{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T08:01:56Z","timestamp":1776585716873,"version":"3.51.2"},"reference-count":15,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2014,6,1]],"date-time":"2014-06-01T00:00:00Z","timestamp":1401580800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,6,1]],"date-time":"2014-06-01T00:00:00Z","timestamp":1401580800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"vor","delay-in-days":731,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","resmedjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Medicine"],"published-print":{"date-parts":[[2014,6]]},"DOI":"10.1016\/j.rmed.2014.03.009","type":"journal-article","created":{"date-parts":[[2014,4,2]],"date-time":"2014-04-02T11:30:45Z","timestamp":1396438245000},"page":"931-934","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Primary ciliary dyskinesia and humoral immunodeficiency \u2013 Is there a missing link?"],"prefix":"10.1016","volume":"108","author":[{"given":"Mieke","family":"Boon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kris","family":"De Boeck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Jorissen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle","family":"Meyts","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.rmed.2014.03.009_bib1","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/s00431-012-1785-6","article-title":"Primary ciliary dyskinesia, an orphan disease","volume":"172","author":"Boon","year":"2013","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.rmed.2014.03.009_bib2","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S0140-6736(08)61199-X","article-title":"Common variable immunodeficiency: a new look at an old disease","volume":"372","author":"Park","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.rmed.2014.03.009_bib3","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1007\/s11882-002-0067-1","article-title":"Immunoglobulin G subclass deficiency: fact or fancy?","volume":"2","author":"Buckley","year":"2002","journal-title":"Curr Allergy Asthma Rep"},{"key":"10.1016\/j.rmed.2014.03.009_bib4","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1203\/00006450-199001000-00004","article-title":"Clinical and immunologic characteristics of healthy children with subnormal serum concentrations of IgG2","volume":"27","author":"Shackelford","year":"1990","journal-title":"Pediatr Res"},{"key":"10.1016\/j.rmed.2014.03.009_bib5","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/j.jaci.2013.02.028","article-title":"Controversies in IgG replacement therapy in patients with antibody deficiency diseases","volume":"131","author":"Gelfand","year":"2013","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.rmed.2014.03.009_bib6","doi-asserted-by":"crossref","first-page":"e1203","DOI":"10.1542\/peds.2006-2396","article-title":"Diagnosis of common variable immunodeficiency in a patient with primary ciliary dyskinesia","volume":"119","author":"Skorpinski","year":"2007","journal-title":"Pediatrics"},{"key":"10.1016\/j.rmed.2014.03.009_bib7","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1080\/000164800750001116","article-title":"Ciliary function analysis for the diagnosis of primary ciliary dyskinesia: advantages of ciliogenesis in culture","volume":"120","author":"Jorissen","year":"2000","journal-title":"Acta Otolaryngol"},{"key":"10.1016\/j.rmed.2014.03.009_bib8","first-page":"960","article-title":"Rapid diagnosis of primary ciliary dyskinesia: cell culture and soft computing analysis","volume":"41","author":"Pifferi","year":"2013","journal-title":"Eur Respir J Off J Eur Soc Clin Respir Physiol"},{"key":"10.1016\/j.rmed.2014.03.009_bib9","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.jaci.2012.07.002","article-title":"Use and interpretation of diagnostic vaccination in primary immunodeficiency: a working group report of the Basic and Clinical Immunology Interest Section of the American Academy of Allergy, Asthma & Immunology","volume":"130","author":"Orange","year":"2012","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.rmed.2014.03.009_bib10","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.it.2011.02.001","article-title":"Intraflagellar transport: a new player at the immune synapse","volume":"32","author":"Finetti","year":"2011","journal-title":"Trends Immunol"},{"key":"10.1016\/j.rmed.2014.03.009_bib11","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1165\/ajrcmb\/3.5.431","article-title":"Human ciliated bronchial epithelial cells: expression of the HLA-DR antigens and of the HLA-DR alpha gene, modulation of the HLA-DR antigens by gamma-interferon and antigen-presenting function in the mixed leukocyte reaction","volume":"3","author":"Rossi","year":"1990","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.rmed.2014.03.009_bib12","doi-asserted-by":"crossref","first-page":"e55472","DOI":"10.1371\/journal.pone.0055472","article-title":"Activated human nasal epithelial cells modulate specific antibody response against bacterial or viral antigens","volume":"8","author":"Yeh","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.rmed.2014.03.009_bib13","first-page":"572","article-title":"Nasal nitric oxide and nitric oxide synthase expression in primary ciliary dyskinesia","volume":"37","author":"Pifferi","year":"2011","journal-title":"Eur Respir J Off J Eur Soc Clin Respir Physiol"},{"key":"10.1016\/j.rmed.2014.03.009_bib14","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1038\/nature06033","article-title":"Regulation of IgA production by naturally occurring TNF\/iNOS-producing dendritic cells","volume":"448","author":"Tezuka","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.rmed.2014.03.009_bib15","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1136\/thx.2007.083147","article-title":"Diagnosing primary ciliary dyskinesia","volume":"62","author":"O'Callaghan","year":"2007","journal-title":"Thorax"}],"container-title":["Respiratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611114001188?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611114001188?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T11:30:42Z","timestamp":1760614242000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0954611114001188"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["S0954611114001188"],"URL":"https:\/\/doi.org\/10.1016\/j.rmed.2014.03.009","relation":{},"ISSN":["0954-6111"],"issn-type":[{"value":"0954-6111","type":"print"}],"subject":[],"published":{"date-parts":[[2014,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Primary ciliary dyskinesia and humoral immunodeficiency \u2013 Is there a missing link?","name":"articletitle","label":"Article Title"},{"value":"Respiratory Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rmed.2014.03.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}