{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T00:59:38Z","timestamp":1774400378151,"version":"3.50.1"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T00:00:00Z","timestamp":1771372800000},"content-version":"vor","delay-in-days":48,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Medicine Case Reports"],"published-print":{"date-parts":[[2026]]},"DOI":"10.1016\/j.rmcr.2026.102389","type":"journal-article","created":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T00:25:24Z","timestamp":1771460724000},"page":"102389","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Case report: Primary pulmonary rhabdomyosarcoma exhibiting epithelial morphology and unusual immunophenotype \u2013 A significant diagnostic pitfall"],"prefix":"10.1016","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-7810-6608","authenticated-orcid":false,"given":"Zonghua","family":"Wen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenting","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongyun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuxu","family":"Wen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yungang","family":"Lv","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruodai","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuhong","family":"Meng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.rmcr.2026.102389_bib1","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1111\/his.14265","article-title":"Updates from the 2020 world health organization classification of soft tissue and bone tumours","volume":"78","author":"Anderson","year":"2021","journal-title":"Histopathology"},{"issue":"3","key":"10.1016\/j.rmcr.2026.102389_bib2","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1111\/j.1699-0463.1989.tb00783.x","article-title":"Rhabdomyosarcoma in middle-aged and elderly individuals","volume":"97","author":"Seidal","year":"1989","journal-title":"APMIS"},{"key":"10.1016\/j.rmcr.2026.102389_bib3","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1186\/s13000-015-0349-2","article-title":"Epithelioid rhabdomyosarcoma; a case report with immunohistochemical and molecular study","volume":"10","author":"Jokoji","year":"2015","journal-title":"Diagn. Pathol."},{"issue":"5","key":"10.1016\/j.rmcr.2026.102389_bib4","doi-asserted-by":"crossref","first-page":"e308","DOI":"10.1016\/j.oooo.2020.01.004","article-title":"Epithelioid rhabdomyosarcoma: report of the first case in the jaw","volume":"130","author":"de Aguiar","year":"2020","journal-title":"Oral Surg. Oral Med. Oral Pathol. Oral Radiol."},{"issue":"1","key":"10.1016\/j.rmcr.2026.102389_bib5","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1186\/s13000-019-0917-y","article-title":"Primary epithelioid rhabdomyosarcoma of the stomach: a case report and review of literature","volume":"14","author":"Wang","year":"2019","journal-title":"Diagn. Pathol."},{"issue":"11","key":"10.1016\/j.rmcr.2026.102389_bib6","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1002\/gcc.23185","article-title":"Comprehensive molecular profile of primary cutaneous epithelioid rhabdomyosarcoma: a tumor genomically and molecularly related to malignant melanoma","volume":"62","author":"Shafi","year":"2023","journal-title":"Genes Chromosomes Cancer"},{"issue":"7","key":"10.1016\/j.rmcr.2026.102389_bib7","doi-asserted-by":"crossref","first-page":"951","DOI":"10.3390\/medicina58070951","article-title":"Epithelioid rhabdomyosarcoma at the high parietal area of the head: a case report","volume":"58","author":"Jung","year":"2022","journal-title":"Medicina (Kaunas)"},{"issue":"3","key":"10.1016\/j.rmcr.2026.102389_bib8","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1177\/10668969211049832","article-title":"Primary epithelioid rhabdomyosarcoma of the liver: case report of an unusual histological variant","volume":"30","author":"Nakamura","year":"2022","journal-title":"Int. J. Surg. Pathol."},{"issue":"7","key":"10.1016\/j.rmcr.2026.102389_bib9","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1097\/PAT.0000000000000321","article-title":"Epithelioid rhabdomyosarcoma: a clinicopathological study of seven additional cases supporting a distinctive variant with aggressive biological behaviour","volume":"47","author":"Yu","year":"2015","journal-title":"Pathology"},{"issue":"4","key":"10.1016\/j.rmcr.2026.102389_bib10","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1007\/s00428-024-03838-0","article-title":"\u201cAberrant\u201d expression of skeletal muscle markers in neuroendocrine carcinomas: a significant diagnostic pitfall","volume":"485","author":"Garcia-Porrero","year":"2024","journal-title":"Virchows Arch."},{"issue":"10","key":"10.1016\/j.rmcr.2026.102389_bib11","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1111\/j.1440-1827.2009.02438.x","article-title":"Small cell carcinoma with skeletal muscle differentiation of urinary bladder","volume":"59","author":"Yajima","year":"2009","journal-title":"Pathol. Int."},{"issue":"10","key":"10.1016\/j.rmcr.2026.102389_bib12","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1034\/j.1600-0560.2002.291010.x","article-title":"Merkel cell (primary neuroendocrine) carcinoma of the skin with nodal metastasis showing rhabdomyosarcomatous differentiation","volume":"29","author":"Fern\u00e1ndez-Figueras","year":"2002","journal-title":"J. Cutan. Pathol."},{"issue":"2","key":"10.1016\/j.rmcr.2026.102389_bib13","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1097\/00000478-200002000-00008","article-title":"Small cell neuroendocrine carcinoma with skeletal muscle differentiation: report of three cases","volume":"24","author":"Eusebi","year":"2000","journal-title":"Am. J. Surg. Pathol."},{"issue":"9","key":"10.1016\/j.rmcr.2026.102389_bib14","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1097\/PAS.0b013e31822457e4","article-title":"TTF-1 in embryonal tumors: an immunohistochemical study of 117 cases","volume":"35","author":"Galliani","year":"2011","journal-title":"Am. J. Surg. Pathol."},{"issue":"7","key":"10.1016\/j.rmcr.2026.102389_bib15","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1038\/modpathol.2008.86","article-title":"Aberrant expression of epithelial and neuroendocrine markers in alveolar rhabdomyosarcoma: a potentially serious diagnostic pitfall","volume":"21","author":"Bahrami","year":"2008","journal-title":"Mod. Pathol."},{"key":"10.1016\/j.rmcr.2026.102389_bib16","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.humpath.2019.03.007","article-title":"A comparison of adult rhabdomyosarcoma and high-grade neuroendocrine carcinoma of the urinary bladder reveals novel PPP1R12A fusions in rhabdomyosarcoma","volume":"88","author":"Gupta","year":"2019","journal-title":"Hum. Pathol."},{"issue":"7","key":"10.1016\/j.rmcr.2026.102389_bib17","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1097\/PAS.0b013e3181650e4a","article-title":"Rhabdomyosarcoma of the urinary bladder in adults: predilection for alveolar morphology with anaplasia and significant morphologic overlap with small cell carcinoma","volume":"32","author":"Paner","year":"2008","journal-title":"Am. J. Surg. Pathol."},{"issue":"5","key":"10.1016\/j.rmcr.2026.102389_bib18","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1007\/s00428-024-03926-1","article-title":"TTF-1 is a highly sensitive but not fully specific marker for pulmonary and thyroidal cancer: a tissue microarray study evaluating more than 17,000 tumors from 152 different tumor entities","volume":"485","author":"M\u00f6ller","year":"2024","journal-title":"Virchows Arch."},{"issue":"1","key":"10.1016\/j.rmcr.2026.102389_bib19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13000-025-01732-0","article-title":"Aberrant TTF-1 expression in metastatic colorectal adenocarcinoma mimicking primary lung cancer: a case report and review of diagnostic pitfalls","volume":"21","author":"Tran","year":"2025","journal-title":"Diagn. Pathol."},{"issue":"3","key":"10.1016\/j.rmcr.2026.102389_bib20","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1177\/10668969241286082","article-title":"Aberrant expression of pneumocytic markers (TTF-1 and Napsin-A) in biliary duct and gallbladder adenocarcinomas; A potential diagnostic pitfall","volume":"33","author":"Khedkar","year":"2025","journal-title":"Int. J. Surg. Pathol."},{"issue":"1","key":"10.1016\/j.rmcr.2026.102389_bib21","doi-asserted-by":"crossref","first-page":"e6","DOI":"10.1097\/PAI.0000000000000539","article-title":"TTF-1-positive metastatic endometrioid carcinoma: a case report and review of literature of a potential diagnostic pitfall","volume":"28","author":"Casteillo","year":"2020","journal-title":"Appl. Immunohistochem. Mol. Morphol."},{"issue":"5 & 6","key":"10.1016\/j.rmcr.2026.102389_bib22","doi-asserted-by":"crossref","first-page":"138","DOI":"10.5414\/NP301642","article-title":"TTF-1 immunohistochemistry in primary CNS tumors: a systematic review","volume":"43","author":"Das","year":"2024","journal-title":"Clin. Neuropathol."},{"issue":"2","key":"10.1016\/j.rmcr.2026.102389_bib23","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1177\/1066896920946835","article-title":"Aberrant TTF-1 expression in peripheral T-Cell lymphomas: a diagnostic pitfall","volume":"29","author":"Chang","year":"2021","journal-title":"Int. J. Surg. Pathol."},{"issue":"2","key":"10.1016\/j.rmcr.2026.102389_bib24","doi-asserted-by":"crossref","first-page":"E75","DOI":"10.1002\/dc.24588","article-title":"Aberrant expression of TTF1, p63, and cytokeratins in a diffuse large B-cell lymphoma","volume":"49","author":"Chornenkyy","year":"2021","journal-title":"Diagn. Cytopathol."},{"issue":"6","key":"10.1016\/j.rmcr.2026.102389_bib25","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1111\/j.1365-2559.2009.03298.x","article-title":"Value of immunohistochemistry in the differential diagnosis of pleural sarcomatoid mesothelioma from lung sarcomatoid carcinoma","volume":"54","author":"Takeshima","year":"2009","journal-title":"Histopathology"},{"issue":"3","key":"10.1016\/j.rmcr.2026.102389_bib26","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1097\/PAS.0b013e318185d21b","article-title":"TTF-1 expression in nephroblastoma","volume":"33","author":"Bisceglia","year":"2009","journal-title":"Am. J. Surg. Pathol."},{"issue":"5","key":"10.1016\/j.rmcr.2026.102389_bib27","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1111\/his.13789","article-title":"Immunohistochemistry for small-cell carcinoma: a potential diagnostic pitfall","volume":"74","author":"Wallace","year":"2019","journal-title":"Histopathology"}],"container-title":["Respiratory Medicine Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213007126000262?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213007126000262?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T00:20:17Z","timestamp":1774398017000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213007126000262"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":27,"alternative-id":["S2213007126000262"],"URL":"https:\/\/doi.org\/10.1016\/j.rmcr.2026.102389","relation":{},"ISSN":["2213-0071"],"issn-type":[{"value":"2213-0071","type":"print"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Case report: Primary pulmonary rhabdomyosarcoma exhibiting epithelial morphology and unusual immunophenotype \u2013 A significant diagnostic pitfall","name":"articletitle","label":"Article Title"},{"value":"Respiratory Medicine Case Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rmcr.2026.102389","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"102389"}}