{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T20:22:12Z","timestamp":1789417332189,"version":"build-2803163510"},"reference-count":23,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"vor","delay-in-days":730,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","resmedjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Medicine"],"published-print":{"date-parts":[[2013,2]]},"DOI":"10.1016\/j.rmed.2012.10.018","type":"journal-article","created":{"date-parts":[[2012,11,24]],"date-time":"2012-11-24T05:50:46Z","timestamp":1353736246000},"page":"249-255","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":89,"title":["Prevalence and clinical significance of circulating autoantibodies in idiopathic pulmonary fibrosis"],"prefix":"10.1016","volume":"107","author":[{"given":"Joyce S.","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eunice J.","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kara L.","family":"Lynch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brett","family":"Elicker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher J.","family":"Ryerson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamiko R.","family":"Katsumoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony K.","family":"Shum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul J.","family":"Wolters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefania","family":"Cerri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Richeldi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirk D.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Talmadge E.","family":"King","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harold R.","family":"Collard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.rmed.2012.10.018_bib1","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1164\/rccm.2009-040GL","article-title":"An official ATS\/ERS\/JRS\/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management","volume":"183","author":"Raghu","year":"2011","journal-title":"Am J Respir Crit Care Med"},{"issue":"1","key":"10.1016\/j.rmed.2012.10.018_bib2","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1378\/chest.08-2572","article-title":"Pathologic and radiologic differences between idiopathic and collagen vascular disease-related usual interstitial pneumonia","volume":"136","author":"Song","year":"2009","journal-title":"Chest"},{"issue":"5","key":"10.1016\/j.rmed.2012.10.018_bib3","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1378\/chest.130.5.1489","article-title":"Interstitial lung disease in primary Sjogren syndrome","volume":"130","author":"Parambil","year":"2006","journal-title":"Chest"},{"issue":"5","key":"10.1016\/j.rmed.2012.10.018_bib4","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1378\/chest.09-0444","article-title":"Rheumatoid arthritis-associated interstitial lung disease: the relevance of histopathologic and radiographic pattern","volume":"136","author":"Kim","year":"2009","journal-title":"Chest"},{"issue":"2","key":"10.1016\/j.rmed.2012.10.018_bib5","first-page":"121","article-title":"The major histopathologic pattern of pulmonary fibrosis in scleroderma is nonspecific interstitial pneumonia","volume":"19","author":"Kim","year":"2002","journal-title":"Sarcoidosis Vasc Diffuse Lung Dis"},{"issue":"3","key":"10.1016\/j.rmed.2012.10.018_bib6","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1378\/chest.08-0053","article-title":"Clinically significant interstitial lung disease in limited scleroderma: histopathology, clinical features, and survival","volume":"134","author":"Fischer","year":"2008","journal-title":"Chest"},{"issue":"Suppl. 5","key":"10.1016\/j.rmed.2012.10.018_bib7","first-page":"v1","article-title":"Interstitial lung disease guideline: the British Thoracic Society in collaboration with the Thoracic Society of Australia and New Zealand and the Irish Thoracic Society","volume":"63","author":"Bradley","year":"2008","journal-title":"Thorax"},{"key":"10.1016\/j.rmed.2012.10.018_bib8","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1378\/chest.10-2662","article-title":"Autoimmune-featured interstitial lung disease: a distinct entity","volume":"140","author":"Vij","year":"2011","journal-title":"Chest"},{"issue":"3","key":"10.1016\/j.rmed.2012.10.018_bib9","first-page":"381","article-title":"Circulating immune complexes in patients with cryptogenic fibrosing alveolitis","volume":"37","author":"Haslam","year":"1979","journal-title":"Clin Exp Immunol"},{"issue":"8","key":"10.1016\/j.rmed.2012.10.018_bib10","first-page":"1600","article-title":"Anti-th\/to-positivity in a cohort of patients with idiopathic pulmonary fibrosis","volume":"33","author":"Fischer","year":"2006","journal-title":"J Rheumatol"},{"issue":"2 Pt 1","key":"10.1016\/j.rmed.2012.10.018_bib11","first-page":"646","article-title":"Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS)","volume":"161","year":"2000","journal-title":"Am J Respir Crit Care Med"},{"issue":"7","key":"10.1016\/j.rmed.2012.10.018_bib12","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1164\/rccm.200702-220OC","article-title":"Idiopathic nonspecific interstitial pneumonia: lung manifestation of undifferentiated connective tissue disease?","volume":"176","author":"Kinder","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"10.1016\/j.rmed.2012.10.018_bib13","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1373\/clinchem.2009.135087","article-title":"Comparison of multiplex immunoassay platforms","volume":"56","author":"Fu","year":"2010","journal-title":"Clin Chem"},{"issue":"2","key":"10.1016\/j.rmed.2012.10.018_bib14","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1378\/chest.10-0194","article-title":"Connective tissue disease-associated interstitial lung disease: a call for clarification","volume":"138","author":"Fischer","year":"2010","journal-title":"Chest"},{"issue":"3","key":"10.1016\/j.rmed.2012.10.018_bib15","first-page":"557","article-title":"High prevalence of anti-cardiolipin and other autoantibodies in a healthy elderly population","volume":"69","author":"Manoussakis","year":"1987","journal-title":"Clin Exp Immunol"},{"issue":"2","key":"10.1016\/j.rmed.2012.10.018_bib16","first-page":"403","article-title":"Immunological responses of healthy elderly population","volume":"48","author":"Goodwin","year":"1982","journal-title":"Clin Exp Immunol"},{"issue":"2","key":"10.1016\/j.rmed.2012.10.018_bib17","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1159\/000213183","article-title":"Autoantibodies of systemic rheumatic diseases in the healthy elderly","volume":"36","author":"Ruffatti","year":"1990","journal-title":"Gerontology"},{"issue":"2","key":"10.1016\/j.rmed.2012.10.018_bib18","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1002\/hep.1840050204","article-title":"Rheumatoid factor-like reactants in sera proven to transmit non-A, non-B hepatitis: a potential source of false-positive reactions in non-A, non-B assays","volume":"5","author":"Shiraishi","year":"1985","journal-title":"Hepatology"},{"issue":"1","key":"10.1016\/j.rmed.2012.10.018_bib19","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/0166-0934(84)90079-X","article-title":"Specificity and sensitivity of the IgM capture immunoassay: studies of possible factors inducing false positive or false negative results","volume":"9","author":"Briantais","year":"1984","journal-title":"J Virol Methods"},{"issue":"3","key":"10.1016\/j.rmed.2012.10.018_bib20","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1183\/09031936.00174910","article-title":"Significance of connective tissue disease features in idiopathic interstitial pneumonia","volume":"39","author":"Corte","year":"2012","journal-title":"Eur Respir J"},{"issue":"9","key":"10.1016\/j.rmed.2012.10.018_bib21","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1002\/art.1780400909","article-title":"Range of antinuclear antibodies in \u201chealthy\u201d individuals","volume":"40","author":"Tan","year":"1997","journal-title":"Arthritis Rheum"},{"issue":"5","key":"10.1016\/j.rmed.2012.10.018_bib22","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1111\/j.1440-1843.2007.01140.x","article-title":"Autoantibody to alanyl-tRNA synthetase in patients with idiopathic pulmonary fibrosis","volume":"12","author":"Takahashi","year":"2007","journal-title":"Respirology"},{"issue":"11","key":"10.1016\/j.rmed.2012.10.018_bib23","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1016\/j.rmed.2009.05.001","article-title":"Anti-synthetase syndrome in ANA and anti-Jo-1 negative patients presenting with idiopathic interstitial pneumonia","volume":"103","author":"Fischer","year":"2009","journal-title":"Respir Med"}],"container-title":["Respiratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611112004015?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611112004015?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T11:26:41Z","timestamp":1760614001000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0954611112004015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2]]},"references-count":23,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["S0954611112004015"],"URL":"https:\/\/doi.org\/10.1016\/j.rmed.2012.10.018","relation":{},"ISSN":["0954-6111"],"issn-type":[{"value":"0954-6111","type":"print"}],"subject":[],"published":{"date-parts":[[2013,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prevalence and clinical significance of circulating autoantibodies in idiopathic pulmonary fibrosis","name":"articletitle","label":"Article Title"},{"value":"Respiratory Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rmed.2012.10.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}