{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T01:37:17Z","timestamp":1791596237720,"version":"4.3.4"},"reference-count":110,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revista Iberoamericana de Micolog\u00eda"],"published-print":{"date-parts":[[2013,7]]},"DOI":"10.1016\/j.riam.2013.05.007","type":"journal-article","created":{"date-parts":[[2013,6,10]],"date-time":"2013-06-10T14:16:13Z","timestamp":1370873773000},"page":"179-188","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Recommendations for the management of candidemia in adults in Latin America"],"prefix":"10.1016","volume":"30","author":[{"given":"Marcio","family":"Nucci","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Thompson-Moya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Guzman-Blanco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iris Nora","family":"Tiraboschi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge Alberto","family":"Cortes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Echevarr\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose","family":"Sifuentes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeannete","family":"Zurita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda E.","family":"Santolaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tito","family":"Alvarado Matute","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavio","family":"de Queiroz Telles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnaldo Lopes","family":"Colombo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.riam.2013.05.007_bib0005","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1128\/JCM.43.4.1829-1835.2005","article-title":"Epidemiology and predictors of mortality in cases of Candida bloodstream infection: results from population-based surveillance, Barcelona, Spain, from 2002 to 2003","volume":"43","author":"Almirante","year":"2005","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.riam.2013.05.007_bib0010","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/S0002-9343(98)00030-8","article-title":"Predictors of adverse outcome in cancer patients with candidemia","volume":"104","author":"Anaissie","year":"1998","journal-title":"Am J Med"},{"key":"10.1016\/j.riam.2013.05.007_bib0015","series-title":"50th Interscience Conference on Antimicrobial Agents and Chemotherapy","article-title":"Impact of therapy on mortality across Candida spp. in patients with invasive candidiasis from randomized clinical trials: a patient level analysis","author":"Andes","year":"2010"},{"key":"10.1016\/j.riam.2013.05.007_bib0020","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1590\/S0036-46652004000500001","article-title":"Candidemia in a Brazilian tertiary care hospital: species distribution and antifungal susceptibility patterns","volume":"46","author":"Antunes","year":"2004","journal-title":"Rev Inst Med Trop Sao Paulo"},{"key":"10.1016\/j.riam.2013.05.007_bib0025","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1590\/S1413-86702005000500009","article-title":"Prevalence, susceptibility profile for fluconazole and risk factors for candidemia in a tertiary care hospital in southern Brazil","volume":"9","author":"Aquino","year":"2005","journal-title":"Braz J Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0030","unstructured":"Astellas. MYCAMINE (micafungin sodium) for injection. Product Information \u2013 United States. Revised June 2011."},{"key":"10.1016\/j.riam.2013.05.007_bib0035","doi-asserted-by":"crossref","first-page":"86S","DOI":"10.1016\/0002-9343(91)90349-3","article-title":"Secular trends in nosocomial primary bloodstream infections in the United States, 1980\u20131989. National Nosocomial Infections Surveillance System","volume":"91","author":"Banerjee","year":"1991","journal-title":"Am J Med"},{"key":"10.1016\/j.riam.2013.05.007_bib0040","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1111\/j.1365-2141.2007.06812.x","article-title":"Risks, diagnosis and outcomes of invasive fungal infections in haematopoietic stem cell transplant recipients","volume":"139","author":"Barnes","year":"2007","journal-title":"Br J Haematol"},{"key":"10.1016\/j.riam.2013.05.007_bib0045","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1080\/00365540410020703","article-title":"Candida endocarditis: contemporary cases from the International Collaboration of Infectious Endocarditis Merged Database (ICE-mD)","volume":"36","author":"Benjamin","year":"2004","journal-title":"Scand J Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0050","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1056\/NEJMct060052","article-title":"Echinocandins for candidemia in adults without neutropenia","volume":"355","author":"Bennett","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1016\/j.riam.2013.05.007_bib0055","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1093\/clinids\/21.2.361","article-title":"Invasive fungal disease in adults undergoing remission-induction therapy for acute myeloid leukemia: the pathogenetic role of the antileukemic regimen","volume":"21","author":"Bow","year":"1995","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0060","doi-asserted-by":"crossref","first-page":"2254","DOI":"10.1200\/JCO.1997.15.6.2254","article-title":"Cytotoxic therapy-induced d-xylose malabsorption and invasive infection during remission-induction therapy for acute myeloid leukemia in adults","volume":"15","author":"Bow","year":"1997","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.riam.2013.05.007_bib0065","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.1086\/421087","article-title":"Optimal testing parameters for blood cultures","volume":"38","author":"Cockerill","year":"2004","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0070","doi-asserted-by":"crossref","first-page":"2816","DOI":"10.1128\/JCM.00773-06","article-title":"Epidemiology of candidemia in Brazil: a nationwide sentinel surveillance of candidemia in eleven medical centers","volume":"44","author":"Colombo","year":"2006","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.riam.2013.05.007_bib0075","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0732-8893(99)00042-5","article-title":"High rate of non-albicans candidemia in Brazilian tertiary care hospitals","volume":"34","author":"Colombo","year":"1999","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0080","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1007\/s10096-003-0973-8","article-title":"Global distribution and outcomes for Candida species causing invasive candidiasis: results from an international randomized double-blind study of caspofungin versus amphotericin B for the treatment of invasive candidiasis","volume":"22","author":"Colombo","year":"2003","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0085","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1056\/NEJMoa061094","article-title":"Posaconazole vs. fluconazole or itraconazole prophylaxis in patients with neutropenia","volume":"356","author":"Cornely","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1016\/j.riam.2013.05.007_bib0090","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1053\/jhin.1999.0670","article-title":"Nosocomial fungaemia: a 2-year prospective study","volume":"45","author":"Costa","year":"2000","journal-title":"J Hosp Infect"},{"key":"10.1016\/j.riam.2013.05.007_bib0095","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1007\/s00134-005-2794-y","article-title":"Prophylaxis of Candida infections in adult trauma and surgical intensive care patients: a systematic review and meta-analysis","volume":"31","author":"Cruciani","year":"2005","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.riam.2013.05.007_bib0100","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1093\/jac\/dkf060","article-title":"Antifungal susceptibilities of Candida spp. isolated from blood in Spain and Argentina, 1996\u20131999","volume":"49","author":"Cuenca-Estrella","year":"2002","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.riam.2013.05.007_bib0105","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.diagmicrobio.2006.10.011","article-title":"Antifungal susceptibility of 1000 Candida bloodstream isolates to 5 antifungal drugs: results of a multicenter study conducted in Sao Paulo, Brazil, 1995\u20132003","volume":"57","author":"da Matta","year":"2007","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0110","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1097\/00003246-199906000-00019","article-title":"Fluconazole prophylaxis prevents intra-abdominal candidiasis in high-risk surgical patients","volume":"27","author":"Eggimann","year":"1999","journal-title":"Crit Care Med"},{"key":"10.1016\/j.riam.2013.05.007_bib0115","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S0163-4453(97)91347-5","article-title":"Fungal endocarditis","volume":"35","author":"Ellis","year":"1997","journal-title":"J Infect"},{"key":"10.1016\/j.riam.2013.05.007_bib0120","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1086\/317550","article-title":"Fungal endocarditis: evidence in the world literature, 1965\u20131995","volume":"32","author":"Ellis","year":"2001","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0125","first-page":"99","article-title":"Outcome of treatment of candidemia in children whose central catheters were removed or retained","volume":"8","author":"Eppes","year":"1989","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.riam.2013.05.007_bib0130","series-title":"Antibiotic and chemotherapy: anti-infective agents and their use in therapy","author":"Finch","year":"2003"},{"key":"10.1016\/j.riam.2013.05.007_bib0135","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1128\/AAC.33.9.1443","article-title":"Comparison of in vivo activity of fluconazole with that of amphotericin B against Candida tropicalis, Candida glabrata, and Candida krusei","volume":"33","author":"Fisher","year":"1989","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.riam.2013.05.007_bib0140","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.4065\/83.9.1011","article-title":"Treatment of invasive candidal infections: systematic review and meta-analysis","volume":"83","author":"Gafter-Gvili","year":"2008","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.riam.2013.05.007_bib0145","series-title":"Program and abstracts of the 9th International Congress on Infectious Diseases","article-title":"Prevention of severe Candida infections in nonneutropenic, high-risk, critically ill patients: a randomized, double-blind, placebo-controlled trial","author":"Garbino","year":"2000"},{"key":"10.1016\/j.riam.2013.05.007_bib0150","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1086\/504810","article-title":"Time to initiation of fluconazole therapy impacts mortality in patients with candidemia: a multi-institutional study","volume":"43","author":"Garey","year":"2006","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0155","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1056\/NEJM199203263261301","article-title":"A controlled trial of fluconazole to prevent fungal infections in patients undergoing bone marrow transplantation","volume":"326","author":"Goodman","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1016\/j.riam.2013.05.007_bib0160","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1093\/infdis\/164.4.731","article-title":"Clinical features and analysis of risk factors for invasive candidal infection after marrow transplantation","volume":"164","author":"Goodrich","year":"1991","journal-title":"J Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0165","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1128\/JCM.42.4.1519-1527.2004","article-title":"Incidence of bloodstream infections due to Candida species and in vitro susceptibilities of isolates collected from 1998 to 2000 in a population-based active surveillance program","volume":"42","author":"Hajjeh","year":"2004","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.riam.2013.05.007_bib0170","doi-asserted-by":"crossref","first-page":"R710","DOI":"10.1186\/cc3883","article-title":"The use of prophylactic fluconazole in immunocompetent high-risk surgical patients: a meta-analysis","volume":"9","author":"Ho","year":"2005","journal-title":"Crit Care"},{"key":"10.1016\/j.riam.2013.05.007_bib0175","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1093\/clinids\/20.6.1526","article-title":"Epidemiology of nosocomial fungal infections, with emphasis on Candida species","volume":"20","author":"Jarvis","year":"1995","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0180","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1086\/313450","article-title":"The epidemiology of candidemia in two United States cities: results of a population-based active surveillance","volume":"29","author":"Kao","year":"1999","journal-title":"Clin Infect Dis"},{"issue":"Pt 1","key":"10.1016\/j.riam.2013.05.007_bib0185","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1038\/eye.2000.7","article-title":"Should all patients with candidaemia have an ophthalmic examination to rule out ocular candidiasis?","volume":"14","author":"Krishna","year":"2000","journal-title":"Eye (Lond)"},{"key":"10.1016\/j.riam.2013.05.007_bib0190","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1128\/AAC.46.6.1773-1780.2002","article-title":"Antifungal susceptibility of Candida biofilms: unique efficacy of amphotericin B lipid formulations and echinocandins","volume":"46","author":"Kuhn","year":"2002","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.riam.2013.05.007_bib0195","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1016\/S0140-6736(07)60605-9","article-title":"Micafungin versus liposomal amphotericin B for candidaemia and invasive candidosis: a phase III randomised double-blind trial","volume":"369","author":"Kuse","year":"2007","journal-title":"Lancet"},{"key":"10.1016\/j.riam.2013.05.007_bib0200","doi-asserted-by":"crossref","first-page":"3546","DOI":"10.1128\/JCM.01555-07","article-title":"Detection of bloodstream infections in adults: how many blood cultures are needed?","volume":"45","author":"Lee","year":"2007","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.riam.2013.05.007_bib0205","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1086\/527390","article-title":"Adjuvant corticosteroid therapy for chronic disseminated candidiasis","volume":"46","author":"Legrand","year":"2008","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0210","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1097\/01.CCM.0000202208.37364.7D","article-title":"A bedside scoring system (\u201cCandida score\u201d) for early antifungal treatment in nonneutropenic critically ill patients with Candida colonization","volume":"34","author":"Leon","year":"2006","journal-title":"Crit Care Med"},{"key":"10.1016\/j.riam.2013.05.007_bib0215","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1097\/CCM.0b013e31819daa14","article-title":"Usefulness of the \u201cCandida score\u201d for discriminating between Candida colonization and invasive candidiasis in non-neutropenic critically ill patients: a prospective multicenter study","volume":"37","author":"Leon","year":"2009","journal-title":"Crit Care Med"},{"key":"10.1016\/j.riam.2013.05.007_bib0220","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1007\/s100960000325","article-title":"Nosocomial candidemia in non-neutropenic patients at an Italian tertiary care hospital","volume":"19","author":"Luzzati","year":"2000","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0225","doi-asserted-by":"crossref","first-page":"325","DOI":"10.3324\/haematol.2012.061952","article-title":"The role of antifungal treatment in hematology","volume":"97","author":"Maertens","year":"2012","journal-title":"Haematologica"},{"key":"10.1016\/j.riam.2013.05.007_bib0230","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1517\/14656566.2.11.1849","article-title":"Pharmacotherapy of fungal eye infections","volume":"2","author":"Manzouri","year":"2001","journal-title":"Expert Opin Pharmacother"},{"key":"10.1016\/j.riam.2013.05.007_bib0235","doi-asserted-by":"crossref","first-page":"2055","DOI":"10.1182\/blood.V96.6.2055","article-title":"Prolonged fluconazole prophylaxis is associated with persistent protection against candidiasis-related death in allogeneic marrow transplant recipients: long-term follow-up of a randomized, placebo-controlled trial","volume":"96","author":"Marr","year":"2000","journal-title":"Blood"},{"key":"10.1016\/j.riam.2013.05.007_bib0240","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1086\/315193","article-title":"Candidemia in allogeneic blood and marrow transplant recipients: evolution of risk factors after the adoption of prophylactic fluconazole","volume":"181","author":"Marr","year":"2000","journal-title":"J Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0245","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.leukres.2004.10.003","article-title":"Chronic disseminated candidiasis in patients with acute leukemia: emphasis on diagnostic definition and treatment","volume":"29","author":"Masood","year":"2005","journal-title":"Leuk Res"},{"key":"10.1016\/j.riam.2013.05.007_bib0250","unstructured":"Merck. CANCIDAS (caspofungin acetate). Product Information. November 2010."},{"key":"10.1016\/j.riam.2013.05.007_bib0255","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1086\/599376","article-title":"Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society of America","volume":"49","author":"Mermel","year":"2009","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0260","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0002-9343(97)90050-4","article-title":"Incidence and risk of developing fungal prosthetic valve endocarditis after nosocomial candidemia","volume":"103","author":"Nasser","year":"1997","journal-title":"Am J Med"},{"key":"10.1016\/j.riam.2013.05.007_bib0265","doi-asserted-by":"crossref","first-page":"1906","DOI":"10.1093\/jac\/dkr186","article-title":"Cost-effectiveness analysis of anidulafungin versus fluconazole for the treatment of invasive candidiasis","volume":"66","author":"Neoh","year":"2011","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.riam.2013.05.007_bib0270","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1093\/clinids\/22.2.262","article-title":"Candida prosthetic valve endocarditis: prospective study of six cases and review of the literature","volume":"22","author":"Nguyen","year":"1996","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0275","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1111\/j.1600-0609.2008.01041.x","article-title":"Effect of fluconazole prophylaxis on the incidence of invasive Candida infections and bacteraemias in patients with acute leukaemia","volume":"80","author":"Nihtinen","year":"2008","journal-title":"Eur J Haematol"},{"key":"10.1016\/j.riam.2013.05.007_bib0280","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s12281-010-0039-1","article-title":"Persistent candidemia: causes and investigations","volume":"5","author":"Nucci","year":"2011","journal-title":"Curr Fungal Infect Rep"},{"key":"10.1016\/j.riam.2013.05.007_bib0285","series-title":"50th Interscience Conference on Antimicrobial Agents and Chemotherapy","article-title":"Epidemiology of candidemia in Latin America: Preliminary results of a prospective laboratory-based survey","author":"Nucci","year":"2010"},{"key":"10.1016\/j.riam.2013.05.007_bib0290","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1086\/653935","article-title":"Early removal of central venous catheter in patients with candidemia does not improve outcome: analysis of 842 patients from 2 randomized clinical trials","volume":"51","author":"Nucci","year":"2010","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0295","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s10096-002-0697-1","article-title":"Risk factors for breakthrough candidemia","volume":"21","author":"Nucci","year":"2002","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0300","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1086\/647743","article-title":"Risk factors for death in patients with candidemia","volume":"19","author":"Nucci","year":"1998","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.riam.2013.05.007_bib0305","series-title":"21st European Congress of Clinical Microbiology and Infectious Diseases\/27th international congress of chemotherapy","article-title":"open-label study of intravenous anidulafungin followed optionally by oral voriconazole for treatment of candidaemia\/invasive candidiasis in critically ill patients","author":"Nucci","year":"2011"},{"key":"10.1016\/j.riam.2013.05.007_bib0310","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1086\/655683","article-title":"Epidemiology of opportunistic fungal infections in Latin America","volume":"51","author":"Nucci","year":"2010","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0315","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1086\/514609","article-title":"Risk factors for death among cancer patients with fungemia","volume":"27","author":"Nucci","year":"1998","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0320","doi-asserted-by":"crossref","first-page":"113","DOI":"10.3109\/13693786.2010.512300","article-title":"Early treatment of candidemia in adults: a review","volume":"49","author":"Ostrosky-Zeichner","year":"2011","journal-title":"Med Mycol"},{"key":"10.1016\/j.riam.2013.05.007_bib0325","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/s10096-007-0270-z","article-title":"Multicenter retrospective development and validation of a clinical prediction rule for nosocomial invasive candidiasis in the intensive care setting","volume":"26","author":"Ostrosky-Zeichner","year":"2007","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0330","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1128\/JCM.44.5.1740-1743.2006","article-title":"Clinical significance of azole antifungal drug cross-resistance in Candida glabrata","volume":"44","author":"Panackal","year":"2006","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.riam.2013.05.007_bib0335","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1086\/596757","article-title":"Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America","volume":"48","author":"Pappas","year":"2009","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0340","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1086\/376906","article-title":"A prospective observational study of candidemia: epidemiology, therapy, and influences on mortality in hospitalized adult and pediatric patients","volume":"37","author":"Pappas","year":"2003","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0345","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1086\/380796","article-title":"Guidelines for treatment of candidiasis","volume":"38","author":"Pappas","year":"2004","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0350","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1159\/000315558","article-title":"Efficacy and safety of micafungin as an empirical antifungal agent for febrile neutropenic patients with hematological diseases","volume":"124","author":"Park","year":"2010","journal-title":"Acta Haematol"},{"key":"10.1016\/j.riam.2013.05.007_bib0355","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1086\/590191","article-title":"Take control over your fluconazole prescriptions: the growing importance of Candida glabrata as an agent of candidemia in Brazil","volume":"29","author":"Pasqualotto","year":"2008","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"Suppl","key":"10.1016\/j.riam.2013.05.007_bib0360","first-page":"A33","article-title":"A double-blind placebo controlled trial of prophylactic fluconazole to prevent Candida infections in critically ill surgical patients","volume":"27","author":"Pelz","year":"2000","journal-title":"Crit Care Med"},{"key":"10.1016\/j.riam.2013.05.007_bib0365","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1128\/JCM.44.3.760-763.2006","article-title":"In vitro susceptibilities of Candida spp. to caspofungin: four years of global surveillance","volume":"44","author":"Pfaller","year":"2006","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.riam.2013.05.007_bib0370","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1128\/CMR.00029-06","article-title":"Epidemiology of invasive candidiasis: a persistent public health problem","volume":"20","author":"Pfaller","year":"2007","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.riam.2013.05.007_bib0375","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1128\/JCM.01915-07","article-title":"Candida krusei, a multidrug-resistant opportunistic fungal pathogen: geographic and temporal trends from the ARTEMIS DISK Antifungal Surveillance Program, 2001 to 2005","volume":"46","author":"Pfaller","year":"2008","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.riam.2013.05.007_bib0380","doi-asserted-by":"crossref","first-page":"5848","DOI":"10.1128\/JCM.43.12.5848-5859.2005","article-title":"Results from the ARTEMIS DISK Global Antifungal Surveillance Study: a 6.5-year analysis of susceptibilities of Candida and other yeast species to fluconazole and voriconazole by standardized disk diffusion testing","volume":"43","author":"Pfaller","year":"2005","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.riam.2013.05.007_bib0385","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1128\/JCM.02441-10","volume":"49","author":"Pfaller","year":"2011","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.riam.2013.05.007_bib0390","unstructured":"Pfizer. ERAXIS (anidulafungin) for injection. Product Information. Revised November 2010."},{"key":"10.1016\/j.riam.2013.05.007_bib0395","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1097\/00000658-199412000-00008","article-title":"Candida colonization and subsequent infections in critically ill surgical patients","volume":"220","author":"Pittet","year":"1994","journal-title":"Ann Surg"},{"key":"10.1016\/j.riam.2013.05.007_bib0400","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1001\/archinte.1995.00430110089009","article-title":"Nosocomial bloodstream infections. Secular trends in rates, mortality, and contribution to total hospital deaths","volume":"155","author":"Pittet","year":"1995","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.riam.2013.05.007_bib0405","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1093\/jac\/dki491","article-title":"Antifungal agents for preventing fungal infections in non-neutropenic critically ill and surgical patients: systematic review and meta-analysis of randomized clinical trials","volume":"57","author":"Playford","year":"2006","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.riam.2013.05.007_bib0410","doi-asserted-by":"crossref","first-page":"R249","DOI":"10.1186\/cc10507","article-title":"Early diagnosis of candidemia in intensive care unit patients with sepsis: a prospective comparison of (1\u21923)-beta-d-glucan assay, Candida score, and colonization index","volume":"15","author":"Posteraro","year":"2011","journal-title":"Crit Care"},{"key":"10.1016\/j.riam.2013.05.007_bib0415","doi-asserted-by":"crossref","first-page":"2472","DOI":"10.1056\/NEJMoa066906","article-title":"Anidulafungin versus fluconazole for invasive candidiasis","volume":"356","author":"Reboli","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1016\/j.riam.2013.05.007_bib0420","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1093\/clinids\/21.4.994","article-title":"Intravascular catheter exchange and duration of candidemia","volume":"21","author":"Rex","year":"1995","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0425","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1086\/319763","article-title":"Prophylactic antifungal therapy in the intensive care unit","volume":"32","author":"Rex","year":"2001","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0430","series-title":"Fungal infection: diagnosis and management","first-page":"12","article-title":"Laboratory diagnosis of fungal infection","author":"Richardson","year":"2012"},{"key":"10.1016\/j.riam.2013.05.007_bib0435","first-page":"114","article-title":"Multicenter study on nosocomial candidiasis in the Republic of Argentina","volume":"31","author":"Rodero","year":"1999","journal-title":"Rev Argent Microbiol"},{"key":"10.1016\/j.riam.2013.05.007_bib0440","first-page":"189","article-title":"Multicenter study of fungemia due to yeasts in Argentina","volume":"37","author":"Rodero","year":"2005","journal-title":"Rev Argent Microbiol"},{"key":"10.1016\/j.riam.2013.05.007_bib0445","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.2165\/00003495-200868140-00002","article-title":"Patients at high risk of invasive fungal infections: when and how to treat","volume":"68","author":"Ruping","year":"2008","journal-title":"Drugs"},{"key":"10.1016\/j.riam.2013.05.007_bib0450","doi-asserted-by":"crossref","first-page":"1928","DOI":"10.1097\/01.CCM.0000178352.14703.49","article-title":"Fluconazole prophylaxis in critically ill surgical patients: a meta-analysis","volume":"33","author":"Shorr","year":"2005","journal-title":"Crit Care Med"},{"key":"10.1016\/j.riam.2013.05.007_bib0455","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1080\/13693780410001657153","article-title":"Invasive fungal infections in Chile: a multicenter study of fungal prevalence and susceptibility during a 1-year period","volume":"42","author":"Silva","year":"2004","journal-title":"Med Mycol"},{"key":"10.1016\/j.riam.2013.05.007_bib0460","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1093\/infdis\/171.6.1545","article-title":"Efficacy and safety of fluconazole prophylaxis for fungal infections after marrow transplantation \u2013 a prospective, randomized, double-blind study","volume":"171","author":"Slavin","year":"1995","journal-title":"J Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0465","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/s10096-004-1103-y","article-title":"Epidemiology of candidaemia in Europe: results of 28-month European Confederation of Medical Mycology (ECMM) hospital-based surveillance study","volume":"23","author":"Tortorano","year":"2004","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0470","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1086\/342300","article-title":"Secular trend of hospital-acquired candidemia among intensive care unit patients in the United States during 1989\u20131999","volume":"35","author":"Trick","year":"2002","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0475","series-title":"University of Pennsylvania Medical Center Guidelines for blood culture collection","author":"University of Pennsylvania Medical Center","year":"2011"},{"key":"10.1016\/j.riam.2013.05.007_bib0480","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1086\/422312","article-title":"Micafungin versus fluconazole for prophylaxis against invasive fungal infections during neutropenia in patients undergoing hematopoietic stem cell transplantation","volume":"39","author":"van Burik","year":"2004","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0485","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1097\/01.CCM.0000208357.05675.C3","article-title":"Antifungal prophylaxis with azoles in high-risk, surgical intensive care unit patients: a meta-analysis of randomized, placebo-controlled trials","volume":"34","author":"Vardakas","year":"2006","journal-title":"Crit Care Med"},{"key":"10.1016\/j.riam.2013.05.007_bib0490","series-title":"21st European Congress of Clinical Microbiology and Infectious Diseases\/27th international congress of chemotherapy","article-title":"A phase IV, open-label study evaluating efficacy and safety of intravenous anidulafungin followed by oral azole for the treatment of candidaemia\/invasive candidiasis in US\/Korean patients","author":"Vazquez","year":"2011"},{"key":"10.1016\/j.riam.2013.05.007_bib0495","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1086\/514731","article-title":"Candidemia in cancer patients: a prospective, multicenter surveillance study by the Invasive Fungal Infection Group (IFIG) of the European Organization for Research and Treatment of Cancer (EORTC)","volume":"28","author":"Viscoli","year":"1999","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0500","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1056\/NEJM199903113401004","article-title":"Liposomal amphotericin B for empirical therapy in patients with persistent fever and neutropenia","volume":"340","author":"Walsh","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.riam.2013.05.007_bib0505","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1056\/NEJM200201243460403","article-title":"Voriconazole compared with liposomal amphotericin B for empirical antifungal therapy in patients with neutropenia and persistent fever","volume":"346","author":"Walsh","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.riam.2013.05.007_bib0510","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1056\/NEJMoa040446","article-title":"Caspofungin versus liposomal amphotericin B for empirical antifungal therapy in patients with persistent fever and neutropenia","volume":"351","author":"Walsh","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.riam.2013.05.007_bib0515","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.jhin.2005.02.009","article-title":"Characteristics of candidaemia with Candida albicans compared with non-albicans Candida species and predictors of mortality","volume":"61","author":"Weinberger","year":"2005","journal-title":"J Hosp Infect"},{"key":"10.1016\/j.riam.2013.05.007_bib0520","series-title":"Lippincott's nursing procedures","first-page":"187","article-title":"Specimen collection and testing","author":"Wilkins","year":"2009"},{"key":"10.1016\/j.riam.2013.05.007_bib0525","doi-asserted-by":"crossref","first-page":"5111","DOI":"10.1182\/blood-2010-02-268151","article-title":"Randomized, double-blind trial of fluconazole versus voriconazole for prevention of invasive fungal infection after allogeneic hematopoietic cell transplantation","volume":"116","author":"Wingard","year":"2010","journal-title":"Blood"},{"key":"10.1016\/j.riam.2013.05.007_bib0530","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1086\/317451","article-title":"A randomized, double-blind comparative trial evaluating the safety of liposomal amphotericin B versus amphotericin B lipid complex in the empirical treatment of febrile neutropenia","volume":"31","author":"Wingard","year":"2000","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0535","doi-asserted-by":"crossref","first-page":"495","DOI":"10.7326\/0003-4819-118-7-199304010-00003","article-title":"Fluconazole prophylaxis of fungal infections in patients with acute leukemia. Results of a randomized placebo-controlled, double-blind, multicenter trial","volume":"118","author":"Winston","year":"1993","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.riam.2013.05.007_bib0540","doi-asserted-by":"crossref","first-page":"705","DOI":"10.7326\/0003-4819-138-9-200305060-00006","article-title":"Intravenous and oral itraconazole versus intravenous and oral fluconazole for long-term antifungal prophylaxis in allogeneic hematopoietic stem-cell transplant recipients. A multicenter, randomized trial","volume":"138","author":"Winston","year":"2003","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.riam.2013.05.007_bib0545","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1086\/421946","article-title":"Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study","volume":"39","author":"Wisplinghoff","year":"2004","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.riam.2013.05.007_bib0550","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1086\/374339","article-title":"Current trends in the epidemiology of nosocomial bloodstream infections in patients with hematological malignancies and solid neoplasms in hospitals in the United States","volume":"36","author":"Wisplinghoff","year":"2003","journal-title":"Clin Infect Dis"}],"container-title":["Revista Iberoamericana de Micolog\u00eda"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S113014061300051X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S113014061300051X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T04:06:19Z","timestamp":1761105979000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S113014061300051X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7]]},"references-count":110,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["S113014061300051X"],"URL":"https:\/\/doi.org\/10.1016\/j.riam.2013.05.007","relation":{},"ISSN":["1130-1406"],"issn-type":[{"value":"1130-1406","type":"print"}],"subject":[],"published":{"date-parts":[[2013,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Recommendations for the management of candidemia in adults in Latin America","name":"articletitle","label":"Article Title"},{"value":"Revista Iberoamericana de Micolog\u00eda","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.riam.2013.05.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Revista Iberoamericana de Micolog\u00eda. Published by Elsevier Espa\u00f1a, S.L. All rights reserved.","name":"copyright","label":"Copyright"}]}}