{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T13:35:56Z","timestamp":1779197756948,"version":"3.51.4"},"reference-count":33,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,3,1]],"date-time":"2014-03-01T00:00:00Z","timestamp":1393632000000},"content-version":"vor","delay-in-days":730,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","resmedjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Medicine"],"published-print":{"date-parts":[[2012,3]]},"DOI":"10.1016\/j.rmed.2011.12.006","type":"journal-article","created":{"date-parts":[[2011,12,31]],"date-time":"2011-12-31T15:49:46Z","timestamp":1325346586000},"page":"329-337","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":34,"title":["Characterisation of asthma that develops during adolescence; findings from the Isle of Wight Birth Cohort"],"prefix":"10.1016","volume":"106","author":[{"given":"Ramesh J.","family":"Kurukulaaratchy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abid","family":"Raza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martha","family":"Scott","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula","family":"Williams","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Ewart","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharon","family":"Matthews","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graham","family":"Roberts","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Hasan Arshad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"15","key":"10.1016\/j.rmed.2011.12.006_bib1","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1056\/NEJMoa022363","article-title":"A longitudinal, population-based, cohort study of childhood asthma followed to adulthood","volume":"349","author":"Sears","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.rmed.2011.12.006_bib2","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1067\/mai.2002.120951","article-title":"The Melbourne asthma study: 1964\u20131999","volume":"109","author":"Phelan","year":"2002","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.rmed.2011.12.006_bib3","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1164\/rccm.200504-525OC","article-title":"Outcomes of asthma and wheezing in the first 6 years of life. Follow-up through adolescence","volume":"172","author":"Morgan","year":"2005","journal-title":"Am J Respir Crit Care Med"},{"issue":"3","key":"10.1016\/j.rmed.2011.12.006_bib4","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1164\/rccm.200711-1754OC","article-title":"Cluster analysis and clinical asthma phenotypes","volume":"178","author":"Haldar","year":"2008","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.rmed.2011.12.006_bib5","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1016\/S0140-6736(08)61447-6","article-title":"Wheezing and bronchial hyper-responsiveness in early childhood as predictors of newly diagnosed asthma in early adulthood: a longitudinal birth-cohort study","volume":"372","author":"Stern","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.rmed.2011.12.006_bib6","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1164\/rccm.200412-1738OC","article-title":"Sex differences in factors associated with childhood- and adolescent-onset wheeze","volume":"172","author":"Mandhane","year":"2005","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.rmed.2011.12.006_bib7","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/j.rmed.2006.09.022","article-title":"Female gender is associated with higher incidence and more stable respiratory symptoms during adolescence","volume":"101","author":"Tollefsen","year":"2007","journal-title":"Respiratory Med"},{"key":"10.1016\/j.rmed.2011.12.006_bib8","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1034\/j.1399-3038.2003.00047.x","article-title":"Longitudinal follow-up of the changing gender ratio in asthma from childhood to adulthood: role of delayed manifestation in girls","volume":"14","author":"Nicolai","year":"2003","journal-title":"Pediatr Allergy Immunol"},{"key":"10.1016\/j.rmed.2011.12.006_bib9","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1016\/j.jaci.2010.09.008","article-title":"Allergic rhinitis as a predictor for wheezing onset in school-aged children","volume":"126","author":"Rochat","year":"2010","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.rmed.2011.12.006_bib10","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/j.jaci.2007.07.020","article-title":"Childhood allergic rhinitis predicts asthma incidence and persistence to middle age: a longitudinal study","volume":"120","author":"Burgess","year":"2007","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.rmed.2011.12.006_bib11","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/S0140-6736(08)61446-4","article-title":"Rhinitis and onset of asthma: a longitudinal population-based study","volume":"372","author":"Shaaban","year":"2008","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.rmed.2011.12.006_bib12","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1067\/mai.2003.1623","article-title":"Factors influencing symptom expression in children with bronchial hyper-responsiveness at 10-years","volume":"112","author":"Kurukulaaratchy","year":"2003","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.rmed.2011.12.006_bib13","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1034\/j.1399-3003.1999.14a12.x","article-title":"Asymptomatic airway hyperresponsiveness: relationships with airway inflammation and remodelling","volume":"14","author":"Laprise","year":"1999","journal-title":"Eur Respir J"},{"key":"10.1016\/j.rmed.2011.12.006_bib14","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1136\/thx.2005.052241","article-title":"Bronchial hyperresponsiveness and the development of asthma and COPD in asymptomatic individuals: SAPALDIA cohort study","volume":"61","author":"Brutsche","year":"2006","journal-title":"Thorax"},{"key":"10.1016\/j.rmed.2011.12.006_bib15","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1136\/thx.2005.051227","article-title":"Smoking and the incidence of asthma during adolescence: results of a large cohort study in Germany","volume":"61","author":"Genuneit","year":"2006","journal-title":"Thorax"},{"key":"10.1016\/j.rmed.2011.12.006_bib16","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1136\/thx.2008.112136","article-title":"Early life origins of chronic obstructive pulmonary disease","volume":"65","author":"Svanes","year":"2010","journal-title":"Thorax"},{"issue":"2","key":"10.1016\/j.rmed.2011.12.006_bib17","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1164\/rccm.201005-0757OC","article-title":"Acetaminophen use and risk of asthma, rhinoconjunctivitis and eczema in adolescents: International Study of Asthma and Allergies in Childhood: phase","volume":"183","author":"Beasley","year":"2011","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"10.1016\/j.rmed.2011.12.006_bib18","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/0091-6749(92)90077-F","article-title":"Effect of environmental factors on the development of allergic disorders in infancy","volume":"90","author":"Arshad","year":"1992","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.rmed.2011.12.006_bib19","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/S0091-6749(98)70164-2","article-title":"The prevalence of and risk factors for atopy in early childhood: a whole population birth cohort study","volume":"101","author":"Tariq","year":"1998","journal-title":"J Allergy Clin Immunol"},{"issue":"3","key":"10.1016\/j.rmed.2011.12.006_bib20","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1053\/rmed.2001.1236","article-title":"The prevalence of asthma and wheezing illnesses amongst 10-year-old schoolchildren","volume":"96","author":"Kurukulaaratchy","year":"2002","journal-title":"Respir Med"},{"issue":"3","key":"10.1016\/j.rmed.2011.12.006_bib21","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1183\/09031936.95.08030483","article-title":"International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods","volume":"8","author":"Asher","year":"1995","journal-title":"Eur Respir J"},{"issue":"3","key":"10.1016\/j.rmed.2011.12.006_bib22","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0168-8510(90)90421-9","article-title":"EuroQol\u2013a new facility for the measurement of health-related quality of life","volume":"16","year":"1990","journal-title":"Health Policy"},{"key":"10.1016\/j.rmed.2011.12.006_bib23","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1136\/thx.2009.125443","article-title":"Influence of atopy and asthma on exhaled nitric oxide in an unselected birth cohort","volume":"65","author":"Scott","year":"2010","journal-title":"Thorax"},{"key":"10.1016\/j.rmed.2011.12.006_bib24","first-page":"3s","article-title":"Sputum induction","volume":"37","author":"Paggiaro","year":"2002","journal-title":"Eur Respir J Suppl"},{"key":"10.1016\/j.rmed.2011.12.006_bib25","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.jaci.2010.06.018","article-title":"Gender differences in asthma development and remission during transition through puberty: The TRacking Adolescents' Individual Lives Survey (TRAILS) study","volume":"126","author":"Vink","year":"2010","journal-title":"J Allergy Clin Immunol"},{"issue":"6","key":"10.1016\/j.rmed.2011.12.006_bib26","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1111\/j.1365-2222.2011.03765.x","article-title":"The influence of gender and atopy on the natural history of rhinitis in the first 18 years of life","volume":"41","author":"Kurukulaaratchy","year":"2011","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.rmed.2011.12.006_bib27","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1164\/rccm.200703-427OC","article-title":"Allergic rhinitis and onset of bronchial hyperresponsiveness. A population based study","volume":"176","author":"Shaaban","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"issue":"9357","key":"10.1016\/j.rmed.2011.12.006_bib28","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/S0140-6736(06)69263-5","article-title":"The relationship between asthma and allergic rhinitis","volume":"368","author":"Demoly","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.rmed.2011.12.006_bib29","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1002\/ppul.10155","article-title":"Outcome in adulthood of asymptomatic airway hyperresponsiveness in childhood: a longitudinal population study","volume":"34","author":"Rasmussen","year":"2002","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.rmed.2011.12.006_bib30","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1183\/09031936.02.00208102","article-title":"Lung and thorax development during adolescence: relationship with pubertal status","volume":"20","author":"Neve","year":"2002","journal-title":"Eur Respir J"},{"key":"10.1016\/j.rmed.2011.12.006_bib31","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1378\/chest.09-0865","article-title":"Acetaminophen use and the risk of asthma in children and adults: a systematic review and metaanalysis","volume":"136","author":"Etminan","year":"2009","journal-title":"Chest"},{"key":"10.1016\/j.rmed.2011.12.006_bib32","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/S1081-1206(10)60879-4","article-title":"Asthma onset and relapse in adult life: the British 1958 birth cohort study","volume":"98","author":"Butland","year":"2007","journal-title":"Ann Allergy Asthma Immunol"},{"key":"10.1016\/j.rmed.2011.12.006_bib33","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/j.jaci.2007.01.045","article-title":"Allergic rhinitis and its impact on asthma update: allergen immunotherapy","volume":"119","author":"Passalacqua","year":"2007","journal-title":"J Allergy Clin Immunol"}],"container-title":["Respiratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611111004720?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611111004720?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T11:15:29Z","timestamp":1760613329000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0954611111004720"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3]]},"references-count":33,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,3]]}},"alternative-id":["S0954611111004720"],"URL":"https:\/\/doi.org\/10.1016\/j.rmed.2011.12.006","relation":{},"ISSN":["0954-6111"],"issn-type":[{"value":"0954-6111","type":"print"}],"subject":[],"published":{"date-parts":[[2012,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characterisation of asthma that develops during adolescence; findings from the Isle of Wight Birth Cohort","name":"articletitle","label":"Article Title"},{"value":"Respiratory Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rmed.2011.12.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}