{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T23:35:47Z","timestamp":1790379347874,"version":"4.1.0"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"vor","delay-in-days":731,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100007509","name":"Sociedad Espa\u00f1ola de Neumolog\u00eda y Cirug\u00eda Tor\u00e1cica","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007509","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Societat Catalana de Pneumologia"},{"name":"Fundaci\u00f3n AstraZeneca"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","resmedjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Medicine"],"published-print":{"date-parts":[[2018,3]]},"DOI":"10.1016\/j.rmed.2018.02.008","type":"journal-article","created":{"date-parts":[[2018,2,13]],"date-time":"2018-02-13T11:54:54Z","timestamp":1518522894000},"page":"111-117","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"special_numbering":"C","title":["Identification of Pseudomonas aeruginosa and airway bacterial colonization by an electronic nose in bronchiectasis"],"prefix":"10.1016","volume":"136","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2320-6047","authenticated-orcid":false,"given":"Guillermo","family":"Suarez-Cuartin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordi","family":"Giner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Luis","family":"Merino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Rodrigo-Troyano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Feliu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lidia","family":"Perea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6800-5487","authenticated-orcid":false,"given":"Ferran","family":"Sanchez-Reus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4862-3595","authenticated-orcid":false,"given":"Diego","family":"Castillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2567-5496","authenticated-orcid":false,"given":"Vicente","family":"Plaza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James D.","family":"Chalmers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4833-6713","authenticated-orcid":false,"given":"Oriol","family":"Sibila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.rmed.2018.02.008_bib1","doi-asserted-by":"crossref","first-page":"i1","DOI":"10.1136\/thx.2010.136119","article-title":"British Thoracic Society guideline for non-CF bronchiectasis","volume":"65","author":"Pasteur","year":"2010","journal-title":"Thorax"},{"key":"10.1016\/j.rmed.2018.02.008_bib2","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1183\/13993003.00954-2015","article-title":"Bronchiectasis in Germany: a population-based estimation of disease prevalence","volume":"46","author":"Ringshausen","year":"2015","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.rmed.2018.02.008_bib3","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1183\/13993003.01033-2015","article-title":"Changes in the incidence, prevalence and mortality of bronchiectasis in the UK from 2004 to 2013: a population-based cohort study","volume":"47","author":"Quint","year":"2016","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.rmed.2018.02.008_bib4","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1378\/chest.10-0099","article-title":"Trends and burden of bronchiectasis-associated hospitalizations in the United States, 1993-2006","volume":"138","author":"Seitz","year":"2010","journal-title":"Chest"},{"key":"10.1016\/j.rmed.2018.02.008_bib5","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1177\/1479972316643698","article-title":"Annual direct medical costs of bronchiectasis treatment","volume":"13","author":"De La Rosa","year":"2016","journal-title":"Chron. Respir. Dis."},{"key":"10.1016\/j.rmed.2018.02.008_bib6","first-page":"1602","article-title":"A comprehensive analysis of the impact of Pseudomonas aeruginosa colonisation on prognosis in adult bronchiectasis","volume":"12","author":"Finch","year":"2015","journal-title":"Ann. Am. Thorac. Soc."},{"key":"10.1016\/j.rmed.2018.02.008_bib7","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1378\/chest.07-0490","article-title":"Factors associated with lung function decline in adult patients with stable non-cystic fibrosis bronchiectasis","volume":"132","author":"Mart\u00ednez-Garc\u00eda","year":"2007","journal-title":"Chest"},{"key":"10.1016\/j.rmed.2018.02.008_bib8","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1128\/jcm.25.5.758-762.1987","article-title":"Nonvalue of sputum culture in the management of lower respiratory tract infections","volume":"25","author":"Lentino","year":"1987","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.rmed.2018.02.008_bib9","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1183\/13993003.01899-2015","article-title":"Clinical phenotypes in adult patients with bronchiectasis","volume":"47","author":"Aliberti","year":"2016","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.rmed.2018.02.008_bib10","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1136\/thoraxjnl-2013-203739","article-title":"National BTS bronchiectasis audit 2012: is the quality standard being adhered to in adult secondary care?","volume":"69","author":"Hill","year":"2014","journal-title":"Thorax"},{"key":"10.1016\/j.rmed.2018.02.008_bib11","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1183\/13993003.00232-2016","article-title":"Quality standards for the management of bronchiectasis in Italy: a national audit","volume":"48","author":"Aliberti","year":"2016","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.rmed.2018.02.008_bib12","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1038\/nrmicro823","article-title":"Innovation: electronic noses and disease diagnostics","volume":"2","author":"Turner","year":"2004","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.rmed.2018.02.008_bib13","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1586\/14737159.2015.1043895","article-title":"Exhaled breath analysis by electronic nose in respiratory diseases","volume":"15","author":"Scarlata","year":"2015","journal-title":"Expert Rev. Mol. Diagn"},{"key":"10.1016\/j.rmed.2018.02.008_bib14","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1164\/rccm.200906-0939OC","article-title":"Exhaled breath profiling enables discrimination of chronic obstructive pulmonary disease and asthma","volume":"180","author":"Fens","year":"2009","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.rmed.2018.02.008_bib15","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1016\/j.jaci.2007.05.043","article-title":"An electronic nose in the discrimination of patients with asthma and controls","volume":"120","author":"Dragonieri","year":"2007","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.rmed.2018.02.008_bib16","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.jcf.2012.12.010","article-title":"Exhaled molecular profiles in the assessment of cystic fibrosis and primary ciliary dyskinesia","volume":"12","author":"Paff","year":"2013","journal-title":"J. Cyst. Fibros."},{"key":"10.1016\/j.rmed.2018.02.008_bib17","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1016\/j.rmed.2014.09.008","article-title":"Identification of airway bacterial colonization by an electronic nose in chronic obstructive pulmonary disease","volume":"108","author":"Sibila","year":"2014","journal-title":"Respir. Med."},{"key":"10.1016\/j.rmed.2018.02.008_bib18","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0135199","article-title":"Using the electronic nose to identify airway infection during COPD exacerbations","volume":"10","author":"Shafiek","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.rmed.2018.02.008_bib19","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/1471-2466-10-56","article-title":"2-Aminoacetophenone as a potential breath biomarker for Pseudomonas aeruginosa in the cystic fibrosis lung","volume":"10","author":"Scott-Thomas","year":"2010","journal-title":"BMC Pulm. Med."},{"key":"10.1016\/j.rmed.2018.02.008_bib20","doi-asserted-by":"crossref","first-page":"26010","DOI":"10.1088\/1752-7155\/7\/2\/026010","article-title":"Hydrogen cyanide concentrations in the breath of adult cystic fibrosis patients with and without Pseudomonas aeruginosa infection","volume":"7","author":"Gilchrist","year":"2013","journal-title":"J. Breath Res."},{"key":"10.1016\/j.rmed.2018.02.008_bib21","doi-asserted-by":"crossref","DOI":"10.1183\/23120541.00044-2015","article-title":"Exhaled breath hydrogen cyanide as a marker of early Pseudomonas aeruginosa infection in children with cystic fibrosis","volume":"1","author":"Gilchrist","year":"2015","journal-title":"ERJ Open Res."},{"key":"10.1016\/j.rmed.2018.02.008_bib22","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0115584","article-title":"Exhaled breath analysis using electronic nose in cystic fibrosis and primary ciliary dyskinesia patients with chronic pulmonary infections","volume":"9","author":"Joensen","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.rmed.2018.02.008_bib23","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1097\/00005537-200206000-00007","article-title":"Identification of upper respiratory bacterial pathogens with the electronic nose","volume":"112","author":"Lai","year":"2002","journal-title":"Laryngoscope"},{"key":"10.1016\/j.rmed.2018.02.008_bib24","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1157\/13128330","article-title":"Diagn\u00f3stico y tratamiento de las bronquiectasias","volume":"44","author":"Vendrell","year":"2008","journal-title":"Arch. Bronconeumol."},{"key":"10.1016\/j.rmed.2018.02.008_bib25","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1164\/rccm.201309-1575OC","article-title":"The bronchiectasis severity index an international derivation and validation study","volume":"189","author":"Chalmers","year":"2014","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.rmed.2018.02.008_bib26","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1183\/09031936.00026313","article-title":"Multidimensional approach to non-cystic fibrosis bronchiectasis: the FACED score","volume":"43","author":"Mart\u00ednez-Garc\u00eda","year":"2014","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.rmed.2018.02.008_bib27","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1136\/thx.2006.061648","article-title":"Standardisation of lung function testing: helpful guidance from the ATS\/ERS Task Force","volume":"61","author":"Laszlo","year":"2006","journal-title":"Thorax"},{"key":"10.1016\/j.rmed.2018.02.008_bib28","first-page":"217","article-title":"Spirometric reference values from a Mediterranean population","volume":"22","author":"Roca","year":"1986","journal-title":"Bull. Eur. Physiopathol. Respir."},{"key":"10.1016\/j.rmed.2018.02.008_bib29","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1111\/resp.12595","article-title":"Secreted mucins and airway bacterial colonization in non-CF bronchiectasis","volume":"20","author":"Sibila","year":"2015","journal-title":"Respirology"},{"key":"10.1016\/j.rmed.2018.02.008_bib30","first-page":"339","article-title":"Microscopic and baceriologic analysis of expectorated sputum","volume":"50","author":"Murray","year":"1975","journal-title":"Mayo Clin. Proc."},{"key":"10.1016\/j.rmed.2018.02.008_bib31","first-page":"431","article-title":"Inflammatory asthma phenotype discrimination using an electronic nose breath analyzer","volume":"25","author":"Plaza","year":"2015","journal-title":"J Investig. Allergol. Clin. Immunol."},{"key":"10.1016\/j.rmed.2018.02.008_bib32","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1016\/j.rmed.2007.03.009","article-title":"Microbiologic follow-up study in adult bronchiectasis","volume":"101","author":"King","year":"2007","journal-title":"Respir. Med."},{"key":"10.1016\/j.rmed.2018.02.008_bib33","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1164\/rccm.201203-0487OC","article-title":"Short- and long-term antibiotic treatment reduces airway and systemic inflammation in non-cystic fibrosis bronchiectasis","volume":"186","author":"Chalmers","year":"2012","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.rmed.2018.02.008_bib34","article-title":"Neutrophil elastase activity is associated with exacerbations and lung function decline in bronchiectasis","author":"Chalmers","year":"2016","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.rmed.2018.02.008_bib35","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1039\/b507392h","article-title":"Bacterial volatiles: the smell of small organisms","volume":"24","author":"Schulz","year":"2007","journal-title":"Nat. Prod. Rep."},{"key":"10.1016\/j.rmed.2018.02.008_bib36","doi-asserted-by":"crossref","first-page":"24001","DOI":"10.1088\/1752-7155\/6\/2\/024001","article-title":"Microbial volatile compounds in health and disease conditions","volume":"6","author":"Thorn","year":"2012","journal-title":"J. Breath Res."},{"key":"10.1016\/j.rmed.2018.02.008_bib37","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1186\/1465-9921-13-87","article-title":"Detection of Pseudomonas aeruginosa in sputum headspace through volatile organic compound analysis","volume":"13","author":"Goeminne","year":"2012","journal-title":"Respir. Res."},{"key":"10.1016\/j.rmed.2018.02.008_bib38","doi-asserted-by":"crossref","first-page":"1764","DOI":"10.1513\/AnnalsATS.201507-472OC","article-title":"Etiology of non-cystic fibrosis bronchiectasis in adults and its correlation to disease severity","volume":"12","author":"Lonni","year":"2015","journal-title":"Ann. Am. Thorac. Soc."},{"key":"10.1016\/j.rmed.2018.02.008_bib39","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/S2213-2600(16)30320-4","article-title":"Comorbidities and the risk of mortality in patients with bronchiectasis: an international multicentre cohort study","volume":"4","author":"McDonnell","year":"2016","journal-title":"Lancet Respir. Med"},{"key":"10.1016\/j.rmed.2018.02.008_bib40","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1136\/thorax.57.1.15","article-title":"Bacterial colonisation in patients with bronchiectasis: microbiological pattern and risk factors","volume":"57","author":"Angrill","year":"2002","journal-title":"Thorax"}],"container-title":["Respiratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611118300374?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0954611118300374?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T11:38:54Z","timestamp":1760614734000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0954611118300374"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3]]},"references-count":40,"alternative-id":["S0954611118300374"],"URL":"https:\/\/doi.org\/10.1016\/j.rmed.2018.02.008","relation":{},"ISSN":["0954-6111"],"issn-type":[{"value":"0954-6111","type":"print"}],"subject":[],"published":{"date-parts":[[2018,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identification of Pseudomonas aeruginosa and airway bacterial colonization by an electronic nose in bronchiectasis","name":"articletitle","label":"Article Title"},{"value":"Respiratory Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rmed.2018.02.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}