{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T23:22:27Z","timestamp":1791069747498,"version":"4.1.0"},"reference-count":41,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2014,2,1]],"date-time":"2014-02-01T00:00:00Z","timestamp":1391212800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,2,1]],"date-time":"2014-02-01T00:00:00Z","timestamp":1391212800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"vor","delay-in-days":730,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","resmedjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Medicine"],"published-print":{"date-parts":[[2014,2]]},"DOI":"10.1016\/j.rmed.2013.12.015","type":"journal-article","created":{"date-parts":[[2014,1,8]],"date-time":"2014-01-08T01:01:09Z","timestamp":1389142869000},"page":"287-296","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":174,"title":["Mortality in non-cystic fibrosis bronchiectasis: A prospective cohort analysis"],"prefix":"10.1016","volume":"108","author":[{"given":"P.C.","family":"Goeminne","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.S.","family":"Nawrot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Ruttens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Seys","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.J.","family":"Dupont","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.rmed.2013.12.015_bib1","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1136\/pgmj.2009.091041","article-title":"Non-cystic fibrosis bronchiectasis: diagnosis and management in 21st century","volume":"86","author":"Goeminne","year":"2010","journal-title":"Postgrad Med J"},{"key":"10.1016\/j.rmed.2013.12.015_bib2","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1136\/thoraxjnl-2012-202893","article-title":"Research priorities in bronchiectasis","volume":"68","author":"De Soyza","year":"2013","journal-title":"Thorax"},{"key":"10.1016\/j.rmed.2013.12.015_bib3","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/j.rmed.2010.02.022","article-title":"Trends in bronchiectasis mortality in England and Wales","volume":"104","author":"Roberts","year":"2010","journal-title":"Respir Med"},{"key":"10.1016\/j.rmed.2013.12.015_bib4","doi-asserted-by":"crossref","first-page":"1815","DOI":"10.1378\/chest.125.5.1815","article-title":"Survival of patients with bronchiectasis after the first ICU stay for respiratory failure","volume":"125","author":"Dupont","year":"2004","journal-title":"Chest"},{"key":"10.1016\/j.rmed.2013.12.015_bib5","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/j.rmed.2009.11.021","article-title":"Predictors of mortality in hospitalized patients with acute exacerbation of bronchiectasis","volume":"104","author":"Finklea","year":"2010","journal-title":"Respir Med"},{"key":"10.1016\/j.rmed.2013.12.015_bib6","doi-asserted-by":"crossref","first-page":"e129","DOI":"10.1111\/j.1445-5994.2011.02444.x","article-title":"Socioeconomic deprivation, readmissions, mortality and acute exacerbations of bronchiectasis","volume":"42","author":"Roberts","year":"2012","journal-title":"Intern Med J"},{"key":"10.1016\/j.rmed.2013.12.015_bib7","doi-asserted-by":"crossref","first-page":"2784","DOI":"10.1183\/09031936.97.10122784","article-title":"Bronchiectasis: an orphan disease with a poorly-understood prognosis","volume":"10","author":"Keistinen","year":"1997","journal-title":"Eur Respir J"},{"key":"10.1016\/j.rmed.2013.12.015_bib8","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/1465-9921-13-21","article-title":"Risk factors for morbidity and death in non-cystic fibrosis bronchiectasis: a retrospective cross-sectional analysis of CT diagnosed bronchiectatic patients","volume":"13","author":"Goeminne","year":"2012","journal-title":"Respir Res"},{"key":"10.1016\/j.rmed.2013.12.015_bib9","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1183\/09031936.00003709","article-title":"Mortality in bronchiectasis: a long-term study assessing the factors influencing survival","volume":"34","author":"Loebinger","year":"2009","journal-title":"Eur Respir J"},{"key":"10.1016\/j.rmed.2013.12.015_bib10","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1016\/j.rmed.2007.02.002","article-title":"Analysis of the factors related to mortality in patients with bronchiectasis","volume":"101","author":"Onen","year":"2007","journal-title":"Respir Med"},{"key":"10.1016\/j.rmed.2013.12.015_bib11","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.jpeds.2004.02.038","article-title":"High-resolution computed tomography in young patients with cystic fibrosis: distribution of abnormalities and correlation with pulmonary function tests","volume":"145","author":"Brody","year":"2004","journal-title":"J Pediatr"},{"key":"10.1016\/j.rmed.2013.12.015_bib12","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S1569-1993(02)00141-8","article-title":"Evaluation of a new definition for chronic Pseudomonas aeruginosa infection in cystic fibrosis patients","volume":"2","author":"Lee","year":"2003","journal-title":"J Cyst Fibros"},{"key":"10.1016\/j.rmed.2013.12.015_bib13","doi-asserted-by":"crossref","first-page":"2493","DOI":"10.1093\/eurheartj\/ehp297","volume":"30","author":"Galie","year":"2009","journal-title":"Eur Heart J"},{"key":"10.1016\/j.rmed.2013.12.015_bib14","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1183\/09031936.05.00034505","article-title":"General considerations for lung function testing","volume":"26","author":"Miller","year":"2005","journal-title":"Eur Respir J"},{"key":"10.1016\/j.rmed.2013.12.015_bib15","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1183\/09031936.05.00034805","article-title":"Standardisation of spirometry","volume":"26","author":"Miller","year":"2005","journal-title":"Eur Respir J"},{"key":"10.1016\/j.rmed.2013.12.015_bib16","unstructured":"Federale Overheidsdienst Economie (FOD), Algmene Directie Statistiek en Economische Informatie (ADSEI) http:\/\/statbel.fgov.be\/nl\/statistieken\/cijfers\/bevolking\/sterfte_leven\/sterfte\/."},{"key":"10.1016\/j.rmed.2013.12.015_bib17","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1046\/j.0306-5251.2001.01401.x","article-title":"Drug therapy in the elderly: what doctors believe and patients actually do","volume":"51","author":"Barat","year":"2001","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.rmed.2013.12.015_bib18","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1111\/j.1365-2710.2011.01300.x","article-title":"Discontinuation of angiotensin-converting enzyme inhibitors: a cohort study","volume":"37","author":"Wong","year":"2012","journal-title":"J Clin Pharm Ther"},{"key":"10.1016\/j.rmed.2013.12.015_bib19","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1378\/chest.10-1758","article-title":"Factors associated with bronchiectasis in patients with COPD","volume":"140","author":"Martinez-Garcia","year":"2011","journal-title":"Chest"},{"key":"10.1016\/j.rmed.2013.12.015_bib20","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1097\/MCP.0b013e32835d8312","article-title":"Chronic obstructive pulmonary disease and bronchiectasis","volume":"19","author":"Novosad","year":"2013","journal-title":"Curr Opin Pulm Med"},{"key":"10.1016\/j.rmed.2013.12.015_bib21","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1378\/chest.11-1484","article-title":"Bronchiectasis in patients with COPD: a distinct COPD phenotype?","volume":"140","author":"O'Donnell","year":"2011","journal-title":"Chest"},{"key":"10.1016\/j.rmed.2013.12.015_bib22","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1136\/thorax.55.8.635","article-title":"Physiological and radiological characterisation of patients diagnosed with chronic obstructive pulmonary disease in primary care","volume":"55","author":"O'Brien","year":"2000","journal-title":"Thorax"},{"key":"10.1016\/j.rmed.2013.12.015_bib23","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1164\/rccm.200305-648OC","article-title":"Bronchiectasis, exacerbation indices, and inflammation in chronic obstructive pulmonary disease","volume":"170","author":"Patel","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.rmed.2013.12.015_bib24","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1164\/rccm.201208-1518OC","article-title":"Prognostic value of bronchiectasis in patients with moderate-to-severe chronic obstructive pulmonary disease","volume":"187","author":"Martinez-Garcia","year":"2013","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.rmed.2013.12.015_bib25","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1093\/rheumatology\/36.6.689","article-title":"Decreased survival in patients with co-existent rheumatoid arthritis and bronchiectasis","volume":"36","author":"Swinson","year":"1997","journal-title":"Br J Rheumatol"},{"key":"10.1016\/j.rmed.2013.12.015_bib26","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/s10067-011-1849-4","article-title":"Safety of immunomodulatory therapy in patients with bronchiectasis associated with rheumatic disease and IBD: a retrospective and cohort analysis","volume":"31","author":"Goeminne","year":"2012","journal-title":"Clin Rheumatol"},{"key":"10.1016\/j.rmed.2013.12.015_bib27","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1183\/09031936.06.00074605","article-title":"The effect of Pseudomonas aeruginosa on pulmonary function in patients with bronchiectasis","volume":"28","author":"Davies","year":"2006","journal-title":"Eur Respir J"},{"key":"10.1016\/j.rmed.2013.12.015_bib28","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1183\/09031936.97.10081754","article-title":"Effect of sputum bacteriology on the quality of life of patients with bronchiectasis","volume":"10","author":"Wilson","year":"1997","journal-title":"Eur Respir J"},{"key":"10.1016\/j.rmed.2013.12.015_bib29","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1378\/chest.07-0490","article-title":"Factors associated with lung function decline in adult patients with stable non-cystic fibrosis bronchiectasis","volume":"132","author":"Martinez-Garcia","year":"2007","journal-title":"Chest"},{"key":"10.1016\/j.rmed.2013.12.015_bib30","article-title":"The sputum colour chart as a predictor of lung inflammation, proteolysis and damage in non-cystic fibrosis bronchiectasis: a case-control analysis","author":"Goeminne","year":"2013","journal-title":"Respirology"},{"key":"10.1016\/j.rmed.2013.12.015_bib31","doi-asserted-by":"crossref","unstructured":"Mart\u00ednez-Garc\u00eda MA, de Gracia J, Vendrell Relat M, et\u00a0al. Multidimensional approach to non-cystic fibrosis bronchiectasis. The FACED score. Eur Respir J. http:\/\/dx.doi.org\/10.1183\/09031936.00026313 [Epub ahead of print].","DOI":"10.1183\/09031936.00026313"},{"key":"10.1016\/j.rmed.2013.12.015_bib32","article-title":"The bronchiectasis severity Index: an international derivation and validation study","author":"Chalmers","year":"2013","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.rmed.2013.12.015_bib33","article-title":"Molecular epidemiological analysis suggests cross infection with Pseudomonas aeruginosa is rare in non-cystic fibrosis bronchiectasis","author":"De Soyza","year":"2013","journal-title":"Eur Respir J"},{"key":"10.1016\/j.rmed.2013.12.015_bib34","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.2214\/AJR.10.5221","article-title":"Pulmonary hypertension in patients with bronchiectasis: prognostic significance of CT signs","volume":"196","author":"Devaraj","year":"2011","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.rmed.2013.12.015_bib35","article-title":"Clinical characteristics\u00a0and prediction of pulmonary hypertension in\u00a0severe emphysema","author":"Minai","year":"2013","journal-title":"Respir Med"},{"key":"10.1016\/j.rmed.2013.12.015_bib36","doi-asserted-by":"crossref","first-page":"39S","DOI":"10.1378\/chest.10-0087","article-title":"Pulmonary hypertension in COPD: epidemiology, significance, and management","volume":"137","author":"Minai","year":"2010","journal-title":"Chest"},{"key":"10.1016\/j.rmed.2013.12.015_bib37","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1378\/chest.07-1639","article-title":"Right and left ventricular function and pulmonary artery pressure in patients with bronchiectasis","volume":"133","author":"Alzeer","year":"2008","journal-title":"Chest"},{"key":"10.1016\/j.rmed.2013.12.015_bib38","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1016\/j.rmed.2008.06.005","article-title":"Effects of long-term low-dose azithromycin in patients with non-CF bronchiectasis","volume":"102","author":"Anwar","year":"2008","journal-title":"Respir Med"},{"key":"10.1016\/j.rmed.2013.12.015_bib39","first-page":"338","article-title":"Effect of macrolide on lung function and computed tomography (CT) score in non-cystic fibrosis bronchiectasis","volume":"67","author":"Goeminne","year":"2012","journal-title":"Acta Clin Belg"},{"key":"10.1016\/j.rmed.2013.12.015_bib40","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1016\/S0140-6736(12)60953-2","article-title":"Azithromycin for prevention of exacerbations in non-cystic fibrosis bronchiectasis (EMBRACE): a randomised, double-blind, placebo-controlled trial","volume":"380","author":"Wong","year":"2012","journal-title":"Lancet"},{"key":"10.1016\/j.rmed.2013.12.015_bib41","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1001\/jama.2013.1937","article-title":"Effect of azithromycin maintenance treatment on infectious exacerbations among patients with non-cystic fibrosis bronchiectasis: the BAT randomized controlled trial","volume":"309","author":"Altenburg","year":"2013","journal-title":"JAMA"}],"container-title":["Respiratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611113005015?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611113005015?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T11:29:54Z","timestamp":1760614194000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0954611113005015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2]]},"references-count":41,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,2]]}},"alternative-id":["S0954611113005015"],"URL":"https:\/\/doi.org\/10.1016\/j.rmed.2013.12.015","relation":{},"ISSN":["0954-6111"],"issn-type":[{"value":"0954-6111","type":"print"}],"subject":[],"published":{"date-parts":[[2014,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mortality in non-cystic fibrosis bronchiectasis: A prospective cohort analysis","name":"articletitle","label":"Article Title"},{"value":"Respiratory Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rmed.2013.12.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}