{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T02:24:08Z","timestamp":1767147848367,"version":"build-2238731810"},"reference-count":29,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2012,12,1]],"date-time":"2012-12-01T00:00:00Z","timestamp":1354320000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,12,1]],"date-time":"2012-12-01T00:00:00Z","timestamp":1354320000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T00:00:00Z","timestamp":1417392000000},"content-version":"vor","delay-in-days":730,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","resmedjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Medicine"],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1016\/j.rmed.2012.08.022","type":"journal-article","created":{"date-parts":[[2012,9,29]],"date-time":"2012-09-29T03:32:09Z","timestamp":1348889529000},"page":"1706-1714","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Indacaterol therapy in patients with COPD not receiving other maintenance treatment"],"prefix":"10.1016","volume":"106","author":[{"given":"Marc","family":"Decramer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Rossi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Lawrence","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danny","family":"McBryan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.rmed.2012.08.022_bib1","unstructured":"Global strategy for diagnosis, management and prevention of chronic obstructive pulmonary disease. Updated December 2011. At: http:\/\/www.goldcopd.org\/ [accessed 17.01.12]."},{"key":"10.1016\/j.rmed.2012.08.022_bib2","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1056\/NEJMoa063070","article-title":"Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease","volume":"356","author":"Calverley","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1016\/j.rmed.2012.08.022_bib3","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1164\/rccm.200712-1869OC","article-title":"Effect of pharmacotherapy on rate of decline of lung function in chronic obstructive pulmonary disease: results from the TORCH study","volume":"178","author":"Celli","year":"2008","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.rmed.2012.08.022_bib4","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1164\/rccm.200906-0876OC","article-title":"Mortality in the 4-year trial of tiotropium (UPLIFT) in patients with chronic obstructive pulmonary disease","volume":"180","author":"Celli","year":"2009","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.rmed.2012.08.022_bib5","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1016\/S0140-6736(09)61298-8","article-title":"Effect of tiotropium on outcomes in patients with moderate chronic obstructive pulmonary disease (UPLIFT): a prespecified subgroup analysis of a randomised controlled trial","volume":"374","author":"Decramer","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.rmed.2012.08.022_bib6","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1183\/09031936.00127809","article-title":"Tiotropium as a first maintenance drug in COPD: secondary analysis of the UPLIFT trial","volume":"36","author":"Troosters","year":"2010","journal-title":"Eur Respir J"},{"key":"10.1016\/j.rmed.2012.08.022_bib7","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1136\/thx.2009.133355","article-title":"Treatment of COPD: the sooner the better?","volume":"65","author":"Decramer","year":"2010","journal-title":"Thorax"},{"key":"10.1016\/j.rmed.2012.08.022_bib8","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1016\/j.rmed.2010.07.016","article-title":"COPD in young patients: a pre-specified analysis of the four-year trial of tiotropium (UPLIFT)","volume":"104","author":"Morice","year":"2010","journal-title":"Respir Med"},{"key":"10.1016\/j.rmed.2012.08.022_bib9","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1056\/NEJMoa1105482","article-title":"Changes in forced expiratory volume in 1 second over time in COPD","volume":"365","author":"Vestbo","year":"2011","journal-title":"N Engl J Med"},{"key":"10.1016\/j.rmed.2012.08.022_bib10","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1164\/rccm.201105-0831OC","article-title":"The progression of chronic obstructive pulmonary disease is heterogeneous: the experience of the BODE cohort","volume":"184","author":"Casanova","year":"2011","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.rmed.2012.08.022_bib11","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1183\/09031936.00045810","article-title":"Once-daily indacaterol versus twice-daily salmeterol for COPD: a placebo-controlled comparison","volume":"37","author":"Kornmann","year":"2011","journal-title":"Eur Respir J"},{"key":"10.1016\/j.rmed.2012.08.022_bib12","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1136\/thx.2009.125435","article-title":"Efficacy of a new once-daily long-acting inhaled \u03b22-agonist indacaterol versus twice-daily formoterol in COPD","volume":"65","author":"Dahl","year":"2010","journal-title":"Thorax"},{"key":"10.1016\/j.rmed.2012.08.022_bib13","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1164\/rccm.200910-1500OC","article-title":"Once-daily bronchodilators for chronic obstructive pulmonary disease: indacaterol versus tiotropium","volume":"182","author":"Donohue","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.rmed.2012.08.022_bib14","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1183\/09031936.00099306","article-title":"Outcomes for COPD pharmacological trials: from lung function to biomarkers","volume":"31","author":"Cazzola","year":"2008","journal-title":"Eur Respir J"},{"key":"10.1016\/j.rmed.2012.08.022_bib15","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1081\/COPD-200050666","article-title":"The MCID of the transition dyspnea index is a total score of one unit","volume":"2","author":"Mahler","year":"2005","journal-title":"COPD"},{"key":"10.1016\/j.rmed.2012.08.022_bib16","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/S0895-4356(02)00589-9","article-title":"Meaningful effect size and patterns of response of the transition dyspnea index","volume":"56","author":"Witek","year":"2003","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.rmed.2012.08.022_bib17","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1183\/09031936.03.00068503a","article-title":"Minimal important difference of the transition dyspnoea index in a multinational clinical trial","volume":"21","author":"Witek","year":"2003","journal-title":"Eur Respir J"},{"key":"10.1016\/j.rmed.2012.08.022_bib18","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1081\/COPD-200050513","article-title":"St. George's respiratory Questionnaire: MCID","volume":"2","author":"Jones","year":"2005","journal-title":"COPD"},{"issue":"Suppl. 5","key":"10.1016\/j.rmed.2012.08.022_bib19","doi-asserted-by":"crossref","first-page":"187S","DOI":"10.1378\/chest.107.5_Supplement.187S","article-title":"Issues concerning health-related quality of life in COPD","volume":"107","author":"Jones","year":"1995","journal-title":"Chest"},{"key":"10.1016\/j.rmed.2012.08.022_bib20","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1183\/09031936.02.00213202","article-title":"Interpretation of quality of life scores from the St George's respiratory Questionnaire","volume":"19","author":"Ferrer","year":"2002","journal-title":"Eur Respir J"},{"issue":"Suppl. 55","key":"10.1016\/j.rmed.2012.08.022_bib21","first-page":"P860","article-title":"Efficacy of indacaterol is maintained in patients with moderate or less and severe or worse COPD","volume":"38","author":"Korn","year":"2011","journal-title":"Eur Respir J"},{"key":"10.1016\/j.rmed.2012.08.022_bib22","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1016\/j.rmed.2011.02.013","article-title":"Profiling the effects of indacaterol on dyspnoea and health status in patients with COPD","volume":"105","author":"Jones","year":"2011","journal-title":"Respir Med"},{"key":"10.1016\/j.rmed.2012.08.022_bib23","doi-asserted-by":"crossref","first-page":"380","DOI":"10.4104\/pcrj.2011.00066","article-title":"Efficacy of indacaterol in the treatment of patients with COPD","volume":"20","author":"Jones","year":"2011","journal-title":"Prim Care Respir J"},{"key":"10.1016\/j.rmed.2012.08.022_bib24","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1164\/ajrccm.155.4.9105068","article-title":"Quality of life changes in COPD patients treated with salmeterol","volume":"155","author":"Jones","year":"1997","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.rmed.2012.08.022_bib25","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1183\/09031936.97.10040815","article-title":"An evaluation of salmeterol in the treatment of chronic obstructive pulmonary disease (COPD)","volume":"10","author":"Boyd","year":"1997","journal-title":"Eur Respir J"},{"issue":"6077","key":"10.1016\/j.rmed.2012.08.022_bib26","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1136\/bmj.1.6077.1645","article-title":"The natural history of chronic airflow obstruction","volume":"1","author":"Fletcher","year":"1977","journal-title":"Br Med J"},{"key":"10.1016\/j.rmed.2012.08.022_bib27","doi-asserted-by":"crossref","first-page":"169","DOI":"10.3132\/pcrj.2008.00037","article-title":"Bronchodilator efficacy of tiotropium in patients with mild to moderate COPD","volume":"17","author":"Johansson","year":"2008","journal-title":"Prim Care Respir J"},{"key":"10.1016\/j.rmed.2012.08.022_bib28","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/1465-9921-10-59","article-title":"Efficacy of salmeterol\/fluticasone propionate by GOLD stage of chronic obstructive pulmonary disease: analysis from the randomised, placebo-controlled TORCH study","volume":"10","author":"Jenkins","year":"2009","journal-title":"Respir Res"},{"key":"10.1016\/j.rmed.2012.08.022_bib29","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1183\/09031936.00191810","article-title":"Blinded 12-week comparison of once-daily indacaterol and tiotropium in COPD","volume":"38","author":"Buhl","year":"2011","journal-title":"Eur Respir J"}],"updated-by":[{"DOI":"10.1016\/j.rmed.2012.10.015","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000}}],"container-title":["Respiratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611112003186?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611112003186?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T11:19:55Z","timestamp":1760613595000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0954611112003186"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12]]},"references-count":29,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["S0954611112003186"],"URL":"https:\/\/doi.org\/10.1016\/j.rmed.2012.08.022","relation":{},"ISSN":["0954-6111"],"issn-type":[{"value":"0954-6111","type":"print"}],"subject":[],"published":{"date-parts":[[2012,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Indacaterol therapy in patients with COPD not receiving other maintenance treatment","name":"articletitle","label":"Article Title"},{"value":"Respiratory Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rmed.2012.08.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}