{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T13:46:28Z","timestamp":1791294388047,"version":"4.1.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2009,7,1]],"date-time":"2009-07-01T00:00:00Z","timestamp":1246406400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Research in Developmental Disabilities"],"published-print":{"date-parts":[[2009,7]]},"DOI":"10.1016\/j.ridd.2008.10.007","type":"journal-article","created":{"date-parts":[[2008,12,14]],"date-time":"2008-12-14T04:36:12Z","timestamp":1229229372000},"page":"763-773","source":"Crossref","is-referenced-by-count":199,"title":["Autism, ADHD, mental retardation and behavior problems in 100 individuals with 22q11 deletion syndrome"],"prefix":"10.1016","volume":"30","author":[{"given":"Lena","family":"Niklasson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peder","family":"Rasmussen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00f3lveig","family":"\u00d3skarsd\u00f3ttir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Gillberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ridd.2008.10.007_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2307\/1166156","article-title":"National survey of problems and competencies among four- to sixteen-year-olds: Parents\u2019 reports for normative and clinical samples","volume":"56","author":"Achenbach","year":"1991","journal-title":"Monographs of the Society for Research in Child Development"},{"key":"10.1016\/j.ridd.2008.10.007_bib2","series-title":"Griffiths Utvecklinsskalor","author":"Ahlin-\u00c5kerman","year":"1980"},{"key":"10.1016\/j.ridd.2008.10.007_bib3","doi-asserted-by":"crossref","first-page":"1776","DOI":"10.1007\/s10803-006-0308-6","article-title":"Autistic spectrum disorders in velo-cardio facial syndrome (22q11.2 deletion)","volume":"37","author":"Antshel","year":"2007","journal-title":"Journal of Autism and Developmental Disorders"},{"key":"10.1016\/j.ridd.2008.10.007_bib4","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1097\/01.chi.0000205703.25453.5a","article-title":"ADHD, major depressive disorder, and simple phobias are prevalent psychiatric conditions in youth with velocardiofacial syndrome","volume":"45","author":"Antshel","year":"2006","journal-title":"Journal of the American Academy of Child and Adolescent Psychiatry"},{"key":"10.1016\/j.ridd.2008.10.007_bib5","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1192\/bjp.186.2.115","article-title":"Adolescents and young adults with 22q11 deletion syndrome: Psychopathology in an at-risk group","volume":"186","author":"Baker","year":"2005","journal-title":"British Journal of Psychiatry"},{"key":"10.1016\/j.ridd.2008.10.007_bib6","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1023\/A:1022602400621","article-title":"The revised Conners\u2019 Parent Rating Scale (CPRS-R): Factor structure, reliability, and criterion validity","volume":"26","author":"Conners","year":"1998","journal-title":"Journal of Abnormal Child Psychology"},{"key":"10.1016\/j.ridd.2008.10.007_bib7","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1111\/j.1365-2788.2007.00955.x","article-title":"Intellectual abilities in a large sample of children with velo-cardio-facial syndrome: An update","volume":"51","author":"De Smedt","year":"2007","journal-title":"Journal of Intellectual Disability Research"},{"key":"10.1016\/j.ridd.2008.10.007_bib8","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1034\/j.1399-0004.2003.00049.x","article-title":"Spectrum of clinical variability in familial deletion 22q11.2: From full manifestation to extremely mild clinical anomalies","volume":"63","author":"Digilio","year":"2003","journal-title":"Clinical Genetics"},{"key":"10.1016\/j.ridd.2008.10.007_bib9","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1002\/ajmg.1320440237","article-title":"Deletions and microdeletions of 22q11.2 in velo-cardio-facial syndrome","volume":"44","author":"Driscoll","year":"1992","journal-title":"American Journal of Medical Genetics"},{"key":"10.1016\/j.ridd.2008.10.007_bib10","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1111\/j.1469-7610.1993.tb02094.x","article-title":"The epidemiology of Asperger syndrome. A total population study","volume":"34","author":"Ehlers","year":"1993","journal-title":"Journal of Child Psychology and Psychiatry and Allied Disciplines"},{"key":"10.1016\/j.ridd.2008.10.007_bib11","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1023\/A:1023040610384","article-title":"A screening questionnaire for Asperger syndrome and other high-functioning autism spectrum disorders in school age children","volume":"29","author":"Ehlers","year":"1999","journal-title":"Journal of Autism and Developmental Disorders"},{"key":"10.1016\/j.ridd.2008.10.007_bib12","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1007\/s10803-005-5036-9","article-title":"Autism spectrum disorders and symptoms in children with molecularly confirmed 22q11.2 deletion syndrome","volume":"35","author":"Fine","year":"2005","journal-title":"Journal of Autism and Developmental Disorders"},{"key":"10.1016\/j.ridd.2008.10.007_bib13","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1002\/(SICI)1096-8628(19990716)85:2<127::AID-AJMG6>3.0.CO;2-F","article-title":"Cognitive and behavior profile of preschool children with chromosome 22q11.2 deletion","volume":"85","author":"Gerdes","year":"1999","journal-title":"American Journal of Medical Genetics"},{"key":"10.1016\/j.ridd.2008.10.007_bib14","series-title":"Autism and Asperger syndrome","first-page":"122","article-title":"Clinical and neurobiological aspects of Asperger syndrome in six family studies","author":"Gillberg","year":"1991"},{"key":"10.1016\/j.ridd.2008.10.007_bib15","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1002\/ajmg.b.20144","article-title":"Genetic, developmental, and physical factors associated with attention deficit hyperactivity disorder in patients with velocardiofacial syndrome","volume":"126","author":"Gothelf","year":"2004","journal-title":"American Journal of Medical Genetics Part B"},{"issue":"Suppl. 3","key":"10.1016\/j.ridd.2008.10.007_bib16","first-page":"3","article-title":"The FTF (five to fifteen): The development of a parent questionnaire for the assessment of ADHD and comorbid conditions","volume":"13","author":"Kadesjo","year":"2004","journal-title":"European Child and Adolescent Psychiatry"},{"key":"10.1016\/j.ridd.2008.10.007_bib17","doi-asserted-by":"crossref","first-page":"2642","DOI":"10.1002\/ajmg.a.32012","article-title":"Comparing phenotypes in patients with idiopathic autism to patients with velocardiofacial syndrome (22q11 DS) with and without autism","volume":"143","author":"Kates","year":"2007","journal-title":"American Journal of Medical Genetics Part A"},{"key":"10.1016\/j.ridd.2008.10.007_bib18","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1007\/s007870050080","article-title":"Social competence and emotional\/behaviour problems in 6\u201316 year-old Swedish school children","volume":"8","author":"Larsson","year":"1999","journal-title":"European Child and Adolescent Psychiatry"},{"key":"10.1016\/j.ridd.2008.10.007_bib19","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1007\/BF02172145","article-title":"Autism diagnostic interview-revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders","volume":"24","author":"Lord","year":"1994","journal-title":"Journal of Autism and Developmental Disorders"},{"key":"10.1016\/j.ridd.2008.10.007_bib20","first-page":"11","article-title":"The Philadelphia story: The 22q11.2 deletion: Report on 250 patients","volume":"10","author":"McDonald-McGinn","year":"1999","journal-title":"Genetic Counseling"},{"key":"10.1016\/j.ridd.2008.10.007_bib21","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0022-3476(99)70415-4","article-title":"Psychoeducational profile of the 22q11.2 microdeletion: A complex pattern","volume":"134","author":"Moss","year":"1999","journal-title":"Journal of Pediatrics"},{"key":"10.1016\/j.ridd.2008.10.007_bib22","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1001\/archpsyc.56.10.940","article-title":"High rates of schizophrenia in adults with velo-cardio-facial syndrome","volume":"56","author":"Murphy","year":"1999","journal-title":"Archives of General Psychiatry"},{"key":"10.1016\/j.ridd.2008.10.007_bib23","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1097\/00125817-200101000-00017","article-title":"Neuropsychiatric disorders in the 22q11 deletion syndrome","volume":"3","author":"Niklasson","year":"2001","journal-title":"Genetics in Medicine"},{"key":"10.1016\/j.ridd.2008.10.007_bib24","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1017\/S0012162201001645","article-title":"Chromosome 22q11 deletion syndrome (CATCH 22): Neuropsychiatric and neuropsychological aspects","volume":"44","author":"Niklasson","year":"2002","journal-title":"Developmental Medicine and Child Neurology"},{"key":"10.1016\/j.ridd.2008.10.007_bib25","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1017\/S0012162205000320","article-title":"Disabilities and cognition in children and adolescents with 22q11 deletion syndrome","volume":"47","author":"Oskarsdottir","year":"2005","journal-title":"Developmental Medicine and Child Neurology"},{"key":"10.1016\/j.ridd.2008.10.007_bib26","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1007\/s00431-004-1577-8","article-title":"Presenting phenotype in 100 children with the 22q11 deletion syndrome","volume":"164","author":"Oskarsdottir","year":"2005","journal-title":"European Journal of Pediatrics"},{"key":"10.1016\/j.ridd.2008.10.007_bib27","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1136\/adc.2003.026880","article-title":"Incidence and prevalence of the 22q11 deletion syndrome: A population-based study in Western Sweden","volume":"89","author":"Oskarsdottir","year":"2004","journal-title":"Archives of Disease in Childhood"},{"key":"10.1016\/j.ridd.2008.10.007_bib28","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1176\/ajp.153.12.1541","article-title":"Bipolar spectrum disorders in patients diagnosed with velo-cardio-facial syndrome: Does a hemizygous deletion of chromosome 22q11 result in bipolar affective disorder?","volume":"153","author":"Papolos","year":"1996","journal-title":"American Journal of Psychiatry"},{"key":"10.1016\/j.ridd.2008.10.007_bib29","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1080\/13682820500361497","article-title":"Language skills in 5\u20138-year-old children with 22q11 deletion syndrome","volume":"41","author":"Persson","year":"2006","journal-title":"International Journal of Language and Communication Disorders"},{"key":"10.1016\/j.ridd.2008.10.007_bib30","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1111\/j.1469-7610.2005.01462.x","article-title":"Autistic features in a total population of 7\u20139-year-old children assessed by the ASSQ (Autism Spectrum Screening Questionnaire)","volume":"47","author":"Posserud","year":"2006","journal-title":"Journal of Child Psychology and Psychiatry and Allied Disciplines"},{"key":"10.1016\/j.ridd.2008.10.007_bib31","series-title":"Vineland adaptive behaviour scales","author":"Sparrow","year":"1984"},{"key":"10.1016\/j.ridd.2008.10.007_bib32","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1136\/jmg.34.6.453","article-title":"Intelligence and psychosocial adjustment in velocardiofacial syndrome: A study of 37 children and adolescents with VCFS","volume":"34","author":"Swillen","year":"1997","journal-title":"Journal of Medical Genetics"},{"key":"10.1016\/j.ridd.2008.10.007_bib33","first-page":"79","article-title":"The behavioural phenotype in velo-cardio-facial syndrome (VCFS): From infancy to adolescence","volume":"10","author":"Swillen","year":"1999","journal-title":"Genetic Counseling"},{"key":"10.1016\/j.ridd.2008.10.007_bib34","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1097\/01.chi.0000228131.56956.c1","article-title":"The 22q11.2 deletion in children: High rate of autistic disorders and early onset of psychotic symptoms","volume":"45","author":"Vorstman","year":"2006","journal-title":"Journal of the American Academy of Child and Adolescent Psychiatry"},{"key":"10.1016\/j.ridd.2008.10.007_bib35","series-title":"Manual of the Wechsler adult intelligence scale \u2013 revised","author":"Wechsler","year":"1981"},{"key":"10.1016\/j.ridd.2008.10.007_bib36","series-title":"Wechsler preschool and primary scale of intelligence scale \u2013 revised","author":"Wechsler","year":"1989"},{"key":"10.1016\/j.ridd.2008.10.007_bib37","series-title":"Manual of the Wechsler intelligence scale for children, 3rd edition revised","author":"Wechsler","year":"1992"},{"key":"10.1016\/j.ridd.2008.10.007_bib38","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1111\/1469-7610.00023","article-title":"The Diagnostic interview for social and communication disorders: Background, inter-rater reliability and clinical use","volume":"43","author":"Wing","year":"2002","journal-title":"Journal of Child Psychology and Psychiatry and Allied Disciplines"}],"container-title":["Research in Developmental Disabilities"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S089142220800125X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S089142220800125X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,16]],"date-time":"2019-05-16T03:55:08Z","timestamp":1557978908000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S089142220800125X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,7]]},"references-count":38,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,7]]}},"alternative-id":["S089142220800125X"],"URL":"https:\/\/doi.org\/10.1016\/j.ridd.2008.10.007","relation":{},"ISSN":["0891-4222"],"issn-type":[{"value":"0891-4222","type":"print"}],"subject":[],"published":{"date-parts":[[2009,7]]}}}