{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T16:10:38Z","timestamp":1740672638079,"version":"3.38.0"},"reference-count":11,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,25]],"date-time":"2025-01-25T00:00:00Z","timestamp":1737763200000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010800","name":"Hadassah Medical Center","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010800","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Medicine Case Reports"],"published-print":{"date-parts":[[2025]]},"DOI":"10.1016\/j.rmcr.2025.102171","type":"journal-article","created":{"date-parts":[[2025,1,25]],"date-time":"2025-01-25T23:19:04Z","timestamp":1737847144000},"page":"102171","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Non-classical pulmonary exacerbation in cystic fibrosis revealing ALK-Translocated lung cancer: A case report"],"prefix":"10.1016","volume":"53","author":[{"given":"Mohamad","family":"Hadhud","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johnathan","family":"Arnon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anat","family":"Hershko-Moshe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adi","family":"Hollander","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noa","family":"Hurvitz-Lehmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Assaf","family":"Potruch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henny","family":"Azmanov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rottem","family":"Kuint","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nurith","family":"Hiller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elie","family":"Picard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naama","family":"Sebbag-Sznajder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shira","family":"Leebhoff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Wilschanski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myriam","family":"Grunewald","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liron","family":"Birimberg-Schwartz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7119-5675","authenticated-orcid":false,"given":"Malena","family":"Cohen-Cymberknoh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.rmcr.2025.102171_bib1","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.jcf.2021.07.004","article-title":"Incidence and risk factors of cancer in individuals with cystic fibrosis in the UK; a case-control study","volume":"21","author":"Archangelidi","year":"2022","journal-title":"J. Cyst. Fibros."},{"key":"10.1016\/j.rmcr.2025.102171_bib2","article-title":"Treatment effects of CFTR modulators on people with Cystic Fibrosis carrying the Q359K\/T360K variant","author":"Yaacoby-Bianu","year":"2024","journal-title":"ERJ Open Res"},{"key":"10.1016\/j.rmcr.2025.102171_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.xpro.2020.100019","article-title":"Protocol for application, standardization and validation of the forskolin-induced swelling assay in cystic fibrosis human colon organoids","volume":"1","author":"Vonk","year":"2020","journal-title":"STAR Protoc"},{"key":"10.1016\/j.rmcr.2025.102171_bib4","doi-asserted-by":"crossref","first-page":"2107","DOI":"10.3892\/ijo.2015.2921","article-title":"The cystic fibrosis transmembrane conductance regulator as a biomarker in non-small cell lung cancer","volume":"46","author":"Li","year":"2015","journal-title":"Int. J. Oncol."},{"key":"10.1016\/j.rmcr.2025.102171_bib5","doi-asserted-by":"crossref","DOI":"10.1200\/JCO.24.00581","article-title":"Lorlatinib versus crizotinib in patients with advanced ALK-positive non-small cell lung cancer: 5-year outcomes from the phase III CROWN study","author":"Solomon","year":"2024","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.rmcr.2025.102171_bib6","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.jcf.2016.11.006","article-title":"Pleural effusions in non-transplanted cystic fibrosis patients","volume":"16","author":"Belanger","year":"2017","journal-title":"J. Cyst. Fibros."},{"key":"10.1016\/j.rmcr.2025.102171_bib7","doi-asserted-by":"crossref","first-page":"S60","DOI":"10.1016\/j.jcf.2019.11.002","article-title":"Intestinal organoids for cystic fibrosis research","volume":"19","author":"de Poel","year":"2020","journal-title":"J. Cyst. Fibros."},{"key":"10.1016\/j.rmcr.2025.102171_bib8","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1002\/1878-0261.13446","article-title":"EML4-ALK biology and drug resistance in non-small cell lung cancer: a new phase of discoveries","volume":"17","author":"Elshatlawy","year":"2023","journal-title":"Mol. Oncol."},{"key":"10.1016\/j.rmcr.2025.102171_bib9","doi-asserted-by":"crossref","DOI":"10.1038\/s41401-024-01427-0","article-title":"Ivacaftor, a CFTR potentiator, synergizes with osimertinib against acquired resistance to osimertinib in NSCLC by regulating CFTR-PTEN-AKT axis","author":"Li","year":"2024","journal-title":"Acta Pharmacol. Sin."},{"issue":"4","key":"10.1016\/j.rmcr.2025.102171_bib10","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1139\/bcb-2020-0522","article-title":"Epidermal growth factor receptor activity upregulates lactate dehydrogenase A expression, lactate dehydrogenase activity, and lactate secretion in cultured IB3-1 cystic fibrosis lung epithelial cells","volume":"99","author":"Massip-Copiz","year":"2021","journal-title":"Biochem. Cell. Biol."},{"key":"10.1016\/j.rmcr.2025.102171_bib11","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1016\/j.celrep.2019.01.068","article-title":"Rectal organoids enable personalized treatment of cystic fibrosis","volume":"26","author":"Berkers","year":"2019","journal-title":"Cell Rep."}],"container-title":["Respiratory Medicine Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213007125000073?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213007125000073?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T15:28:54Z","timestamp":1740670134000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213007125000073"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":11,"alternative-id":["S2213007125000073"],"URL":"https:\/\/doi.org\/10.1016\/j.rmcr.2025.102171","relation":{},"ISSN":["2213-0071"],"issn-type":[{"type":"print","value":"2213-0071"}],"subject":[],"published":{"date-parts":[[2025]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Non-classical pulmonary exacerbation in cystic fibrosis revealing ALK-Translocated lung cancer: A case report","name":"articletitle","label":"Article Title"},{"value":"Respiratory Medicine Case Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rmcr.2025.102171","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"102171"}}