{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:06:32Z","timestamp":1787317592059,"version":"build-2736575974"},"reference-count":37,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2015,3,1]],"date-time":"2015-03-01T00:00:00Z","timestamp":1425168000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,3,1]],"date-time":"2015-03-01T00:00:00Z","timestamp":1425168000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"vor","delay-in-days":731,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","resmedjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Medicine"],"published-print":{"date-parts":[[2015,3]]},"DOI":"10.1016\/j.rmed.2015.01.011","type":"journal-article","created":{"date-parts":[[2015,1,31]],"date-time":"2015-01-31T00:28:43Z","timestamp":1422664123000},"page":"397-405","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Influence of autoimmune biomarkers on interstitial lung diseases: A tertiary referral center based case-control study"],"prefix":"10.1016","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8429-3581","authenticated-orcid":false,"given":"Philippe R.","family":"Bauer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay","family":"Kalra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas G.","family":"Osborn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"St. Sauver","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew C.","family":"Hanson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darrell R.","family":"Schroeder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay H.","family":"Ryu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.rmed.2015.01.011_bib1","doi-asserted-by":"crossref","first-page":"976","DOI":"10.4065\/82.8.976","article-title":"Diagnosis of interstitial lung diseases","volume":"82","author":"Ryu","year":"2007","journal-title":"Mayo Clin Proc"},{"issue":"129","key":"10.1016\/j.rmed.2015.01.011_bib2","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1183\/09059180.00003013","article-title":"Significance of connective tissue diseases features in pulmonary fibrosis","volume":"22","author":"Cottin","year":"2013","journal-title":"Eur Respir Rev"},{"key":"10.1016\/j.rmed.2015.01.011_bib3","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1164\/ajrccm.156.2.9609016","article-title":"Interstitial lung disease in recent onset rheumatoid arthritis","volume":"156","author":"Gabbay","year":"1997","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.rmed.2015.01.011_bib4","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1136\/ard.2003.006122","article-title":"Interstitial lung disease, a common manifestation of newly diagnosed polymyositis and dermatomyositis","volume":"63","author":"Fathi","year":"2004","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.rmed.2015.01.011_bib5","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1097\/01.bor.0000179949.65895.53","article-title":"Interstitial lung disease in polymyositis and dermatomyositis","volume":"17","author":"Fathi","year":"2005","journal-title":"Curr Opin Rheumatol"},{"key":"10.1016\/j.rmed.2015.01.011_bib6","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1097\/00005792-200203000-00004","article-title":"Systemic sclerosis: demographic, clinical, and serologic features and survival in 1,012 Italian patients","volume":"81","author":"Ferri","year":"2002","journal-title":"Med Baltim"},{"key":"10.1016\/j.rmed.2015.01.011_bib7","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/S0272-5231(05)70108-8","article-title":"Pulmonary manifestations of systemic lupus erythematosus","volume":"19","author":"Murin","year":"1998","journal-title":"Clin Chest Med"},{"issue":"3","key":"10.1016\/j.rmed.2015.01.011_bib8","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.ccm.2004.05.009","article-title":"Interstitial lung disease in the patient who has connective tissue disease","volume":"25","author":"Strange","year":"2004","journal-title":"Clin Chest Med"},{"key":"10.1016\/j.rmed.2015.01.011_bib9","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.4065\/77.11.1221","article-title":"Diagnostic approach to the patient with diffuse lung disease","volume":"77","author":"Ryu","year":"2002","journal-title":"Mayo Clin Proc"},{"issue":"3","key":"10.1016\/j.rmed.2015.01.011_bib10","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1378\/chest.12-0741","article-title":"Diagnosis and treatment of connective tissue disease-associated interstitial lung disease","volume":"143","author":"Vij","year":"2013","journal-title":"Chest"},{"issue":"1","key":"10.1016\/j.rmed.2015.01.011_bib11","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1183\/09031936.00060107","article-title":"Occult connective tissue diseases mimicking idiopathic interstitial pneumonias","volume":"31","author":"Tzelepis","year":"2008","journal-title":"Eur Respir J"},{"issue":"5","key":"10.1016\/j.rmed.2015.01.011_bib12","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1378\/chest.10-2662","article-title":"Autoimmune-featured interstitial lung disease: a distinct entity","volume":"140","author":"Vij","year":"2011","journal-title":"Chest"},{"issue":"2","key":"10.1016\/j.rmed.2015.01.011_bib13","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1378\/chest.10-0194","article-title":"Connective tissue disease-associated interstitial lung disease: a call for clarification","volume":"138","author":"Fischer","year":"2010","journal-title":"Chest"},{"issue":"7","key":"10.1016\/j.rmed.2015.01.011_bib14","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1164\/rccm.200702-220OC","article-title":"Idiopathic nonspecific interstitial pneumonia: lung manifestation of undifferentiated connective tissue disease?","volume":"176","author":"Kinder","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"issue":"9842","key":"10.1016\/j.rmed.2015.01.011_bib15","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/S0140-6736(12)61079-4","article-title":"Interstitial lung disease in connective tissue disorders","volume":"380","author":"Fisher","year":"2012","journal-title":"Lancet"},{"issue":"5","key":"10.1016\/j.rmed.2015.01.011_bib16","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1097\/MCP.0b013e3283560840","article-title":"Serologic evaluation in idiopathic interstitial pneumonias","volume":"18","author":"Papiris","year":"2012","journal-title":"Curr Opin Pulm Med"},{"issue":"11","key":"10.1016\/j.rmed.2015.01.011_bib17","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1016\/j.rmed.2012.07.009","article-title":"Comparison of three groups of patients with usual interstitial pneumonia","volume":"106","author":"Alhamad","year":"2012","journal-title":"Respir Med"},{"issue":"2","key":"10.1016\/j.rmed.2015.01.011_bib18","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1378\/chest.12-2768","article-title":"Influence of interstitial lung disease on outcome in systemic sclerosis: a population-based historical cohort study","volume":"144","author":"Bauer","year":"2013","journal-title":"Chest"},{"issue":"2","key":"10.1016\/j.rmed.2015.01.011_bib19","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1164\/ajrccm.165.2.ats01","volume":"165","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"issue":"6","key":"10.1016\/j.rmed.2015.01.011_bib20","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1164\/rccm.201308-1483ST","article-title":"An official American Thoracic Society\/European Respiratory Society statement: update of the international multidisciplinary classification of the idiopathic interstitial pneumonias","volume":"188","author":"Travis","year":"2013","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.rmed.2015.01.011_bib21","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1007\/s13665-012-0028-7","article-title":"Connective tissue disease-associated interstitial lung disease: a review","volume":"1","author":"Gutsche","year":"2012","journal-title":"Curr Respir Care Rep"},{"key":"10.1016\/j.rmed.2015.01.011_bib22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.autrev.2006.03.004","article-title":"Undifferentiated connective tissue diseases (UCTD)","volume":"6","author":"Mosca","year":"2006","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.rmed.2015.01.011_bib23","unstructured":"Rollin Brant. Unmatched case\/control studies. http:\/\/www.stat.ubc.ca\/\u223crollin\/stats\/ssize\/caco.html . Accessed online October 28, 2013."},{"issue":"2","key":"10.1016\/j.rmed.2015.01.011_bib24","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1136\/thorax.58.2.143","article-title":"Radiological versus histological diagnosis in UIP and NSIP: survival implications","volume":"58","author":"Flaherty","year":"2003","journal-title":"Thorax"},{"issue":"1","key":"10.1016\/j.rmed.2015.01.011_bib25","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1177\/1479972310393758","article-title":"Review series: aspects of interstitial lung disease: connective tissue disease-associated interstitial lung disease: how does it differ from IPF? How should the clinical approach differ?","volume":"8","author":"de Lauretis","year":"2011","journal-title":"Chron Respir Dis"},{"issue":"2","key":"10.1016\/j.rmed.2015.01.011_bib26","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/s00408-009-9226-7","article-title":"Undifferentiated connective tissue disease-associated interstitial lung disease: changes in lung function","volume":"188","author":"Kinder","year":"2010","journal-title":"Lung"},{"issue":"10","key":"10.1016\/j.rmed.2015.01.011_bib27","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1016\/j.rmed.2010.04.022","article-title":"Distinct prognosis of idiopathic nonspecific interstitial pneumonia (NSIP) fulfilling criteria for undifferentiated connective tissue disease (UCTD)","volume":"104","author":"Suda","year":"2010","journal-title":"Respir Med"},{"issue":"3","key":"10.1016\/j.rmed.2015.01.011_bib28","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1183\/09031936.00174910","article-title":"Significance of connective tissue disease features in idiopathic interstitial pneumonia","volume":"39","author":"Corte","year":"2012","journal-title":"Eur Respir J"},{"issue":"2","key":"10.1016\/j.rmed.2015.01.011_bib29","first-page":"107","article-title":"Immunological studies in human ageing. II. Associated increase in anti-RNA and anti-DNA antibodies","volume":"6","author":"Schuller","year":"1981","journal-title":"J Clin Lab Immunol"},{"issue":"7","key":"10.1016\/j.rmed.2015.01.011_bib30","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1164\/rccm.200602-163OC","article-title":"Incidence and prevalence of idiopathic pulmonary fibrosis","volume":"174","author":"Raghu","year":"2006","journal-title":"Am J Respir Crit Care Med"},{"issue":"3","key":"10.1016\/j.rmed.2015.01.011_bib31","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.mayocp.2013.11.018","article-title":"Frequency and implication of autoimmune serologies in idiopathic pulmonary fibrosis","volume":"89","author":"Moua","year":"2014","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.rmed.2015.01.011_bib32","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/1471-2466-13-31","article-title":"Increased incidence of autoimmune markers in patients with combined pulmonary fibrosis and emphysema","volume":"13","author":"Tzouvelekis","year":"2013","journal-title":"BMC Pulm Med"},{"issue":"10","key":"10.1016\/j.rmed.2015.01.011_bib33","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1136\/thx.2004.031021","article-title":"Challenges in pulmonary fibrosis. 4: smoking-induced diffuse interstitial lung diseases","volume":"62","author":"Wells","year":"2007","journal-title":"Thorax"},{"issue":"5","key":"10.1016\/j.rmed.2015.01.011_bib34","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1055\/s-0032-1325158","article-title":"Acute interstitial pneumonia (AIP): relationship to hamman-rich syndrome, diffuse alveolar damage (DAD), and acute respiratory distress syndrome (ARDS)","volume":"33","author":"Mukhopadhyay","year":"2012","journal-title":"Semin Respir Crit Care Med"},{"issue":"8","key":"10.1016\/j.rmed.2015.01.011_bib35","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1016\/j.rmed.2009.02.009","article-title":"Ascertainment of collagen vascular disease in patients presenting with interstitial lung disease","volume":"103","author":"Mittoo","year":"2009","journal-title":"Respir Med"},{"issue":"4","key":"10.1016\/j.rmed.2015.01.011_bib36","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1002\/art.21322","article-title":"Comparison of disease progression and mortality of connective tissue disease-related interstitial lung disease and idiopathic interstitial pneumonia","volume":"53","author":"Kocheril","year":"2005","journal-title":"Arthritis Rheum"},{"issue":"4","key":"10.1016\/j.rmed.2015.01.011_bib37","doi-asserted-by":"crossref","first-page":"693","DOI":"10.3899\/jrheum.100675","article-title":"An analysis of connective tissue disease-associated interstitial lung disease at a US tertiary care center: better survival in patients with systemic sclerosis","volume":"38","author":"Su","year":"2011","journal-title":"J Rheumatol"}],"container-title":["Respiratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611115000141?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611115000141?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T11:31:34Z","timestamp":1760614294000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0954611115000141"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["S0954611115000141"],"URL":"https:\/\/doi.org\/10.1016\/j.rmed.2015.01.011","relation":{},"ISSN":["0954-6111"],"issn-type":[{"value":"0954-6111","type":"print"}],"subject":[],"published":{"date-parts":[[2015,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Influence of autoimmune biomarkers on interstitial lung diseases: A tertiary referral center based case-control study","name":"articletitle","label":"Article Title"},{"value":"Respiratory Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rmed.2015.01.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}