability in patients with irritable bowel syndrome","volume":"3","author":"Park","year":"2009","journal-title":"Gut Liver"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0635","doi-asserted-by":"crossref","first-page":"49","DOI":"10.5114\/aoms.2010.13507","article-title":"The place of antibiotics in management of irritable bowel syndrome: A systematic review and meta-analysis","volume":"6","author":"Rezaie","year":"2010","journal-title":"Arch Med Sci"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0645","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1345\/aph.1K345","article-title":"Rifaximin treatment for symptoms of irritable bowel syndrome","volume":"42","author":"Fumi","year":"2008","journal-title":"Ann Pharmacother"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0650","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1111\/j.1365-2036.2011.04637.x","article-title":"Review article: The treatment of functional abdominal bloating and distension","volume":"33","author":"Schmulson","year":"2011","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0655","doi-asserted-by":"crossref","first-page":"82","DOI":"10.4166\/kjg.2011.57.2.82","article-title":"Guidelines for the treatment of irritable bowel syndrome","volume":"57","author":"Kwon","year":"2011","journal-title":"Korean J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0660","doi-asserted-by":"crossref","first-page":"557","DOI":"10.7326\/0003-4819-145-8-200610170-00004","article-title":"The effect of a nonabsorbed oral antibiotic (rifaximin) on the symptoms of the irritable bowel syndrome: A randomized trial","volume":"145","author":"Pimentel","year":"2006","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0665","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1111\/j.1572-0241.2006.00458.x","article-title":"A randomized double-blind placebo-controlled trial of rifaximin in patients with abdominal bloating and flatulence","volume":"101","author":"Sharara","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0670","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1111\/j.1365-2036.2007.03259.x","article-title":"High dosage rifaximin for the treatment of small intestinal bacterial overgrowth","volume":"25","author":"Scarpellini","year":"2007","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0675","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1056\/NEJMoa1004409","article-title":"Rifaximin therapy for patients with irritable bowel syndrome without constipation","volume":"364","author":"Pimentel","year":"2011","journal-title":"N Engl J Med"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0680","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1097\/MPG.0b013e3181effa3b","article-title":"Double-blind, placebo-controlled antibiotic treatment study of small intestinal bacterial overgrowth in children with chronic abdominal pain","volume":"52","author":"Collins","year":"2011","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0685","first-page":"89","article-title":"Small intestine bacterial overgrowth in irritable bowel syndrome: a retrospective study with rifaximin","volume":"52","author":"Cuoco","year":"2006","journal-title":"Minerva Gastroenterol Dietol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0690","first-page":"139","article-title":"Results of small intestinal bacterial overgrowth testing in irritable bowel syndrome patients: Clinical profiles and effects of antibiotic trial","volume":"52","author":"Majewski","year":"2007","journal-title":"Adv Med Sci"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0695","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1007\/s10620-006-9104-6","article-title":"Neomycin improves constipation-predominant irritable bowel syndrome in a fashion that is dependent on the presence of methane gas: Subanalysis of a double-blind randomized controlled study","volume":"51","author":"Pimentel","year":"2006","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0700","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.3109\/00365520903274401","article-title":"Antibiotic or bacterial therapy in post-giardiasis irritable bowel syndrome","volume":"44","author":"Morken","year":"2009","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0705","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1007\/s10620-007-0021-0","article-title":"Restless legs syndrome in patients with irritable bowel syndrome: Response to small intestinal bacterial overgrowth therapy","volume":"53","author":"Weinstock","year":"2008","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0710","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/s10620-007-9839-8","article-title":"Rifaximin versus other antibiotics in the primary treatment and retreatment of bacterial overgrowth in IBS","volume":"53","author":"Yang","year":"2008","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0715","first-page":"435","article-title":"Low-dose nocturnal tegaserod or erythromycin delays symptom recurrence after treatment of irritable bowel syndrome based on presumed bacterial overgrowth","volume":"5","author":"Pimentel","year":"2009","journal-title":"Gastroenterol Hepatol (N Y)"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0720","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.1007\/s10620-011-1728-5","article-title":"Effects of rifaximin treatment and retreatment in nonconstipated IBS subjects","volume":"56","author":"Pimentel","year":"2011","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0725","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1517\/13543780902780175","article-title":"Review of rifaximin as treatment for SIBO and IBS","volume":"18","author":"Pimentel","year":"2009","journal-title":"Expert Opin Investig Drugs"},{"issue":"Suppl 1","key":"10.1016\/j.rgmx.2014.01.004_bib0730","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1159\/000081990","article-title":"Rifaximin, a poorly absorbed antibiotic: Pharmacology and clinical potential","volume":"51","author":"Scarpignato","year":"2005","journal-title":"Chemotherapy"},{"issue":"Suppl 1","key":"10.1016\/j.rgmx.2014.01.004_bib0735","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1159\/000081991","article-title":"Rifaximin: In vitro and in vivo antibacterial activity \u2014 a review","volume":"51","author":"Jiang","year":"2005","journal-title":"Chemotherapy"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0740","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1586\/14787210.3.2.201","article-title":"Rifaximin: A nonabsorbable rifamycin antibiotic for use in nonsystemic gastrointestinal infections","volume":"3","author":"Gerard","year":"2005","journal-title":"Expert Rev Anti Infect Ther"},{"key":"10.1016\/j.rgmx.2014.01.004_bib0745","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1179\/joc.2008.20.2.186","article-title":"Effects of rifaximin on bacterial virulence mechanisms at supra- and sub-inhibitory concentrations","volume":"20","author":"Debbia","year":"2008","journal-title":"J Chemother"}],"container-title":["Revista de Gastroenterolog\u00eda de M\u00e9xico"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0375090614000317?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0375090614000317?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,10]],"date-time":"2019-08-10T15:30:15Z","timestamp":1565451015000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0375090614000317"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4]]},"references-count":148,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["S0375090614000317"],"URL":"https:\/\/doi.org\/10.1016\/j.rgmx.2014.01.004","relation":{},"ISSN":["0375-0906"],"issn-type":[{"value":"0375-0906","type":"print"}],"subject":[],"published":{"date-parts":[[2014,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Microbiota, infecciones gastrointestinales, inflamaci\u00f3n de bajo grado y antibioticoterapia en el s\u00edndrome de intestino irritable. Una revisi\u00f3n basada en evidencias","name":"articletitle","label":"Article Title"},{"value":"Revista de Gastroenterolog\u00eda de M\u00e9xico","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rgmx.2014.01.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Asociaci\u00f3n Mexicana de Gastroenterolog\u00eda. Published by Masson Doyma M\u00e9xico S.A.","name":"copyright","label":"Copyright"}]}}