{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T16:06:16Z","timestamp":1768838776916,"version":"3.49.0"},"reference-count":17,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2015,6,1]],"date-time":"2015-06-01T00:00:00Z","timestamp":1433116800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,6,1]],"date-time":"2015-06-01T00:00:00Z","timestamp":1433116800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"vor","delay-in-days":731,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","resmedjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Medicine"],"published-print":{"date-parts":[[2015,6]]},"DOI":"10.1016\/j.rmed.2015.02.013","type":"journal-article","created":{"date-parts":[[2015,3,6]],"date-time":"2015-03-06T05:39:20Z","timestamp":1425620360000},"page":"734-742","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Adrenomedullin optimises mortality prediction in COPD patients"],"prefix":"10.1016","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1781-5794","authenticated-orcid":false,"given":"Marjolein","family":"Brusse-Keizer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maaike","family":"Zuur-Telgen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Job","family":"van der Palen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"VanderValk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huib","family":"Kerstjens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wim","family":"Boersma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Blasi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0774-3942","authenticated-orcid":false,"given":"Konstantinos","family":"Kostikas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Branislava","family":"Milenkovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Tamm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daiana","family":"Stolz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.rmed.2015.02.013_bib1","series-title":"Global strategy for the diagnosis, management and prevention of COPD, global initiative for chornic obstructive pulmonary disease (GOLD) 2013","year":"2013"},{"issue":"10","key":"10.1016\/j.rmed.2015.02.013_bib2","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1056\/NEJMoa021322","article-title":"The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease","volume":"350","author":"Celli","year":"2004","journal-title":"N Engl J Med"},{"issue":"6","key":"10.1016\/j.rmed.2015.02.013_bib3","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2012-002152","article-title":"Large-scale international validation of the ADO index in subjects with COPD: an individual subject data analysis of 10 cohorts","volume":"2","author":"Puhan","year":"2012","journal-title":"BMJ Open"},{"issue":"9691","key":"10.1016\/j.rmed.2015.02.013_bib4","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1016\/S0140-6736(09)61301-5","article-title":"Expansion of the prognostic assessment of patients with chronic obstructive pulmonary disease: the updated BODE index and the ADO index","volume":"374","author":"Puhan","year":"2009","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.rmed.2015.02.013_bib5","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1164\/rccm.201201-0034OC","article-title":"Comorbidities and risk of mortality in patients with chronic obstructive pulmonary disease","volume":"186","author":"Divo","year":"2012","journal-title":"Am J Respir Crit Care Med"},{"issue":"Suppl. 52","key":"10.1016\/j.rmed.2015.02.013_bib6","first-page":"42S","article-title":"The multidimensional BOD: association with mortality in the TORCH trial","volume":"32","author":"Celli","year":"2008","journal-title":"Eur Respir J"},{"issue":"2","key":"10.1016\/j.rmed.2015.02.013_bib7","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1183\/09031936.00058713","article-title":"Adrenomedullin refines mortality prediction by the BODE index in COPD: the \u201cBODE-A\u201d index","volume":"43","author":"Stolz","year":"2014","journal-title":"Eur Respir J"},{"issue":"2","key":"10.1016\/j.rmed.2015.02.013_bib8","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1378\/chest.08-0047","article-title":"Plasma pro-adrenomedullin but not plasma pro-endothelin predicts survival in exacerbations of COPD","volume":"134","author":"Stolz","year":"2008","journal-title":"Chest"},{"key":"10.1016\/j.rmed.2015.02.013_bib9","article-title":"Stable state MR-proadrenomedullin level is a strong predictor for mortality in COPD patients","author":"Zuur-Telgen","year":"2013","journal-title":"Chest"},{"issue":"1","key":"10.1016\/j.rmed.2015.02.013_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1183\/09031936.05.00034205","article-title":"Coming together: the ATS\/ERS consensus on clinical pulmonary function testing","volume":"26","author":"Brusasco","year":"2005","journal-title":"Eur Respir J"},{"issue":"5","key":"10.1016\/j.rmed.2015.02.013_bib11","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1093\/eurjhf\/hfq031","article-title":"Mid-regional pro-adrenomedullin as a novel predictor of mortality in patients with chronic heart failure","volume":"12","author":"von Haehling","year":"2010","journal-title":"Eur J Heart Fail"},{"issue":"10","key":"10.1016\/j.rmed.2015.02.013_bib12","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/S0024-3205(99)00358-6","article-title":"Adrenomedullin: potential in physiology and pathophysiology","volume":"66","author":"Jougasaki","year":"2000","journal-title":"Life Sci"},{"issue":"2","key":"10.1016\/j.rmed.2015.02.013_bib13","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1515\/CCLM.2008.040","article-title":"Long-term prognostic value of mid-regional pro-adrenomedullin and C-terminal pro-endothelin-1 in patients with acute myocardial infarction","volume":"46","author":"Behnes","year":"2008","journal-title":"Clin Chem Lab Med"},{"issue":"14","key":"10.1016\/j.rmed.2015.02.013_bib14","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1016\/j.jacc.2006.12.038","article-title":"Prognostic value of midregional pro-adrenomedullin in patients with acute myocardial infarction: the LAMP (Leicester acute myocardial infarction Peptide) study","volume":"49","author":"Khan","year":"2007","journal-title":"J Am Coll Cardiol"},{"issue":"3","key":"10.1016\/j.rmed.2015.02.013_bib15","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1378\/chest.93.3.580","article-title":"Evaluation of clinical methods for rating dyspnea","volume":"93","author":"Mahler","year":"1988","journal-title":"Chest"},{"issue":"5","key":"10.1016\/j.rmed.2015.02.013_bib16","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1183\/09031936.00080411","article-title":"Prognostic power of proadrenomedullin in community-acquired pneumonia is independent of aetiology","volume":"39","author":"Bello","year":"2012","journal-title":"Eur Respir J"},{"issue":"3","key":"10.1016\/j.rmed.2015.02.013_bib17","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1007\/s00134-007-0955-x","article-title":"The influence of corticosteroids on the release of novel biomarkers in human endotoxemia","volume":"34","author":"de Kruif","year":"2008","journal-title":"Intensive Care Med"}],"container-title":["Respiratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611115000761?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611115000761?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T11:32:56Z","timestamp":1760614376000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0954611115000761"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,6]]}},"alternative-id":["S0954611115000761"],"URL":"https:\/\/doi.org\/10.1016\/j.rmed.2015.02.013","relation":{},"ISSN":["0954-6111"],"issn-type":[{"value":"0954-6111","type":"print"}],"subject":[],"published":{"date-parts":[[2015,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adrenomedullin optimises mortality prediction in COPD patients","name":"articletitle","label":"Article Title"},{"value":"Respiratory Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rmed.2015.02.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}