{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T08:57:06Z","timestamp":1762419426813,"version":"build-2065373602"},"reference-count":43,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,11,24]],"date-time":"2021-11-24T00:00:00Z","timestamp":1637712000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revista de Gastroenterolog\u00eda de M\u00e9xico (English Edition)"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1016\/j.rgmxen.2021.11.015","type":"journal-article","created":{"date-parts":[[2021,12,6]],"date-time":"2021-12-06T09:33:33Z","timestamp":1638783213000},"page":"12-18","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["A descriptive study of inflammatory bowel disease at an Egyptian tertiary care center"],"prefix":"10.1016","volume":"88","author":[{"given":"K.A.","family":"El-Atrebi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Taher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.H.","family":"El Aguizy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.M.","family":"Ali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Hegazy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.M.","family":"El-Sayed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Eysa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.A.","family":"El-Atreby","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.A.","family":"Mohammed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.T.","family":"El-Bassyouni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.rgmxen.2021.11.015_bib0005","doi-asserted-by":"crossref","first-page":"S14","DOI":"10.1053\/j.gastro.2019.01.066","article-title":"Meta-analysis of dietary intervention effects in Crohn\u2019s disease and ulcerative colitis","volume":"156","author":"DuBois","year":"2019","journal-title":"Gastroenterology"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0010","first-page":"79","article-title":"Ulcerative colitis: a case in Togo","volume":"22","author":"Agoda-Koussema","year":"2012","journal-title":"Med Sante Trop"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0015","doi-asserted-by":"crossref","first-page":"814","DOI":"10.3748\/wjg.v20.i3.814","article-title":"Epidemiological and clinical characteristics of inflammatory bowel diseases in Cairo, Egypt","volume":"20","author":"Esmat","year":"2014","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0020","first-page":"1","article-title":"Inflammatory bowel disease (IBD) unit: an Egyptian experience","volume":"5","author":"El-Atrebi","year":"2018","journal-title":"Gastroenterol Dig Syst"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0025","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1053\/j.gastro.2019.01.002","article-title":"Past and future burden of inflammatory bowel diseases based on modeling of population-based data","volume":"156","author":"Coward","year":"2019","journal-title":"Gastroenterology"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0030","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1038\/nature10209","article-title":"Genetics and pathogenesis of inflammatory bowel disease","volume":"474","author":"Khor","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0035","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1038\/nrgastro.2015.34","article-title":"Epidemiology and risk factors for IBD","volume":"12","author":"Ananthakrishnan","year":"2015","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0040","doi-asserted-by":"crossref","first-page":"6296","DOI":"10.3748\/wjg.v22.i27.6296","article-title":"Environmental risk factors for inflammatory bowel diseases: evidence based literature review","volume":"22","author":"Abegunde","year":"2016","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0045","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1056\/NEJM198712243172603","article-title":"Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study","volume":"317","author":"Schroeder","year":"1987","journal-title":"N Engl J Med"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0050","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1136\/gut.2005.088732","article-title":"Mucosal healing in inflammatory bowel disease: impossible ideal or therapeutic target?","volume":"56","author":"Rutgeerts","year":"2007","journal-title":"Gut"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0055","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/S0016-5085(76)80163-1","article-title":"Development of a Crohn\u2019s disease activity index. National Cooperative Crohn\u2019s Disease Study","volume":"70","author":"Best","year":"1976","journal-title":"Gastroenterology"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0060","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1093\/gastro\/gou031","article-title":"Histological evaluation in ulcerative colitis","volume":"2","author":"DeRoche","year":"2014","journal-title":"Gastroenterol Rep (Oxf)"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0065","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/S0140-6736(15)00465-1","article-title":"Inherited determinants of Crohn\u2019s disease and ulcerative colitis phenotypes: a genetic association study","volume":"387","author":"Cleynen","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0070","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD002913.pub2","article-title":"Budesonide for maintenance of remission in Crohn\u2019s disease","volume":"1","author":"Benchimol","year":"2009","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0075","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1053\/j.gastro.2011.10.001","article-title":"Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review","volume":"142","author":"Molodecky","year":"2012","journal-title":"Gastroenterology"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0080","doi-asserted-by":"crossref","first-page":"34","DOI":"10.5223\/pghn.2018.21.1.34","article-title":"Higher morbidity of monogenic inflammatory bowel disease compared to the adolescent onset inflammatory bowel disease","volume":"21","author":"Kim","year":"2018","journal-title":"Pediatr Gastroenterol Hepatol Nutr"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0085","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s12889-019-6858-2","article-title":"A four-decade analysis of the incidence trends, sociodemographic and clinical characteristics of inflammatory bowel disease patients at single tertiary Centre, Kuala Lumpur, Malaysia","volume":"19","author":"Mokhtar","year":"2019","journal-title":"BMC Public Health"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0090","first-page":"140","article-title":"Epidemiology of inflammatory bowel diseases in Iran and Asia; a mini review","volume":"38","author":"Safarpour","year":"2013","journal-title":"Iran J Med Sci"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0095","first-page":"10","article-title":"The epidemiology and phenotype of Crohn\u2019s disease in the Chinese population","volume":"646","author":"Leong","year":"2004","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0100","doi-asserted-by":"crossref","first-page":"S85","DOI":"10.1007\/BF02237231","article-title":"Crohn\u2019s disease in Japan: diagnostic criteria and epidemiology","volume":"43","author":"Yao","year":"2000","journal-title":"Dis Colon Rectum"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0105","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1002\/ibd.20310","article-title":"Epidemiology of inflammatory bowel disease in the Songpa-Kangdong district, Seoul, Korea, 1986-2005: a KASID study","volume":"14","author":"Yang","year":"2010","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0110","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.3748\/wjg.v10.i9.1341","article-title":"Epidemiology and outcome of Crohn\u2019s disease in a teaching hospital in Riyadh","volume":"10","author":"Al-Ghamdi","year":"2004","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0115","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1080\/10408398.2012.760515","article-title":"The impact of dietary interventions on the symptoms of inflammatory bowel disease: a systematic review","volume":"56","author":"Charlebois","year":"2016","journal-title":"Crit Rev Food Sci Nutr"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0120","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/j.dld.2019.01.024","article-title":"Impact of inflammatory bowel diseases on working life: a French nationwide survey","volume":"51","author":"Le Berre","year":"2019","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0125","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1007\/s00535-009-0057-3","article-title":"Prevalence of ulcerative colitis and Crohn\u2019s disease in Japan","volume":"44","author":"Asakura","year":"2009","journal-title":"J Gastroenterol"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0130","first-page":"1","article-title":"Emerging epidemic of inflammatory bowel disease in a middle-income country: a nation-wide study from Iran","volume":"19","author":"Malekzadeh","year":"2016","journal-title":"Arch Iran Med"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0135","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1093\/gastro\/gou028","article-title":"Colonoscopic evaluation in ulcerative colitis","volume":"2","author":"Paine","year":"2014","journal-title":"Gastroenterol Rep (Oxf)"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0140","series-title":"Inflammatory bowel disease","first-page":"299","article-title":"Clinical features, course, laboratory findings, and complications in ulcerative colitis","author":"Miner","year":"2000"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0145","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1177\/1756283X10361304","article-title":"Current trends in inflammatory bowel disease: the natural history","volume":"3","author":"Langholz","year":"2010","journal-title":"Therap Adv Gastroenterol"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0150","doi-asserted-by":"crossref","first-page":"21","DOI":"10.3748\/wjg.v21.i1.21","article-title":"Differential diagnosis in inflammatory bowel disease colitis: state of the art and future perspectives","volume":"21","author":"Tontini","year":"2015","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0155","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/4869718","article-title":"Vitamin D deficiency is associated with endoscopic severity in patients with Crohn\u2019s disease","volume":"2017","author":"Ye","year":"2017","journal-title":"Gastroenterol Res Pract"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0160","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1136\/gut.2010.227884","article-title":"Impact of azathioprine and tumor necrosis factor antagonists on the need for surgery in newly diagnosed Crohn\u2019s disease","volume":"60","author":"Peyrin-Biroulet","year":"2011","journal-title":"Gut"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0165","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.crohns.2013.08.009","article-title":"Incidence and clinical course of Crohn\u2019s disease during the first year \u2014 results from the IBD Cohort of the Uppsala Region (ICURE) of Sweden 2005-2009","volume":"8","author":"Sj\u00f6berg","year":"2014","journal-title":"J Crohns Colitis"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0170","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/s12876-019-0963-7","article-title":"Presenting symptoms in inflammatory bowel disease: descriptive analysis of a community-based inception cohort","volume":"19","author":"Perler","year":"2019","journal-title":"BMC Gastroenterol"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0175","doi-asserted-by":"crossref","DOI":"10.1080\/21688370.2018.1463897","article-title":"Pathophysiology of IBD associated diarrhea","volume":"6","author":"Anbazhagan","year":"2018","journal-title":"Tissue Barriers"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0180","first-page":"53","article-title":"The use of fecal calprotectin in monitoring activity of inflammatory bowel diseases","volume":"91","author":"Knyazev","year":"2019","journal-title":"Ter Arkh"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0185","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1093\/ecco-jcc\/jjy222.686","article-title":"P562 Treatment of older inflammatory bowel disease patients; steroid use and escalation to steroid sparing therapy","volume":"13","author":"Asscher","year":"2019","journal-title":"J Crohns Colitis"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0190","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1016\/j.clinthera.2018.07.013","article-title":"Treatment patterns and sequencing in patients with inflammatory bowel disease","volume":"40","author":"Brady","year":"2018","journal-title":"Clin Ther"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0195","doi-asserted-by":"crossref","first-page":"2162","DOI":"10.1016\/j.jpedsurg.2019.01.006","article-title":"Anti-TNF biologic therapy does not increase postoperative morbidity in pediatric Crohn\u2019s patients","volume":"54","author":"Lightner","year":"2019","journal-title":"Pediatr Surg"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0200","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s11894-019-0698-1","article-title":"Extraintestinal manifestations of inflammatory bowel disease: epidemiology, etiopathogenesis, and management","volume":"21","author":"Garber","year":"2019","journal-title":"Curr Gastroenterol Rep"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0205","first-page":"4","article-title":"Extraintestinal manifestations of inflammatory bowel disease: clinical aspects and pathogenesis","volume":"3","author":"Ferreira","year":"2018","journal-title":"J Gastroenterol Dig Dis"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0210","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.1097\/MIB.0000000000000429","article-title":"Chronological order of appearance of extraintestinal manifestations relative to the time of IBD diagnosis in the Swiss inflammatory bowel disease cohort","volume":"21","author":"Vavricka","year":"2015","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.rgmxen.2021.11.015_bib0215","article-title":"Prevalence of extraintestinal manifestations in Korean inflammatory bowel disease patients","volume":"13","author":"Yang","year":"2018","journal-title":"PLoS One"}],"container-title":["Revista de Gastroenterolog\u00eda de M\u00e9xico (English Edition)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2255534X21001316?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2255534X21001316?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T08:53:02Z","timestamp":1762419182000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2255534X21001316"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":43,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["S2255534X21001316"],"URL":"https:\/\/doi.org\/10.1016\/j.rgmxen.2021.11.015","relation":{},"ISSN":["2255-534X"],"issn-type":[{"type":"print","value":"2255-534X"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A descriptive study of inflammatory bowel disease at an Egyptian tertiary care center","name":"articletitle","label":"Article Title"},{"value":"Revista de Gastroenterolog\u00eda de M\u00e9xico (English Edition)","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rgmxen.2021.11.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.rgmx.2021.03.004","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Published by Masson Doyma M\u00e9xico S.A. on behalf of Asociaci\u00f3n Mexicana de Gastroenterolog\u00eda.","name":"copyright","label":"Copyright"}]}}