{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T02:49:34Z","timestamp":1792464574382,"version":"4.5.0"},"reference-count":92,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,6,27]],"date-time":"2024-06-27T00:00:00Z","timestamp":1719446400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Research in Developmental Disabilities"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.ridd.2024.104788","type":"journal-article","created":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T22:46:05Z","timestamp":1720046765000},"page":"104788","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["An investigation of sleep problems, gastrointestinal symptoms, comorbid psychopathology and challenging behavior in children and adolescents with Down Syndrome"],"prefix":"10.1016","volume":"151","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9755-7152","authenticated-orcid":false,"given":"Arlene","family":"Mannion","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Neil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theresa","family":"Fiani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lindsay","family":"Athamanah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Lyons","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly","family":"McDonagh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin","family":"Boland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00f3is\u00edn","family":"Cooney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meagan","family":"Lynch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merna","family":"Youssef","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geraldine","family":"Leader","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.ridd.2024.104788_bib1","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1055\/s-0035-1550151","article-title":"Sleep in children with neurodevelopmental disabilities","volume":"46","author":"Angriman","year":"2015","journal-title":"Neuropediatrics"},{"issue":"3","key":"10.1016\/j.ridd.2024.104788_bib2","article-title":"The influence of sleep on language production modalities in preschool children with Down syndrome","volume":"30","author":"Arias\u2010Trejo","year":"2021","journal-title":"Journal of Sleeping Research"},{"issue":"1","key":"10.1016\/j.ridd.2024.104788_bib3","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/s12929-015-0138-y","article-title":"Down syndrome: An insight of the disease","volume":"22","author":"Asim","year":"2015","journal-title":"Journal of Biomedical Science"},{"key":"10.1016\/j.ridd.2024.104788_bib4","series-title":"GI Symptom Inventory Questionnaire, vers. 3.0","author":"Autism Treatment Network","year":"2005"},{"issue":"9","key":"10.1016\/j.ridd.2024.104788_bib5","first-page":"149","article-title":"Attention- deficit\/ hyperactivity disorder","volume":"114","author":"Banaschewski","year":"2017","journal-title":"Deutsches Arzteblatt International"},{"issue":"8","key":"10.1016\/j.ridd.2024.104788_bib6","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1002\/ajmg.a.37096","article-title":"Sleep profiles in children with Down syndrome","volume":"167","author":"Bassell","year":"2015","journal-title":"American Journal of Medical Genetics Part A"},{"issue":"1","key":"10.1016\/j.ridd.2024.104788_bib7","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1111\/bjc.12118","article-title":"Challenging behaviours in adults with an intellectual disability: A total population study and exploration of risk indices","volume":"56","author":"Bowring","year":"2017","journal-title":"British Journal of Clinical Psychology"},{"issue":"11","key":"10.1016\/j.ridd.2024.104788_bib8","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1111\/j.1365-2788.2011.01435.x","article-title":"Parental report of sleep problems in Down syndrome","volume":"55","author":"Breslin","year":"2011","journal-title":"Journal of Intellectual Disability Research"},{"issue":"7","key":"10.1016\/j.ridd.2024.104788_bib9","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1111\/dmcn.12376","article-title":"Obstructive sleep apnea syndrome and cognition in Down syndrome","volume":"56","author":"Breslin","year":"2014","journal-title":"Developmental Medicine & Child Neurology"},{"issue":"2","key":"10.1016\/j.ridd.2024.104788_bib10","first-page":"46","article-title":"A comparison of mainstream and special education for teenagers with Down syndrome: Implications for parents and teachers","volume":"2","author":"Buckley","year":"2002","journal-title":"Down Syndrome News and Update"},{"issue":"4","key":"10.1016\/j.ridd.2024.104788_bib11","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1136\/adc.2008.146845","article-title":"Sleep problems in a Down syndrome population","volume":"94","author":"Carter","year":"2008","journal-title":"Archives of Disease in Childhood"},{"issue":"4","key":"10.1016\/j.ridd.2024.104788_bib12","first-page":"191","article-title":"Thyroid dysfunction in patients with Down syndrome","volume":"48","author":"Chen","year":"2007","journal-title":"Acta Pediatrica Taiwanica"},{"issue":"1","key":"10.1016\/j.ridd.2024.104788_bib13","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1002\/wsbm.19","article-title":"Gastrointestinal system","volume":"2","author":"Cheng","year":"2014","journal-title":"Wiley Interdisciplinary Reviews Systems Biology and Medicine"},{"issue":"11","key":"10.1016\/j.ridd.2024.104788_bib14","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1111\/jir.12675","article-title":"Sleep problems in Korean children with Down syndrome and parental quality of life","volume":"63","author":"Choi","year":"2019","journal-title":"Journal of Intellectual Disability Research"},{"issue":"1","key":"10.1016\/j.ridd.2024.104788_bib15","doi-asserted-by":"crossref","first-page":"61","DOI":"10.5665\/sleep.4326","article-title":"Relationship between Sleep Disturbance and Functional Outcomes in Daily Life Habits of Children with Down Syndrome","volume":"38","author":"Churchill","year":"2015","journal-title":"Sleep"},{"issue":"2","key":"10.1016\/j.ridd.2024.104788_bib16","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1023\/A:1023044711293","article-title":"Behavior problems of children with Down syndrome and life events","volume":"29","author":"Coe","year":"1999","journal-title":"Journal of Autism and Developmental Disorders"},{"issue":"5","key":"10.1016\/j.ridd.2024.104788_bib17","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1016\/j.pcl.2008.07.001","article-title":"Primary care for children and adolescents with Down syndrome","volume":"55","author":"Davidson","year":"2008","journal-title":"Pediatric clinics of North America"},{"issue":"8","key":"10.1016\/j.ridd.2024.104788_bib18","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1097\/DBP.0000000000000179","article-title":"Psychotropic medication use in children and adolescents with Down syndrome","volume":"36","author":"Downes","year":"2015","journal-title":"Journal of Developmental & Behavioral Pediatrics"},{"issue":"3","key":"10.1016\/j.ridd.2024.104788_bib19","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1352\/0895-8017(1997)102<0228:MBICWP>2.0.CO;2","article-title":"Maladaptive behavior in children with Prader- Willi syndrome, Down syndrome, and nonspecific mental retardation","volume":"102","author":"Dykens","year":"1997","journal-title":"American Journal of Mental Retardation"},{"key":"10.1016\/j.ridd.2024.104788_bib20","doi-asserted-by":"crossref","unstructured":"Emerson, E. (2001). Challenging behaviour: Analysis and intervention in people with severe intellectual disabilities. Cambridge: Cambridge University Press.","DOI":"10.1017\/CBO9780511543739"},{"issue":"1","key":"10.1016\/j.ridd.2024.104788_bib21","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0891-4222(00)00061-5","article-title":"The prevalence of challenging behaviors: a total population study","volume":"22","author":"Emerson","year":"2001","journal-title":"Research in Developmental Disabilities"},{"key":"10.1016\/j.ridd.2024.104788_bib22","doi-asserted-by":"crossref","unstructured":"Ersoy, S.A., G\u00fcler, H.A., & \u00c7etin, F.H. (2018). Psychopathology in Down syndrome. In S. Dey (Ed.) Advances in Research on Down syndrome. InTechOpen. doi: 10.5772\/intechopen.71061.","DOI":"10.5772\/intechopen.71061"},{"issue":"3","key":"10.1016\/j.ridd.2024.104788_bib23","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1111\/jir.12315","article-title":"Reliability of parent report measures of sleep in children with Down syndrome","volume":"61","author":"Esbensen","year":"2017","journal-title":"Journal of Intellectual Disability Research"},{"issue":"2","key":"10.1016\/j.ridd.2024.104788_bib24","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1111\/jir.12463","article-title":"Links between sleep and daytime behaviour problems in children with Down syndrome","volume":"62","author":"Esbensen","year":"2018","journal-title":"Journal of Intellectual Disability Research"},{"issue":"6","key":"10.1016\/j.ridd.2024.104788_bib25","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1111\/jir.12496","article-title":"Impact of sleep on executive functioning in school-age children with Down syndrome","volume":"62","author":"Esbensen","year":"2018","journal-title":"Journal of Intellectual Disability Research"},{"issue":"4","key":"10.1016\/j.ridd.2024.104788_bib26","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1111\/jir.12464","article-title":"Convergent validity of actigraphy with polysomnography and parent reports when measuring sleep in children with Down syndrome","volume":"62","author":"Esbensen","year":"2018","journal-title":"Journal of Intellectual Disability Research"},{"key":"10.1016\/j.ridd.2024.104788_bib27","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1111\/1467-8624.00144","article-title":"Compulsive-like behavior in individuals with Down syndrome: Its relation to mental age level, adaptive and maladaptive behavior","volume":"71","author":"Evans","year":"2000","journal-title":"Child Development"},{"issue":"2","key":"10.1016\/j.ridd.2024.104788_bib28","doi-asserted-by":"crossref","first-page":"64","DOI":"10.3104\/perspectives.316","article-title":"Addressing challenging behaviour in children with Down syndrome: The use of applied behaviour analysis for assessment and intervention","volume":"11","author":"Feeley","year":"2006","journal-title":"Down Syndrome Research and Practice"},{"key":"10.1016\/j.ridd.2024.104788_bib29","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.sleep.2016.12.026","article-title":"Young children with Down syndrome show normal development of circadian rhythms, but poor sleep efficiency: A cross-sectional study across the first 60 months of life","volume":"33","author":"Fernandez","year":"2017","journal-title":"Sleeping Medicine"},{"issue":"6","key":"10.1016\/j.ridd.2024.104788_bib30","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1136\/adc.2004.049536","article-title":"Longitudinal study of thyroid function in Down\u2019s syndrome in the first two decades.","volume":"90","author":"Gibson","year":"2005","journal-title":"Archives of Disease in Childhood"},{"key":"10.1016\/j.ridd.2024.104788_bib31","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/j.rasd.2008.11.001","article-title":"Parental reports on the efficacy of treatments and therapies for their children with autism spectrum disorders","volume":"3","author":"Goin-Kochel","year":"2009","journal-title":"Research in Autism Spectrum Disorders"},{"key":"10.1016\/j.ridd.2024.104788_bib32","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1016\/j.rasd.2011.01.010","article-title":"Sleep is associated with problem behaviors in children and adolescents with Autism Spectrum Disorders","volume":"5","author":"Goldman","year":"2011","journal-title":"Research in Autism Spectrum Disorders"},{"key":"10.1016\/j.ridd.2024.104788_bib33","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1097\/DBP.0b013e318163c39a","article-title":"The children\u2019s sleep habits questionnaire in toddlers and pre-school children.","volume":"29","author":"Goodlin-Jones","year":"2008","journal-title":"Journal of Developmental and Behavioral Paediatrics"},{"issue":"2","key":"10.1016\/j.ridd.2024.104788_bib34","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1002\/aur.237","article-title":"Gastrointestinal dysfunction in autism: parental report, clinical evaluation, and associated factors","volume":"5","author":"Gorrindo","year":"2012","journal-title":"Autism Research"},{"issue":"2","key":"10.1016\/j.ridd.2024.104788_bib35","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1111\/j.1365-2788.1989.tb01458.x","article-title":"Attention disorder in a group of young Down\u2019s syndrome children","volume":"33","author":"Green","year":"1989","journal-title":"Journal of Intellectual Disability Research"},{"issue":"1","key":"10.1016\/j.ridd.2024.104788_bib36","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.ridd.2004.12.002","article-title":"Internet survey of treatments used by parents of children with autism","volume":"27","author":"Green","year":"2006","journal-title":"Research in Developmental Disabilities"},{"key":"10.1016\/j.ridd.2024.104788_bib37","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/978-1-60761-725-9_32","article-title":"Behavioral morbidity in pediatric sleep-disordered breathing","author":"Hodges","year":"2012","journal-title":"Sleeping Disordered Breathing in Children"},{"key":"10.1016\/j.ridd.2024.104788_bib38","unstructured":"Hoffmire, C.A. (2012). Examination of Sleep Disturbances in Children with Down Syndrome and Multiple Comorbidities in New York State (Doctoral dissertation, University of Rochester)."},{"issue":"4","key":"10.1016\/j.ridd.2024.104788_bib39","doi-asserted-by":"crossref","first-page":"411","DOI":"10.5664\/jcsm.3618","article-title":"High prevalence of sleep disorders and associated comorbidities in a community sample of children with down syndrome","volume":"10","author":"Hoffmire","year":"2014","journal-title":"Journal of Clinical Sleeping Medicine"},{"issue":"1","key":"10.1016\/j.ridd.2024.104788_bib40","first-page":"6","article-title":"Gastrointestinal disorders in Down syndrome","volume":"7","author":"Holmes","year":"2014","journal-title":"Gastroenterology and Hepatology from Bed to Bench"},{"issue":"195","key":"10.1016\/j.ridd.2024.104788_bib41","first-page":"195","article-title":"The usage and perceived outcomes of early intervention and early childhood programs for young children with Autism Spectrum Disorder","volume":"254","author":"Hume","year":"2005","journal-title":"TECSE National Research Council"},{"issue":"11","key":"10.1016\/j.ridd.2024.104788_bib42","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1080\/03004430.2016.1180790","article-title":"Sleep disturbances, behavioural problems and adaptive skills in children with Down\u2019s syndrome","volume":"187","author":"Kelmanson","year":"2017","journal-title":"Early Child Development and Care"},{"issue":"4","key":"10.1016\/j.ridd.2024.104788_bib43","first-page":"275","article-title":"Comprehensive communication intervention for infants and toddlers with down syndrome. Infant-toddler Intervention","volume":"1","author":"Kumin","year":"1991","journal-title":"The Transdisciplinary Journal"},{"issue":"3","key":"10.1016\/j.ridd.2024.104788_bib44","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1080\/17518423.2021.1922529","article-title":"Relationship between comorbid psychopathology in children and adolescents with autism spectrum disorder and parental well-being","volume":"25","author":"Lanyi","year":"2022","journal-title":"Developmental Neurorehabilitation"},{"issue":"7","key":"10.1016\/j.ridd.2024.104788_bib45","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.3390\/nu14071471","article-title":"Gastrointestinal symptoms in autism spectrum disorder: A systematic review","volume":"14","author":"Leader","year":"2022","journal-title":"Nutrients"},{"key":"10.1016\/j.ridd.2024.104788_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.rasd.2022.101915","article-title":"Affective problems, gastrointestinal symptoms, sleep problems and challenging behavior in children and adolescents with autism spectrum disorder","volume":"92","author":"Leader","year":"2022","journal-title":"Research in Autism Spectrum Disorders"},{"issue":"1","key":"10.1016\/j.ridd.2024.104788_bib47","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1111\/jir.12789","article-title":"Relationships among gastrointestinal symptoms, sleep problems, challenging behavior, comorbid psychopathology and autism spectrum disorder symptoms in children and adolescents with 15q Duplication Syndrome","volume":"65","author":"Leader","year":"2021","journal-title":"Journal of Intellectual Disability Research"},{"key":"10.1016\/j.ridd.2024.104788_bib48","series-title":"Comorbid Conditions Among Children with Autism Spectrum Disorders","first-page":"257","article-title":"Gastrointestinal Disorders","author":"Leader","year":"2016"},{"issue":"1","key":"10.1016\/j.ridd.2024.104788_bib49","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1080\/17518423.2020.1770353","article-title":"Complex Comorbid Presentations are Associated with Harmful Behaviour Problems among children and adolescents with Cerebral Palsy","volume":"24","author":"Leader","year":"2021","journal-title":"Developmental Neurorehabilitation"},{"key":"10.1016\/j.ridd.2024.104788_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.ridd.2020.103698","article-title":"Relationship between Parent-reported Gastrointestinal Symptoms, Sleep Problems, Autism Spectrum Disorder Symptoms, and Behavior Problems in Children and Adolescents with 22q11.2 Deletion Syndrome","volume":"104","author":"Leader","year":"2020","journal-title":"Research in Developmental Disabilities"},{"issue":"1","key":"10.1016\/j.ridd.2024.104788_bib51","doi-asserted-by":"crossref","DOI":"10.1080\/17518423.2020.1770354","article-title":"Comorbid feeding and gastrointestinal symptoms, challenging behavior, sensory issues, adaptive functioning and quality of life in children and adolescents with autism spectrum disorder","volume":"24","author":"Leader","year":"2021","journal-title":"Developmental Neurorehabilitation"},{"issue":"2","key":"10.1016\/j.ridd.2024.104788_bib52","doi-asserted-by":"crossref","first-page":"45","DOI":"10.3104\/reports.291","article-title":"Parental experiences of feeding problems in their infants with Down syndrome","volume":"9","author":"Lewis","year":"2004","journal-title":"Down syndrome Research and Practice"},{"issue":"3","key":"10.1016\/j.ridd.2024.104788_bib53","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1111\/jir.12321","article-title":"Sleep problems and temperament in young children with Down syndrome and typically developing controls","volume":"61","author":"Lukowski","year":"2017","journal-title":"Journal of Intellectual Disability Research"},{"key":"10.1016\/j.ridd.2024.104788_bib54","doi-asserted-by":"crossref","DOI":"10.1016\/j.ridd.2019.103512","article-title":"Sleep problems and recall memory in children with Down syndrome and typically developing controls","volume":"96","author":"Lukowski","year":"2020","journal-title":"Research in Developmental Disabilities"},{"issue":"4","key":"10.1016\/j.ridd.2024.104788_bib55","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1016\/j.ridd.2013.01.010","article-title":"Prevalence and risk markers of behavior problems among adults with intellectual disabilities: A total population study in \u00d6rebro County, Sweden","volume":"34","author":"Lundqvist","year":"2013","journal-title":"Research in Developmental Disabilities"},{"issue":"5","key":"10.1016\/j.ridd.2024.104788_bib56","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1177\/000992280104000502","article-title":"Frequency of celiac disease in individuals with Down syndrome in the United States","volume":"40","author":"Mackey","year":"2001","journal-title":"Clinical Pediatrics"},{"key":"10.1016\/j.ridd.2024.104788_bib57","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1002\/bdr2.1589","article-title":"National population-based estimates for major birth defects, 2010-2014","volume":"1111","author":"Mai","year":"2019","journal-title":"Birth Defects Research"},{"issue":"92","key":"10.1016\/j.ridd.2024.104788_bib58","article-title":"Distribution and age of onset of psychopathological risk in a cohort of children with Down syndrome in developmental age","volume":"45","author":"Marino","year":"2019","journal-title":"Italian Journal of Pediatrics"},{"key":"10.1016\/j.ridd.2024.104788_bib59","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.ijporl.2015.12.014","article-title":"Sleep problems and obstructive sleep apnea in children with down syndrome, an overview","volume":"82","author":"Maris","year":"2016","journal-title":"International Journal of Pediatric Otorhinolaryngology"},{"key":"10.1016\/j.ridd.2024.104788_bib60","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1111\/j.1365-2788.2012.01608.x","article-title":"Therapy treatment use among individuals with fragile X syndrome: Findings from a US parent survey","volume":"57","author":"Martin","year":"2013","journal-title":"Journal of Intellectual Disability Research"},{"key":"10.1016\/j.ridd.2024.104788_bib61","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/s10882-007-9086-0","article-title":"Stereotypy in adults with autism spectrum disorders: Relationship and diagnostic fidelity","volume":"20","author":"Matson","year":"2008","journal-title":"Journal of Developmental and Physical Disabilities"},{"key":"10.1016\/j.ridd.2024.104788_bib62","series-title":"Autism Spectrum Disorders","article-title":"Comorbidity \u2013 Child Version","author":"Matson","year":"2007"},{"issue":"3","key":"10.1016\/j.ridd.2024.104788_bib63","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1080\/19315864.2010.495920","article-title":"Effects of symptoms of comorbid psychopathology on challenging behaviors among atypically developing infants and toddlers as assessed with the baby and infant screen for children with autism traits (BISCUIT)","volume":"3","author":"Matson","year":"2010","journal-title":"Journal of Mental Health Research in Intellectual Disabilities"},{"issue":"4","key":"10.1016\/j.ridd.2024.104788_bib64","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.ridd.2005.12.004","article-title":"Comorbid psychopathology with autism spectrum disorder in children: An overview","volume":"28","author":"Matson","year":"2007","journal-title":"Research in Developmental Disabilities"},{"issue":"5","key":"10.1016\/j.ridd.2024.104788_bib65","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1177\/1362361313485164","article-title":"The association between emotional and behavioral problems and gastrointestinal symptoms among children with high-functioning autism","volume":"18","author":"Mazefsky","year":"2014","journal-title":"Autism"},{"key":"10.1016\/j.ridd.2024.104788_bib66","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.rasd.2012.11.004","article-title":"Physical aggression in children and adolescents with autism spectrum disorders","volume":"7","author":"Mazurek","year":"2013","journal-title":"Research in Autism Spectrum Disorders"},{"issue":"1","key":"10.1016\/j.ridd.2024.104788_bib67","first-page":"26","article-title":"Depressive disorders in adults with Down syndrome","volume":"15","author":"McGuire","year":"1996","journal-title":"The Habilitative Mental Healthcare Newsletter"},{"issue":"11","key":"10.1016\/j.ridd.2024.104788_bib68","doi-asserted-by":"crossref","first-page":"3639","DOI":"10.1016\/j.ridd.2013.08.002","article-title":"The progression of severe behavior disorder in young children with intellectual and developmental disabilities","volume":"34","author":"Medeiros","year":"2013","journal-title":"Research in Developmental Disabilities"},{"issue":"1","key":"10.1016\/j.ridd.2024.104788_bib69","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1136\/jms.9.1.2","article-title":"Revised estimates of the maternal age specific live birth prevalence of Down's syndrome","volume":"9","author":"Morris","year":"2002","journal-title":"Journal of Medical Screening"},{"issue":"2","key":"10.1016\/j.ridd.2024.104788_bib70","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1515\/JPEM.2008.21.2.155","article-title":"Thyroid dysfunction in Down\u2019s syndrome and screening for hypothyroidism in children and adolescents using capillary TSH measurement.","volume":"21","author":"Murphy","year":"2008","journal-title":"Journal of Pediatric Endocrinology and Metabolism: JPEM"},{"issue":"4","key":"10.1016\/j.ridd.2024.104788_bib71","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/0891-4222(95)00015-F","article-title":"Major depression in a small group of adults with Down syndrome","volume":"16","author":"Myers","year":"1995","journal-title":"Research in Developmental Disabilities"},{"issue":"2","key":"10.1016\/j.ridd.2024.104788_bib72","first-page":"37","article-title":"Exploratory, Pilot Study: Treatments accessed by caregivers of children with Down Syndrome - An internet survey","volume":"23","author":"Neil","year":"2018","journal-title":"Journal on Developmental Disabilities"},{"issue":"8","key":"10.1016\/j.ridd.2024.104788_bib73","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1093\/sleep\/23.8.1d","article-title":"The Children\u2019s Sleep Habits Questionnaire: Construction and validation of a sleep survey for school-aged children.","volume":"23","author":"Owens","year":"2000","journal-title":"Sleep"},{"key":"10.1016\/j.ridd.2024.104788_bib74","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1097\/00004703-200002000-00005","article-title":"Sleep habits and sleep disturbance in elementary school-aged children","volume":"21","author":"Owens","year":"2000","journal-title":"Journal of Developmental & Behavioral Pediatrics"},{"issue":"5","key":"10.1016\/j.ridd.2024.104788_bib75","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1053\/jpsu.2000.6049","article-title":"Combined pure esophageal atresia, duodenal atresia, biliary atresia, and pancreatic ductal atresia: prenatal diagnostic features and review of the literature","volume":"35","author":"Pameijer","year":"2000","journal-title":"Journal of Pediatric Surgery"},{"key":"10.1016\/j.ridd.2024.104788_bib76","unstructured":"Patterson, B. (2020). Managing Behavior. NDSS. https:\/\/www.ndss.org\/resources\/managing-behavior\/."},{"issue":"5","key":"10.1016\/j.ridd.2024.104788_bib77","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1111\/j.1365-2788.2011.01484.x","article-title":"Self-injurious behaviour in intellectual disability in syndrome: evidence for aberrant pain signalling as a contributing factor","volume":"56","author":"Peebles","year":"2012","journal-title":"Journal of Intellectual Disability Research"},{"issue":"1","key":"10.1016\/j.ridd.2024.104788_bib78","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1352\/0895-8017(2005)110<23:MOTDID>2.0.CO;2","article-title":"Misdiagnosis of thyroid disorders in Down syndrome: time to re-examine the myth?","volume":"110","author":"Prasher","year":"2005","journal-title":"American Journal of Mental Retardation"},{"issue":"1","key":"10.1016\/j.ridd.2024.104788_bib79","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1007\/s11920-015-0638-1","article-title":"Sleep disturbances in neurodevelopmental disorders","volume":"18","author":"Robinson-Shelton","year":"2016","journal-title":"Current Psychiatry Reports"},{"key":"10.1016\/j.ridd.2024.104788_bib80","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1023\/A:1013299028321","article-title":"The behavior problems inventory: an instrument for the assessment of self-injury, stereotyped behavior, and aggression\/destruction in individuals with developmental disabilities","volume":"31","author":"Rojahn","year":"2001","journal-title":"Journal of Autism and Developmental Disorders"},{"issue":"5","key":"10.1016\/j.ridd.2024.104788_bib81","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1111\/j.1365-2788.2011.01507.x","article-title":"The Behavior Problems Inventory\u2010Short Form for individuals with intellectual disabilities: Part I: development and provisional clinical reference data.","volume":"56","author":"Rojahn","year":"2012","journal-title":"Journal of Intellectual Disability Research"},{"issue":"5","key":"10.1016\/j.ridd.2024.104788_bib82","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1111\/j.1365-2788.2011.01506.x","article-title":"The Behavior Problems Inventory\u2010Short Form for individuals with intellectual disabilities: Part II: reliability and validity.","volume":"56","author":"Rojahn","year":"2012","journal-title":"Journal of Intellectual Disability Research"},{"issue":"2","key":"10.1016\/j.ridd.2024.104788_bib83","doi-asserted-by":"crossref","first-page":"108","DOI":"10.5455\/msm.2018.30.108-112","article-title":"Mastery motivation in children with cerebral palsy (CP) based on parental report: validity and reliability of dimensions of mastery questionnaire in Persian","volume":"30","author":"Salavati","year":"2018","journal-title":"Materia Socio-medica"},{"key":"10.1016\/j.ridd.2024.104788_bib84","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1177\/1362361316689330","article-title":"Self-injurious behaviors in children with autism spectrum disorder enrolled in the study to explore early development","volume":"22","author":"Soke","year":"2018","journal-title":"Autism"},{"key":"10.1016\/j.ridd.2024.104788_bib85","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1002\/(SICI)1096-8628(19990625)89:2<96::AID-AJMG7>3.0.CO;2-4","article-title":"Down syndrome: perinatal complications and counselling experiences in 216 patients","volume":"89","author":"Spaphis","year":"1999","journal-title":"American Journal of Medical Genetics"},{"key":"10.1016\/j.ridd.2024.104788_bib86","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.rasd.2011.07.016","article-title":"Cutoff scores for the Autism Spectrum Disorder\u2013 Comorbid for Children (ASD-CC)","volume":"6","author":"Thorson","year":"2012","journal-title":"Research in Autism Spectrum Disorders"},{"issue":"7","key":"10.1016\/j.ridd.2024.104788_bib87","doi-asserted-by":"crossref","first-page":"1766","DOI":"10.1016\/j.ridd.2014.02.013","article-title":"An examination of the relationship between autism spectrum disorder, intellectual functioning, and comorbid symptoms in children","volume":"3","author":"Tureck","year":"2014","journal-title":"Research in Developmental Disabilities"},{"issue":"5","key":"10.1016\/j.ridd.2024.104788_bib88","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1016\/j.jpeds.2013.06.054","article-title":"Problem behavior of individuals with Down syndrome in a nationwide cohort assessed in late adolescence","volume":"163","author":"van Gameren-Oosterom","year":"2013","journal-title":"The Journal of Pediatrics"},{"issue":"12","key":"10.1016\/j.ridd.2024.104788_bib89","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1007\/s00431-010-1253-0","article-title":"Clinical practice. The care of children with Down syndrome","volume":"169","author":"Weijerman","year":"2010","journal-title":"European Journal of Pediatrics"},{"key":"10.1016\/j.ridd.2024.104788_bib90","doi-asserted-by":"crossref","unstructured":"Williams, K.C., Christofi, F.L., Clemmons, T., Rosenberg, D. & Fuchs, G.J. (2012a). Association of chronic gastrointestinal symptoms with sleep problems may help identify distinct subgroups of autism spectrum disorders. Gastroenterology, 142 (5), (Suppl.1), S-714.","DOI":"10.1016\/S0016-5085(12)62767-X"},{"key":"10.1016\/j.ridd.2024.104788_bib91","doi-asserted-by":"crossref","unstructured":"Williams, K.C., Christofi, F.L., Clemmons, T., Rosenberg, D., & Fuchs, G.J. (2012b). Chronic GI symptoms in children with autism spectrum disorders are associated with clinical anxiety. Gastroenterology, 142 (5), (Suppl. 1), S-79-S-80.","DOI":"10.1016\/S0016-5085(12)60303-5"},{"key":"10.1016\/j.ridd.2024.104788_bib92","doi-asserted-by":"crossref","unstructured":"Williams, K.C., Fuchs, G.J., Furuta, G.T., Marcon, M.A., & Coury, D.L. (2010). Clinical features associated with GI symptoms in Autism Spectrum Disorders (ASD). Gastroenterology, 138 (5), (Suppl. 1), S-74.","DOI":"10.1016\/S0016-5085(10)60337-X"}],"container-title":["Research in Developmental Disabilities"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0891422224001203?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0891422224001203?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T10:40:37Z","timestamp":1721299237000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0891422224001203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":92,"alternative-id":["S0891422224001203"],"URL":"https:\/\/doi.org\/10.1016\/j.ridd.2024.104788","relation":{},"ISSN":["0891-4222"],"issn-type":[{"value":"0891-4222","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"An investigation of sleep problems, gastrointestinal symptoms, comorbid psychopathology and challenging behavior in children and adolescents with Down Syndrome","name":"articletitle","label":"Article Title"},{"value":"Research in Developmental Disabilities","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ridd.2024.104788","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"104788"}}