{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:47:07Z","timestamp":1787845627304,"version":"build-2784847793"},"reference-count":157,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,4]],"date-time":"2024-04-04T00:00:00Z","timestamp":1712188800000},"content-version":"vor","delay-in-days":94,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revista de Gastroenterolog\u00eda de M\u00e9xico (English Edition)"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1016\/j.rgmxen.2023.08.008","type":"journal-article","created":{"date-parts":[[2024,4,9]],"date-time":"2024-04-09T16:08:55Z","timestamp":1712678935000},"page":"144-162","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Guidelines for the management of coagulation disorders in patients with cirrhosis"],"prefix":"10.1016","volume":"89","author":[{"given":"I.","family":"Aiza-Haddad","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.E.","family":"Cisneros-Garza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Morales-Guti\u00e9rrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Mal\u00e9-Vel\u00e1zquez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.T.","family":"Rizo-Robles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Alvarado-Reyes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.A.","family":"Barrientos-Quintanilla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Betancourt-S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Cerda-Reyes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Contreras-Oma\u00f1a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.B.","family":"Dehesa-Violante","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.C.","family":"Flores-Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"G\u00f3mez-Almaguer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.F.","family":"Higuera-de la Tijera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.A.","family":"Lira-Pedrin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.E.","family":"Lira-Vera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Manzano-Cort\u00e9s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.E.","family":"Mel\u00e9ndez-Mena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.R.","family":"Mu\u00f1oz-Ram\u00edrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.L.","family":"P\u00e9rez-Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.V.","family":"Ramos-G\u00f3mez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.F.","family":"S\u00e1nchez-\u00c1vila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.rgmxen.2023.08.008_bib0005","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1056\/NEJMra1011170","article-title":"The coagulopathy of chronic liver disease","volume":"365","author":"Tripodi","year":"2011","journal-title":"N Engl J Med."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0010","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1002\/hep.21231","article-title":"Elevated levels of von Willebrand factor in cirrhosis support platelet adhesion despite reduced functional capacity","volume":"44","author":"Lisman","year":"2006","journal-title":"Hepatology."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0015","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1002\/hep.20569","article-title":"Evidence of normal thrombin generation in cirrhosis despite abnormal conventional coagulation tests","volume":"41","author":"Tripodi","year":"2005","journal-title":"Hepatology."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0020","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1016\/j.cgh.2009.04.019","article-title":"A prospective study of conventional and expanded coagulation indices in predicting ulcer bleeding after variceal band ligation","volume":"7","author":"Vieira-da Rocha","year":"2009","journal-title":"Clin Gastroenterol Hepatol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0025","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1002\/hep.28628","article-title":"Coagulation parameters and major bleeding in critically ill patients with cirrhosis","volume":"64","author":"Drolz","year":"2016","journal-title":"Hepatology."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0030","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/j.cgh.2010.06.018","article-title":"Incidence of bleeding following invasive procedures in patients with thrombocytopenia and advanced liver disease","volume":"8","author":"Giannini","year":"2010","journal-title":"Clin Gastroenterol Hepatol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0035","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1111\/jth.15239","article-title":"The concept of rebalanced hemostasis in patients with liver disease: Communication from the ISTH SSC working group on hemostatic management of patients with liver disease","volume":"19","author":"Lisman","year":"2021","journal-title":"J Thromb Haemost."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0040","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1002\/rth2.12028","article-title":"Pathogenesis, prevention, and management of bleeding and thrombosis in patients with liver diseases","volume":"1","author":"Lisman","year":"2017","journal-title":"Res Pract Thromb Haemost."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0045","first-page":"39","article-title":"The pathophysiology of thrombocytopenia in chronic liver disease","volume":"8","author":"Mitchell","year":"2016","journal-title":"Hepatic Med Evid Res."},{"issue":"Suppl D","key":"10.1016\/j.rgmxen.2023.08.008_bib0050","first-page":"60D","article-title":"Thrombocytopenia in liver disease","volume":"14","author":"Peck-Radosavljevic","year":"2000","journal-title":"Can J Gastroenterol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0055","doi-asserted-by":"crossref","first-page":"2516","DOI":"10.1111\/j.1572-0241.2003.08665.x","article-title":"Relationship between thrombopoietin serum levels and liver function in patients with chronic liver disease related to hepatitis C virus infection","volume":"98","author":"Giannini","year":"2003","journal-title":"Am J Gastroenterol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0060","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.1111\/j.1572-0241.1999.01231.x","article-title":"Serum thrombopoietin levels in patients with chronic hepatitis and liver cirrhosis","volume":"94","author":"Kawasaki","year":"1999","journal-title":"Am J Gastroenterol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0065","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1046\/j.1440-1746.2003.03026.x","article-title":"Role of elevated platelet-associated immunoglobulin G and hypersplenism in thrombocytopenia of chronic liver diseases","volume":"18","author":"Sanjo","year":"2003","journal-title":"J Gastroenterol Hepatol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0070","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/2052-0492-1-9","article-title":"Thrombocytopenia in adult patients with sepsis: Incidence, risk factors, and its association with clinical outcome","volume":"1","author":"Venkata","year":"2013","journal-title":"J Intensive Care."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0075","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/S1665-2681(19)31312-2","article-title":"Coagulation abnormalities in the cirrhotic patient","volume":"12","author":"Muci\u00f1o-Bermejo","year":"2013","journal-title":"Ann Hepatol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0080","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1053\/j.gastro.2019.03.070","article-title":"AGA clinical practice update: coagulation in cirrhosis","volume":"157","author":"O\u2019Leary","year":"2019","journal-title":"Gastroenterology."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0085","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1038\/ajg.2016.498","article-title":"Changing concepts of cirrhotic coagulopathy","volume":"112","author":"Tripodi","year":"2017","journal-title":"Am J Gastroenterol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0090","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1097\/MOH.0000000000000164","article-title":"Hemostasis abnormalities in cirrhosis","volume":"22","author":"Tripodi","year":"2015","journal-title":"Curr Opin Hematol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0095","doi-asserted-by":"crossref","first-page":"G171","DOI":"10.1152\/ajpgi.00402.2017","article-title":"Role of the blood coagulation cascade in hepatic fibrosis","volume":"315","author":"Pant","year":"2018","journal-title":"Am J Physiol Gastrointest Liver Physiol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0100","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1055\/s-2002-23205","article-title":"Coagulation disorders in liver disease","volume":"22","author":"Amitrano","year":"2002","journal-title":"Semin Liver Dis."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0105","doi-asserted-by":"crossref","first-page":"11","DOI":"10.5482\/HAMO-14-11-0075","article-title":"Endothelium and haemostasis","volume":"35","author":"Aird","year":"2015","journal-title":"Hamostaseologie."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0110","doi-asserted-by":"crossref","first-page":"160","DOI":"10.2337\/diacare.14.2.160","article-title":"Endothelium and regulation of coagulation","volume":"14","author":"Stern","year":"1991","journal-title":"Diabetes Care."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0115","doi-asserted-by":"crossref","first-page":"863","DOI":"10.5811\/westjem.2018.7.37893","article-title":"The misunderstood coagulopathy of liver disease: a review for the acute setting","volume":"19","author":"Harrison","year":"2018","journal-title":"West J Emerg Med."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0120","doi-asserted-by":"crossref","first-page":"100120","DOI":"10.1016\/j.jhepr.2020.100120","article-title":"Biomarkers of liver dysfunction correlate with a prothrombotic and not with a prohaemorrhagic profile in patients with cirrhosis","volume":"2","author":"Zermatten","year":"2020","journal-title":"JHEP Rep."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0125","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1038\/ajg.2017.457","article-title":"Platelet count does not predict bleeding in cirrhotic patients: Results from the PRO-LIVER Study","volume":"113","author":"Basili","year":"2018","journal-title":"Am J Gastroenterol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0130","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.ejim.2016.11.007","article-title":"Bleeding after invasive procedures is rare and unpredicted by platelet counts in cirrhotic patients with thrombocytopenia","volume":"38","author":"Napolitano","year":"2017","journal-title":"Eur J Intern Med."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0135","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1002\/hep.31646","article-title":"Vascular liver disorders, portal vein thrombosis, and procedural bleeding in patients with liver disease: 2020 Practice Guidance by the American Association for the Study of Liver Diseases","volume":"73","author":"Northup","year":"2021","journal-title":"Hepatology."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0140","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/s11894-017-0585-6","article-title":"Bleeding risk with invasive procedures in patients with cirrhosis and coagulopathy","volume":"19","author":"Zakeri","year":"2017","journal-title":"Curr Gastroenterol Rep."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0145","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/s12664-015-0584-1","article-title":"Coagulopathy in cirrhosis: a prospective study to correlate conventional tests of coagulation and bleeding following invasive procedures in cirrhotics","volume":"34","author":"Shah","year":"2015","journal-title":"Indian J Gastroenterol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0150","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.23736\/S0375-9393.19.13687-5","article-title":"Comparison between thromboelastography and thromboelastometry","volume":"85","author":"Sakai","year":"2019","journal-title":"Minerva Anestesiol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0155","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1055\/s-0038-1666861","article-title":"Concepts and controversies in haemostasis and thrombosis associated with liver disease: proceedings of the 7th international coagulation in liver disease conference","volume":"118","author":"Intagliata","year":"2018","journal-title":"Thromb Haemost."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0160","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1002\/cld.976","article-title":"Current concepts in coagulation profile in cirrhosis and acute-on-chronic liver failure","volume":"16","author":"Premkumar","year":"2020","journal-title":"Clin Liver Dis."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0165","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1016\/j.jvir.2019.04.017","volume":"30","author":"Patel","year":"2019","journal-title":"J Vasc Interv Radiol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0170","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.1056\/NEJMra1206531","article-title":"Management of antithrombotic therapy in patients undergoing invasive procedures","volume":"368","author":"Baron","year":"2013","journal-title":"N Engl J Med."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0175","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1016\/j.jvir.2016.05.010","article-title":"Utility of intravascular us-guided portal vein access during transjugular intrahepatic portosystemic shunt creation: retrospective comparison with conventional technique in 109 patients","volume":"27","author":"Pillai","year":"2016","journal-title":"J Vasc Interv Radiol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0180","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.cld.2008.09.007","article-title":"Blood products, volume control, and renal support in the coagulopathy of liver disease","volume":"13","author":"Argo","year":"2009","journal-title":"Clin Liver Dis."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0185","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/j.cgh.2010.03.025","article-title":"Complication rate of percutaneous liver biopsies among persons with advanced chronic liver disease in the HALT-C trial","volume":"8","author":"Seeff","year":"2010","journal-title":"Clin Gastroenterol Hepatol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0190","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1002\/hep.21266","article-title":"Thrombin generation in patients with cirrhosis: the role of platelets","volume":"44","author":"Tripodi","year":"2006","journal-title":"Hepatology."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0195","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.cld.2020.04.009","article-title":"Thrombocytopenia in chronic liver disease: new management strategies","volume":"24","author":"Nilles","year":"2020","journal-title":"Clin Liver Dis."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0200","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1055\/s-0040-1715451","article-title":"Thrombopoietin receptor agonists in patients with chronic liver disease","volume":"46","author":"Khemichian","year":"2020","journal-title":"Semin Thromb Hemost."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0205","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/hta24510","article-title":"Avatrombopag and lusutrombopag for thrombocytopenia in people with chronic liver disease needing an elective procedure: a systematic review and cost-effectiveness analysis","volume":"24","author":"Armstrong","year":"2020","journal-title":"Health Technol Assess."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0210","first-page":"136","article-title":"Avatrombopag for the management of thrombocytopenia in patients with chronic liver disease","volume":"113","author":"Lozano","year":"2021","journal-title":"Rev Esp Enferm Dig."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0215","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1111\/liv.12038","article-title":"Global hemostasis tests in patients with cirrhosis before and after prophylactic platelet transfusion","volume":"33","author":"Tripodi","year":"2013","journal-title":"Liver Int."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0220","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1111\/liv.13056","article-title":"Transfusion strategies in patients with cirrhosis: less is more","volume":"36","author":"Fatourou","year":"2016","journal-title":"Liver Int."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0225","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/ejh.13342","article-title":"Transfusion strategies in patients with cirrhosis","volume":"104","author":"Liu","year":"2020","journal-title":"Eur J Haematol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0230","doi-asserted-by":"crossref","first-page":"830","DOI":"10.5604\/01.3001.0012.0775","article-title":"Low fibrinogen levels are associated with bleeding after varices ligation in thrombocytopenic cirrhotic patients","volume":"17","author":"Giannini","year":"2018","journal-title":"Ann Hepatol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0235","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1093\/bja\/aen270","article-title":"Fibrinogen concentrate substitution therapy in patients with massive haemorrhage and low plasma fibrinogen concentrations","volume":"101","author":"Fenger-Eriksen","year":"2008","journal-title":"Br J Anaesth."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0240","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1097\/ALN.0b013e3181f22b5a","article-title":"Pathophysiology and treatment of coagulopathy in massive hemorrhage and hemodilution","volume":"113","author":"Bolliger","year":"2010","journal-title":"Anesthesiology."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0245","doi-asserted-by":"crossref","first-page":"2006","DOI":"10.1111\/j.1537-2995.2009.02295.x","article-title":"Is preoperative fibrinogen predictive for postoperative bleeding after coronary artery bypass grafting surgery?","volume":"49","author":"Bolliger","year":"2009","journal-title":"Transfusion."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0250","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.transci.2004.04.003","article-title":"Pharmacokinetic properties of a pasteurised fibrinogen concentrate","volume":"32","author":"Kreuz","year":"2005","journal-title":"Transfus Apher Sci."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0255","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1111\/imj.13766","article-title":"Suboptimal use of pharmacological venous thromboembolism prophylaxis in cirrhotic patients","volume":"48","author":"Yang","year":"2018","journal-title":"Intern Med J."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0260","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.jhepr.2019.02.006","article-title":"Anticoagulation in the cirrhotic patient","volume":"1","author":"Turco","year":"2019","journal-title":"JHEP Rep."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0265","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1002\/phar.1218","article-title":"Evaluation of pharmacologic prophylaxis for venous thromboembolism in patients with chronic liver disease","volume":"33","author":"Barclay","year":"2013","journal-title":"Pharmacotherapy."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0270","doi-asserted-by":"crossref","first-page":"e97","DOI":"10.1038\/ctg.2015.27","article-title":"Cirrhosis is associated with an increased 30-day mortality after venous thromboembolism","volume":"6","author":"S\u00f8gaard","year":"2015","journal-title":"Clin Transl Gastroenterol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0275","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1161\/JAHA.116.005307","article-title":"Liver cirrhosis in patients with atrial fibrillation: Would oral anticoagulation have a net clinical benefit for stroke prevention?","volume":"6","author":"Kuo","year":"2017","journal-title":"J Am Heart Assoc."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0280","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1002\/hep.27783","article-title":"Impact of anticoagulation on upper-gastrointestinal bleeding in cirrhosis. A retrospective multicenter study","volume":"62","author":"Cerini","year":"2015","journal-title":"Hepatology."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0285","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/4383269","article-title":"Direct oral anticoagulants in cirrhotic patients: current evidence and clinical observations","volume":"2019","author":"Elhosseiny","year":"2019","journal-title":"Can J Gastroenterol Hepatol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0290","doi-asserted-by":"crossref","first-page":"5737","DOI":"10.3748\/wjg.v20.i19.5737","article-title":"Deep vein thrombosis and pulmonary embolism in cirrhotic patients: Systematic review","volume":"20","author":"Aggarwal","year":"2014","journal-title":"World J Gastroenterol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0295","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1477-9560-9-1","article-title":"The incidence of venous thromboembolism and practice of deep venous thrombosis prophylaxis in hospitalized cirrhotic patients","volume":"9","author":"Aldawood","year":"2011","journal-title":"Thromb J."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0300","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1002\/hep.1840160515","article-title":"The incidence of portal vein thrombosis at liver transplantation","volume":"16","author":"Nonami","year":"1992","journal-title":"Hepatology."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0305","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/0016-5085(85)90327-0","article-title":"Incidence of portal vein thrombosis in liver cirrhosis. An angiographic study in 708 patients","volume":"89","author":"Okuda","year":"1985","journal-title":"Gastroenterology."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0310","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/S1499-3872(16)60092-9","article-title":"Incidence and clinical presentation of portal vein thrombosis in cirrhotic patients","volume":"15","author":"Cagin","year":"2016","journal-title":"Hepatobiliary Pancreat Dis Int."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0315","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000025439","article-title":"Effect of portal vein thrombosis on the prognosis of patients with cirrhosis without a liver transplant: a systematic review and metaanalysis","volume":"100","author":"Xian","year":"2021","journal-title":"Medicine (Baltimore)."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0320","first-page":"66","article-title":"Portal vein grafts in hepatic transplantation","volume":"161","author":"Shaw","year":"1985","journal-title":"Surg Gynecol Obstet."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0325","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.jceh.2014.12.008","article-title":"Portal vein thrombosis","volume":"5","author":"Chawla","year":"2015","journal-title":"J Clin Exp Hepatol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0330","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1097\/00007890-200005150-00023","article-title":"Portal vein thrombosis in adults undergoing liver transplantation: Risk factors, screening, management, and outcome","volume":"69","author":"Yerdel","year":"2000","journal-title":"Transplantation."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0335","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1111\/j.1399-0012.2010.01217.x","article-title":"Clinical analysis of living donor liver transplantation in patients with portal vein thrombosis","volume":"25","author":"Kim","year":"2011","journal-title":"Clin Transplant."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0340","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.hpb.2015.10.008","article-title":"Pre-transplant portal vein thrombosis is an independent risk factor for graft loss due to hepatic artery thrombosis in liver transplant recipients","volume":"18","author":"Stine","year":"2016","journal-title":"HPB."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0345","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1002\/cld.939","article-title":"CON: Portal vein thrombosis does not impact liver transplantation outcomes","volume":"16","author":"Sherman","year":"2020","journal-title":"Clin Liver Dis."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0350","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1002\/cld.932","article-title":"PRO: Portal vein thrombosis impacts liver transplantation outcomes","volume":"16","author":"Agbim","year":"2020","journal-title":"Clin Liver Dis."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0355","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1002\/hep.23259","article-title":"Acute portal vein thrombosis unrelated to cirrhosis: A prospective multicenter follow-up study","volume":"51","author":"Plessier","year":"2010","journal-title":"Hepatology."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0360","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1097\/00007890-200005150-00006","article-title":"Changing perspectives in portal vein thrombosis and liver transplantation","volume":"69","author":"Jamieson","year":"2000","journal-title":"Transplantation."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0365","doi-asserted-by":"crossref","first-page":"3904","DOI":"10.1016\/j.transproceed.2005.09.120","article-title":"Portal vein thrombosis in liver transplantation","volume":"37","author":"Charco","year":"2005","journal-title":"Transplant Proc."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0370","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1002\/hep.27546","article-title":"Causes and consequences of portal vein thrombosis in 1,243 patients with cirrhosis: Results of a longitudinal study","volume":"61","author":"Nery","year":"2015","journal-title":"Hepatology."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0375","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1111\/liv.13500","article-title":"Decreased portal vein velocity is predictive of the development of portal vein thrombosis: a matched case-control study","volume":"38","author":"Stine","year":"2018","journal-title":"Liver Int."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0380","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1038\/ajg.2012.452","article-title":"De novo portal vein thrombosis in virus-related cirrhosis: predictive factors and long-term outcomes","volume":"108","author":"Maruyama","year":"2013","journal-title":"Am J Gastroenterol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0385","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/j.jhep.2009.03.013","article-title":"Thrombotic risk factors in patients with liver cirrhosis: correlation with MELD scoring system and portal vein thrombosis development","volume":"51","author":"Zocco","year":"2009","journal-title":"J Hepatol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0390","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1097\/MEG.0000000000000352","article-title":"Procoagulant imbalance aggravated with falling liver function reserve, but not associated with the presence of portal vein thrombosis in cirrhosis","volume":"27","author":"Tang","year":"2015","journal-title":"Eur J Gastroenterol Hepatol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0395","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.jaut.2005.01.016","article-title":"Prevalence and clinical significance of anticardiolipin antibodies in patients with type 1 autoimmune hepatitis","volume":"24","author":"Liaskos","year":"2005","journal-title":"J Autoimmun."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0400","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1053\/jlts.2001.21295","article-title":"Liver transplantation in patients with portal vein thrombosis","volume":"7","author":"Manzanet","year":"2001","journal-title":"Liver Transplant."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0405","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1097\/00007890-199404270-00006","article-title":"Incidence, risk factors, management, and outcome of portal vein abnormalities at orthotopic liver transplantation","volume":"57","author":"Davidson","year":"1994","journal-title":"Transplantation."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0410","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/ctr.13001","article-title":"Increased risk of portal vein thrombosis in patients with autoimmune hepatitis on the liver transplantation waiting list","volume":"31","author":"Ruiz","year":"2017","journal-title":"Clin Transplant."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0415","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1007\/s12029-018-0149-5","article-title":"Acute portal vein thrombosis predicts concomitant diagnosis of hepatocellular carcinoma in cirrhotic patients","volume":"50","author":"Khoury","year":"2019","journal-title":"J Gastrointest Cancer."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0420","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1007\/s004320050189","article-title":"Portal vein thrombosis in hepatocellular carcinoma: age and sex distribution in an autopsy study","volume":"124","author":"Pirisi","year":"1998","journal-title":"J Cancer Res Clin Oncol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0425","first-page":"386","article-title":"Natural history of untreated primary hepatocellular carcinoma: a retrospective study of 157 patients","volume":"21","author":"Pawarode","year":"1998","journal-title":"Am J Clin Oncol Cancer Clin Trials."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0430","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.dld.2016.11.013","article-title":"Portal vein thrombosis: the role of imaging in the clinical setting","volume":"49","author":"Margini","year":"2017","journal-title":"Dig Liver Dis."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0435","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.jhep.2018.03.019","article-title":"EASL clinical practice guidelines: management of hepatocellular carcinoma","volume":"69","author":"Galle","year":"2018","journal-title":"J Hepatol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0440","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1002\/hep.29913","article-title":"Diagnosis, Staging, and Management of Hepatocellular Carcinoma: 2018 Practice Guidance by the American Association for the Study of Liver Diseases","volume":"68","author":"Marrero","year":"2018","journal-title":"Hepatology."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0445","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1080\/21678707.2016.1215907","article-title":"Portal vein thrombosis in cirrhotic and non cirrhotic patients: from diagnosis to treatment","volume":"4","author":"Dell\u2019Era","year":"2016","journal-title":"Expert Opin Orphan Drugs."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0450","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.jhep.2015.07.001","article-title":"Individualized care for portal hypertension: not quite yet","volume":"63","author":"Kamath","year":"2015","journal-title":"J Hepatol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0455","doi-asserted-by":"crossref","first-page":"18","DOI":"10.14309\/ajg.0000000000000486","article-title":"ACG clinical guideline: disorders of the hepatic and mesenteric circulation","volume":"115","author":"Simonetto","year":"2020","journal-title":"Am J Gastroenterol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0460","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1097\/MOT.0000000000000506","article-title":"Portal vein thrombosis: yes or no on anticoagulation therapy","volume":"23","author":"Turon","year":"2018","journal-title":"Curr Opin Organ Transplant."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0465","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1053\/j.gastro.2019.01.265","article-title":"Diagnosis, development, and treatment of portal vein thrombosis in patients with and without cirrhosis","volume":"156","author":"Intagliata","year":"2019","journal-title":"Gastroenterology."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0470","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1053\/j.gastro.2017.04.042","article-title":"Effects of anticoagulants in patients with cirrhosis and portal vein thrombosis: a systematic review and meta-analysis","volume":"153","author":"Loffredo","year":"2017","journal-title":"Gastroenterology."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0475","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1002\/lt.24387","article-title":"Nontumoral portal vein thrombosis in patients awaiting liver transplantation","volume":"22","author":"Chen","year":"2016","journal-title":"Liver Transplant."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0480","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.118.011112","article-title":"Effectiveness and safety of non\u2013vitamin K antagonist oral anticoagulant and warfarin in cirrhotic patients with nonvalvular atrial fibrillation","volume":"8","author":"Lee","year":"2019","journal-title":"J Am Heart Assoc."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0485","doi-asserted-by":"crossref","first-page":"3295","DOI":"10.1016\/j.jacc.2019.04.052","article-title":"Direct oral anticoagulants in patients with atrial fibrillation and liver disease","volume":"73","author":"Lee","year":"2019","journal-title":"J Am Coll Cardiol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0490","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.vph.2018.05.002","article-title":"Randomized controlled trial of rivaroxaban versus warfarin in the management of acute non-neoplastic portal vein thrombosis","volume":"113","author":"Hanafy","year":"2019","journal-title":"Vascul Pharmacol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0495","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1111\/hepr.12895","article-title":"Efficacy and safety of edoxaban for treatment of portal vein thrombosis following danaparoid sodium in patients with liver cirrhosis","volume":"48","author":"Nagaoki","year":"2018","journal-title":"Hepatol Res."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0500","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1002\/lt.24708","article-title":"Reversal of direct oral anticoagulants for liver transplantation in cirrhosis: a step forward","volume":"23","author":"Intagliata","year":"2017","journal-title":"Liver Transplant."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0505","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1111\/apt.15479","article-title":"A stepwise thrombolysis regimen in the management of acute portal vein thrombosis in patients with evidence of intestinal ischaemia","volume":"50","author":"Benmassaoud","year":"2019","journal-title":"Aliment Pharmacol Ther."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0510","doi-asserted-by":"crossref","first-page":"2347","DOI":"10.1097\/TP.0000000000000729","article-title":"Pretransplant portal vein recanalization-transjugular intrahepatic portosystemic shunt in patients with complete obliterative portal vein thrombosis","volume":"99","author":"Salem","year":"2015","journal-title":"Transplantation."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0515","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1016\/j.jvir.2017.08.005","article-title":"Pretransplantation portal vein recanalization and transjugular intrahepatic portosystemic shunt creation for chronic portal vein thrombosis: final analysis of a 61-patient cohort","volume":"28","author":"Thornburg","year":"2017","journal-title":"J Vasc Interv Radiol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0520","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1002\/hep.30915","article-title":"Mixed fibrinolytic phenotypes in decompensated cirrhosis and acute-on-chronic liver failure with hypofibrinolysis in those with complications and poor survival","volume":"71","author":"Blasi","year":"2020","journal-title":"Hepatology."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0525","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1016\/j.dld.2019.03.011","article-title":"Acute kidney injury is associated with low factor XIII in decompensated cirrhosis","volume":"51","author":"Intagliata","year":"2019","journal-title":"Dig Liver Dis."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0530","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1002\/hep.31443","article-title":"Acute kidney injury in decompensated cirrhosis is associated with both hypo-coagulable and hyper-coagulable features","volume":"72","author":"Zanetto","year":"2020","journal-title":"Hepatology."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0535","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.1002\/hep.30103","article-title":"Coagulation failure in patients with acute-on-chronic liver failure and decompensated cirrhosis: beyond the international normalized ratio","volume":"68","author":"Blasi","year":"2018","journal-title":"Hepatology."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0540","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1111\/jth.12706","article-title":"Cirrhosis patients have a coagulopathy that is associated with decreased clot formation capacity","volume":"12","author":"Kleinegris","year":"2014","journal-title":"J Thromb Haemost."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0545","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1002\/hep.21303","article-title":"Coagulation disorders and hemostasis in liver disease: pathophysiology and critical assessment of current management","volume":"44","author":"Caldwell","year":"2006","journal-title":"Hepatology."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0550","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.cld.2008.10.001","article-title":"Coagulopathy of acute liver failure","volume":"13","author":"Munoz","year":"2009","journal-title":"Clin Liver Dis."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0555","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.cld.2018.01.013","article-title":"Management of acute liver failure in the intensive care unit setting","volume":"22","author":"Rajaram","year":"2018","journal-title":"Clin Liver Dis."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0560","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1055\/s-0035-1550430","article-title":"Rebalanced hemostasis in patients with acute liver failur","volume":"41","author":"Lisman","year":"2015","journal-title":"Semin Thromb Hemost."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0565","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1111\/liv.12369","article-title":"Evidence of rebalanced coagulation in acute liver injury and acute liver failure as measured by thrombin generation","volume":"34","author":"Habib","year":"2014","journal-title":"Liver Int."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0570","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1111\/j.1365-2036.2007.03369.x","article-title":"Review article: the prothrombin time test as a measure of bleeding risk and prognosis in liver disease","volume":"26","author":"Tripodi","year":"2007","journal-title":"Aliment Pharmacol Ther."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0575","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1002\/cld.947","article-title":"Thromboelastography and utility in hepatology practice","volume":"16","author":"Shenoy","year":"2020","journal-title":"Clin Liver Dis."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0580","doi-asserted-by":"crossref","first-page":"3552","DOI":"10.1016\/j.transproceed.2018.07.032","article-title":"Review: the perioperative use of thromboelastography for liver transplant patients","volume":"50","author":"Hawkins","year":"2018","journal-title":"Transplant Proc."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0585","doi-asserted-by":"crossref","first-page":"384","DOI":"10.14218\/JCTH.2019.00032","article-title":"Intensive care management of acute liver failure: considerations while awaiting liver transplantation","volume":"7","author":"Seetharam","year":"2019","journal-title":"J Clin Transl Hepatol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0590","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/j.jhep.2012.06.020","article-title":"Evaluation of coagulation abnormalities in acute liver failure","volume":"57","author":"Agarwal","year":"2012","journal-title":"J Hepatol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0595","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1016\/j.jhep.2016.12.003","article-title":"EASL clinical practical guidelines on the management of acute (fulminant) liver failure","volume":"66","author":"Wendon","year":"2017","journal-title":"J Hepatol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0600","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1097\/CCM.0000000000004193","article-title":"Guidelines for the management of adult acute and acute-on-chronic liver failure in the ICU: cardiovascular, endocrine, hematologic, pulmonary and renal considerations: executive summary","volume":"48","author":"Nanchal","year":"2020","journal-title":"Crit Care Med."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0605","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.gastrohep.2018.07.013","article-title":"Management of acute liver failure. Clinical guideline from the Catalan Society of Digestology","volume":"42","author":"Escorsell","year":"2019","journal-title":"Gastroenterol Hepatol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0610","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.tmrv.2017.06.002","article-title":"Management of hemostatic disorders in patients with advanced liver disease admitted to an intensive care unit","volume":"31","author":"Lisman","year":"2017","journal-title":"Transfus Med Rev."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0615","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1213\/00000539-198509000-00008","article-title":"Intraoperative changes in blood coagulation and thrombelastographic monitoring in liver transplantation","volume":"64","author":"Kang","year":"1985","journal-title":"Anesth Analg."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0620","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1097\/MCG.0000000000001285","article-title":"Thromboelastography better reflects hemostatic abnormalities in cirrhotics compared with the international normalized ratio","volume":"54","author":"Hum","year":"2020","journal-title":"J Clin Gastroenterol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0625","doi-asserted-by":"crossref","first-page":"205","DOI":"10.5604\/01.3001.0010.8635","article-title":"Viscoelastic testing in liver disease","volume":"17","author":"Davis","year":"2018","journal-title":"Ann Hepatol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0630","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1016\/j.transproceed.2012.05.004","article-title":"Coagulopathy management in liver transplantation","volume":"44","author":"Sabate","year":"2012","journal-title":"Transplant Proc."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0635","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.3748\/wjg.v22.i4.1541","article-title":"Hemostasis in liver transplantation: pathophysiology, monitoring, and treatment","volume":"22","author":"Hartmann","year":"2016","journal-title":"World J Gastroenterol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0640","doi-asserted-by":"crossref","first-page":"345","DOI":"10.5500\/wjt.v10.i11.345","article-title":"Intraoperative thromboelastography as a tool to predict postoperative thrombosis during liver transplantation","volume":"10","author":"De Pietri","year":"2020","journal-title":"World J Transplant."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0645","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.sopen.2019.12.004","article-title":"Perioperative thrombelastography serves as an important assessment tool of transfusion requirements during liver transplantation","volume":"2","author":"Graff","year":"2020","journal-title":"Surg Open Sci."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0650","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1213\/ANE.0000000000002394","article-title":"The coagulation profile of end-stage liver disease and considerations for intraoperative management","volume":"126","author":"Forkin","year":"2018","journal-title":"Anesth Analg."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0655","doi-asserted-by":"crossref","first-page":"2590","DOI":"10.1016\/j.transproceed.2010.05.144","article-title":"Thromboelastography-guided transfusion decreases intraoperative blood transfusion during orthotopic liver transplantation: randomized clinical trial","volume":"42","author":"Wang","year":"2010","journal-title":"Transplant Proc."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0660","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1002\/hep.28148","article-title":"Thrombelastography-guided blood product use before invasive procedures in cirrhosis with severe coagulopathy: a randomized, controlled trial","volume":"63","author":"De Pietri","year":"2016","journal-title":"Hepatology."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0665","doi-asserted-by":"crossref","first-page":"e49","DOI":"10.1097\/TXD.0000000000000559","article-title":"Reduced transfusion during OLT by POC coagulation management and TEG functional fibrinogen","volume":"2","author":"De Pietri","year":"2016","journal-title":"Transplant Direct."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0670","doi-asserted-by":"crossref","first-page":"3637","DOI":"10.1016\/j.transproceed.2013.11.008","article-title":"Is \u2018intra-operating room\u2019 thromboelastometry useful in liver transplantation? A case-control study in 303 patients","volume":"45","author":"\u00c1lamo","year":"2013","journal-title":"Transplant Proc."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0675","doi-asserted-by":"crossref","first-page":"916","DOI":"10.5604\/01.3001.0010.5283","article-title":"Rotational thromboelastometry or conventional coagulation tests in liver transplantation: comparing blood loss, transfusions, and cost","volume":"16","author":"Smart","year":"2017","journal-title":"Ann Hepatol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0680","doi-asserted-by":"crossref","first-page":"828","DOI":"10.5604\/01.3001.0010.5270","article-title":"The optimal transfusion strategy in liver transplantation: the quest continues","volume":"16","author":"Intagliata","year":"2017","journal-title":"Ann Hepatol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0685","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/S0140-6736(76)91794-3","article-title":"Correction of abnormal coagulation in chronic liver disease by combined use of fresh-frozen plasma and prothrombin complex concentrates","volume":"308","author":"Mannucci","year":"1976","journal-title":"Lancet."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0690","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/cc8186","article-title":"Prothrombin complex concentrate in surgical patients: retrospective evaluation of vitamin K antagonist reversal and treatment of severe bleeding","volume":"13","author":"Schick","year":"2009","journal-title":"Crit Care."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0695","first-page":"149","article-title":"Prothrombin complex concentrates: an update","volume":"8","author":"Franchini","year":"2010","journal-title":"Blood Transfus."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0700","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.bpa.2020.03.002","article-title":"Coagulation, hemostasis, and transfusion during liver transplantation","volume":"34","author":"Thai","year":"2020","journal-title":"Best Pract Res Clin Anaesthesiol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0705","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1002\/phar.1827","article-title":"Comparison of fresh-frozen plasma, four-factor prothrombin complex concentrates, and recombinant factor VIIa to facilitate procedures in critically ill patients with coagulopathy from liver disease: a retrospective cohort study","volume":"36","author":"Kwon","year":"2016","journal-title":"Pharmacotherapy."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0710","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1111\/ctr.13435","article-title":"Utility of prothrombin complex concentrate as first-line treatment modality of coagulopathy in patients undergoing liver transplantation: a propensity score-matched study","volume":"32","author":"Srivastava","year":"2018","journal-title":"Clin Transplant."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0715","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/vox.12021","article-title":"Solvent detergent vs. fresh frozen plasma in cirrhotic patients undergoing liver transplant surgery: a prospective randomized control study","volume":"105","author":"Bindi","year":"2013","journal-title":"Vox Sang."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0720","doi-asserted-by":"crossref","first-page":"339","DOI":"10.5603\/AIT.a2015.0011","article-title":"Tranexamic acid: a clinical review","volume":"47","author":"Ng","year":"2015","journal-title":"Anaesthesiol Intensive Ther."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0725","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1111\/j.1600-6143.2006.01591.x","article-title":"Efficacy and safety of antifibrinolytic drugs in liver transplantation: a systematic review and meta-analysis","volume":"7","author":"Molenaar","year":"2007","journal-title":"Am J Transplant."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0730","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1097\/01.aia.0000210804.39545.66","article-title":"Antifibrinolytics in liver transplantation","volume":"44","author":"Groenland","year":"2006","journal-title":"Int Anesthesiol Clin."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0735","first-page":"568","article-title":"Low plasma fibrinogen levels and blood product transfusion in liver transplantation","volume":"80","author":"Costa","year":"2014","journal-title":"Minerva Anestesiol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0740","doi-asserted-by":"crossref","DOI":"10.12659\/AOT.923665","article-title":"Importance of intraoperative transfusions of packed red blood cells and fresh frozen plasma in liver transplantation for hepatocellular cancer","volume":"25","author":"Masior","year":"2020","journal-title":"Ann Transplant."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0745","doi-asserted-by":"crossref","first-page":"782","DOI":"10.23736\/S0375-9393.19.13468-2","article-title":"Perioperative hemostatic management in the cirrhotic patient: a position paper on behalf of the Liver Intensive Care Group of Europe (LICAGE)","volume":"85","author":"Biancofiore","year":"2019","journal-title":"Minerva Anestesiol."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0750","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1097\/00000542-199611000-00012","article-title":"Tranexamic acid reduces blood loss, transfusion requirements, and coagulation factor use in primary orthotopic liver transplantation","volume":"85","author":"Boylan","year":"1996","journal-title":"Anesthesiology."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0755","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1111\/j.1600-6143.2006.01591.x","article-title":"Efficacy and safety of antifibrinolytic drugs in liver transplantation: a systematic review and metaanalysis","volume":"7","author":"Molenaar","year":"2007","journal-title":"Am J Transplant."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0760","doi-asserted-by":"crossref","first-page":"2925","DOI":"10.1016\/j.transproceed.2015.10.025","article-title":"Fibrinogen: a clinical update on liver transplantation","volume":"47","author":"Sabate","year":"2015","journal-title":"Transplant Proc."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0765","doi-asserted-by":"crossref","first-page":"2973","DOI":"10.1016\/j.transproceed.2010.08.011","article-title":"Introduction of fibrinogen in the treatment of hemostatic disorders during orthotopic liver transplantation: implications in the use of allogenic blood","volume":"42","author":"Noval-Padillo","year":"2010","journal-title":"Transplant Proc."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0770","doi-asserted-by":"crossref","first-page":"2421","DOI":"10.1111\/ajt.13752","article-title":"Impact of preemptive fibrinogen concentrate on transfusion requirements in liver transplantation: a multicenter, randomized, double-blind, placebo-controlled trial","volume":"16","author":"Sabate","year":"2016","journal-title":"Am J Transplant."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0775","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1093\/bja\/aeu158","article-title":"Cryoprecipitate therapy","volume":"113","author":"Nascimento","year":"2014","journal-title":"Br J Anaesth."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0780","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1002\/lt.25198","article-title":"Management of coagulation and anticoagulation in liver transplantation candidates","volume":"24","author":"Northup","year":"2018","journal-title":"Liver Transplant."},{"key":"10.1016\/j.rgmxen.2023.08.008_bib0785","first-page":"319","article-title":"Thromboelastography and Thromboelastometry","volume":"50","author":"Sol-L\u00f3pez","year":"2016","journal-title":"Acta Bioqu\u00edm Cl\u00edn Latinoam."}],"container-title":["Revista de Gastroenterolog\u00eda de M\u00e9xico (English Edition)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2255534X24000124?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2255534X24000124?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T08:53:10Z","timestamp":1762419190000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2255534X24000124"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":157,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["S2255534X24000124"],"URL":"https:\/\/doi.org\/10.1016\/j.rgmxen.2023.08.008","relation":{},"ISSN":["2255-534X"],"issn-type":[{"value":"2255-534X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Guidelines for the management of coagulation disorders in patients with cirrhosis","name":"articletitle","label":"Article Title"},{"value":"Revista de Gastroenterolog\u00eda de M\u00e9xico (English Edition)","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rgmxen.2023.08.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.rgmx.2023.08.007","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Asociaci\u00f3n Mexicana de Gastroenterolog\u00eda. Published by Masson Doyma M\u00e9xico S.A.","name":"copyright","label":"Copyright"}]}}