{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T11:41:56Z","timestamp":1760614916390,"version":"build-2065373602"},"reference-count":23,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2012,12,1]],"date-time":"2012-12-01T00:00:00Z","timestamp":1354320000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,12,1]],"date-time":"2012-12-01T00:00:00Z","timestamp":1354320000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T00:00:00Z","timestamp":1417392000000},"content-version":"vor","delay-in-days":730,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","resmedjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Medicine"],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1016\/j.rmed.2012.09.002","type":"journal-article","created":{"date-parts":[[2012,10,4]],"date-time":"2012-10-04T20:46:06Z","timestamp":1349383566000},"page":"1715-1721","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Assessing efficacy of indacaterol in moderate and severe COPD patients: A 12-week study in an Asian population"],"prefix":"10.1016","volume":"106","author":[{"given":"Yasuo","family":"To","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaharu","family":"Kinoshita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang Haak","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang-Wen","family":"Hang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masakazu","family":"Ichinose","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshinosuke","family":"Fukuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuji","family":"Kitawaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoko","family":"Okino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niyati","family":"Prasad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Lawrence","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Kramer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.rmed.2012.09.002_bib1","unstructured":"Global Initiative for Chronic Obstructive Lung Disease (GOLD). Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. Revised 2011. At: www.goldcopd.org [accessed 28.01.12]."},{"key":"10.1016\/j.rmed.2012.09.002_bib2","first-page":"CD001104","article-title":"Long-acting beta2-agonists for poorly reversible chronic obstructive pulmonary disease","volume":"3","author":"Appleton","year":"2006","journal-title":"Cochrane Database Syst Rev"},{"year":"2008","series-title":"Asthma and COPD: basic mechanisms and clinical management","author":"Barnes","key":"10.1016\/j.rmed.2012.09.002_bib3"},{"key":"10.1016\/j.rmed.2012.09.002_bib4","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1517\/13543784.14.7.775","article-title":"Ultra long-acting \u03b22-agonists in development for asthma and chronic obstructive pulmonary disease","volume":"14","author":"Cazzola","year":"2005","journal-title":"Expert Opin Investig Drugs"},{"key":"10.1016\/j.rmed.2012.09.002_bib5","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1136\/thx.2009.125435","article-title":"Efficacy of a new once-daily long-acting inhaled \u03b22-agonist indacaterol versus twice-daily formoterol in COPD","volume":"65","author":"Dahl","year":"2010","journal-title":"Thorax"},{"key":"10.1016\/j.rmed.2012.09.002_bib6","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1164\/rccm.200910-1500OC","article-title":"Once-daily bronchodilators for chronic obstructive pulmonary disease: indacaterol versus tiotropium","volume":"182","author":"Donohue","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.rmed.2012.09.002_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2466-10-11","article-title":"Efficacy and safety of indacaterol 150\u00a0\u03bcg once-daily in COPD: a double-blind, randomised, 12-week study","volume":"10","author":"Feldman","year":"2010","journal-title":"BMC Pulm Med"},{"key":"10.1016\/j.rmed.2012.09.002_bib8","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1183\/09031936.00045810","article-title":"Once-daily indacaterol vs twice-daily salmeterol for COPD: a placebo-controlled comparison","volume":"37","author":"Kornmann","year":"2011","journal-title":"Eur Respir J"},{"key":"10.1016\/j.rmed.2012.09.002_bib9","doi-asserted-by":"crossref","first-page":"247","DOI":"10.2165\/11586520-000000000-00000","article-title":"Efficacy and pharmacokinetics of indacaterol in Caucasian and Japanese patients with chronic obstructive pulmonary disease: a comparison of two randomized placebo-controlled studies","volume":"31","author":"Hosoe","year":"2011","journal-title":"Clin Drug Invest"},{"key":"10.1016\/j.rmed.2012.09.002_bib10","doi-asserted-by":"crossref","first-page":"285","DOI":"10.2332\/allergolint.10-OA-0173","article-title":"Bronchodilator efficacy of single doses of indacaterol in Japanese patients with COPD: a randomized, double-blind, placebo-controlled trial","volume":"59","author":"Kato","year":"2010","journal-title":"Allergol Int"},{"key":"10.1016\/j.rmed.2012.09.002_bib11","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1111\/j.1440-1843.2011.02107.x","article-title":"Efficacy and safety of indacaterol 150 and 300\u03bcg in chronic obstructive pulmonary disease patients from six Asian areas including Japan: a 12-week, placebo controlled study","volume":"17","author":"Kinoshita","year":"2012","journal-title":"Respirology"},{"key":"10.1016\/j.rmed.2012.09.002_bib12","unstructured":"European Medicines Agency (EMA). Onbrez breezhaler (indacaterol) at: http:\/\/www.ema.europa.eu\/ema\/index.jsp?curl=pages\/medicines\/human\/medicines\/001114\/human_med_001219.jsp&murl=menus\/medicines\/medicines.jsp&mid=WC0b01ac058001d124&jsenabled=true (accessed 28.02.12)."},{"key":"10.1016\/j.rmed.2012.09.002_bib13","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1378\/chest.10-1830","article-title":"Long-term safety and efficacy of indacaterol, a novel long-acting \u00df2-agonist, in subjects with COPD: a randomized, placebo-controlled study","volume":"140","author":"Chapman","year":"2011","journal-title":"Chest"},{"key":"10.1016\/j.rmed.2012.09.002_bib14","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1378\/chest.07-3059","article-title":"The many \u201csmall COPDs\u201d: COPD should be an orphan disease","volume":"134","author":"Rennard","year":"2008","journal-title":"Chest"},{"author":"Global Initiative for Chronic Obstructive Lung Disease (GOLD)","key":"10.1016\/j.rmed.2012.09.002_bib15"},{"key":"10.1016\/j.rmed.2012.09.002_bib16","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1081\/COPD-200050666","article-title":"The MCID of the transition dyspnoea index is a total score of one unit","volume":"2","author":"Mahler","year":"2005","journal-title":"COPD"},{"key":"10.1016\/j.rmed.2012.09.002_bib17","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1081\/COPD-200050513","article-title":"St. George's Respiratory Questionnaire: MCID","volume":"2","author":"Jones","year":"2005","journal-title":"COPD"},{"key":"10.1016\/j.rmed.2012.09.002_bib18","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1513\/pats.200601-002SF","article-title":"Improving dyspnea in chronic obstructive pulmonary disease","volume":"3","author":"Rabe","year":"2006","journal-title":"Proc Am Thorac Soc"},{"key":"10.1016\/j.rmed.2012.09.002_bib19","unstructured":"Korn S, Kornmann O, Dunn L, Lassen C, Lawrence D, Kramer B. Efficacy of indacaterol is maintained in patients with moderate or less and severe or worse COPD. In: Presented at European Respiratory Society; 2011. p. 860."},{"key":"10.1016\/j.rmed.2012.09.002_bib20","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/1477-7525-1-18","article-title":"Health-related quality of life, utility, and productivity outcomes instruments: ease of completion by subjects with COPD","volume":"1","author":"Stahl","year":"2003","journal-title":"Health Qual Outcome"},{"key":"10.1016\/j.rmed.2012.09.002_bib21","series-title":"Fundamentals of sleep technology","first-page":"200","article-title":"Cardiopulmonary disorders affecting sleep in the elderly","author":"Gooneratne","year":"2007"},{"issue":"Suppl. S2","key":"10.1016\/j.rmed.2012.09.002_bib22","first-page":"A240","article-title":"Long-term safety and\u00a0tolerability of indacaterol versus salmeterol in Japanese COPD patients: a 52-week open-labeled study","volume":"16","author":"To","year":"2011","journal-title":"Respirology"},{"key":"10.1016\/j.rmed.2012.09.002_bib23","doi-asserted-by":"crossref","first-page":"477","DOI":"10.2147\/COPD.S23816","article-title":"Safety of indacaterol in the treatment of patients with COPD","volume":"6","author":"Donohue","year":"2011","journal-title":"Int J Chron Obstruct Pulmon Dis"}],"container-title":["Respiratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611112003435?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611112003435?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T11:20:08Z","timestamp":1760613608000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0954611112003435"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12]]},"references-count":23,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["S0954611112003435"],"URL":"https:\/\/doi.org\/10.1016\/j.rmed.2012.09.002","relation":{},"ISSN":["0954-6111"],"issn-type":[{"type":"print","value":"0954-6111"}],"subject":[],"published":{"date-parts":[[2012,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Assessing efficacy of indacaterol in moderate and severe COPD patients: A 12-week study in an Asian population","name":"articletitle","label":"Article Title"},{"value":"Respiratory Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rmed.2012.09.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}