{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T00:34:15Z","timestamp":1745368455849},"reference-count":37,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Revista Iberoamericana de Micolog\u00eda"],"published-print":{"date-parts":[[2012,1]]},"DOI":"10.1016\/j.riam.2011.04.001","type":"journal-article","created":{"date-parts":[[2011,6,13]],"date-time":"2011-06-13T05:10:23Z","timestamp":1307941823000},"page":"24-28","source":"Crossref","is-referenced-by-count":9,"title":["Actividad antif\u00fangica in vitro del ajoeno en cinco aislamientos cl\u00ednicos de Histoplasma capsulatum var. capsulatum"],"prefix":"10.1016","volume":"29","author":[{"given":"Joel","family":"Torres","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hilda","family":"Romero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.riam.2011.04.001_bib0005","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/0049-3848(83)90027-0","article-title":"Effects of garlic extract and three pure components isolated from it on human platelet aggregation","volume":"32","author":"Apitz-Castro","year":"1983","journal-title":"Thromb Res"},{"key":"10.1016\/j.riam.2011.04.001_bib0010","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.diagmicrobio.2008.05.006","article-title":"Histoplasmosis in HIV infected patients in a southern regional medical center: poor prognosis in the era of highly active antiretroviral therapy","volume":"62","author":"Baddley","year":"2008","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.riam.2011.04.001_bib0015","doi-asserted-by":"crossref","first-page":"7045","DOI":"10.1021\/ja00282a033","article-title":"Antithrombotic organosulfur compounds from garlic: structural, mechanistic and synthetic studies","volume":"108","author":"Block","year":"1986","journal-title":"J Am Chem Soc"},{"key":"10.1016\/j.riam.2011.04.001_bib0020","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1093\/jac\/dkg144","article-title":"The in vitro susceptibility of Scedosporium prolificans to ajoene, allitridium and a raw extract of garlic (Allium sativum)","volume":"51","author":"Davis","year":"2003","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.riam.2011.04.001_bib0025","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1093\/jac\/49.suppl_1.7","article-title":"Anfotericina B: spectrum and resistance","volume":"49","author":"Ellis","year":"2002","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.riam.2011.04.001_bib0030","first-page":"277","article-title":"Efectos del ajoeno sobre dermatofitos, Candida albicans y Malassezia furfur","volume":"15","author":"Gonz\u00e1lez de","year":"1998","journal-title":"Rev Iberoam Micol"},{"key":"10.1016\/j.riam.2011.04.001_bib0035","first-page":"10","article-title":"Casu\u00edstica de las micosis profundas 1984-2008. 24 a\u00f1os de historia","volume":"42","year":"2009","journal-title":"Bol Inform Las Micosis en Venezuela"},{"key":"10.1016\/j.riam.2011.04.001_bib0040","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.ccm.2009.02.002","article-title":"Histoplasmosis","volume":"30","author":"Kauffman","year":"2009","journal-title":"Clin Chest Med"},{"key":"10.1016\/j.riam.2011.04.001_bib0045","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1111\/j.1439-0507.1996.tb00160.x","article-title":"Efficacy of ajoene, an organosulphur derived from garlic in short term therapy of Tinea pedis","volume":"39","author":"Ledezma","year":"1996","journal-title":"Mycoses"},{"key":"10.1016\/j.riam.2011.04.001_bib0050","first-page":"544","article-title":"Ajoene in the topical short-term treatment of Tinea cruris and Tinea corporis in humans","volume":"49","author":"Ledezma","year":"1999","journal-title":"Drug Res"},{"key":"10.1016\/j.riam.2011.04.001_bib0055","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S1130-1406(08)70037-8","article-title":"Sinergismo entre ajoeno y ketoconazol en aislamientos de Microsporum canis. Un estudio preliminar mediante la determinaci\u00f3n de la concentraci\u00f3n inhibitoria fraccional (CIF)","volume":"25","author":"Ledezma","year":"2008","journal-title":"Rev Iberoam Micol"},{"key":"10.1016\/j.riam.2011.04.001_bib0060","first-page":"34","article-title":"Susceptibilidad in vitro al ajoene de aislados de C\u00e1ndida albicans, C. parapsilopsis y C. krusei obtenidos de pacientes con onicomicosis y su relaci\u00f3n con el tratamiento t\u00f3pico","volume":"24","author":"Lemus","year":"2004","journal-title":"Rev Soc Ven Microbiol"},{"key":"10.1016\/j.riam.2011.04.001_bib0065","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1157\/13050528","article-title":"Antif\u00fangicos de uso sist\u00e9mico","volume":"21","author":"Lumbreras","year":"2003","journal-title":"Enferm Infecc Microbiol Clin"},{"key":"10.1016\/j.riam.2011.04.001_bib0070","first-page":"40","article-title":"Estudio de la susceptibilidad in vitro de aislados de Microsporum canis al ajoene, terbinafina y griseofulvina, utilizando el m\u00e9todo de microdiluci\u00f3n","volume":"24","author":"Maniscalchi","year":"2004","journal-title":"Rev Soc Ven Microbiol"},{"key":"10.1016\/j.riam.2011.04.001_bib0075","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S1130-1406(08)70038-X","article-title":"Antifungal activity of ajoene on experimental murine paracoccidioidomycosis","volume":"25","author":"Marcia","year":"2008","journal-title":"Rev Iberoam Micol"},{"key":"10.1016\/j.riam.2011.04.001_bib0080","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1080\/mmy.38.s1.269.279","article-title":"Mycoses associated with AIDS in the third world","volume":"38","author":"Marques","year":"2000","journal-title":"Med Mycol"},{"key":"10.1016\/j.riam.2011.04.001_bib0085","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1053\/srin.2001.24244","article-title":"Treatment of histoplasmosis","volume":"16","author":"Mocherla","year":"2001","journal-title":"Semin Respir Infect"},{"key":"10.1016\/j.riam.2011.04.001_bib0090","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1111\/j.1439-0507.2007.01459.x","article-title":"Disseminated histoplasmosis in acquired immunodeficiency syndrome patients in Uberaba, MG, Brazil","volume":"51","author":"Mora","year":"2007","journal-title":"Mycoses"},{"key":"10.1016\/j.riam.2011.04.001_bib0095","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S1130-1406(05)70005-X","article-title":"Inmunoan\u00e1lisis enzim\u00e1tico (ELISA) en la evoluci\u00f3n terap\u00e9utica de la cromoblastomicosis por Cladophialophora carrionii en el \u00e1rea end\u00e9mica del Estado Falc\u00f3n, Venezuela","volume":"22","author":"Oberto-Perdig\u00f3n","year":"2005","journal-title":"Rev Iberoam Micol"},{"key":"10.1016\/j.riam.2011.04.001_bib0100","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1080\/13693780310001616519","article-title":"Ajoene and 5-fluorouracil in the topical treatment of Cladophialophora carrionii chromoblastomycosis in humans: a comparative open study","volume":"41","author":"P\u00e9rez-Blanco","year":"2003","journal-title":"Med Mycol"},{"key":"10.1016\/j.riam.2011.04.001_bib0105","unstructured":"Reference Method for Broth Dilution Antifungal Susceptibility Testing of Filamentous Fungi; Approved Standard. NCCLS document M38-A2. NCCLS, 940 West Valley Road, Suite 1400, Wayne. Pensylvania 19087-1898 USA, 2008."},{"key":"10.1016\/j.riam.2011.04.001_bib0110","series-title":"Enfermedades Infecciosas","first-page":"316","article-title":"Histoplasmosis","author":"Restrepo","year":"2003"},{"key":"10.1016\/j.riam.2011.04.001_bib0115","first-page":"112","article-title":"Diagn\u00f3stico de las micosis sist\u00e9micas durante 5 a\u00f1os 2002-2006","volume":"27","author":"Revi\u00e1kina","year":"2007","journal-title":"Rev Soc Venez Microbiol"},{"key":"10.1016\/j.riam.2011.04.001_bib0120","first-page":"299","article-title":"Micosis como enfermedad del viajero","volume":"8","author":"Reyes","year":"2006","journal-title":"Inf M\u00e9d"},{"key":"10.1016\/j.riam.2011.04.001_bib0125","first-page":"181","article-title":"In vitro inhibitory effect of ajoene on Histoplasma capsulatum","volume":"14","author":"Romero","year":"2004","journal-title":"J Mycol Med"},{"key":"10.1016\/j.riam.2011.04.001_bib0130","first-page":"152","article-title":"In vitro antiproliferative effect of ajoene on Microsporum canis","volume":"10","author":"Romero","year":"2000","journal-title":"J Mycol Med"},{"key":"10.1016\/j.riam.2011.04.001_bib0135","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1128\/AAC.33.9.1641","article-title":"Inhibition of growth of the dimorphic fungus Paracoccidioides brasiliensis by ajoene","volume":"33","author":"San-Blas","year":"1989","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.riam.2011.04.001_bib0140","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1099\/00221287-143-5-1583","article-title":"Inhibition of Paracoccidioides brasiliensis by ajoene is associated with blockade of phosphatidylcholine biosynthesis","volume":"143","author":"San-Blas","year":"1997","journal-title":"Microbiology"},{"key":"10.1016\/j.riam.2011.04.001_bib0145","first-page":"99","article-title":"Actividad in vitro e in vivo del ajoeno sobre Coccidioides immitis","volume":"11","author":"S\u00e1nchez-Mirt","year":"1994","journal-title":"Rev Iberoam Micol"},{"key":"10.1016\/j.riam.2011.04.001_bib0150","first-page":"74","article-title":"Efecto inhibitorio y alteraciones ultraestructurales producidas por ajoeno sobre el crecimiento in vitro de los hongos demati\u00e1ceos: Cladosporium carrionii y Fonsecaea pedrosoi","volume":"10","author":"Sanchez-Mirt","year":"1993","journal-title":"Rev Iberoam Micol"},{"key":"10.1016\/j.riam.2011.04.001_bib0155","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1139\/b90-172","article-title":"Antifungal activity of ajoene, a constituent of garlic (Allium sativum)","volume":"68","author":"Singh","year":"1980","journal-title":"Can J Bot"},{"key":"10.1016\/j.riam.2011.04.001_bib0160","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1080\/13693780701651681","article-title":"Experimental paracoccidioidomycosis: alternative therapy with ajoene, compound from Allium sativum, associated with sulfamethoxale\/trimethoprim","volume":"46","author":"Thomas","year":"2008","journal-title":"Med Mycol"},{"key":"10.1016\/j.riam.2011.04.001_bib0165","first-page":"42","article-title":"Susceptibilidad in vitro de Histoplasma capsulatum al ajoene usando los m\u00e9todos de difusi\u00f3n en discos y pozos","volume":"26","author":"Torres","year":"2006","journal-title":"Rev Soc Ven Microbiol"},{"key":"10.1016\/j.riam.2011.04.001_bib0170","doi-asserted-by":"crossref","first-page":"2381","DOI":"10.1016\/0006-2952(93)90217-K","article-title":"Inhibition of phosphatidylcholine biosynthesis and cell proliferation in Trypanosoma cruzi by ajoene, an antiplatelet compound isolated from garlic","volume":"22","author":"Urbina","year":"1993","journal-title":"Biochem Pharmacol"},{"key":"10.1016\/j.riam.2011.04.001_bib0175","first-page":"149","article-title":"In vitro antiproliferative effect of Ajoene on Cryptococcus neoformans","volume":"12","author":"Vivas","year":"2002","journal-title":"J Mycol Med"},{"key":"10.1016\/j.riam.2011.04.001_bib0180","doi-asserted-by":"crossref","first-page":"1910","DOI":"10.1086\/323781","article-title":"Emergence of resistance to fluconazole as a cause of failure during treatment of histoplasmosis in patients with acquired immunodeficiency disease syndrome","volume":"33","author":"Wheat","year":"2001","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.riam.2011.04.001_bib0185","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1128\/AEM.53.3.615-617.1987","article-title":"Antifungal activity of ajoene derived from garlic","volume":"53","author":"Yoshida","year":"1987","journal-title":"Appl Environ Microbiol"}],"container-title":["Revista Iberoamericana de Micolog\u00eda"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1130140611000556?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1130140611000556?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,6,20]],"date-time":"2020-06-20T02:56:45Z","timestamp":1592621805000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1130140611000556"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["S1130140611000556"],"URL":"https:\/\/doi.org\/10.1016\/j.riam.2011.04.001","relation":{},"ISSN":["1130-1406"],"issn-type":[{"value":"1130-1406","type":"print"}],"subject":[],"published":{"date-parts":[[2012,1]]}}}